139 research outputs found
Running around the vicious circle: Cold War images in the contemporary Russian and American print media
The article was submitted on 09.03.2016.Π‘ΡΠ°ΡΡΡ ΠΏΠΎΡΠ²ΡΡΠ΅Π½Π° ΡΡΠ°Π²Π½ΠΈΡΠ΅Π»ΡΠ½ΠΎ-ΡΡΠΈΠ»ΠΈΡΡΠΈΡΠ΅ΡΠΊΠΎΠΌΡ Π°Π½Π°Π»ΠΈΠ·Ρ ΠΏΠΎΠ»ΠΈΡΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ Π½Π°ΡΡΠ°ΡΠΈΠ²Π° Π ΠΎΡΡΠΈΠΈ ΠΈ Π‘Π¨Π Π²ΡΠ΅ΠΌΠ΅Π½ Ρ
ΠΎΠ»ΠΎΠ΄Π½ΠΎΠΉ Π²ΠΎΠΉΠ½Ρ 1950β1980 Π³Π³. ΠΈ 2015 Π³. Π ΠΊΠ°ΡΠ΅ΡΡΠ²Π΅ ΠΌΠ΅ΡΠΎΠ΄ΠΎΠ»ΠΎΠ³ΠΈΠΈ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ Π²ΡΠ±ΡΠ°Π½Π° ΠΊΠΎΠ³Π½ΠΈΡΠΈΠ²Π½Π°Ρ ΡΠ΅ΠΎΡΠΈΡ Π½Π°ΡΡΠ°ΡΠΈΠ²Π½ΠΎΠ³ΠΎ Π°Π½Π°Π»ΠΈΠ·Π°. ΠΠΎΠ»ΠΈΡΠΈΡΠ΅ΡΠΊΠΈΠΉ Π½Π°ΡΡΠ°ΡΠΈΠ² ΠΏΠΎΠ½ΠΈΠΌΠ°Π΅ΡΡΡ ΠΊΠ°ΠΊ Π΅Π΄ΠΈΠ½ΡΠΉ ΡΡΠΆΠ΅Ρ, ΠΎΠ±ΡΠ΅Π΄ΠΈΠ½ΡΡΡΠΈΠΉ ΠΌΠ½ΠΎΠΆΠ΅ΡΡΠ²ΠΎ ΠΏΡΠ±Π»ΠΈΡΠΈΡΡΠΈΡΠ΅ΡΠΊΠΈΡ
ΠΌΠ°ΡΠ΅ΡΠΈΠ°Π»ΠΎΠ² Π½Π° ΠΏΡΠΎΡΡΠΆΠ΅Π½ΠΈΠΈ ΠΎΠΏΡΠ΅Π΄Π΅Π»Π΅Π½Π½ΠΎΠ³ΠΎ ΠΈΡΡΠΎΡΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΠΏΠ΅ΡΠΈΠΎΠ΄Π° ΠΈ ΠΎΡΡΠ°ΠΆΠ°ΡΡΠΈΠΉ Π³ΠΎΡΡΠ΄Π°ΡΡΡΠ²Π΅Π½Π½ΡΡ ΠΈΠ΄Π΅ΠΎΠ»ΠΎΠ³ΠΈΡ Ρ ΡΡΠ»ΠΎΠ²Π½ΡΠΌ Π½Π°Π·Π²Π°Π½ΠΈΠ΅ΠΌ, ΠΏΠΎΡΡΠΎΡΠ½Π½ΡΠΌΠΈ ΠΏΠ΅ΡΡΠΎΠ½Π°ΠΆΠ°ΠΌΠΈ, Π²ΡΠΏΠΎΠ»Π½ΡΡΡΠΈΠΌΠΈ ΠΏΠΎΠ»ΠΎΠΆΠΈΡΠ΅Π»ΡΠ½ΡΠ΅ Π»ΠΈΠ±ΠΎ ΠΎΡΡΠΈΡΠ°ΡΠ΅Π»ΡΠ½ΡΠ΅ ΡΠΎΠ»ΠΈ, Π²Π΅ΡΠ±Π°Π»ΡΠ½ΠΎ ΠΏΡΠ΅Π΄ΡΡΠ°Π²Π»Π΅Π½Π½ΡΠΉ ΠΏΠΎΠ²ΡΠΎΡΡΡΡΠΈΠΌΠΈΡΡ Π»Π΅ΠΊΡΠΈΡΠ΅ΡΠΊΠΈΠΌΠΈ Π΅Π΄ΠΈΠ½ΠΈΡΠ°ΠΌΠΈ, ΡΡΠΈΠ»ΠΈΡΡΠΈΡΠ΅ΡΠΊΠΈΠΌΠΈ ΠΈ ΠΌΠ°Π½ΠΈΠΏΡΠ»ΡΡΠΈΠ²Π½ΡΠΌΠΈ ΠΏΡΠΈΠ΅ΠΌΠ°ΠΌΠΈ. Π£ΡΡΠ°Π½ΠΎΠ²Π»Π΅Π½ΠΎ, ΡΡΠΎ ΡΠΎΠ²Π΅ΡΡΠΊΠΈΠΉ Π½Π°ΡΡΠ°ΡΠΈΠ² Π²ΡΠ΅ΠΌΠ΅Π½ Ρ
ΠΎΠ»ΠΎΠ΄Π½ΠΎΠΉ Π²ΠΎΠΉΠ½Ρ ΠΈΠΌΠ΅Π» ΡΠ΅ΡΠΊΠΎ ΠΏΡΠΎΠΏΠΈΡΠ°Π½Π½ΡΡ
ΠΎΡΡΠΈΡΠ°ΡΠ΅Π»ΡΠ½ΡΡ
Π³Π΅ΡΠΎΠ΅Π²-ΠΊΠ°ΠΏΠΈΡΠ°Π»ΠΈΡΡΠΎΠ², ΡΠΎΠ»Ρ ΠΈΡ
ΠΆΠ΅ΡΡΠ² ΠΏΡΠΈΠ½Π°Π΄Π»Π΅ΠΆΠ°Π»Π° ΠΏΡΠΎΡΡΡΠΌ ΠΆΠΈΡΠ΅Π»ΡΠΌ ΠΊΠ°ΠΏΠΈΡΠ°Π»ΠΈΡΡΠΈΡΠ΅ΡΠΊΠΈΡ
ΡΡΡΠ°Π½; ΠΏΠΎΠ»ΠΎΠΆΠΈΡΠ΅Π»ΡΠ½ΡΠΌΠΈ Π³Π΅ΡΠΎΡΠΌΠΈ-ΡΠΏΠ°ΡΠΈΡΠ΅Π»ΡΠΌΠΈ Π²ΡΡΡΡΠΏΠ°Π»ΠΈ ΠΊΠΎΠΌΠΌΡΠ½ΠΈΡΡΡ. ΠΠ½ Ρ
Π°ΡΠ°ΠΊΡΠ΅ΡΠΈΠ·ΠΎΠ²Π°Π»ΡΡ ΠΎΠΏΡΠ΅Π΄Π΅Π»Π΅Π½Π½ΡΠΌΠΈ ΡΠΏΠ΅ΡΠΈΡΠΈΡΠ΅ΡΠΊΠΈΠΌΠΈ ΡΠ΅ΡΡΠ°ΠΌΠΈ: ΡΠΎΡΠΌΠΈΡΠΎΠ²Π°Π½ΠΈΠ΅ ΡΠ΅ΡΠΊΠΎΠΉ ΠΎΠΏΠΏΠΎΠ·ΠΈΡΠΈΠΈ Β«ΡΠ²ΠΎΠΉ β ΡΡΠΆΠΎΠΉΒ»; Π²ΡΠ±ΠΎΡΠΎΡΠ½ΠΎΠ΅ ΠΎΡΠ²Π΅ΡΠ΅Π½ΠΈΠ΅ ΠΏΡΠΎΠΈΡΡ
ΠΎΠ΄ΡΡΠΈΡ
Π²ΠΎ Β«Π²ΡΠ°ΠΆΠ΄Π΅Π±Π½ΠΎΠΉΒ» ΡΡΡΠ°Π½Π΅ ΡΠΎΠ±ΡΡΠΈΠΉ, ΡΠ΅Π½Π΄Π΅Π½ΡΠΈΡ ΠΊ ΠΈΡΠΊΠ»ΡΡΠ΅Π½ΠΈΡ Π²ΡΠ΅Π³ΠΎ ΠΏΠΎΠ»ΠΎΠΆΠΈΡΠ΅Π»ΡΠ½ΠΎΠ³ΠΎ; ΠΎΠ΄Π½ΠΎΠ±ΠΎΠΊΠΎΠ΅, ΠΏΡΠ΅Π΄Π²Π·ΡΡΠΎΠ΅, ΡΠΈΠ»ΡΠ½ΠΎ Π°Π½Π³Π°ΠΆΠΈΡΠΎΠ²Π°Π½Π½ΠΎΠ΅ ΠΏΡΠ΅Π΄ΡΡΠ°Π²Π»Π΅Π½ΠΈΠ΅ ΠΏΠΎΠ»ΠΈΡΠΈΡΠ΅ΡΠΊΠΈΡ
, ΡΠΊΠΎΠ½ΠΎΠΌΠΈΡΠ΅ΡΠΊΠΈΡ
ΠΈ ΠΊΡΠ»ΡΡΡΡΠ½ΡΡ
ΡΠΎΠ±ΡΡΠΈΠΉ (Π²ΡΡΠ²Π΅ΡΠΈΠ²Π°Π½ΠΈΠ΅ ΠΏΠΎΠ»ΠΎΠΆΠΈΡΠ΅Π»ΡΠ½ΠΎΠ³ΠΎ Π² Π½Π°ΡΠ΅ΠΉ ΡΡΡΠ°Π½Π΅, ΠΏΡΠ΅ΡΠ²Π΅Π»ΠΈΡΠ΅Π½ΠΈΠ΅ ΡΠ΅Π·ΠΊΠΎ ΠΎΡΡΠΈΡΠ°ΡΠ΅Π»ΡΠ½ΠΎΠ³ΠΎ Π² Π·Π°ΠΏΠ°Π΄Π½ΡΡ
