563 research outputs found
Classification and unscrambling a class-inside-class situation by object target rotation : Hungarian silver coins of the Árpád Dynasty, 997 – 1301 AD
Classification is an important part of chemometrics and mostly based on optimization by
vector rotations. The present study is a continuation of the classification of medieval
Hungarian silver coins including the 16 kings of the Hungarian Árpád Dynasty (997AD –
1301AD) (Rácz et al.: Heritage Science 2013 1:2) The Rácz et al. paper identified three
historical periods of the Árpád Dynasty from chemical data. The aim of the present study is to
test whether the classification could be further refined by marker object projection aided
classification. It offers an example of the efficiency of this method in unscrambling a classinside-
class situation.
The frequency distribution of concentrations of the coins are skewed and to a certain
extent bi- modal, and the arithmetic mean value and standard deviation around the mean
frequently used in parametric methods may be poor descriptors of the information carried by
the data. We test a combination of principal components decomposition and the nonparametric,
non-iterative object target rotation method to overcome some of the theoretical
limitations of parametric methods. This test includes identification of archetypical class
―Ambassadors‖ of each of the three historical periods of the Árpád Dynasty and shows a
class-inside-class situation
Micro-RNA Binding Site Polymorphisms in the WFS1 Gene Are Risk Factors of Diabetes Mellitus
The absolute or relative lack of insulin is the key factor in the pathogenesis of diabetes mellitus. Although the connection between loss of function mutations of the WFS1 gene and DIDMOAD-syndrome including diabetes mellitus underpins the significance of wolframin in the pathogenesis, exact role of WFS1 polymorphic variants in the development of type 1 and type 2 diabetes has not been discovered yet. In this analysis, 787 patients with diabetes and 900 healthy people participated. Genotyping of the 7 WFS1 SNPs was carried out by TaqMan assays. Association study was performed by chi2-test in combination with correction for multiple testing. For functional analysis, the entire 3' UTR of the WFS1 gene was subcloned in a pMIR-Report plasmid and relative luciferase activities were determined. Linkage disequilibrium analysis showed a generally high LD within the investigated region, however the rs1046322 locus was not in LD with the other SNPs. The two miR-SNPs, rs1046322 and rs9457 showed significant association with T1DM and T2DM, respectively. Haplotype analysis also confirmed the association between the 3' UTR loci and both disease types. In vitro experiments showed that miR-185 reduces the amount of the resulting protein, and rs9457 miRSNP significantly influences the rate of reduction in a luciferase reporter assay. Genetic variants of the WFS1 gene might contribute to the genetic risk of T1DM and T2DM. Furthermore demonstrating the effect of rs9457 in binding of miR-185, we suggest that the optimal level of wolframin protein, potentially influenced by miR-regulation, is crucial in normal beta cell function
Uniform existence of the integrated density of states for random Schr\"odinger operators on metric graphs over
We consider ergodic random magnetic Schr\"odinger operators on the metric
graph with random potentials and random boundary conditions
taking values in a finite set. We show that normalized finite volume eigenvalue
counting functions converge to a limit uniformly in the energy variable. This
limit, the integrated density of states, can be expressed by a closed
Shubin-Pastur type trace formula. It supports the spectrum and its points of
discontinuity are characterized by existence of compactly supported
eigenfunctions. Among other examples we discuss percolation models.Comment: 17 pages; typos removed, references updated, definition of subgraph
densities explaine
Notions of Infinity in Quantum Physics
In this article we will review some notions of infiniteness that appear in
Hilbert space operators and operator algebras. These include proper
infiniteness, Murray von Neumann's classification into type I and type III
factors and the class of F{/o} lner C*-algebras that capture some aspects of
amenability. We will also mention how these notions reappear in the description
of certain mathematical aspects of quantum mechanics, quantum field theory and
the theory of superselection sectors. We also show that the algebra of the
canonical anti-commutation relations (CAR-algebra) is in the class of F{/o}
lner C*-algebras.Comment: 11 page
DIMBOA levels in hexaploid Brazilian wheat are not associated with antibiosis against the cereal aphids Rhopalosiphum padi and Sitobion avenae.
