139 research outputs found

    Running around the vicious circle: Cold War images in the contemporary Russian and American print media

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    The article was submitted on 09.03.2016.Π‘Ρ‚Π°Ρ‚ΡŒΡ посвящСна ΡΡ€Π°Π²Π½ΠΈΡ‚Π΅Π»ΡŒΠ½ΠΎ-стилистичСскому Π°Π½Π°Π»ΠΈΠ·Ρƒ политичСского Π½Π°Ρ€Ρ€Π°Ρ‚ΠΈΠ²Π° России ΠΈ БША Π²Ρ€Π΅ΠΌΠ΅Π½ Ρ…ΠΎΠ»ΠΎΠ΄Π½ΠΎΠΉ Π²ΠΎΠΉΠ½Ρ‹ 1950–1980 Π³Π³. ΠΈ 2015 Π³. Π’ качСствС ΠΌΠ΅Ρ‚ΠΎΠ΄ΠΎΠ»ΠΎΠ³ΠΈΠΈ исслСдования Π²Ρ‹Π±Ρ€Π°Π½Π° когнитивная тСория Π½Π°Ρ€Ρ€Π°Ρ‚ΠΈΠ²Π½ΠΎΠ³ΠΎ Π°Π½Π°Π»ΠΈΠ·Π°. ΠŸΠΎΠ»ΠΈΡ‚ΠΈΡ‡Π΅ΡΠΊΠΈΠΉ Π½Π°Ρ€Ρ€Π°Ρ‚ΠΈΠ² понимаСтся ΠΊΠ°ΠΊ Π΅Π΄ΠΈΠ½Ρ‹ΠΉ ΡΡŽΠΆΠ΅Ρ‚, ΠΎΠ±ΡŠΠ΅Π΄ΠΈΠ½ΡΡŽΡ‰ΠΈΠΉ мноТСство публицистичСских ΠΌΠ°Ρ‚Π΅Ρ€ΠΈΠ°Π»ΠΎΠ² Π½Π° протяТСнии ΠΎΠΏΡ€Π΅Π΄Π΅Π»Π΅Π½Π½ΠΎΠ³ΠΎ историчСского ΠΏΠ΅Ρ€ΠΈΠΎΠ΄Π° ΠΈ ΠΎΡ‚Ρ€Π°ΠΆΠ°ΡŽΡ‰ΠΈΠΉ Π³ΠΎΡΡƒΠ΄Π°Ρ€ΡΡ‚Π²Π΅Π½Π½ΡƒΡŽ идСологию с условным Π½Π°Π·Π²Π°Π½ΠΈΠ΅ΠΌ, постоянными пСрсонаТами, Π²Ρ‹ΠΏΠΎΠ»Π½ΡΡŽΡ‰ΠΈΠΌΠΈ ΠΏΠΎΠ»ΠΎΠΆΠΈΡ‚Π΅Π»ΡŒΠ½Ρ‹Π΅ Π»ΠΈΠ±ΠΎ ΠΎΡ‚Ρ€ΠΈΡ†Π°Ρ‚Π΅Π»ΡŒΠ½Ρ‹Π΅ Ρ€ΠΎΠ»ΠΈ, Π²Π΅Ρ€Π±Π°Π»ΡŒΠ½ΠΎ прСдставлСнный ΠΏΠΎΠ²Ρ‚ΠΎΡ€ΡΡŽΡ‰ΠΈΠΌΠΈΡΡ лСксичСскими Π΅Π΄ΠΈΠ½ΠΈΡ†Π°ΠΌΠΈ, стилистичСскими ΠΈ манипулятивными ΠΏΡ€ΠΈΠ΅ΠΌΠ°ΠΌΠΈ. УстановлСно, Ρ‡Ρ‚ΠΎ совСтский Π½Π°Ρ€Ρ€Π°Ρ‚ΠΈΠ² Π²Ρ€Π΅ΠΌΠ΅Π½ Ρ…ΠΎΠ»ΠΎΠ΄Π½ΠΎΠΉ Π²ΠΎΠΉΠ½Ρ‹ ΠΈΠΌΠ΅Π» Ρ‡Π΅Ρ‚ΠΊΠΎ прописанных ΠΎΡ‚Ρ€ΠΈΡ†Π°Ρ‚Π΅Π»ΡŒΠ½Ρ‹Ρ… Π³Π΅Ρ€ΠΎΠ΅Π²-капиталистов, Ρ€ΠΎΠ»ΡŒ ΠΈΡ… ΠΆΠ΅Ρ€Ρ‚Π² ΠΏΡ€ΠΈΠ½Π°Π΄Π»Π΅ΠΆΠ°Π»Π° простым ТитСлям капиталистичСских стран; ΠΏΠΎΠ»ΠΎΠΆΠΈΡ‚Π΅Π»ΡŒΠ½Ρ‹ΠΌΠΈ гСроями-спаситСлями выступали коммунисты. Он характСризовался ΠΎΠΏΡ€Π΅Π΄Π΅Π»Π΅Π½Π½Ρ‹ΠΌΠΈ спСцифичСскими Ρ‡Π΅Ρ€Ρ‚Π°ΠΌΠΈ: Ρ„ΠΎΡ€ΠΌΠΈΡ€ΠΎΠ²Π°Π½ΠΈΠ΅ Ρ‡Π΅Ρ‚ΠΊΠΎΠΉ ΠΎΠΏΠΏΠΎΠ·ΠΈΡ†ΠΈΠΈ «свой – Ρ‡ΡƒΠΆΠΎΠΉΒ»; Π²Ρ‹Π±ΠΎΡ€ΠΎΡ‡Π½ΠΎΠ΅ освСщСниС происходящих Π²ΠΎ Β«Π²Ρ€Π°ΠΆΠ΄Π΅Π±Π½ΠΎΠΉΒ» странС событий, тСндСнция ΠΊ ΠΈΡΠΊΠ»ΡŽΡ‡Π΅Π½ΠΈΡŽ всСго ΠΏΠΎΠ»ΠΎΠΆΠΈΡ‚Π΅Π»ΡŒΠ½ΠΎΠ³ΠΎ; ΠΎΠ΄Π½ΠΎΠ±ΠΎΠΊΠΎΠ΅, прСдвзятоС, сильно Π°Π½Π³Π°ΠΆΠΈΡ€ΠΎΠ²Π°Π½Π½ΠΎΠ΅ прСдставлСниС политичСских, экономичСских ΠΈ ΠΊΡƒΠ»ΡŒΡ‚ΡƒΡ€Π½Ρ‹Ρ… событий (высвСчиваниС ΠΏΠΎΠ»ΠΎΠΆΠΈΡ‚Π΅Π»ΡŒΠ½ΠΎΠ³ΠΎ Π² нашСй странС, ΠΏΡ€Π΅ΡƒΠ²Π΅Π»ΠΈΡ‡Π΅Π½ΠΈΠ΅ Ρ€Π΅Π·ΠΊΠΎ ΠΎΡ‚Ρ€ΠΈΡ†Π°Ρ‚Π΅Π»ΡŒΠ½ΠΎΠ³ΠΎ Π² Π·Π°ΠΏΠ°Π΄Π½Ρ‹Ρ… странах); ΡΠΌΠΎΡ†ΠΈΠΎΠ½Π°Π»ΡŒΠ½Π°Ρ Π½Π°ΠΏΠΎΠ»Π½Π΅Π½Π½ΠΎΡΡ‚ΡŒ ΠΎΠ±Ρ€Π°Π·Π° Β«Ρ‡ΡƒΠΆΠΎΠ³ΠΎΒ» благодаря ΡΠΎΠΎΡ‚Π²Π΅Ρ‚ΡΡ‚Π²ΡƒΡŽΡ‰ΠΈΠΌ языковым ΠΈ нСязыковым срСдствам; Ρ„ΠΎΡ€ΠΌΠΈΡ€ΠΎΠ²Π°Π½ΠΈΠ΅ стойкого ΠΎΡ‚Ρ€ΠΈΡ†Π°Ρ‚Π΅Π»ΡŒΠ½ΠΎΠ³ΠΎ ΠΎΠ±Ρ€Π°Π·Π° Β«Ρ‡ΡƒΠΆΠΎΠ³ΠΎΒ» Π·Π° счСт использования ΠΈΠ·Π½Π°Ρ‡Π°Π»ΡŒΠ½ΠΎ Π»ΠΎΠΆΠ½Ρ‹Ρ… ΠΏΡ€ΠΈΡ‡ΠΈΠ½Π½ΠΎ-слСдствСнных связСй (инсинуаций, Π»ΠΎΠΆΠ½Ρ‹Ρ… прСсуппозиций, ΠΏΡ€ΠΎΠ²ΠΎΠΊΠ°Ρ†ΠΈΠΉ); Ρ€Π΅Ρ„Ρ€Π΅ΠΉΠΌΠΈΠ½Π³ ΠΊΠΎΠ³Π½ΠΈΡ‚ΠΈΠ²Π½Ρ‹Ρ… прСдставлСний ΠΎ событиях Π² ΠΌΠΈΡ€Π΅, ΠΊΠΎΠ³Π΄Π° ΠΎΠ΄Π½ΠΎ ΠΈ Ρ‚ΠΎ ΠΆΠ΅ событиС трактуСтся ΠΏΠΎ-Ρ€Π°Π·Π½ΠΎΠΌΡƒ Π² силу ΡΡƒΡ‰Π΅ΡΡ‚Π²ΡƒΡŽΡ‰Π΅ΠΉ ΠΈΠ΄Π΅ΠΎΠ»ΠΎΠ³ΠΈΠΈ; объявлСниС собствСнных цСнностСй ΠΌΠΎΡ€Π°Π»ΡŒΠ½Ρ‹ΠΌΠΈ, Π° цСнностСй Β«Ρ‡ΡƒΠΆΠΎΠ³ΠΎΒ» бСзнравствСнными. Российский политичСский Π½Π°Ρ€Ρ€Π°Ρ‚ΠΈΠ² послСдних Π»Π΅Ρ‚ ΠΏΠΎΠ΄Π΄Π΅Ρ€ΠΆΠΈΠ²Π°Π΅Ρ‚ сцСнарий ΠΏΠΎΠ΄ условным Π½Π°Π·Π²Π°Π½ΠΈΠ΅ΠΌ «А Π½Π°ΠΌ всС Ρ€Π°Π²Π½ΠΎ – ΠΌΡ‹ Π½Π΅ боимся β€œΡΠ°Π½ΠΊΡ†ΠΈΠΎΠ½Π½Ρ‹Ρ… смотритСлСй”», Π² Ρ€ΠΎΠ»ΠΈ ΠΊΠΎΡ‚ΠΎΡ€Ρ‹Ρ… Π²Ρ‹ΡΡ‚ΡƒΠΏΠ°ΡŽΡ‚ ΠΏΡ€Π΅Π·ΠΈΠ΄Π΅Π½Ρ‚ БША ΠΈ Π»ΠΈΠ΄Π΅Ρ€Ρ‹ Π²Π΅Π΄ΡƒΡ‰ΠΈΡ… Π·Π°ΠΏΠ°Π΄Π½Ρ‹Ρ… стран – Β«Π±Π΅Π·Π²ΠΎΠ»ΡŒΠ½Ρ‹Π΅ ΠΌΠ°Ρ€ΠΈΠΎΠ½Π΅Ρ‚ΠΊΠΈ, бСзвластныС Ρ€ΡƒΠΊΠΎΠ²ΠΎΠ΄ΠΈΡ‚Π΅Π»ΠΈ своих государств». Π‘Ρ†Π΅Π½Π°Ρ€ΠΈΠΉ ΠΆΠ΅ Π½Π°Ρ€Ρ€Π°Ρ‚ΠΈΠ²Π° англоязычной Π·Π°ΠΏΠ°Π΄Π½ΠΎΠΉ прСссы: ΠŸΡƒΡ‚ΠΈΠ½ / Россия Π²Π΅Π΄Π΅Ρ‚ агрСссивныС