ΡΡΡΠ°Π½Π°Ρ
); ΡΠΌΠΎΡΠΈΠΎΠ½Π°Π»ΡΠ½Π°Ρ Π½Π°ΠΏΠΎΠ»Π½Π΅Π½Π½ΠΎΡΡΡ ΠΎΠ±ΡΠ°Π·Π° Β«ΡΡΠΆΠΎΠ³ΠΎΒ» Π±Π»Π°Π³ΠΎΠ΄Π°ΡΡ ΡΠΎΠΎΡΠ²Π΅ΡΡΡΠ²ΡΡΡΠΈΠΌ ΡΠ·ΡΠΊΠΎΠ²ΡΠΌ ΠΈ Π½Π΅ΡΠ·ΡΠΊΠΎΠ²ΡΠΌ ΡΡΠ΅Π΄ΡΡΠ²Π°ΠΌ; ΡΠΎΡΠΌΠΈΡΠΎΠ²Π°Π½ΠΈΠ΅ ΡΡΠΎΠΉΠΊΠΎΠ³ΠΎ ΠΎΡΡΠΈΡΠ°ΡΠ΅Π»ΡΠ½ΠΎΠ³ΠΎ ΠΎΠ±ΡΠ°Π·Π° Β«ΡΡΠΆΠΎΠ³ΠΎΒ» Π·Π° ΡΡΠ΅Ρ ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π½ΠΈΡ ΠΈΠ·Π½Π°ΡΠ°Π»ΡΠ½ΠΎ Π»ΠΎΠΆΠ½ΡΡ
ΠΏΡΠΈΡΠΈΠ½Π½ΠΎ-ΡΠ»Π΅Π΄ΡΡΠ²Π΅Π½Π½ΡΡ
ΡΠ²ΡΠ·Π΅ΠΉ (ΠΈΠ½ΡΠΈΠ½ΡΠ°ΡΠΈΠΉ, Π»ΠΎΠΆΠ½ΡΡ
ΠΏΡΠ΅ΡΡΠΏΠΏΠΎΠ·ΠΈΡΠΈΠΉ, ΠΏΡΠΎΠ²ΠΎΠΊΠ°ΡΠΈΠΉ); ΡΠ΅ΡΡΠ΅ΠΉΠΌΠΈΠ½Π³ ΠΊΠΎΠ³Π½ΠΈΡΠΈΠ²Π½ΡΡ
ΠΏΡΠ΅Π΄ΡΡΠ°Π²Π»Π΅Π½ΠΈΠΉ ΠΎ ΡΠΎΠ±ΡΡΠΈΡΡ
Π² ΠΌΠΈΡΠ΅, ΠΊΠΎΠ³Π΄Π° ΠΎΠ΄Π½ΠΎ ΠΈ ΡΠΎ ΠΆΠ΅ ΡΠΎΠ±ΡΡΠΈΠ΅ ΡΡΠ°ΠΊΡΡΠ΅ΡΡΡ ΠΏΠΎ-ΡΠ°Π·Π½ΠΎΠΌΡ Π² ΡΠΈΠ»Ρ ΡΡΡΠ΅ΡΡΠ²ΡΡΡΠ΅ΠΉ ΠΈΠ΄Π΅ΠΎΠ»ΠΎΠ³ΠΈΠΈ; ΠΎΠ±ΡΡΠ²Π»Π΅Π½ΠΈΠ΅ ΡΠΎΠ±ΡΡΠ²Π΅Π½Π½ΡΡ
ΡΠ΅Π½Π½ΠΎΡΡΠ΅ΠΉ ΠΌΠΎΡΠ°Π»ΡΠ½ΡΠΌΠΈ, Π° ΡΠ΅Π½Π½ΠΎΡΡΠ΅ΠΉ Β«ΡΡΠΆΠΎΠ³ΠΎΒ» Π±Π΅Π·Π½ΡΠ°Π²ΡΡΠ²Π΅Π½Π½ΡΠΌΠΈ. Π ΠΎΡΡΠΈΠΉΡΠΊΠΈΠΉ ΠΏΠΎΠ»ΠΈΡΠΈΡΠ΅ΡΠΊΠΈΠΉ Π½Π°ΡΡΠ°ΡΠΈΠ² ΠΏΠΎΡΠ»Π΅Π΄Π½ΠΈΡ
Π»Π΅Ρ ΠΏΠΎΠ΄Π΄Π΅ΡΠΆΠΈΠ²Π°Π΅Ρ ΡΡΠ΅Π½Π°ΡΠΈΠΉ ΠΏΠΎΠ΄ ΡΡΠ»ΠΎΠ²Π½ΡΠΌ Π½Π°Π·Π²Π°Π½ΠΈΠ΅ΠΌ Β«Π Π½Π°ΠΌ Π²ΡΠ΅ ΡΠ°Π²Π½ΠΎ β ΠΌΡ Π½Π΅ Π±ΠΎΠΈΠΌΡΡ βΡΠ°Π½ΠΊΡΠΈΠΎΠ½Π½ΡΡ
ΡΠΌΠΎΡΡΠΈΡΠ΅Π»Π΅ΠΉβΒ», Π² ΡΠΎΠ»ΠΈ ΠΊΠΎΡΠΎΡΡΡ
Π²ΡΡΡΡΠΏΠ°ΡΡ ΠΏΡΠ΅Π·ΠΈΠ΄Π΅Π½Ρ Π‘Π¨Π ΠΈ Π»ΠΈΠ΄Π΅ΡΡ Π²Π΅Π΄ΡΡΠΈΡ
Π·Π°ΠΏΠ°Π΄Π½ΡΡ
ΡΡΡΠ°Π½ β Β«Π±Π΅Π·Π²ΠΎΠ»ΡΠ½ΡΠ΅ ΠΌΠ°ΡΠΈΠΎΠ½Π΅ΡΠΊΠΈ, Π±Π΅Π·Π²Π»Π°ΡΡΠ½ΡΠ΅ ΡΡΠΊΠΎΠ²ΠΎΠ΄ΠΈΡΠ΅Π»ΠΈ ΡΠ²ΠΎΠΈΡ
Π³ΠΎΡΡΠ΄Π°ΡΡΡΠ²Β». Π‘ΡΠ΅Π½Π°ΡΠΈΠΉ ΠΆΠ΅ Π½Π°ΡΡΠ°ΡΠΈΠ²Π° Π°Π½Π³Π»ΠΎΡΠ·ΡΡΠ½ΠΎΠΉ Π·Π°ΠΏΠ°Π΄Π½ΠΎΠΉ ΠΏΡΠ΅ΡΡΡ: ΠΡΡΠΈΠ½ / Π ΠΎΡΡΠΈΡ Π²Π΅Π΄Π΅Ρ Π°Π³ΡΠ΅ΡΡΠΈΠ²Π½ΡΠ΅ Π΄Π΅ΠΉΡΡΠ²ΠΈΡ, Π²ΡΠ°ΠΆΠ΄Π΅Π±Π΅Π½ Π‘Π¨Π, ΡΠ²Π»ΡΠ΅ΡΡΡ ΠΈΡΡΠΎΡΠ½ΠΈΠΊΠΎΠΌ Π²ΠΎΠ΅Π½Π½ΡΡ
ΠΊΠΎΠ½ΡΠ»ΠΈΠΊΡΠΎΠ², Π½Π΅ΡΡΡΡΠΏΡΠΈΠ², Π½Π΅ΠΏΡΠ΅Π΄ΡΠΊΠ°Π·ΡΠ΅ΠΌ. Π‘Π¨Π Π½Π° ΡΠ»ΠΎΠ²Π°Ρ
ΠΎΡΡΡΠ°ΠΈΠ²Π°ΡΡ Π΄Π΅ΠΌΠΎΠΊΡΠ°ΡΠΈΡΠ½ΡΠ΅ ΡΠ΅Π½Π½ΠΎΡΡΠΈ, ΡΡΡΠ΅ΠΌΡΡΡΡ ΠΊ Π΄Π΅ΡΡΠΊΠ°Π»Π°ΡΠΈΠΈ Π²ΠΎΠΎΡΡΠΆΠ΅Π½Π½ΡΡ
ΠΏΡΠΎΡΠΈΠ²ΠΎΡΡΠΎΡΠ½ΠΈΠΉ, ΠΎΠΏΠ°ΡΠ°ΡΡΡΡ Π½Π΅ΠΏΡΠ΅Π΄ΡΠΊΠ°Π·ΡΠ΅ΠΌΠΎΡΡΠΈ Π΄ΠΈΠΊΠΎΠΉ Π ΠΎΡΡΠΈΠΈ / ΠΡΡΠΈΠ½Π°. Π ΡΠΎΡΡΠΈΠΉΡΠΊΠΎΠΌ Π½Π°ΡΡΠ°ΡΠΈΠ²Π΅ ΠΏΡΠ΅ΠΎΠ±Π»Π°Π΄Π°ΡΡ ΠΏΡΠΈΠ΅ΠΌΡ ΠΈΡΠΎΠ½ΠΈΠΈ, ΡΠ°ΡΠΊΠ°Π·ΠΌΠ°, ΠΏΡΡΠΌΡΡ
