100 research outputs found
Das Narrative Policy Framework: Ein Reiseführer für Policy-Narrative
The last decade has seen the rise of the Narrative Policy Framework (NPF) as a valuable theoretical framework for advancing knowledge of the policy process. In this article, we investigate the NPF’s “travel” capacities across geographies, political systems, policy fields, levels of analysis, methodological approaches, and other theories of the policy process. We assess these capabilities by reviewing extant research and mapping newly explored territories. While we find that the NPF embodies all necessary conditions to travel to different settings, the empirical applications remain largely confined to the U.S. and European contexts, environmental policy, the meso level of analysis, the use of content analysis of documents as a methodological approach, and only a few combinations with other theories of the policy process. Our findings indicate that the NPF can travel well. However, we call for further research to conceptualize the NPF’s macro level, to replicate NPF scholarship beyond liberal democratic institutional contexts, and to affirm the framework’s capacity to be generalizable in varied settings.In den letzten zehn Jahren hat sich das Narrative Policy Framework (NPF) zum wegweisenden theoretischen Rahmen bei der Erklärung der Rolle von Narrativen in Politikgestaltungsprozessen entwickelt. Dieser Artikel untersucht die Kapazitäten des NPF, in anderen Regionen und politischen Systemen, neuen Politikfeldern, Analyseebenen und methodologischen Ansätzen sowie in Kombination mit weiteren Theorien des Politikprozesses angewandt zu werden. Diese „Reisefähigkeit“ des NPF wird anhand eines systematischen Reviews der bestehenden NPF-Literatur bewertet. Dabei werden neue, kürzlich erkundete Territorien speziell hervorgehoben. Das systematische Review zeigt, dass das NPF zwar alle notwendigen Bedingungen erfüllt, um in verschiedene Umgebungen zu reisen. Trotzdem beschränken sich bisherige empirische Anwendungen des NPF weitgehend auf die amerikanischen und europäischen Kontexte, die Umweltpolitik, die Meso-Ebene der Analyse, die Inhaltsanalyse von Dokumenten und auf nur wenige Kombinationen mit anderen Theorien des Politikprozesses. Diese Ergebnisse weisen darauf hin, dass das NPF grundsätzlich gut reisen kann. Wir fordern jedoch weitere Forschung, um die Makro-Ebene des NPF zu konzeptualisieren, NPF-Forschung außerhalb von liberal-demokratischen Systemen zu replizieren und die Generalisierbarkeit des NPF in verschiedenen Kontexten zu bestätigen
The Deformation of an Elastic Substrate by a Three-Phase Contact Line
Young's classic analysis of the equilibrium of a three-phase contact line
ignores the out-of-plane component of the liquid-vapor surface tension. While
it has long been appreciated that this unresolved force must be balanced by
elastic deformation of the solid substrate, a definitive analysis has remained
elusive because conventional idealizations of the substrate imply a divergence
of stress at the contact line. While a number of theories of have been
presented to cut off the divergence, none of them have provided reasonable
agreement with experimental data. We measure surface and bulk deformation of a
thin elastic film near a three-phase contact line using fluorescence confocal
microscopy. The out-of-plane deformation is well fit by a linear elastic theory
incorporating an out-of-plane restoring force due to the surface tension of the
gel. This theory predicts that the deformation profile near the contact line is
scale-free and independent of the substrate elastic modulus.Comment: 4 pages, 3 figure
Salient practices of award-winning undergraduate research mentors: Balancing freedom and control to achieve excellence
This paper contributes to research on teaching excellence by extending the current body of literature pertaining to mentoring pedagogies in undergraduate research settings across diverse social, institutional and disciplinary contexts. Our data comes from in-depth interviews with 32 international faculty who have received excellence awards for undergraduate research mentoring. The data reveal a freedom - control dialectic, illuminating the ways in which expert mentors negotiate the desire to create opportunities for students to experience freedom and creativity in research, yet maintain control over the topic, quality and outcomes. The research findings reveal a defining characteristic of award-winning mentors as an ability to establish and sustain a sense of challenge, while maintaining meaningful engagement and a sense of achievement amongst students. The findings show the importance of tailoring practice to the needs of particular student groups, and there are implications for institutional resourcing, as well as mentor training and development
Time to abandon the hygiene hypothesis: new perspectives on allergic disease, the human microbiome, infectious disease prevention and the role of targeted hygiene.