The objective of this study was to evaluate the natural levels of the plant defence compound DIMBOA in young leaves of eight hexaploid Brazilian wheat genotypes and the impact of the genotypes upon development of cereal aphids, Rhopalosiphum padi and Sitobion avenae. HPLC Analysis revealed that the DIMBOA levels varied from 5.376 (in BRS Guabiju) to 30.651 mmol/kgFW (in BRS Timbaúva) with two genotypes outperforming Solstice, a UK variety used as reference. Bioassays were conducted to evaluate the development and fecundity of both aphids when grown on the wheat genotypes. Although BRS Guabiju and BRS Timbaúva were among the genotypes showing the highest and lowest susceptibility respectively, against both aphids, no correlation could be found between DIMBOA levels and antibiosis effects. The cultivar BRS 327 that was among the genotypes showing lower intrinsic rate of population increase for the two aphid species. Elucidating the role of secondary metabolites in plant resistance to aphids and the characterisation of the genotypes that allowed reduced aphid development are important steps to achieve a better natural resistance in hexaploid Brazilian wheat
Extensive Spectroscopy and Photometry of the Type IIP Supernova 2013ej
We present extensive optical (, , and open CCD) and
near-infrared () photometry for the very nearby Type IIP SN ~2013ej
extending from +1 to +461 days after shock breakout, estimated to be MJD
. Substantial time series ultraviolet and optical spectroscopy
obtained from +8 to +135 days are also presented. Considering well-observed SNe
IIP from the literature, we derive bolometric calibrations from
and unfiltered measurements that potentially reach 2\% precision with a
color-dependent correction. We observe moderately strong Si II
as early as +8 days. The photospheric velocity () is
determined by modeling the spectra in the vicinity of Fe II
whenever observed, and interpolating at photometric epochs based on a
semianalytic method. This gives km s at +50
days. We also observe spectral homogeneity of ultraviolet spectra at +10--12
days for SNe IIP, while variations are evident a week after explosion. Using
the expanding photosphere method, from combined analysis of SN 2013ej and SN
2002ap, we estimate the distance to the host galaxy to be
Mpc, consistent with distance estimates from other methods. Photometric and
spectroscopic analysis during the plateau phase, which we estimated to be
days long, yields an explosion energy of
ergs, a final pre-explosion progenitor mass of ~M and a
radius of ~R. We observe a broken exponential profile beyond
+120 days, with a break point at + days. Measurements beyond this
break time yield a Ni mass of ~M.Comment: 29 pages, 23 figures, 15 tables, Published in The Astrophisical
Journa
High mortality associated with tapeworm parasitism in geladas (Theropithecus gelada) in the Simien Mountains National Park, Ethiopia
Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/138266/1/ajp22684.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/138266/2/ajp22684_am.pd
Aphid resistance in wheat varieties
As an environmentally compatible alternative to the use of conventional insecticides to control cereal aphids, we have investigated the possibility to exploit natural resistance to insect pests in wheat varieties. We have tested a wide range of hexaploid (Triticum aestivum), tetraploid (T. durum) and diploid (T. boeoticum and T. monococcum) wheat lines for resistance to the bird cherry oat aphid (Rhopalosiphum padi). Lines tested included Russian wheat aphid (Diuraphis noxia), greenbug (Schizaphis graminum), hessian fly (Mayetiola destructor) and orange wheat blossom midge (Sitodiplosis mosellana) resistant varieties. Antixenosis and antibiosis were determined in the settling and fecundity tests respectively. Since hydroxamic acids (Hx), including the most generally active, 2,4-dihidroxy-7-methoxy-1,4-benzoxazin-3-one (DIMBOA), are biosynthesised in many cereal plants and are implicated in resistance against insects, leaf tissue was analysed for Hx and the glucosides from which they are produced. The hexaploid varieties, which contained relatively low levels of the DIMBOA glucoside, did not deter aphid feeding or reduce nymph production significantly. Reduced settlement and nymph production were recorded on the diploid varieties, but they contained no detectable level of the glucoside or the toxic aglucone
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