Π½Π°ΡΠΌΠ΅ΡΠ΅ΠΊ ΠΈ ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π½ΠΈΡ ΠΎΠ±ΡΡΠ΅Π½Π½ΠΎΠΉ Π»Π΅ΠΊΡΠΈΠΊΠΈ Π² Π°Π΄ΡΠ΅Ρ ΠΎΠΏΠΏΠΎΠ½Π΅Π½ΡΠΎΠ²; Π² Π°Π½Π³Π»ΠΎΡΠ·ΡΡΠ½ΠΎΠΌ Π½Π°ΡΡΠ°ΡΠΈΠ²Π΅ Π΄ΠΎΠΌΠΈΠ½ΠΈΡΡΠ΅Ρ ΠΏΡΠΈΠ΅ΠΌ Π·Π°ΠΏΡΠ³ΠΈΠ²Π°Π½ΠΈΡ, ΠΊΠΎΠ³Π΄Π° Β«Π²ΡΠ°Π³Β» Π½ΠΎΠΌΠΈΠ½ΠΈΡΡΠ΅ΡΡΡ Π°Π³ΡΠ΅ΡΡΠΎΡΠΎΠΌ, Π½Π΅ΠΏΡΠ΅Π΄ΡΠΊΠ°Π·ΡΠ΅ΠΌΡΠΌ Π²Π°ΡΠ²Π°ΡΠΎΠΌ.The article presents a comparative stylistic analysis of the political narrative of Russia and the United States during two historical periods: the Cold War (1950β1980) and the year 2015. The authors choose the cognitive theory of narrative analysis as their research methodology. Political narrative is understood as a single story uniting multiple journalistic materials over a certain historical period of up to several decades, reflecting the state ideology with an arbitrary name, permanent positive or negative characters, and verbally presented via recurrent lexical units, stylistic and manipulation techniques. It is established that the Soviet narrative of the Cold War period had clearly defined villains β capitalists, while the role of victims belonged to ordinary citizens of the capitalist countries, and Communists were their saviors. The following specific features characterized the narrative: the formation of a clear opposition βus β themβ; selective coverage of events occurring in the βhostileβ countries, a tendency to the exclusion of anything positive; a one-sided, strongly biased view of the political, economic and cultural events (promoting the positive sides in this country and greatly exaggerating the negative ones in Western countries); an emotionally loaded image of βthemβ created by employing appropriate linguistic and non-linguistic means; the formation of a persistent negative image of βthemβ by the use of initially false causality (innuendo, false presuppositions, provocation); reframing cognitive representations of world events, when the same event is interpreted differently in different countries by the virtue of the existing ideology; declaration of oneβs own values as moral, and βtheirβ values as immoral. The Russian political narrative of last year supports a script called βWe donβt care β we are not afraid of βthe sanction mastersββ, that is, the US President and leaders of European countries β βpuppets, powerless heads of their statesβ. The scenario of the narrative, which is now being created in the English-language media concerning relations with Russia, is that Putin/Russia is aggressive, hostile to the United States; it is a