дСйствия, Π²Ρ€Π°ΠΆΠ΄Π΅Π±Π΅Π½ БША, являСтся источником Π²ΠΎΠ΅Π½Π½Ρ‹Ρ… ΠΊΠΎΠ½Ρ„Π»ΠΈΠΊΡ‚ΠΎΠ², нСуступчив, нСпрСдсказуСм. БША Π½Π° словах ΠΎΡ‚ΡΡ‚Π°ΠΈΠ²Π°ΡŽΡ‚ Π΄Π΅ΠΌΠΎΠΊΡ€Π°Ρ‚ΠΈΡ‡Π½Ρ‹Π΅ цСнности, стрСмятся ΠΊ дСэскалации Π²ΠΎΠΎΡ€ΡƒΠΆΠ΅Π½Π½Ρ‹Ρ… противостояний, ΠΎΠΏΠ°ΡΠ°ΡŽΡ‚ΡΡ нСпрСдсказуСмости Π΄ΠΈΠΊΠΎΠΉ России / ΠŸΡƒΡ‚ΠΈΠ½Π°. Π’ российском Π½Π°Ρ€Ρ€Π°Ρ‚ΠΈΠ²Π΅ ΠΏΡ€Π΅ΠΎΠ±Π»Π°Π΄Π°ΡŽΡ‚ ΠΏΡ€ΠΈΠ΅ΠΌΡ‹ ΠΈΡ€ΠΎΠ½ΠΈΠΈ, сарказма, прямых насмСшСк ΠΈ использования обсцСнной лСксики Π² адрСс ΠΎΠΏΠΏΠΎΠ½Π΅Π½Ρ‚ΠΎΠ²; Π² англоязычном Π½Π°Ρ€Ρ€Π°Ρ‚ΠΈΠ²Π΅ Π΄ΠΎΠΌΠΈΠ½ΠΈΡ€ΡƒΠ΅Ρ‚ ΠΏΡ€ΠΈΠ΅ΠΌ запугивания, ΠΊΠΎΠ³Π΄Π° Β«Π²Ρ€Π°Π³Β» номинируСтся агрСссором, нСпрСдсказуСмым Π²Π°Ρ€Π²Π°Ρ€ΠΎΠΌ.The article presents a comparative stylistic analysis of the political narrative of Russia and the United States during two historical periods: the Cold War (1950–1980) and the year 2015. The authors choose the cognitive theory of narrative analysis as their research methodology. Political narrative is understood as a single story uniting multiple journalistic materials over a certain historical period of up to several decades, reflecting the state ideology with an arbitrary name, permanent positive or negative characters, and verbally presented via recurrent lexical units, stylistic and manipulation techniques. It is established that the Soviet narrative of the Cold War period had clearly defined villains – capitalists, while the role of victims belonged to ordinary citizens of the capitalist countries, and Communists were their saviors. The following specific features characterized the narrative: the formation of a clear opposition β€œus – them”; selective coverage of events occurring in the β€œhostile” countries, a tendency to the exclusion of anything positive; a one-sided, strongly biased view of the political, economic and cultural events (promoting the positive sides in this country and greatly exaggerating the negative ones in Western countries); an emotionally loaded image of β€œthem” created by employing appropriate linguistic and non-linguistic means; the formation of a persistent negative image of β€œthem” by the use of initially false causality (innuendo, false presuppositions, provocation); reframing cognitive representations of world events, when the same event is interpreted differently in different countries by the virtue of the existing ideology; declaration of one’s own values as moral, and β€œtheir” values as immoral. The Russian political narrative of last year supports a script called β€œWe don’t care – we are not afraid of β€˜the sanction masters’”, that is, the US President and leaders of European countries – β€œpuppets, powerless heads of their states”. The scenario of the narrative, which is now being created in the English-language media concerning relations with Russia, is that Putin/Russia is aggressive, hostile to the United States; it is a source of military conflicts, uncompromising and unpredictable. The US defends democratic values, seeks de-escalation of the existing armed confrontations, and fears the wild unpredictability of Putin/Russia. The Russian narrative is dominated by the methods of irony, sarcasm, ridicule, and direct use of obscene language against its opponents; in the English narrative intimidation dominates, when the notion of β€œthem” is referred to as an aggressor and unpredictable barbarian

