Tortillas y Lagrimas (Tortillas and Tears)

With my MFA in Dance Thesis Tortillas y Lagrimas (Tortillas and Tears), I share my experience as a Mexican American Latina woman in the United States, tracking back through my family heritage. As elements of my research, I studied Mexican immigration experiences (particularly my grandmother’s), Aztec Dance, digital media for dance, and improvisational practice in the post modern and contemporary dance field. I took classes, conducted oral interviews, attended conferences, and created Dance Labs for experiential exploration. These influences are synthesized in my MFA thesis performance, a dance concert presenting twelve choreographic dance works with traditional Mexican folk music and mariachi music as well as digital media components. Tortillas y Lagrimas (Tortillas and Tears) premiered on April 6, 2018 at Talento Bilingüe de Houston, and featured my public high school dance students, two professional dancers, and myself. I began my research with a personal investigation and left with a deeper connection to my Mexican and Mexican American culture and heritage, which I plan to continue to explore as a dance artist

A polymorphic enhancer near GREM1 influences bowel cancer risk through differential CDX2 and TCF7L2 binding

Under a Creative Commons license.-- et al.A rare germline duplication upstream of the bone morphogenetic protein antagonist GREM1 causes aMendelian-dominant predisposition to colorectal cancer (CRC). The underlying disease mechanism is strong, ectopic GREM1 overexpression in the intestinal epithelium. Here, we confirm that a common GREM1 polymorphism, rs16969681, is also associated with CRC susceptibility, conferring ~20% differential risk in the general population. We hypothesized the underlying cause to be moderate differences inGREM1 expression. We showed that rs16969681 lies in a region of active chromatin with allele- and tissue-specific enhancer activity. The CRC high-risk allele was associated with stronger gene expression, and higher Grem1 mRNA levels increased the intestinal tumor burden in ApcMin mice. The intestine-specific transcription factor CDX2 and Wnt effector TCF7L2 bound near rs16969681, with significantly higher affinity for the risk allele, and CDX2 overexpression in CDX2/GREM1-negative cells caused re-expression of GREM1. rs16969681 influences CRC risk through effects on Wnt-driven GREM1 expression in colorectal tumors. © 2014 The Authors.Funding was provided from Cancer Research UK grant A/16459, an EU FP7 SYSCOL Consortium grant, and the EU COST colorectal cancer initiative. Core funding to the Wellcome Trust Centre for Human Genetics was provided from the Wellcome Trust (090532/Z/09/Z). J.L.G.-S. and J.J.C. were supported by the Spanish/FEDER government grants BFU2010-14839 and BFU2011-2292.Open Access funded by Wellcome Trust.Peer Reviewe

Cuidado humanizado de enfermería según la teoría de Jean Watson, servicio de medicina del Hospital Daniel Alcides Carrión. Lima-Callao, 2015

El Cuidado Humanizado es una necesidad que urge en la práctica profesional y esto se evidencia en las políticas, disposiciones normativas establecidas por las entidades de salud que velan por el derecho de los pacientes y garantizan la calidad del servicio que se brinda. Objetivo: determinar el Cuidado Humanizado que brinda el profesional de Enfermería según la Teoría de Jean Watson, Servicio de Medicina del Hospital Daniel Alcides Carrión. Material y métodos: la población total estuvo conformada 46 profesionales de Enfermería que laboran en los Servicios de Medicina. Resultados: que el Cuidado Humano que ofrece los enfermeros es regular en un 52%, mientras que el 26%, es alto. Según las dimensiones: Satisfacción de necesidades: el cuidado humano e 59% ofrece regular, mientras que el 30% es alto; Habilidades, técnicas de enfermería el cuidado humano de regular 91%, y el nivel bajo 9%. Autocuidado de la profesional es el cuidado humano de regular un 57%, mientras 24% bajo. Aspectos éticos del cuidado el 65% en cuidado humano de regular y el 13% bajo. Relación enfermera- paciente el 65% en cuidado humano de regular, y el 20% Alto. Aspectos espirituales en un 87% en cuidado humano de regular, un 4% bajo. Conclusión: el cuidado humanizado es dado en forma regular y es necesario implementar estrategias, planes de mejoras y capacitación continua con la fnalidad de generar la sensibilización del personal de enfermería para aplicar buen trato al paciente desde un abordaje basado en valores humanos

The role of anaemia in oxidative and genotoxic damage in transfused β-thalassaemic patients.

Redox imbalance and genotoxic damage are commonly observed in β thalassaemic patients. The aim of this study was to assess the role of anaemia in oxidative and genotoxic damage in regularly transfused thalassaemic patients, undergoing iron chelation therapy.We studied the relationships of haematological, biochemical and clinical parameters with oxidative (reactive oxygen species and 8-oxo-7,8-dihydro-2'-deoxyguanosine) and genotoxic biomarkers (Comet assay and cytokinesis-block micronucleus test) in blood samples from 105 patients. To reduce the early effect of redox-active iron, samples were collected when pharmacokinetics of the iron chelators ensured their maximum effectiveness. The transfusion regimen, cardiac and hepatic magnetic resonance imaging T2* were evaluated to characterize the patient cohort. Labile plasma iron (LPI) was also assayed.Haemoglobin level had a significant effect on ROS, %DNA in the tail and micronuclei-micronucleated cell frequency (p  0.05). Higher Hb values reduced redox imbalance. LPI, detectable in 50.5% of patients, was related to the number of apoptotic and necrotic lymphocytes (p = 0.03), demonstrating the cytotoxic effect of iron.The results highlight that an adequate transfusion regimen is essential to limit oxidative and genotoxic damage in β-thalassemic patients undergoing chelation therapy.Owing to the higher risk of cancer in the thalassaemic cohorts, specific genotoxicity/oxidative biomarkers should be monitored in order to ameliorate and formulate more personalized disease management

