The Sequential Costs of Poverty: What Traditional Measures Overlook

This research note proposes an addition to the poverty measurement debate. Motivated by dissatisfaction with the official poverty measure, which many scholars and practitioners share, we propose the use of sequential costs of poverty to enrich the poverty measure so that it might capture more closely the life-experiences of low-income families. After presenting some background on poverty measurement, this research note explores the conceptual framework that surrounds the notion of sequential costs. Drawing on our past research, we propose ways in which these sequential costs surface, with illustrative examples from health, employment, housing, and income maintenance

The Relationship between Empathy and Attitudes toward Government Intervention

Throughout history, government policy and programs have played integral roles in shaping social services. This article reports the findings of a study that explored the relationship between interpersonal empathy and attitudes toward government intervention among college students. Findings suggest that increased levels of empathy are associated with more positive attitudes toward government intervention. This relationship is even stronger for participants from marginalized identity groups. Nurturing empathy among those engaged in social welfare policy-making may support government efforts that are in the best interest of communities they are intended to help

Social Empathy: Using Interpersonal Skills to Effect Change

Keynote speaker: Dr. Elizabeth A. Segal, Professor, School of Social Work, Arizona State University - "Social Empathy: Using Interpersonal Skills to Effect Change".The Ohio State University College of Social Wor

Polarized Signaling Endosomes Coordinate BDNF-Induced Chemotaxis of Cerebellar Precursors

During development, neural precursors migrate in response to positional cues such as growth factor gradients. However, the mechanisms that enable precursors to sense and respond to such gradients are poorly understood. Here we show that cerebellar granule cell precursors (GCPs) migrate along a gradient of brain-derived neurotrophic factor (BDNF), and we demonstrate that vesicle trafficking is critical for this chemotactic process. Activation of TrkB, the BDNF receptor, stimulates GCPs to secrete BDNF, thereby amplifying the ambient gradient. The BDNF gradient stimulates endocytosis of TrkB and associated signaling molecules, causing asymmetric accumulation of signaling endosomes at the subcellular location where BDNF concentration is maximal. Thus, regulated BDNF exocytosis and TrkB endocytosis enable precursors to polarize and migrate in a directed fashion along a shallow BDNF gradient

Review: The Journal of Dramaturgy, volume 26, issue 1

Contents include: Editors\u27 Note; When Fierceness and Kindness Collide: The Dramaturgy of a Drag Storytime; Trauma-Informed Approaches to Dramaturgy and Rehearsal: An Exploration of Daphne’s Dive in the Time of COVID-19; Reframing Shakespeare\u27s Taming to Rally for Political Change; Relational Audience Engagement in Guarded Girls: A Critical Reflection.https://soundideas.pugetsound.edu/lmdareview/1055/thumbnail.jp

Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke

Genetic factors have been implicated in stroke risk but few replicated associations have been reported. We conducted a genome-wide association study (GWAS) in ischemic stroke and its subtypes in 3,548 cases and 5,972 controls, all of European ancestry. Replication of potential signals was performed in 5,859 cases and 6,281 controls. We replicated reported associations between variants close to PITX2 and ZFHX3 with cardioembolic stroke, and a 9p21 locus with large vessel stroke. We identified a novel association for a SNP within the histone deacetylase 9(HDAC9) gene on chromosome 7p21.1 which was associated with large vessel stroke including additional replication in a further 735 cases and 28583 controls (rs11984041, combined P = 1.87×10−11, OR=1.42 (95% CI) 1.28-1.57). All four loci exhibit evidence for heterogeneity of effect across the stroke subtypes, with some, and possibly all, affecting risk for only one subtype. This suggests differing genetic architectures for different stroke subtypes

Radio galaxy zoo EMU: towards a semantic radio galaxy morphology taxonomy

© 2023 The Author(s). Published by Oxford University Press on behalf of Royal Astronomical Society. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/)We present a novel natural language processing (NLP) approach to deriving plain English descriptors for science cases otherwise restricted by obfuscating technical terminology. We address the limitations of common radio galaxy morphology classifications by applying this approach. We experimentally derive a set of semantic tags for the Radio Galaxy Zoo EMU (Evolutionary Map of the Universe) project and the wider astronomical community. We collect 8486 plain English annotations of radio galaxy morphology, from which we derive a taxonomy of tags. The tags are plain English. The result is an extensible framework, which is more flexible, more easily communicated, and more sensitive to rare feature combinations, which are indescribable using the current framework of radio astronomy classifications.Peer reviewe