    A nonperturbative model for the strong running coupling within potential approach

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    A nonperturbative model for the QCD invariant charge, which contains no low-energy unphysical singularities and possesses an elevated higher loop corrections stability, is developed in the framework of potential approach. The static quark-antiquark potential is constructed by making use of the proposed model for the strong running coupling. The obtained result coincides with the perturbative potential at small distances and agrees with relevant lattice simulation data in the nonperturbative physically-relevant region. The developed model yields a reasonable value of the QCD scale parameter, which is consistent with its previous estimations obtained within potential approach.Comment: 14 pages, 4 figure

    INFORMATION CULTURE AND INFORMATION SAFETY OF SCHOOLCHILDREN

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    Introduction. The article is devoted to the problem of interaction between schoolchildren and possible informational risks transmitted on the Internet. Considering the lack of external filters on the way of harmful information streams, it is actually necessary to develop information culture of schoolchildren, their abilities to sensibly and critically interpret the information on the Internet, and choice of adequate behaviour models surfing the Web.Β The aim of the present research is to analyze the state of informational safety of schoolchildren while using the Internet; gaining an understanding of the role of external restrictions and opportunities of intrapersonal filtration of the harmful Internet content depending on children age. Methodology and research methods. The methodology of the research is based on modern methods aimed to consider the problem of personal socialization in modern information society. Thus, the Internet Initiatives Development Fund (IIDF) questionnaire let the authors define the level of awareness of recipients on the problem under consideration. Results and scientific novelty. The theoretical analysis helped the authors predict the correlation of basic methods in order to guarantee personal safety of schoolchildren taking into account the process of maturity as well as the decrease of external filters that may stop harmful content. Empirical part of the research has enabled to reveal decrease in external control of staying of a child in network in the process of growing up against the background of restrictive attitudes prevalence among teachers and parents. Therefore, the research supposed to improve information culture of schoolchildren from the earliest ages encouraging them to sensibly and correctly interpret the information on the Internet. Practical significance. The practical recommendations to parents and teachers in order to improve informational personal safety of schoolchildren are proposed. The relevancy of information and communication competence increase among teachers and parents is emphasized.