source of military conflicts, uncompromising and unpredictable. The US defends democratic values, seeks de-escalation of the existing armed confrontations, and fears the wild unpredictability of Putin/Russia. The Russian narrative is dominated by the methods of irony, sarcasm, ridicule, and direct use of obscene language against its opponents; in the English narrative intimidation dominates, when the notion of βthemβ is referred to as an aggressor and unpredictable barbarian
A nonperturbative model for the strong running coupling within potential approach
A nonperturbative model for the QCD invariant charge, which contains no
low-energy unphysical singularities and possesses an elevated higher loop
corrections stability, is developed in the framework of potential approach. The
static quark-antiquark potential is constructed by making use of the proposed
model for the strong running coupling. The obtained result coincides with the
perturbative potential at small distances and agrees with relevant lattice
simulation data in the nonperturbative physically-relevant region. The
developed model yields a reasonable value of the QCD scale parameter, which is
consistent with its previous estimations obtained within potential approach.Comment: 14 pages, 4 figure
INFORMATION CULTURE AND INFORMATION SAFETY OF SCHOOLCHILDREN
Introduction. The article is devoted to the problem of interaction between schoolchildren and possible informational risks transmitted on the Internet. Considering the lack of external filters on the way of harmful information streams, it is actually necessary to develop information culture of schoolchildren, their abilities to sensibly and critically interpret the information on the Internet, and choice of adequate behaviour models surfing the Web.Β The aim of the present research is to analyze the state of informational safety of schoolchildren while using the Internet; gaining an understanding of the role of external restrictions and opportunities of intrapersonal filtration of the harmful Internet content depending on children age. Methodology and research methods. The methodology of the research is based on modern methods aimed to consider the problem of personal socialization in modern information society. Thus, the