211 research outputs found

    Pasantía Internacional México

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    CD-T 624.193 G588; 24 pEn el último siglo, la ingeniería de túneles se ha convertido en uno de los principales motores del desarrollo socioeconómico de un país y en una señal inequívoca del papel de la infraestructura como pieza fundamental de dicho crecimiento. El siguiente trabajo indaga en la historia de la construcción y uso de túneles viales y de abastecimiento de agua en México y Colombia como una forma de entender, a través de un repaso histórico, el desarrollo de la ingeniería vial e hidráulica en los dos países latinoamericanos.Universidad Libre Seccional Pereir

    MANTENIMIENTO AUTOMOTRIZ BASADO EN UN DIAGNOSTICO TRIBOLÓGICO

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    En este trabajo se presenta un plan de mantenimiento automotriz basado en un diagnóstico tribológico del aceite lubricante de origen mineral grado SAE 20W50 multigrado, utilizado en la lubricación de un motor de combustión interna de cuatro cilindros, 1800 cm3, motor en posición diagonal, enfriado por anticongelante, con un sistema de lubricación por bomba mecánica. Las muestras se obtuvieron bajo diferentes condiciones de uso: 0km, 1000km, 5000km y 8500km; mismas que se sometieron a diversos ensayos, tales como: Viscosidad cinemática a 40°C y 100°C (Norma ASTM-D445), Desgaste (Norma ASTM G99-05), Timken (Norma ASTM-D-2782-17) y Análisis de Aceite; esto con la finalidad de diagnosticar la degradación del aceite lubricante y el desgaste generado, considerando estos resultados, se formuló un plan de mantenimiento automotriz basado en un diagnostico tribológico del aceite lubricante del motor en estudio

    Outstanding challenges in the transferability of ecological models

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    Predictive models are central to many scientific disciplines and vital for informing management in a rapidly changing world. However, limited understanding of the accuracy and precision of models transferred to novel conditions (their ‘transferability’) undermines confidence in their predictions. Here, 50 experts identified priority knowledge gaps which, if filled, will most improve model transfers. These are summarized into six technical and six fundamental challenges, which underlie the combined need to intensify research on the determinants of ecological predictability, including species traits and data quality, and develop best practices for transferring models. Of high importance is the identification of a widely applicable set of transferability metrics, with appropriate tools to quantify the sources and impacts of prediction uncertainty under novel conditions

    Reflexión Política. Volumen 6 No. 11 de 2004

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    La Asociación Latinoamericana de Ciencia Política ha sido creada con el objetivo de coordinar, hacer más visible y potenciar las actividades de la disciplina de la región. Son miembros fundadores los participantes y asistentes al “1er Congreso Latinoamericano de Ciencia Política”, celebrado en la ciudad de Salamanca, España, los días 9, 10 y 11 de julio de 2002. Tiene como objetivos contribuir al perfeccionamiento de la disciplina en la región latinoamericana, facilitar el intercambio de información (principalmente a través de la publicación periódica de un boletín informativo) y otras formas de cooperación técnica entre sus miembros, apoyar los procesos de reforma y modernización de los sistemas políticos de la región y celebrar Congresos bianuales. La Secretaría de la Asociación tiene su sede en la Universidad de Salamanca. Esta Secretaría procurará establecer una red con los asociados para facilitar el intercambio y flujos de información entre los mismos.The Latin American Association of Political Science has been created with the objective of coordinating, making more visible and enhancing the activities of the discipline in the region. Founding members are the participants and attendees of the “1st Latin American Congress of Political Science”, held in the city of Salamanca, Spain, on July 9, 10 and 11, 2002. Its objectives are to contribute to the improvement of the discipline in the Latin American region, facilitate the exchange of information (mainly through the periodic publication of a newsletter) and other forms of technical cooperation among its members, support the reform and modernization processes of the political systems of the region and hold biannual Congresses. The Association's Secretariat has its headquarters at the University of Salamanca. This The Secretariat will seek to establish a network with partners to facilitate the exchange and flows of information between them

    Protecting 30% of the planet for nature: costs, benefits, and economic implications:Working paper analysing the economic implications of the proposed 30% target for areal protection in the draft post-2020 Global Biodiversity Framework

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    Protecting 30% of the planet for nature: costs, benefits, and economic implications:Working paper analysing the economic implications of the proposed 30% target for areal protection in the draft post-2020 Global Biodiversity Framework

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    Working paper analysing the economic implications of the proposed 30% target for areal protection in the draft post-2020 Global Biodiversity Framewor