Β Π’Π²Π΅Π΄Π΅Π½ΠΈΠ΅. Π‘Ρ‚Π°Ρ‚ΡŒΡ посвящСна ΠΏΡ€ΠΎΠ±Π»Π΅ΠΌΠ΅ противостояния ΠΈΠ½Ρ„ΠΎΡ€ΠΌΠ°Ρ†ΠΈΠΎΠ½Π½Ρ‹ΠΌ рискам, транслируСмым Ρ‡Π΅Ρ€Π΅Π· ΡΠ΅Ρ‚ΡŒ Π˜Π½Ρ‚Π΅Ρ€Π½Π΅Ρ‚. Π’ ситуации отсутствия Π²Π½Π΅ΡˆΠ½ΠΈΡ… ΠΏΡ€Π΅Π³Ρ€Π°Π΄ Π½Π° ΠΏΡƒΡ‚ΠΈ врСдоносных ΠΈΠ½Ρ„ΠΎΡ€ΠΌΠ°Ρ†ΠΈΠΎΠ½Π½Ρ‹Ρ… ΠΏΠΎΡ‚ΠΎΠΊΠΎΠ² актуализируСтся Π½Π΅ΠΎΠ±Ρ…ΠΎΠ΄ΠΈΠΌΠΎΡΡ‚ΡŒ формирования ΠΈΠ½Ρ„ΠΎΡ€ΠΌΠ°Ρ†ΠΈΠΎΠ½Π½ΠΎΠΉ ΠΊΡƒΠ»ΡŒΡ‚ΡƒΡ€Ρ‹ школьников; ΠΈΡ… способности осмыслСнного восприятия ΠΈ критичСской ΠΎΡ†Π΅Π½ΠΊΠΈ ΠΈΠ½Ρ„ΠΎΡ€ΠΌΠ°Ρ†ΠΈΠΈ, ΠΏΠΎΡ‡Π΅Ρ€ΠΏΠ½ΡƒΡ‚ΠΎΠΉ Π² сСти; Π²Ρ‹Π±ΠΎΡ€Π° Π°Π΄Π΅ΠΊΠ²Π°Ρ‚Π½Ρ‹Ρ… повСдСнчСских ΠΌΠΎΠ΄Π΅Π»Π΅ΠΉ Π²ΠΎ врСмя Π²Ρ‹Ρ…ΠΎΠ΄Π° Π² ΠΈΠ½Ρ‚Π΅Ρ€Π½Π΅Ρ‚-пространство. ЦСль ΠΏΡ€Π΅Π΄Π»Π°Π³Π°Π΅ΠΌΠΎΠ³ΠΎ вниманию исслСдования – ΠΈΠ·ΡƒΡ‡Π΅Π½ΠΈΠ΅ состояния ΠΈΠ½Ρ„ΠΎΡ€ΠΌΠ°Ρ†ΠΈΠΎΠ½Π½ΠΎΠΉ бСзопасности школьников, выяснСниС Ρ€ΠΎΠ»ΠΈ Π²Π½Π΅ΡˆΠ½ΠΈΡ… ΠΎΠ³Ρ€Π°Π½ΠΈΡ‡Π΅Π½ΠΈΠΉ ΠΈ возмоТностСй внутриличностной Ρ„ΠΈΠ»ΡŒΡ‚Ρ€Π°Ρ†ΠΈΠΈ врСдоносного ΠΈΠ½Ρ‚Π΅Ρ€Π½Π΅Ρ‚-ΠΊΠΎΠ½Ρ‚Π΅Π½Ρ‚Π° Π² зависимости ΠΎΡ‚ возраста Π΄Π΅Ρ‚Π΅ΠΉ. ΠœΠ΅Ρ‚ΠΎΠ΄ΠΎΠ»ΠΎΠ³ΠΈΡ ΠΈ ΠΌΠ΅Ρ‚ΠΎΠ΄ΠΈΠΊΠΈ. ΠœΠ΅Ρ‚ΠΎΠ΄ΠΎΠ»ΠΎΠ³ΠΈΡ исслСдования базируСтся Π½Π° соврСмСнных ΠΏΠΎΠ΄Ρ…ΠΎΠ΄Π°Ρ… ΠΊ ΠΏΡ€ΠΎΠ±Π»Π΅ΠΌΠ΅ социализации личности. Для опрСдСлСния стСпСни освСдомлСнности учащихся, ΠΈΡ… Ρ€ΠΎΠ΄ΠΈΡ‚Π΅Π»Π΅ΠΉ ΠΈ ΠΏΠ΅Π΄Π°Π³ΠΎΠ³ΠΎΠ² Π² области ΠΈΠ½Ρ„ΠΎΡ€ΠΌΠ°Ρ†ΠΈΠΎΠ½Π½ΠΎΠΉ бСзопасности использовался Π°Π΄Π°ΠΏΡ‚ΠΈΡ€ΠΎΠ²Π°Π½Π½Ρ‹ΠΉ Π²Π°Ρ€ΠΈΠ°Π½Ρ‚ опросника Π€ΠΎΠ½Π΄Π° развития Π˜Π½Ρ‚Π΅Ρ€Π½Π΅Ρ‚. Π Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚Ρ‹ ΠΈ научная Π½ΠΎΠ²ΠΈΠ·Π½Π°. ВСорСтичСский Π°Π½Π°Π»ΠΈΠ· ΠΏΠΎΠ·Π²ΠΎΠ»ΠΈΠ» ΡƒΡΡ‚Π°Π½ΠΎΠ²ΠΈΡ‚ΡŒ ΡΠΎΠΎΡ‚Π½ΠΎΡˆΠ΅Π½ΠΈΠ΅ основных – Π·Π°ΠΏΡ€Π΅Ρ‚ΠΈΡ‚Π΅Π»ΡŒΠ½ΠΎ-ΠΎΠ³Ρ€Π°Π½ΠΈΡ‡ΠΈΡ‚Π΅Π»ΡŒΠ½ΠΎΠ³ΠΎ ΠΈ личностно-Ρ€Π°Π·Π²ΠΈΠ²Π°ΡŽΡ‰Π΅Π³ΠΎ – ΠΏΠΎΠ΄Ρ…ΠΎΠ΄ΠΎΠ² ΠΊ ΠΎΠ±Π΅ΡΠΏΠ΅Ρ‡Π΅Π½ΠΈΡŽ ΠΈΠ½Ρ„ΠΎΡ€ΠΌΠ°Ρ†ΠΈΠΎΠ½Π½ΠΎΠΉ бСзопасности школьников с ΡƒΡ‡Π΅Ρ‚ΠΎΠΌ закономСрностСй ΠΈΡ… взрослСния. ЭмпиричСская Ρ‡Π°ΡΡ‚ΡŒ исслСдования ΠΏΠΎΠΊΠ°Π·Π°Π»Π° сниТСниС внСшнСго контроля прСбывания Ρ€Π΅Π±Π΅Π½ΠΊΠ° Π² сСти ΠΏΠΎ ΠΌΠ΅Ρ€Π΅ Π΅Π³ΠΎ взрослСния Π½Π° Ρ„ΠΎΠ½Π΅ прСобладания ΠΎΠ³Ρ€Π°Π½ΠΈΡ‡ΠΈΡ‚Π΅Π»ΡŒΠ½Ρ‹Ρ… установок Ρƒ ΠΏΠ΅Π΄Π°Π³ΠΎΠ³ΠΎΠ² ΠΈ Ρ€ΠΎΠ΄ΠΈΡ‚Π΅Π»Π΅ΠΉ. Π’ связи с ΠΎΠ±ΡŠΠ΅ΠΊΡ‚ΠΈΠ²Π½Ρ‹ΠΌΠΈ ΠΏΡ€ΠΈΡ‡ΠΈΠ½Π°ΠΌΠΈ ослаблСния Π²Π½Π΅ΡˆΠ½ΠΈΡ… ΠΎΠ³Ρ€Π°Π½ΠΈΡ‡ΠΈΡ‚Π΅Π»ΡŒΠ½Ρ‹Ρ… Ρ„ΠΈΠ»ΡŒΡ‚Ρ€ΠΎΠ² Π½Π° ΠΏΡƒΡ‚ΠΈ врСдоносного ΠΊΠΎΠ½Ρ‚Π΅Π½Ρ‚Π° ΠΏΠΎ ΠΌΠ΅Ρ€Π΅ Ρ€Π°ΡΡˆΠΈΡ€Π΅Π½ΠΈΡ ΡΠΎΡ†ΠΈΠ°Π»ΡŒΠ½ΠΎΠΉ активности Ρ€Π°Π·Π²ΠΈΠ²Π°ΡŽΡ‰Π΅ΠΉΡΡ личности обоснована Π½Π΅ΠΎΠ±Ρ…ΠΎΠ΄ΠΈΠΌΠΎΡΡ‚ΡŒ личностно-Ρ€Π°Π·Π²ΠΈΠ²Π°ΡŽΡ‰Π΅Π³ΠΎ ΠΏΠΎΠ΄Ρ…ΠΎΠ΄Π° ΠΊ Ρ„ΠΎΡ€ΠΌΠΈΡ€ΠΎΠ²Π°Π½ΠΈΡŽ ΠΈΠ½Ρ„ΠΎΡ€ΠΌΠ°Ρ†ΠΈΠΎΠ½Π½ΠΎΠΉ ΠΊΡƒΠ»ΡŒΡ‚ΡƒΡ€Ρ‹ Π΄Π΅Ρ‚Π΅ΠΉ начиная с Ρ€Π°Π½Π½Π΅Π³ΠΎ возраста. ΠŸΡ€Π°ΠΊΡ‚ΠΈΡ‡Π΅ΡΠΊΠ°Ρ Π·Π½Π°Ρ‡ΠΈΠΌΠΎΡΡ‚ΡŒ. Π‘Ρ„ΠΎΡ€ΠΌΡƒΠ»ΠΈΡ€ΠΎΠ²Π°Π½Ρ‹ Ρ€Π΅ΠΊΠΎΠΌΠ΅Π½Π΄Π°Ρ†ΠΈΠΈ ΠΏΠΎ Ρ€Π΅Π°Π»ΠΈΠ·Π°Ρ†ΠΈΠΈ ΠΌΠ΅Ρ€ ΠΈΠ½Ρ„ΠΎΡ€ΠΌΠ°Ρ†ΠΈΠΎΠ½Π½ΠΎΠΉ бСзопасности школьников Π½Π° Ρ€Π°Π·Π½Ρ‹Ρ… ступСнях обучСния. ΠŸΠΎΠ΄Ρ‡Π΅Ρ€ΠΊΠ½ΡƒΡ‚Π° Π½Π΅ΠΎΠ±Ρ…ΠΎΠ΄ΠΈΠΌΠΎΡΡ‚ΡŒ ΠΏΠΎΠ²Ρ‹ΡˆΠ΅Π½ΠΈΡ ΠΈΠ½Ρ„ΠΎΡ€ΠΌΠ°Ρ†ΠΈΠΎΠ½Π½ΠΎ-ΠΊΠΎΠΌΠΌΡƒΠ½ΠΈΠΊΠ°Ρ†ΠΈΠΎΠ½Π½ΠΎΠΉ компСтСнтности ΠΏΠ΅Π΄Π°Π³ΠΎΠ³ΠΎΠ² ΠΈ Ρ€ΠΎΠ΄ΠΈΡ‚Π΅Π»Π΅ΠΉ учащихся.