Internet Initiatives Development Fund (IIDF) questionnaire let the authors define the level of awareness of recipients on the problem under consideration. Results and scientific novelty. The theoretical analysis helped the authors predict the correlation of basic methods in order to guarantee personal safety of schoolchildren taking into account the process of maturity as well as the decrease of external filters that may stop harmful content. Empirical part of the research has enabled to reveal decrease in external control of staying of a child in network in the process of growing up against the background of restrictive attitudes prevalence among teachers and parents. Therefore, the research supposed to improve information culture of schoolchildren from the earliest ages encouraging them to sensibly and correctly interpret the information on the Internet. Practical significance. The practical recommendations to parents and teachers in order to improve informational personal safety of schoolchildren are proposed. The relevancy of information and communication competence increase among teachers and parents is emphasized.Β ΠΠ²Π΅Π΄Π΅Π½ΠΈΠ΅. Π‘ΡΠ°ΡΡΡ ΠΏΠΎΡΠ²ΡΡΠ΅Π½Π° ΠΏΡΠΎΠ±Π»Π΅ΠΌΠ΅ ΠΏΡΠΎΡΠΈΠ²ΠΎΡΡΠΎΡΠ½ΠΈΡ ΠΈΠ½ΡΠΎΡΠΌΠ°ΡΠΈΠΎΠ½Π½ΡΠΌ ΡΠΈΡΠΊΠ°ΠΌ, ΡΡΠ°Π½ΡΠ»ΠΈΡΡΠ΅ΠΌΡΠΌ ΡΠ΅ΡΠ΅Π· ΡΠ΅ΡΡ ΠΠ½ΡΠ΅ΡΠ½Π΅Ρ. Π ΡΠΈΡΡΠ°ΡΠΈΠΈ ΠΎΡΡΡΡΡΡΠ²ΠΈΡ Π²Π½Π΅ΡΠ½ΠΈΡ
ΠΏΡΠ΅Π³ΡΠ°Π΄ Π½Π° ΠΏΡΡΠΈ Π²ΡΠ΅Π΄ΠΎΠ½ΠΎΡΠ½ΡΡ
ΠΈΠ½ΡΠΎΡΠΌΠ°ΡΠΈΠΎΠ½Π½ΡΡ
ΠΏΠΎΡΠΎΠΊΠΎΠ² Π°ΠΊΡΡΠ°Π»ΠΈΠ·ΠΈΡΡΠ΅ΡΡΡ Π½Π΅ΠΎΠ±Ρ
ΠΎΠ΄ΠΈΠΌΠΎΡΡΡ ΡΠΎΡΠΌΠΈΡΠΎΠ²Π°Π½ΠΈΡ ΠΈΠ½ΡΠΎΡΠΌΠ°ΡΠΈΠΎΠ½Π½ΠΎΠΉ ΠΊΡΠ»ΡΡΡΡΡ ΡΠΊΠΎΠ»ΡΠ½ΠΈΠΊΠΎΠ²; ΠΈΡ
ΡΠΏΠΎΡΠΎΠ±Π½ΠΎΡΡΠΈ ΠΎΡΠΌΡΡΠ»Π΅Π½Π½ΠΎΠ³ΠΎ Π²ΠΎΡΠΏΡΠΈΡΡΠΈΡ ΠΈ ΠΊΡΠΈΡΠΈΡΠ΅ΡΠΊΠΎΠΉ ΠΎΡΠ΅Π½ΠΊΠΈ ΠΈΠ½ΡΠΎΡΠΌΠ°ΡΠΈΠΈ, ΠΏΠΎΡΠ΅ΡΠΏΠ½ΡΡΠΎΠΉ Π² ΡΠ΅ΡΠΈ; Π²ΡΠ±ΠΎΡΠ° Π°Π΄Π΅ΠΊΠ²Π°ΡΠ½ΡΡ
ΠΏΠΎΠ²Π΅Π΄Π΅Π½ΡΠ΅ΡΠΊΠΈΡ
ΠΌΠΎΠ΄Π΅Π»Π΅ΠΉ Π²ΠΎ Π²ΡΠ΅ΠΌΡ Π²ΡΡ
ΠΎΠ΄Π° Π² ΠΈΠ½ΡΠ΅ΡΠ½Π΅Ρ-ΠΏΡΠΎΡΡΡΠ°Π½ΡΡΠ²ΠΎ. Π¦Π΅Π»Ρ ΠΏΡΠ΅Π΄Π»Π°Π³Π°Π΅ΠΌΠΎΠ³ΠΎ Π²Π½ΠΈΠΌΠ°Π½ΠΈΡ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ β ΠΈΠ·ΡΡΠ΅Π½ΠΈΠ΅ ΡΠΎΡΡΠΎΡΠ½ΠΈΡ ΠΈΠ½ΡΠΎΡΠΌΠ°ΡΠΈΠΎΠ½Π½ΠΎΠΉ Π±Π΅Π·ΠΎΠΏΠ°ΡΠ½ΠΎΡΡΠΈ ΡΠΊΠΎΠ»ΡΠ½ΠΈΠΊΠΎΠ², Π²ΡΡΡΠ½Π΅Π½ΠΈΠ΅ ΡΠΎΠ»ΠΈ Π²Π½Π΅ΡΠ½ΠΈΡ
ΠΎΠ³ΡΠ°Π½ΠΈΡΠ΅Π½ΠΈΠΉ ΠΈ Π²ΠΎΠ·ΠΌΠΎΠΆΠ½ΠΎΡΡΠ΅ΠΉ Π²Π½ΡΡΡΠΈΠ»ΠΈΡΠ½ΠΎΡΡΠ½ΠΎΠΉ ΡΠΈΠ»ΡΡΡΠ°ΡΠΈΠΈ Π²ΡΠ΅Π΄ΠΎΠ½ΠΎΡΠ½ΠΎΠ³ΠΎ ΠΈΠ½ΡΠ΅ΡΠ½Π΅Ρ-ΠΊΠΎΠ½ΡΠ΅Π½ΡΠ° Π² Π·Π°Π²ΠΈΡΠΈΠΌΠΎΡΡΠΈ ΠΎΡ Π²ΠΎΠ·ΡΠ°ΡΡΠ° Π΄Π΅ΡΠ΅ΠΉ. ΠΠ΅ΡΠΎΠ΄ΠΎΠ»ΠΎΠ³ΠΈΡ ΠΈ ΠΌΠ΅ΡΠΎΠ΄ΠΈΠΊΠΈ. ΠΠ΅ΡΠΎΠ΄ΠΎΠ»ΠΎΠ³ΠΈΡ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ Π±Π°Π·ΠΈΡΡΠ΅ΡΡΡ Π½Π° ΡΠΎΠ²ΡΠ΅ΠΌΠ΅Π½Π½ΡΡ