Responsabilidad social universitaria ante la inclusión educativa y social: generando una cultura de diversidad

Se presenta una memoria final del PIMCD nº 36 del cuso 2014-2015 en el que se ha desarrollado una herramienta online con bibliografía, documentación, enlaces de interés, materiales de aplicación en el aula y trabajos de los estudiantes para atender a diversidades funcionales, culturales, sexo-genéricas e invisibles en el sistema educativa

Daily sitting time and its association with non-communicable diseases and multimorbidity in Catalonia

Background: Non-communicable diseases (NCDs) account for 71% of deaths worldwide and individual behaviours such as sedentariness play an important role on their development and management. However, the detrimental effect of daily sitting on multiple NCDs has rarely been studied. This study sought (i) to investigate the association between sitting time and main NCDs and multimorbidity in the population of Catalonia and (ii) to explore the effect of physical activity as a modifier of the associations between sitting time and health outcomes. Methods: Cross-sectional data from the 2016 National Health Survey of Catalonia were analyzed, and multivariable logistic regression, adjusting for socio-demographics and individual risk factors (tobacco and alcohol consumption, diet, hyperlipidaemia, hypertension, body mass index) was used to estimated odds ratios (ORs) and 95% confidence intervals (CIs) of the association between sitting time and NCDs. Results: A total of 3320 people 15 years old were included in the study. Sitting more than 5 h/day was associated with a higher risk of cardiovascular disease (OR 1.90, 95% CI: 1.21-2.97), respiratory disease (OR 1.61, 95% CI: 1.13-2.30) and multimorbidity (OR 2.80, 95% CI: 1.53-5.15). Sitting more than 3 h/day was also associated with a higher risk of multimorbidity (OR 2.26, 95% CI: 1.23-4.16). Physical activity did not modify the associations between sitting time and any of the outcomes. Conclusions: Daily sitting time might be an independent risk factor for some NCDs, such as cardiovascular disease, respiratory disease and multimorbidity, independently of the level risk of physical inactivity

Dosificación de hormigón autocompactante reforzado con fibras de acero basado en el estudio de la reología de la pasta

[ES] Este trabajo presenta un método de diseño de hormigón autocompactante reforzado con fibras de acero (HACRFA) que se basa en un modelo de reología de pasta de cemento, a partir del cual se determina la viscosidad plástica de la misma mediante la relación aguamateriales cementíceos, y en un modelo micromecánico que permite estimar la viscosidad plástica efectiva del HACRFA. Son datos necesarios los valores deseados de resistencia a compresión y de viscosidad efectiva del HACRFA, así como la fracción en volumen de fibra de acero a emplear y su esbeltez. Por medio de unos sencillos gráficos de diseño, particulares para cada resistencia a compresión, se calculan las cantidades de los distintos componentes del HACRFA.Los autores agradecen la financiación recibida al Ministerio de Economía y Competitividad a través del proyecto BIA2015-68678-C2-1-R. A. de la Rosa agradece la ayuda económica recibida mediante la beca FPI BES-2016-077458. Así como al Instituto de Cerámica y Vidrio del CSIC, en especial al Profesor de Investigación Rodrigo Moreno por la ayuda y el instrumental para la medición de la viscosidad.Rosa Velasco, ADL.; Poveda Bautista, E.; Cifuentes Bulte, H.; Ruiz López, G. (2018). Dosificación de hormigón autocompactante reforzado con fibras de acero basado en el estudio de la reología de la pasta. En HAC 2018. V Congreso Iberoamericano de hormigón autocompactable y hormigones especiales. Editorial Universitat Politècnica de València. 33-44. https://doi.org/10.4995/HAC2018.2018.5645OCS334

16,16-Dimethyl Prostaglandin E-2 Efficacy on Prevention and Protection from Bleomycin-Induced Lung Injury and Fibrosis

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Alternativas para prevenir o corregir trastornos de conducta en niños con necesidades educativas especiales : Orientación familiar

Resulta indiscutible que los trastornos de conducta que presentan algunos niños y adolescentes constituye un problema aun no resuelto. Desde un enfoque educativo se ha tratado de desarrollar métodos y procedimientos que estén dirigidos a prevenir o corregir determinados trastornos, influenciando directamente en el seno familiar, por lo que nuestro trabajo está encaminado a la instrumentación de un conjunto de actividades que tienen por objeto darle solución a los problemas planteados, en niños con necesidades educativas especiales, con la participación activa de la familia. Su efectividad ha sido demostrada en la práctica de nuestro quehacer educativo.Eje: Educación primaria: experiencias educativasRed de Universidades con Carreras en Informática (RedUNCI