    Abundance analysis of two late A-type stars HD 32115 and HD 37594

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    We have performed abundance analysis of two slowly rotating, late A-type stars, HD 32115 (HR 1613) and HD 37594 (HR 1940), based on obtained echelle spectra covering the spectral range 4000-9850 AAngstrom. These spectra allowed us to identify an extensive line list for 31 chemical elements, the most complete to date for A-type stars. Two approaches to abundance analysis were used, namely a ``manual'' (interactive) and a semi-automatic procedure for comparison of synthetic and observed spectra and equivalent widths. For some elements non-LTE (NLTE) calculations were carried out and the corresponding corrections have been applied. The abundance pattern of HD 32115 was found to be very close to the solar abundance pattern, and thus may be used as an abundance standard for chemical composition studies in middle and late A stars. Further, its H-alpha line profile shows no core-to-wing anomaly like that found for cool Ap stars and therefore also may be used as a standard in comparative studies of the atmospheric structures of cool, slowly rotating Ap stars. HD 37594 shows a metal deficiency at the level of -0.3 dex for most elements and triangle-like cores of spectral lines. This star most probably belongs to the Delta Scuti group.Comment: 10 pages, 4 figure

    1,3-Disubstituted p-tert-butylcalix[4]arenes as cholinesterase inhibitors

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    The inhibitory effect of 1,3-substituted p-tert-butylcalix[4]arenes on butyrylcholinesterase from horse serum has been discovered and kinetically investigated with photometric microassay techniques. The interaction of calix[4]arene with the enzyme is described in accordance with the formal kinetics of competitive reversible inhibition. The inhibition constants calculated depend on the substituent in the lower rim of the calix[4]arene and vary in the range of (5-110) Γ— 10-6 M. The proposed mechanism of inhibition involves the cooperative interaction of indophenyl acetate used as a substrate, calix[4]arene and the enzyme without any covalent or electrostatic binding of the functional groups in the active site of cholinesterase. This results in the coordination of the calixarene on the enzyme surface in the proximity of the enzyme active site. Such interaction prevents the substrate from entering the enzyme active site

    Selection of a SARS-CoV-2 antibody quantification method and development of an antibody reference standard for ELISA to test immunoglobulin preparations

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    TheΒ development of COVID-globulin, aΒ COVID-19-specific human immunoglobulin preparation, involved choosing aΒ method toΒ quantify antibodies to SARS-CoV-2. Antibody titre determination by virus neutralisation (VN) is labour-intensive and unsuitable for large-scale application. ToΒ enable routine testing, it was necessary toΒ develop aΒ less demanding method; theΒ enzyme-linked immunosorbent assay (ELISA) was theΒ most appropriate of solutions. TheΒ lack of international and industry reference standards (RS) prompted theΒ preparation and certification of anΒ RS for COVID-globulin potency control.TheΒ aim of theΒ study was toΒ examine theΒ possibility of substituting ELISA for VN and to develop anΒ RS for SARS-CoV-2 antibody quantification in immunoglobulin preparations.Materials and methods: theΒ authors used commercial ELISA kits by several manufacturers, COVID-globulin by Microgen (48 batches), and human plasma samples from multiple sources (1499 samples). TheΒ tests were performed by VN, ELISA, and chemiluminescent microparticle immunoassay.Results: theΒ authors validated anΒ ELISA method for SARS-CoV-2 antibody quantification with theΒ selected reagent kits by theΒ National Medical Research Center for Hematology (NMRC for Hematology) and Euroimmun AG. TheΒ authors demonstrated theΒ possibility of using ELISA instead of VN (with aΒ correlation coefficient of more than 0.9). They developed and characterised anΒ in-houseΒ RS for SARS-CoV-2 antibody content in human immunoglobulin preparations. TheΒ RS was certified in newly introduced anti-COVID units (ACU) and in international binding antibody units (BAU) using the World Health Organisation (WHO) international reference panel (NIBSC code: 20/268). TheΒ RS's potency was measured in terms of its neutralising activity in ACU (320 ACU/mL) and BAU (2234.8 BAU/mL). TheΒ authors established theΒ relationship between ACU and BAU units. For theΒ selected ELISA reagent kits, theΒ conversion factors were 6.4 (NMRC for Hematology) and 7.0 (Euroimmun AG).Conclusions: theΒ ELISA method for SARS-CoV-2 antibody quantification and theΒ RS for SARS-CoV-2 antibody content can be applied toΒ determine theΒ potency of human anti-COVID-19 immunoglobulins

    Discrimination of apple juice and herbal liqueur brands with solid-state electrodes covered with polyaniline and thiacalixarenes

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    Solid-contact ion-selective electrodes based on glassy carbon electrode covered with electropolymerized polyaniline and tetrasubstituted thiacalix[4]arene ionophores with hexyl and o-pyridylamido functional groups at the lower rim have been developed and examined in the discrimination of the brands of apple juices and herbal liqueurs. For this purpose, the liquids tested were diluted and spiked with a constant amount of Fe3+ ions. The variation of the signal toward Fe3+ ions was achieved due to their involvement in the reactions with the organic ligands and the antioxidants present. As was shown, the combination of the three electrodes with various receptors makes it possible to predict the brand of apple juices and herbal liqueurs using linear discriminant analysis in 95-100% cases. The discrimination procedure makes it possible to discriminate liquids within 20 min. Besides, the electrodes developed make it possible to detect individual antioxidants (ascorbic, malic, oxalic acids, hydroquinone, and quercetin) in the range from 5.0 Γ— 10-6 to 1.0 Γ— 10-2 M in direct potentiometric measurements and redox titration. Β© 2010 Elsevier B.V. All rights reserved