AIMS: To review the burden of allergic and infectious diseases and the evidence for a link to microbial exposure, the human microbiome and immune system, and to assess whether we could develop lifestyles which reconnect us with exposures which could reduce the risk of allergic disease while also protecting against infectious disease. METHODS: Using methodology based on the Delphi technique, six experts in infectious and allergic disease were surveyed to allow for elicitation of group judgement and consensus view on issues pertinent to the aim. RESULTS: Key themes emerged where evidence shows that interaction with microbes that inhabit the natural environment and human microbiome plays an essential role in immune regulation. Changes in lifestyle and environmental exposure, rapid urbanisation, altered diet and antibiotic use have had profound effects on the human microbiome, leading to failure of immunotolerance and increased risk of allergic disease. Although evidence supports the concept of immune regulation driven by microbe-host interactions, the term 'hygiene hypothesis' is a misleading misnomer. There is no good evidence that hygiene, as the public understands, is responsible for the clinically relevant changes to microbial exposures. CONCLUSION: Evidence suggests a combination of strategies, including natural childbirth, breast feeding, increased social exposure through sport, other outdoor activities, less time spent indoors, diet and appropriate antibiotic use, may help restore the microbiome and perhaps reduce risks of allergic disease. Preventive efforts must focus on early life. The term 'hygiene hypothesis' must be abandoned. Promotion of a risk assessment approach (targeted hygiene) provides a framework for maximising protection against pathogen exposure while allowing spread of essential microbes between family members. To build on these findings, we must change public, public health and professional perceptions about the microbiome and about hygiene. We need to restore public understanding of hygiene as a means to prevent infectious disease
Mentor perspectives on the place of undergraduate research mentoring in academic identity and career development: An analysis of award winning mentors
The aim of this study was to determine how Undergraduate Research (UR) mentoring fits into the career profile of award-winning UR mentors and to determine the factors that motivate engagement as UR mentor. Twenty-four award-winning UR mentors based in four countries were interviewed about their mentoring practices. Six themes emerged: 1) Academic Identity and Motivations; 2) Challenges to Academic Identity and Career Development; 3) Enhanced Research Productivity; 4) Recognition and Reward; 5) Institution Values Commitment and 6) Developing Other Mentors. In addition to explaining these themes, the authors discuss how the findings can be utilized for academic development and identity formation for faculty
Exploring Adaptive Management for Greater Sage Grouse in Northern Montana in the Face of Climate Change
A collaboration has begun in Montana among several state and federal agencies and non-governmental organizations interested in the management of greater sage grouse (Centrocercus urophasianus) in a > 5,000,000-ac (> 20,234-ha) landscape including the Charles M. Russell National Wildlife Refuge. The first step was conducting personal interviews with field biologists and managers in the general area to assess what management actions they are making. Using this information, we conducted an on-line survey to further identify those actions and how they are made. Finally, almost 40 managers and scientists met to discuss whether an adaptive management approach might be useful to gain an understanding of the interaction among habitats and management actions and how this will be affected by annual weather and climate patterns. A conceptual model of how these factors affect the life cycle of grouse has been drafted, and we are gathering comments on it. The intent is for that to be used as an ecological response model for assessing the effects of possible climate change scenarios. Future work will entail: (1) further delineation of management actions and the social networks associated with them, (2) building and evaluating a working model using rapid prototype methods, (3) conducting futures analyses of associated landscapes, (4) continuing to foster collaborative effort, and (5) working one-onone with managers to evaluate model and adaptive management applicability using such tools as LCMAP (Landscape Conservation Management and Analysis Portal)
ATA Practice Guidelines for Live, On-Demand Primary and Urgent Care
Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/140286/1/tmj.2015.0008.pd
Nature-Based Interventions for Improving Health and Wellbeing : The Purpose, the People and the Outcomes
Engagement with nature is an important part of many people's lives, and the health and wellbeing benefits of nature-based activities are becoming increasingly recognised across disciplines from city planning to medicine. Despite this, urbanisation, challenges of modern life and environmental degradation are leading to a reduction in both the quantity and the quality of nature experiences. Nature-based health interventions (NBIs) can facilitate behavioural change through a somewhat structured promotion of nature-based experiences and, in doing so, promote improved physical, mental and social health and wellbeing. We conducted a Delphi expert elicitation process with 19 experts from seven countries (all named authors on this paper) to identify the different forms that such interventions take, the potential health outcomes and the target beneficiaries. In total, 27 NBIs were identified, aiming to prevent illness, promote wellbeing and treat specific physical, mental or social health and wellbeing conditions. These interventions were broadly categorized into those that change the environment in which people live, work, learn, recreate or heal (for example, the provision of gardens in hospitals or parks in cities) and those that change behaviour (for example, engaging people through organized programmes or other activities). We also noted the range of factors (such as socioeconomic variation) that will inevitably influence the extent to which these interventions succeed. We conclude with a call for research to identify the drivers influencing the effectiveness of NBIs in enhancing health and wellbeing.Peer reviewe
The Appearance and Modulation of Osteocyte Marker Expression during Calcification of Vascular Smooth Muscle Cells
Vascular calcification is an indicator of elevated cardiovascular risk. Vascular smooth muscle cells (VSMCs), the predominant cell type involved in medial vascular calcification, can undergo phenotypic transition to both osteoblastic and chondrocytic cells within a calcifying environment.In the present study, using in vitro VSMC calcification studies in conjunction with ex vivo analyses of a mouse model of medial calcification, we show that vascular calcification is also associated with the expression of osteocyte phenotype markers. As controls, the terminal differentiation of murine calvarial osteoblasts into osteocytes was induced in vitro in the presence of calcifying medium (containing ß-glycerophosphate and ascorbic acid), as determined by increased expression of the osteocyte markers DMP-1, E11 and sclerostin. Culture of murine aortic VSMCs under identical conditions confirmed that the calcification of these cells can also be induced in similar calcifying medium. Calcified VSMCs had increased alkaline phosphatase activity and PiT-1 expression, which are recognized markers of vascular calcification. Expression of DMP-1, E11 and sclerostin was up-regulated during VSMC calcification in vitro. Increased protein expression of E11, an early osteocyte marker, and sclerostin, expressed by more mature osteocytes was also observed in the calcified media of Enpp1(-/-) mouse aortic tissue.This study has demonstrated the up-regulation of key osteocytic molecules during the vascular calcification process. A fuller understanding of the functional role of osteocyte formation and specifically sclerostin and E11 expression in the vascular calcification process may identify novel potential therapeutic strategies for clinical intervention
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