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    58 pages, 5 figures, 3 tables- The World Economic Forum now ranks biodiversity loss as a top-five risk to the global economy, and the draft post-2020 Global Biodiversity Framework proposes an expansion of conservation areas to 30% of the earth’s surface by 2030 (hereafter the “30% target”), using protected areas (PAs) and other effective area-based conservation measures (OECMs). - Two immediate concerns are how much a 30% target might cost and whether it will cause economic losses to the agriculture, forestry and fisheries sectors. - Conservation areas also generate economic benefits (e.g. revenue from nature tourism and ecosystem services), making PAs/Nature an economic sector in their own right. - If some economic sectors benefit but others experience a loss, high-level policy makers need to know the net impact on the wider economy, as well as on individual sectors. [...]A. Waldron, K. Nakamura, J. Sze, T. Vilela, A. Escobedo, P. Negret Torres, R. Button, K. Swinnerton, A. Toledo, P. Madgwick, N. Mukherjee were supported by National Geographic and the Resources Legacy Fund. V. Christensen was supported by NSERC Discovery Grant RGPIN-2019-04901. M. Coll and J. Steenbeek were supported by EU Horizon 2020 research and innovation programme under grant agreement No 817578 (TRIATLAS). D. Leclere was supported by TradeHub UKRI CGRF project. R. Heneghan was supported by Spanish Ministry of Science, Innovation and Universities, Acciones de Programacion Conjunta Internacional (PCIN-2017-115). M. di Marco was supported by MIUR Rita Levi Montalcini programme. A. Fernandez-Llamazares was supported by Academy of Finland (grant nr. 311176). S. Fujimori and T. Hawegawa were supported by The Environment Research and Technology Development Fund (2-2002) of the Environmental Restoration and Conservation Agency of Japan and the Sumitomo Foundation. V. Heikinheimo was supported by Kone Foundation, Social Media for Conservation project. K. Scherrer was supported by the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme under grant agreement No 682602. U. Rashid Sumaila acknowledges the OceanCanada Partnership, which funded by the Social Sciences and Humanities Research Council of Canada (SSHRC). T. Toivonen was supported by Osk. Huttunen Foundation & Clare Hall college, Cambridge. W. Wu was supported by The Environment Research and Technology Development Fund (2-2002) of the Environmental Restoration and Conservation Agency of Japan. Z. Yuchen was supported by a Ministry of Education of Singapore Research Scholarship Block (RSB) Research FellowshipPeer reviewe

    Effect of SGLT2 inhibitors on stroke and atrial fibrillation in diabetic kidney disease: Results from the CREDENCE trial and meta-analysis

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    BACKGROUND AND PURPOSE: Chronic kidney disease with reduced estimated glomerular filtration rate or elevated albuminuria increases risk for ischemic and hemorrhagic stroke. This study assessed the effects of sodium glucose cotransporter 2 inhibitors (SGLT2i) on stroke and atrial fibrillation/flutter (AF/AFL) from CREDENCE (Canagliflozin and Renal Events in Diabetes With Established Nephropathy Clinical Evaluation) and a meta-Analysis of large cardiovascular outcome trials (CVOTs) of SGLT2i in type 2 diabetes mellitus. METHODS: CREDENCE randomized 4401 participants with type 2 diabetes mellitus and chronic kidney disease to canagliflozin or placebo. Post hoc, we estimated effects on fatal or nonfatal stroke, stroke subtypes, and intermediate markers of stroke risk including AF/AFL. Stroke and AF/AFL data from 3 other completed large CVOTs and CREDENCE were pooled using random-effects meta-Analysis. RESULTS: In CREDENCE, 142 participants experienced a stroke during follow-up (10.9/1000 patient-years with canagliflozin, 14.2/1000 patient-years with placebo; hazard ratio [HR], 0.77 [95% CI, 0.55-1.08]). Effects by stroke subtypes were: ischemic (HR, 0.88 [95% CI, 0.61-1.28]; n=111), hemorrhagic (HR, 0.50 [95% CI, 0.19-1.32]; n=18), and undetermined (HR, 0.54 [95% CI, 0.20-1.46]; n=17). There was no clear effect on AF/AFL (HR, 0.76 [95% CI, 0.53-1.10]; n=115). The overall effects in the 4 CVOTs combined were: Total stroke (HRpooled, 0.96 [95% CI, 0.82-1.12]), ischemic stroke (HRpooled, 1.01 [95% CI, 0.89-1.14]), hemorrhagic stroke (HRpooled, 0.50 [95% CI, 0.30-0.83]), undetermined stroke (HRpooled, 0.86 [95% CI, 0.49-1.51]), and AF/AFL (HRpooled, 0.81 [95% CI, 0.71-0.93]). There was evidence that SGLT2i effects on total stroke varied by baseline estimated glomerular filtration rate (P=0.01), with protection in the lowest estimated glomerular filtration rate (45 mL/min/1.73 m2]) subgroup (HRpooled, 0.50 [95% CI, 0.31-0.79]). CONCLUSIONS: Although we found no clear effect of SGLT2i on total stroke in CREDENCE or across trials combined, there was some evidence of benefit in preventing hemorrhagic stroke and AF/AFL, as well as total stroke for those with lowest estimated glomerular filtration rate. Future research should focus on confirming these data and exploring potential mechanisms
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