    ΠžΠ‘ΠžΠ‘ΠΠžΠ’ΠΠΠ˜Π• Π˜Π‘Π‘Π›Π•Π”ΠžΠ’ΠΠΠ˜Π― ПО ΠžΠŸΠ’Π˜ΠœΠ˜Π—ΠΠ¦Π˜Π˜ Π‘Π˜Π‘Π’Π•ΠœΠ« ΠžΠšΠΠ—ΠΠΠ˜Π― Π₯Π˜Π Π£Π Π“Π˜Π§Π•Π‘ΠšΠžΠ™ Π‘Π’ΠžΠœΠΠ’ΠžΠ›ΠžΠ“Π˜Π§Π•Π‘ΠšΠžΠ™ ПОМОЩИ ΠŸΠΠ¦Π˜Π•ΠΠ’ΠΠœ Π‘ Π’Π˜Π§-Π˜ΠΠ€Π•ΠšΠ¦Π˜Π•Π™. ΠΠΠΠ›Π˜Π’Π˜Π§Π•Π‘ΠšΠ˜Π™ ΠžΠ‘Π—ΠžΠ  Π›Π˜Π’Π•Π ΠΠ’Π£Π Π«

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    The article presents an analysis of the Russian and foreign specialized literature on the problem of dental rehabilitation of patients with HIV infection. It has been revealed that the structure and prevalence of dental surgical pathology in HIV infection has not been studied to date, the indices of the need for treatment of diseases of the dental profile have not been determined. Unsatisfactory access to qualified dental care has been identified, including due to discrimination and stigmatization by health professionals regarding both the disease itself and patients with HIV infection. The urgency of improving the system of rendering surgical dental care to HIV-infected with the aim of ensuring the maximum achievable level of health is substantiated. The data of the presented analytical review represent an important theoretical basis for the development of new tactical approaches to the implementation of the strategic direction of dental implant treatment of people living with HIV to expand access to this medical service.Π’ ΡΡ‚Π°Ρ‚ΡŒΠ΅ прСдставлСн Π°Π½Π°Π»ΠΈΠ· Π΄Π°Π½Π½Ρ‹Ρ… отСчСствСнной ΠΈ Π·Π°Ρ€ΡƒΠ±Π΅ΠΆΠ½ΠΎΠΉ ΡΠΏΠ΅Ρ†ΠΈΠ°Π»ΡŒΠ½ΠΎΠΉ Π»ΠΈΡ‚Π΅Ρ€Π°Ρ‚ΡƒΡ€Ρ‹ ΠΏΠΎ ΠΏΡ€ΠΎΠ±Π»Π΅ΠΌΠ΅ стоматологичСской Ρ€Π΅Π°Π±ΠΈΠ»ΠΈΡ‚Π°Ρ†ΠΈΠΈ ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠ² с Π’Π˜Π§ΠΈΠ½Ρ„Π΅ΠΊΡ†ΠΈΠ΅ΠΉ. ВыявлСно, Ρ‡Ρ‚ΠΎ Π΄ΠΎ настоящСго Π²Ρ€Π΅ΠΌΠ΅Π½ΠΈ Π½Π΅ ΠΈΠ·ΡƒΡ‡Π΅Π½Π° структура ΠΈ Ρ€Π°ΡΠΏΡ€ΠΎΡΡ‚Ρ€Π°Π½Ρ‘Π½Π½ΠΎΡΡ‚ΡŒ стоматологичСской хирургичСской ΠΏΠ°Ρ‚ΠΎΠ»ΠΎΠ³ΠΈΠΈ ΠΏΡ€ΠΈ Π’Π˜Π§-ΠΈΠ½Ρ„Π΅ΠΊΡ†ΠΈΠΈ, Π½Π΅ ΠΎΠΏΡ€Π΅Π΄Π΅Π»Π΅Π½Ρ‹ ΠΏΠΎΠΊΠ°Π·Π°Ρ‚Π΅Π»ΠΈ нуТдаСмости Π² Π»Π΅Ρ‡Π΅Π½ΠΈΠΈ Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΠΉ стоматологичСского профиля. ВыявлСн Π½Π΅ΡƒΠ΄ΠΎΠ²Π»Π΅Ρ‚Π²ΠΎΡ€ΠΈΡ‚Π΅Π»ΡŒΠ½Ρ‹ΠΉ доступ ΠΊ ΠΊΠ²Π°Π»ΠΈΡ„ΠΈΡ†ΠΈΡ€ΠΎΠ²Π°Π½Π½ΠΎΠΉ стоматологичСской ΠΏΠΎΠΌΠΎΡ‰ΠΈ, Π² Ρ‚ΠΎΠΌ числС ΠΈΠ·-Π·Π° дискриминации ΠΈ стигматизации со стороны мСдицинских Ρ€Π°Π±ΠΎΡ‚Π½ΠΈΠΊΠΎΠ² Π² ΠΎΡ‚Π½ΠΎΡˆΠ΅Π½ΠΈΠΈ ΠΊΠ°ΠΊ самого заболСвания, Ρ‚Π°ΠΊ ΠΈ Π±ΠΎΠ»ΡŒΠ½Ρ‹Ρ… Π’Π˜Π§-ΠΈΠ½Ρ„Π΅ΠΊΡ†ΠΈΠ΅ΠΉ. Обоснована Π°ΠΊΡ‚ΡƒΠ°Π»ΡŒΠ½ΠΎΡΡ‚ΡŒ ΡΠΎΠ²Π΅Ρ€ΡˆΠ΅Π½ΡΡ‚Π²ΠΎΠ²Π°Π½ΠΈΡ систСмы оказания хирургичСской стоматологичСской ΠΏΠΎΠΌΠΎΡ‰ΠΈ Π’Π˜Π§-ΠΈΠ½Ρ„ΠΈΡ†ΠΈΡ€ΠΎΠ²Π°Π½Π½Ρ‹ΠΌ с Ρ†Π΅Π»ΡŒΡŽ обСспСчСния максимально достиТимого уровня Π·Π΄ΠΎΡ€ΠΎΠ²ΡŒΡ. Π”Π°Π½Π½Ρ‹Π΅ этого аналитичСского ΠΎΠ±Π·ΠΎΡ€Π° ΠΏΡ€Π΅Π΄ΡΡ‚Π°Π²Π»ΡΡŽΡ‚ Π²Π°ΠΆΠ½ΡƒΡŽ Ρ‚Π΅ΠΎΡ€Π΅Ρ‚ΠΈΡ‡Π΅ΡΠΊΡƒΡŽ основу для Ρ€Π°Π·Ρ€Π°Π±ΠΎΡ‚ΠΊΠΈ Π½ΠΎΠ²Ρ‹Ρ… тактичСских ΠΏΠΎΠ΄Ρ…ΠΎΠ΄ΠΎΠ² ΠΊ Ρ€Π΅Π°Π»ΠΈΠ·Π°Ρ†ΠΈΠΈ стратСгичСского направлСния стоматологичСского имплантологичСского лСчСния людСй, ΠΆΠΈΠ²ΡƒΡ‰ΠΈΡ… с Π’Π˜Π§, для Ρ€Π°ΡΡˆΠΈΡ€Π΅Π½ΠΈΡ доступа ΠΊ Π΄Π°Π½Π½ΠΎΠΉ мСдицинской услугС