ΠΏΠΎΠ΄Ρ
ΠΎΠ΄Π°Ρ
ΠΊ ΠΏΡΠΎΠ±Π»Π΅ΠΌΠ΅ ΡΠΎΡΠΈΠ°Π»ΠΈΠ·Π°ΡΠΈΠΈ Π»ΠΈΡΠ½ΠΎΡΡΠΈ. ΠΠ»Ρ ΠΎΠΏΡΠ΅Π΄Π΅Π»Π΅Π½ΠΈΡ ΡΡΠ΅ΠΏΠ΅Π½ΠΈ ΠΎΡΠ²Π΅Π΄ΠΎΠΌΠ»Π΅Π½Π½ΠΎΡΡΠΈ ΡΡΠ°ΡΠΈΡ
ΡΡ, ΠΈΡ
ΡΠΎΠ΄ΠΈΡΠ΅Π»Π΅ΠΉ ΠΈ ΠΏΠ΅Π΄Π°Π³ΠΎΠ³ΠΎΠ² Π² ΠΎΠ±Π»Π°ΡΡΠΈ ΠΈΠ½ΡΠΎΡΠΌΠ°ΡΠΈΠΎΠ½Π½ΠΎΠΉ Π±Π΅Π·ΠΎΠΏΠ°ΡΠ½ΠΎΡΡΠΈ ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π»ΡΡ Π°Π΄Π°ΠΏΡΠΈΡΠΎΠ²Π°Π½Π½ΡΠΉ Π²Π°ΡΠΈΠ°Π½Ρ ΠΎΠΏΡΠΎΡΠ½ΠΈΠΊΠ° Π€ΠΎΠ½Π΄Π° ΡΠ°Π·Π²ΠΈΡΠΈΡ ΠΠ½ΡΠ΅ΡΠ½Π΅Ρ. Π Π΅Π·ΡΠ»ΡΡΠ°ΡΡ ΠΈ Π½Π°ΡΡΠ½Π°Ρ Π½ΠΎΠ²ΠΈΠ·Π½Π°. Π’Π΅ΠΎΡΠ΅ΡΠΈΡΠ΅ΡΠΊΠΈΠΉ Π°Π½Π°Π»ΠΈΠ· ΠΏΠΎΠ·Π²ΠΎΠ»ΠΈΠ» ΡΡΡΠ°Π½ΠΎΠ²ΠΈΡΡ ΡΠΎΠΎΡΠ½ΠΎΡΠ΅Π½ΠΈΠ΅ ΠΎΡΠ½ΠΎΠ²Π½ΡΡ
β Π·Π°ΠΏΡΠ΅ΡΠΈΡΠ΅Π»ΡΠ½ΠΎ-ΠΎΠ³ΡΠ°Π½ΠΈΡΠΈΡΠ΅Π»ΡΠ½ΠΎΠ³ΠΎ ΠΈ Π»ΠΈΡΠ½ΠΎΡΡΠ½ΠΎ-ΡΠ°Π·Π²ΠΈΠ²Π°ΡΡΠ΅Π³ΠΎ β ΠΏΠΎΠ΄Ρ
ΠΎΠ΄ΠΎΠ² ΠΊ ΠΎΠ±Π΅ΡΠΏΠ΅ΡΠ΅Π½ΠΈΡ ΠΈΠ½ΡΠΎΡΠΌΠ°ΡΠΈΠΎΠ½Π½ΠΎΠΉ Π±Π΅Π·ΠΎΠΏΠ°ΡΠ½ΠΎΡΡΠΈ ΡΠΊΠΎΠ»ΡΠ½ΠΈΠΊΠΎΠ² Ρ ΡΡΠ΅ΡΠΎΠΌ Π·Π°ΠΊΠΎΠ½ΠΎΠΌΠ΅ΡΠ½ΠΎΡΡΠ΅ΠΉ ΠΈΡ
Π²Π·ΡΠΎΡΠ»Π΅Π½ΠΈΡ. ΠΠΌΠΏΠΈΡΠΈΡΠ΅ΡΠΊΠ°Ρ ΡΠ°ΡΡΡ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ ΠΏΠΎΠΊΠ°Π·Π°Π»Π° ΡΠ½ΠΈΠΆΠ΅Π½ΠΈΠ΅ Π²Π½Π΅ΡΠ½Π΅Π³ΠΎ ΠΊΠΎΠ½ΡΡΠΎΠ»Ρ ΠΏΡΠ΅Π±ΡΠ²Π°Π½ΠΈΡ ΡΠ΅Π±Π΅Π½ΠΊΠ° Π² ΡΠ΅ΡΠΈ ΠΏΠΎ ΠΌΠ΅ΡΠ΅ Π΅Π³ΠΎ Π²Π·ΡΠΎΡΠ»Π΅Π½ΠΈΡ Π½Π° ΡΠΎΠ½Π΅ ΠΏΡΠ΅ΠΎΠ±Π»Π°Π΄Π°Π½ΠΈΡ ΠΎΠ³ΡΠ°Π½ΠΈΡΠΈΡΠ΅Π»ΡΠ½ΡΡ
ΡΡΡΠ°Π½ΠΎΠ²ΠΎΠΊ Ρ ΠΏΠ΅Π΄Π°Π³ΠΎΠ³ΠΎΠ² ΠΈ ΡΠΎΠ΄ΠΈΡΠ΅Π»Π΅ΠΉ. Π ΡΠ²ΡΠ·ΠΈ Ρ ΠΎΠ±ΡΠ΅ΠΊΡΠΈΠ²Π½ΡΠΌΠΈ ΠΏΡΠΈΡΠΈΠ½Π°ΠΌΠΈ ΠΎΡΠ»Π°Π±Π»Π΅Π½ΠΈΡ Π²Π½Π΅ΡΠ½ΠΈΡ
ΠΎΠ³ΡΠ°Π½ΠΈΡΠΈΡΠ΅Π»ΡΠ½ΡΡ
ΡΠΈΠ»ΡΡΡΠΎΠ² Π½Π° ΠΏΡΡΠΈ Π²ΡΠ΅Π΄ΠΎΠ½ΠΎΡΠ½ΠΎΠ³ΠΎ ΠΊΠΎΠ½ΡΠ΅Π½ΡΠ° ΠΏΠΎ ΠΌΠ΅ΡΠ΅ ΡΠ°ΡΡΠΈΡΠ΅Π½ΠΈΡ ΡΠΎΡΠΈΠ°Π»ΡΠ½ΠΎΠΉ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΠΈ ΡΠ°Π·Π²ΠΈΠ²Π°ΡΡΠ΅ΠΉΡΡ Π»ΠΈΡΠ½ΠΎΡΡΠΈ ΠΎΠ±ΠΎΡΠ½ΠΎΠ²Π°Π½Π° Π½Π΅ΠΎΠ±Ρ
ΠΎΠ΄ΠΈΠΌΠΎΡΡΡ Π»ΠΈΡΠ½ΠΎΡΡΠ½ΠΎ-ΡΠ°Π·Π²ΠΈΠ²Π°ΡΡΠ΅Π³ΠΎ ΠΏΠΎΠ΄Ρ
ΠΎΠ΄Π° ΠΊ ΡΠΎΡΠΌΠΈΡΠΎΠ²Π°Π½ΠΈΡ ΠΈΠ½ΡΠΎΡΠΌΠ°ΡΠΈΠΎΠ½Π½ΠΎΠΉ ΠΊΡΠ»ΡΡΡΡΡ Π΄Π΅ΡΠ΅ΠΉ Π½Π°ΡΠΈΠ½Π°Ρ Ρ ΡΠ°Π½Π½Π΅Π³ΠΎ Π²ΠΎΠ·ΡΠ°ΡΡΠ°. ΠΡΠ°ΠΊΡΠΈΡΠ΅ΡΠΊΠ°Ρ Π·Π½Π°ΡΠΈΠΌΠΎΡΡΡ. Π‘ΡΠΎΡΠΌΡΠ»ΠΈΡΠΎΠ²Π°Π½Ρ ΡΠ΅ΠΊΠΎΠΌΠ΅Π½Π΄Π°ΡΠΈΠΈ ΠΏΠΎ ΡΠ΅Π°Π»ΠΈΠ·Π°ΡΠΈΠΈ ΠΌΠ΅Ρ ΠΈΠ½ΡΠΎΡΠΌΠ°ΡΠΈΠΎΠ½Π½ΠΎΠΉ Π±Π΅Π·ΠΎΠΏΠ°ΡΠ½ΠΎΡΡΠΈ ΡΠΊΠΎΠ»ΡΠ½ΠΈΠΊΠΎΠ² Π½Π° ΡΠ°Π·Π½ΡΡ
ΡΡΡΠΏΠ΅Π½ΡΡ
ΠΎΠ±ΡΡΠ΅Π½ΠΈΡ. ΠΠΎΠ΄ΡΠ΅ΡΠΊΠ½ΡΡΠ° Π½Π΅ΠΎΠ±Ρ
ΠΎΠ΄ΠΈΠΌΠΎΡΡΡ ΠΏΠΎΠ²ΡΡΠ΅Π½ΠΈΡ ΠΈΠ½ΡΠΎΡΠΌΠ°ΡΠΈΠΎΠ½Π½ΠΎ-ΠΊΠΎΠΌΠΌΡΠ½ΠΈΠΊΠ°ΡΠΈΠΎΠ½Π½ΠΎΠΉ ΠΊΠΎΠΌΠΏΠ΅ΡΠ΅Π½ΡΠ½ΠΎΡΡΠΈ ΠΏΠ΅Π΄Π°Π³ΠΎΠ³ΠΎΠ² ΠΈ ΡΠΎΠ΄ΠΈΡΠ΅Π»Π΅ΠΉ ΡΡΠ°ΡΠΈΡ
ΡΡ.