    ΠžΡ†Π΅Π½ΠΊΠ° качСства трСсты ΠΏΡ€ΠΈ Ρ€Π°Π·Π΄Π΅Π»ΡŒΠ½ΠΎΠΉ Ρ‚Π΅Ρ…Π½ΠΎΠ»ΠΎΠ³ΠΈΠΈ ΡƒΠ±ΠΎΡ€ΠΊΠΈ льна-Π΄ΠΎΠ»Π³ΡƒΠ½Ρ†Π°

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    The paper explores the technological aspects and methods involved in the preparation of flax straw within the framework of separate fiber flax harvesting technology. This particular technology allows for the prolonged maturation of seeds in the field. The study demonstrates that during the process of seasoning flax straw in the form of unprocessed stem ribbons, the seeds within the capsules undergo natural drying and ripening. This approach enables a reduction in fuel consumption compared to the traditional scheme while obtaining high-quality fiber and seeds suitable for sowing. (Research purpose) The objective of this study is to assess the quality of raw flax during the stage of straw flax preparation. (Materials and methods) The study investigates the processes and technical units involved in fiber flax harvesting, adhering to regulatory guidelines during the stages of stem pulling, seasoning, turning, picking, and processing are thoroughly examined. (Results and discussion) The research results have revealed the indicators for biological productivity of straw and seeds during the process of straw flax preparation. Under different seeding rates, the yield of straw flax ranges from 23.1 to 24.8 centners per hectare during a 14-day seasoning period and from 20.8 to 22.2 centners per hectare on the 21st day. These findings demonstrate that the average yield under various harvesting conditions is 20-30 centners per hectare. The flaxseed yield, ranging from 2.9 to 4.1 centners per hectare at different maturation periods, can be considered satisfactory. Furthermore, it was observed that the elongation of the flax ribbon increases after turning, compared to its initial state, when the combine speed is 5.3 and 7.8 kilometers per hour, remaining within the acceptable limits. However, at a speed of 9.6 kilometers per hour, there was a violation of agrotechnical requirements. (Conclusions) The separate harvesting of flax has proven to be effective during a three-week period of raw flax seasoning. It is important to note that when turning unprocessed flax ribbons, the working speed should not exceed 9 kilometers per hour.РассмотрСли тСхнологичСскиС аспСкты ΠΈ ΠΏΡ€ΠΈΠ΅ΠΌΡ‹ приготовлСния льняной трСсты ΠΏΡ€ΠΈ Ρ€Π°Π·Π΄Π΅Π»ΡŒΠ½ΠΎΠΌ способС ΡƒΠ±ΠΎΡ€ΠΊΠΈ льна-Π΄ΠΎΠ»Π³ΡƒΠ½Ρ†Π°. Данная тСхнология позволяСт ΠΏΡ€ΠΎΠ΄Π»ΠΈΡ‚ΡŒ созрСваниС сСмян Π½Π° ΠΊΠΎΡ€Π½ΡŽ. Показали, Ρ‡Ρ‚ΠΎ Π·Π° врСмя Π²Ρ‹Π»Π΅ΠΆΠΊΠΈ Π»ΡŒΠ½ΠΎΡΠΎΠ»ΠΎΠΌΡ‹ Π² Π²ΠΈΠ΄Π΅ Π»Π΅Π½Ρ‚ нСочСсанных стСблСй сСмСна Π² ΠΊΠΎΡ€ΠΎΠ±ΠΎΡ‡ΠΊΠ°Ρ… ΠΏΠΎΠ΄ΡΡ‹Ρ…Π°ΡŽΡ‚ ΠΈ Π΄ΠΎΠ·Ρ€Π΅Π²Π°ΡŽΡ‚ СстСствСнным ΠΎΠ±Ρ€Π°Π·ΠΎΠΌ. Π­Ρ‚ΠΎ позволяСт ΡΠ½ΠΈΠ·ΠΈΡ‚ΡŒ расход Ρ‚ΠΎΠΏΠ»ΠΈΠ²Π½Ρ‹Ρ… рСсурсов Π² сравнСнии с Ρ‚Ρ€Π°Π΄ΠΈΡ†ΠΈΠΎΠ½Π½ΠΎΠΉ схСмой, ΠΏΠΎΠ»ΡƒΡ‡ΠΈΡ‚ΡŒ качСствСнноС Π²ΠΎΠ»ΠΎΠΊΠ½ΠΎ ΠΈ ΠΏΡ€ΠΈΠ³ΠΎΠ΄Π½Ρ‹Π΅ для посСва сСмСна. (ЦСль исслСдования) ΠžΡ†Π΅Π½ΠΈΡ‚ΡŒ качСство Π»ΡŒΠ½ΠΎΡΡ‹Ρ€ΡŒΡ Π½Π° этапС приготовлСния трСсты. (ΠœΠ°Ρ‚Π΅Ρ€ΠΈΠ°Π»Ρ‹ ΠΈ ΠΌΠ΅Ρ‚ΠΎΠ΄Ρ‹) Π˜Π·ΡƒΡ‡ΠΈΠ»ΠΈ процСссы ΠΈ тСхничСскиС срСдства ΠΏΡ€ΠΈ ΡƒΠ±ΠΎΡ€ΠΊΠ΅ льна-Π΄ΠΎΠ»Π³ΡƒΠ½Ρ†Π° Π² соотвСтствии с Π½ΠΎΡ€ΠΌΠ°Ρ‚ΠΈΠ²Π½ΠΎΠΉ Π΄ΠΎΠΊΡƒΠΌΠ΅Π½Ρ‚Π°Ρ†ΠΈΠ΅ΠΉ Π½Π° этапах выдСргивания, Π²Ρ‹Π»Π΅ΠΆΠΊΠΈ, оборачивания, ΠΏΠΎΠ΄Π±ΠΎΡ€Π° ΠΈ очСсывания стСблСй. (Π Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚Ρ‹ ΠΈ обсуТдСниС) ΠžΠΏΡ€Π΅Π΄Π΅Π»Π΅Π½Ρ‹ ΠΏΠΎΠΊΠ°Π·Π°Ρ‚Π΅Π»ΠΈ биологичСской уроТайности трСсты ΠΈ сСмян Π² процСссС приготовлСния Π»ΡŒΠ½ΠΎΡ‚Ρ€Π΅ΡΡ‚Ρ‹. ΠŸΡ€ΠΈ Ρ€Π°Π·Π»ΠΈΡ‡Π½ΠΎΠΉ Π½ΠΎΡ€ΠΌΠ΅ высСва сСмян ΡƒΡ€ΠΎΠΆΠ°ΠΉΠ½ΠΎΡΡ‚ΡŒ трСсты достигала 23,1-24,8 Ρ†Π΅Π½Ρ‚Π½Π΅Ρ€Π° Π½Π° 1 Π³Π΅ΠΊΡ‚Π°Ρ€ ΠΈ срокС Π²Ρ‹Π»Π΅ΠΆΠΊΠΈ 14 Π΄Π½Π΅ΠΉ, Π° Ρ‚Π°ΠΊΠΆΠ΅ 20,8-22,2 Ρ†Π΅Π½Ρ‚Π½Π΅Ρ€Π° Π½Π° 1 Π³Π΅ΠΊΡ‚Π°Ρ€ Π½Π° 21-ΠΉ дСнь. Богласно исслСдованиям срСдняя ΡƒΡ€ΠΎΠΆΠ°ΠΉΠ½ΠΎΡΡ‚ΡŒ ΠΏΡ€ΠΈ Ρ€Π°Π·Π»ΠΈΡ‡Π½Ρ‹Ρ… условиях ΡƒΠ±ΠΎΡ€ΠΊΠΈ составляСт 20-30 Ρ†Π΅Π½Ρ‚Π½Π΅Ρ€ΠΎΠ² с 1 Π³Π΅ΠΊΡ‚Π°Ρ€Π°. Π£Ρ€ΠΎΠΆΠ°ΠΉΠ½ΠΎΡΡ‚ΡŒ льносСмян ΠΎΡ‚ 2,9 Π΄ΠΎ 4,1 Ρ†Π΅Π½Ρ‚Π½Π΅Ρ€Π° с 1 Π³Π΅ΠΊΡ‚Π°Ρ€Π° ΠΏΡ€ΠΈ Ρ€Π°Π·Π½Ρ‹Ρ… сроках Π²Ρ‹Π»Π΅ΠΆΠΊΠΈ ΠΌΠΎΠΆΠ½ΠΎ ΡΡ‡ΠΈΡ‚Π°Ρ‚ΡŒ Π²ΠΏΠΎΠ»Π½Π΅ допустимой. Π Π°ΡΡ‚ΡΠ½ΡƒΡ‚ΠΎΡΡ‚ΡŒ Π»Π΅Π½Ρ‚Ρ‹ послС оборачивания возрастала ΠΏΠΎ ΡΡ€Π°Π²Π½Π΅Π½ΠΈΡŽ с исходной ΠΏΡ€ΠΈ скорости ΠΊΠΎΠΌΠ±Π°ΠΉΠ½Π° 5,3 ΠΈ 7,8 ΠΊΠΈΠ»ΠΎΠΌΠ΅Ρ‚Ρ€Π° Π² 1 час, Π½Π΅ ΠΏΡ€Π΅Π²Ρ‹ΡˆΠ°Ρ допустимого значСния. ΠŸΡ€ΠΈ скорости 9,6 ΠΊΠΈΠ»ΠΎΠΌΠ΅Ρ‚Ρ€Π° Π² 1 час агротСхничСскиС трСбования Π½Π°Ρ€ΡƒΡˆΠ°Π»ΠΈΡΡŒ. (Π’Ρ‹Π²ΠΎΠ΄Ρ‹) РаздСльная ΡƒΠ±ΠΎΡ€ΠΊΠ° льна эффСктивна ΠΏΡ€ΠΈ Π²Ρ‹Π»Π΅ΠΆΠΊΠ΅ Π»ΡŒΠ½ΠΎΡΡ‹Ρ€ΡŒΡ Π² Ρ‚Π΅Ρ‡Π΅Π½ΠΈΠ΅ Ρ‚Ρ€Π΅Ρ… нСдСль. ΠŸΡ€ΠΈ ΠΎΠ±ΠΎΡ€Π°Ρ‡ΠΈΠ²Π°Π½ΠΈΠΈ нСочСсанных Π»Π΅Π½Ρ‚ рабочая ΡΠΊΠΎΡ€ΠΎΡΡ‚ΡŒ Π½Π΅ Π΄ΠΎΠ»ΠΆΠ½Π° ΠΏΡ€Π΅Π²Ρ‹ΡˆΠ°Ρ‚ΡŒ 9 ΠΊΠΈΠ»ΠΎΠΌΠ΅Ρ‚Ρ€ΠΎΠ² Π² 1 час

    Assessment of serological tests for antibodies to different antigens of the SARS-CoV-2 virus: comparison of six immunoassays

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    The new coronavirus SARS-CoV-2 has become a global challenge to medicine and, in particular, laboratory diagnostics. The study of the antibodies’ level to SARS-CoV-2 can be used as a confirmation test in the diagnosis of a disease, but it becomes of paramount importance in assessing population immunity resulting from a disease or vaccination, as well as in selection of convalescent plasma donors. The kits developed in our country and abroad for detecting antibodies to the SARS-CoV-2 virus differ both in the methods of testing and in the used coronavirus antigens to which the antibodies are directed. The aim of this study was to compare the diagnostic sensitivity and specificity of five kits for the detection of IgG antibodies to the SARS-CoV-2 virus, based on different diagnostic methods. Serum samples from 137 COVID-19 convalescents and 166 donors of blood and its components were examined. The control group consisted of 50 blood sera collected at the beginning of 2019 and 19 sera collected in 2018 (before the advent of the SARS-CoV-2 virus) and stored at -70 Β°C. Testing was carried out in analytical systems: rapid test β€œCOVID-19 IgM/IgG Rapid Test (Colloidal Gold)” (China), on an automatic immunochemical analyzer Abbott Architectβ„’ i2000 and kit β€œSARS-CoV2-IgG” (Abbot, Chicago , IL USA), by the chemiluminescence method using an automatic analyzer of the CL series and kits of the β€œMindray” company (China) β€œSARS-CoV-2 IgM” and β€œSARS-CoV-2 IgG” and by the enzyme immunoassay method on the kits of the companies β€œDiagnostic Systems” Ltd (Russia, Nizhny Novgorod) β€œDS-IFA-ANTI-SARS-CoV-2-G”, β€œXema” Ltd (Federal State Budgetary Institution β€œNational Medical Research Center of Hematology” of the Ministry of Health of Russia) β€œSARS-CoV-2-IgG-IFA” and β€œVector-Best” CJSC (Russia, Novosibirsk)” SARS-COV-2-IgM-IFA-BEST” and β€œSARS-COV-2-IgG-IFABEST”. When comparing the results of testing 137 plasma samples on the Vector-Best and Mindray kits for IgG antibodies, 127 samples were positive, 7 samples were negative on both kits, the discrepancy was 2.2%. In the study of IgM antibodies, 32.1% were positive, and 52.6% were negative in both kits. The discrepancy rate was 15.3%. Out of 166 samples, 1 serum (0.6%) was negative in 5 kits. On the Mindray kit, IgG antibodies to the antigens of the SARS-CoV-2 virus were detected in 165 samples (99.4%), on Vector-Best – in 164 sera (98.8%), on Diagnostic systems – in 151 (90.96%), on Xema – in 154 (92.8%), and on Abbott – in 155 samples (93.4%). At the same time, 135 (81.33%) samples were positive in all kits, while 30 samples had discordant results (18.07%), and in 9 sera, specific IgG was not detected in 2 or more kits. ROC analysis revealed a high diagnostic value of all tested kits (AUC from 0.908 to 0.998), which indicates a high quality of the separation model of positive and negative samples (p < 0.001). With the cut-off set by the manufacturers, the sensitivity and specificity ranged from 82.8% and 93.3% for the Diagnostic Systems kit to 99.4% and 95.8% for the VectorBest kit. The calculated correlation coefficients were higher between kits with a similar composition of the antigen used in the kits; therefore, it is better to monitor the dynamics of antibodies by diagnostic kits from the same manufacturer
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