Abundance analysis of two late A-type stars HD 32115 and HD 37594
We have performed abundance analysis of two slowly rotating, late A-type
stars, HD 32115 (HR 1613) and HD 37594 (HR 1940), based on obtained echelle
spectra covering the spectral range 4000-9850 AAngstrom. These spectra allowed
us to identify an extensive line list for 31 chemical elements, the most
complete to date for A-type stars. Two approaches to abundance analysis were
used, namely a ``manual'' (interactive) and a semi-automatic procedure for
comparison of synthetic and observed spectra and equivalent widths. For some
elements non-LTE (NLTE) calculations were carried out and the corresponding
corrections have been applied. The abundance pattern of HD 32115 was found to
be very close to the solar abundance pattern, and thus may be used as an
abundance standard for chemical composition studies in middle and late A stars.
Further, its H-alpha line profile shows no core-to-wing anomaly like that found
for cool Ap stars and therefore also may be used as a standard in comparative
studies of the atmospheric structures of cool, slowly rotating Ap stars. HD
37594 shows a metal deficiency at the level of -0.3 dex for most elements and
triangle-like cores of spectral lines. This star most probably belongs to the
Delta Scuti group.Comment: 10 pages, 4 figure
1,3-Disubstituted p-tert-butylcalix[4]arenes as cholinesterase inhibitors
The inhibitory effect of 1,3-substituted p-tert-butylcalix[4]arenes on butyrylcholinesterase from horse serum has been discovered and kinetically investigated with photometric microassay techniques. The interaction of calix[4]arene with the enzyme is described in accordance with the formal kinetics of competitive reversible inhibition. The inhibition constants calculated depend on the substituent in the lower rim of the calix[4]arene and vary in the range of (5-110) Γ 10-6 M. The proposed mechanism of inhibition involves the cooperative interaction of indophenyl acetate used as a substrate, calix[4]arene and the enzyme without any covalent or electrostatic binding of the functional groups in the active site of cholinesterase. This results in the coordination of the calixarene on the enzyme surface in the proximity of the enzyme active site. Such interaction prevents the substrate from entering the enzyme active site
Selection of a SARS-CoV-2 antibody quantification method and development of an antibody reference standard for ELISA to test immunoglobulin preparations
TheΒ development of COVID-globulin, aΒ COVID-19-specific human immunoglobulin preparation, involved choosing aΒ method toΒ quantify antibodies to SARS-CoV-2. Antibody titre determination by virus neutralisation (VN) is labour-intensive and unsuitable for large-scale application. ToΒ enable routine testing, it was necessary toΒ develop aΒ less demanding method; theΒ enzyme-linked immunosorbent assay (ELISA) was theΒ most appropriate of solutions. TheΒ lack of international and industry reference standards (RS) prompted theΒ preparation and certification of anΒ RS for COVID-globulin potency control.TheΒ aim of theΒ study was toΒ examine theΒ possibility of substituting ELISA for VN and to develop anΒ RS for SARS-CoV-2 antibody quantification in immunoglobulin preparations.Materials and methods: theΒ authors used commercial ELISA kits by several manufacturers, COVID-globulin by Microgen (48 batches), and human plasma samples from multiple sources (1499 samples). TheΒ tests were performed by VN, ELISA, and chemiluminescent microparticle immunoassay.Results: theΒ authors validated anΒ ELISA method for SARS-CoV-2 antibody quantification with theΒ selected reagent kits by theΒ National Medical Research Center for Hematology (NMRC for Hematology) and Euroimmun AG. TheΒ authors demonstrated theΒ possibility of using ELISA instead of VN (with aΒ correlation coefficient of more than 0.9). They developed and characterised anΒ in-houseΒ RS for SARS-CoV-2 antibody content in human immunoglobulin preparations. TheΒ RS was certified in newly introduced anti-COVID units (ACU) and in international binding antibody units (BAU) using the World Health Organisation (WHO) international reference panel (NIBSC code: 20/268). TheΒ RS's potency was measured in terms of its neutralising activity in ACU (320 ACU/mL) and BAU (2234.8 BAU/mL). TheΒ authors established theΒ relationship between ACU and BAU units. For theΒ selected ELISA reagent kits, theΒ conversion factors were 6.4 (NMRC for Hematology) and 7.0 (Euroimmun AG).Conclusions: theΒ ELISA method for SARS-CoV-2 antibody quantification and theΒ RS for SARS-CoV-2 antibody content can be applied toΒ determine theΒ potency of human anti-COVID-19 immunoglobulins
Discrimination of apple juice and herbal liqueur brands with solid-state electrodes covered with polyaniline and thiacalixarenes
Solid-contact ion-selective electrodes based on glassy carbon electrode covered with electropolymerized polyaniline and tetrasubstituted thiacalix[4]arene ionophores with hexyl and o-pyridylamido functional groups at the lower rim have been developed and examined in the discrimination of the brands of apple juices and herbal liqueurs. For this purpose, the liquids tested were diluted and spiked with a constant amount of Fe3+ ions. The variation of the signal toward Fe3+ ions was achieved due to their involvement in the reactions with the organic ligands and the antioxidants present. As was shown, the combination of the three electrodes with various receptors makes it possible to predict the brand of apple juices and herbal liqueurs using linear discriminant analysis in 95-100% cases. The discrimination procedure makes it possible to discriminate liquids within 20 min. Besides, the electrodes developed make it possible to detect individual antioxidants (ascorbic, malic, oxalic acids, hydroquinone, and quercetin) in the range from 5.0 Γ 10-6 to 1.0 Γ 10-2 M in direct potentiometric measurements and redox titration. Β© 2010 Elsevier B.V. All rights reserved
ΠΠΠΠ‘ΠΠΠΠΠΠΠ ΠΠ‘Π‘ΠΠΠΠΠΠΠΠΠ― ΠΠ ΠΠΠ’ΠΠΠΠΠΠ¦ΠΠ Π‘ΠΠ‘Π’ΠΠΠ« ΠΠΠΠΠΠΠΠ― Π₯ΠΠ Π£Π ΠΠΠ§ΠΠ‘ΠΠΠ Π‘Π’ΠΠΠΠ’ΠΠΠΠΠΠ§ΠΠ‘ΠΠΠ ΠΠΠΠΠ©Π ΠΠΠ¦ΠΠΠΠ’ΠΠ Π‘ ΠΠΠ§-ΠΠΠ€ΠΠΠ¦ΠΠΠ. ΠΠΠΠΠΠ’ΠΠ§ΠΠ‘ΠΠΠ ΠΠΠΠΠ ΠΠΠ’ΠΠ ΠΠ’Π£Π Π«
The article presents an analysis of the Russian and foreign specialized literature on the problem of dental rehabilitation of patients with HIV infection. It has been revealed that the structure and prevalence of dental surgical pathology in HIV infection has not been studied to date, the indices of the need for treatment of diseases of the dental profile have not been determined. Unsatisfactory access to qualified dental care has been identified, including due to discrimination and stigmatization by health professionals regarding both the disease itself and patients with HIV infection. The urgency of improving the system of rendering surgical dental care to HIV-infected with the aim of ensuring the maximum achievable level of health is substantiated. The data of the presented analytical review represent an important theoretical basis for the development of new tactical approaches to the implementation of the strategic direction of dental implant treatment of people living with HIV to expand access to this medical service.Π ΡΡΠ°ΡΡΠ΅ ΠΏΡΠ΅Π΄ΡΡΠ°Π²Π»Π΅Π½ Π°Π½Π°Π»ΠΈΠ· Π΄Π°Π½Π½ΡΡ
ΠΎΡΠ΅ΡΠ΅ΡΡΠ²Π΅Π½Π½ΠΎΠΉ ΠΈ Π·Π°ΡΡΠ±Π΅ΠΆΠ½ΠΎΠΉ ΡΠΏΠ΅ΡΠΈΠ°Π»ΡΠ½ΠΎΠΉ Π»ΠΈΡΠ΅ΡΠ°ΡΡΡΡ ΠΏΠΎ ΠΏΡΠΎΠ±Π»Π΅ΠΌΠ΅ ΡΡΠΎΠΌΠ°ΡΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΎΠΉ ΡΠ΅Π°Π±ΠΈΠ»ΠΈΡΠ°ΡΠΈΠΈ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ² Ρ ΠΠΠ§ΠΈΠ½ΡΠ΅ΠΊΡΠΈΠ΅ΠΉ. ΠΡΡΠ²Π»Π΅Π½ΠΎ, ΡΡΠΎ Π΄ΠΎ Π½Π°ΡΡΠΎΡΡΠ΅Π³ΠΎ Π²ΡΠ΅ΠΌΠ΅Π½ΠΈ Π½Π΅ ΠΈΠ·ΡΡΠ΅Π½Π° ΡΡΡΡΠΊΡΡΡΠ° ΠΈ ΡΠ°ΡΠΏΡΠΎΡΡΡΠ°Π½ΡΠ½Π½ΠΎΡΡΡ ΡΡΠΎΠΌΠ°ΡΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΎΠΉ Ρ
ΠΈΡΡΡΠ³ΠΈΡΠ΅ΡΠΊΠΎΠΉ ΠΏΠ°ΡΠΎΠ»ΠΎΠ³ΠΈΠΈ ΠΏΡΠΈ ΠΠΠ§-ΠΈΠ½ΡΠ΅ΠΊΡΠΈΠΈ, Π½Π΅ ΠΎΠΏΡΠ΅Π΄Π΅Π»Π΅Π½Ρ ΠΏΠΎΠΊΠ°Π·Π°ΡΠ΅Π»ΠΈ Π½ΡΠΆΠ΄Π°Π΅ΠΌΠΎΡΡΠΈ Π² Π»Π΅ΡΠ΅Π½ΠΈΠΈ Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΠΉ ΡΡΠΎΠΌΠ°ΡΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΠΏΡΠΎΡΠΈΠ»Ρ. ΠΡΡΠ²Π»Π΅Π½ Π½Π΅ΡΠ΄ΠΎΠ²Π»Π΅ΡΠ²ΠΎΡΠΈΡΠ΅Π»ΡΠ½ΡΠΉ Π΄ΠΎΡΡΡΠΏ ΠΊ ΠΊΠ²Π°Π»ΠΈΡΠΈΡΠΈΡΠΎΠ²Π°Π½Π½ΠΎΠΉ ΡΡΠΎΠΌΠ°ΡΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΎΠΉ ΠΏΠΎΠΌΠΎΡΠΈ, Π² ΡΠΎΠΌ ΡΠΈΡΠ»Π΅ ΠΈΠ·-Π·Π° Π΄ΠΈΡΠΊΡΠΈΠΌΠΈΠ½Π°ΡΠΈΠΈ ΠΈ ΡΡΠΈΠ³ΠΌΠ°ΡΠΈΠ·Π°ΡΠΈΠΈ ΡΠΎ ΡΡΠΎΡΠΎΠ½Ρ ΠΌΠ΅Π΄ΠΈΡΠΈΠ½ΡΠΊΠΈΡ
ΡΠ°Π±ΠΎΡΠ½ΠΈΠΊΠΎΠ² Π² ΠΎΡΠ½ΠΎΡΠ΅Π½ΠΈΠΈ ΠΊΠ°ΠΊ ΡΠ°ΠΌΠΎΠ³ΠΎ Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΡ, ΡΠ°ΠΊ ΠΈ Π±ΠΎΠ»ΡΠ½ΡΡ
ΠΠΠ§-ΠΈΠ½ΡΠ΅ΠΊΡΠΈΠ΅ΠΉ. ΠΠ±ΠΎΡΠ½ΠΎΠ²Π°Π½Π° Π°ΠΊΡΡΠ°Π»ΡΠ½ΠΎΡΡΡ ΡΠΎΠ²Π΅ΡΡΠ΅Π½ΡΡΠ²ΠΎΠ²Π°Π½ΠΈΡ ΡΠΈΡΡΠ΅ΠΌΡ ΠΎΠΊΠ°Π·Π°Π½ΠΈΡ Ρ
ΠΈΡΡΡΠ³ΠΈΡΠ΅ΡΠΊΠΎΠΉ ΡΡΠΎΠΌΠ°ΡΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΎΠΉ ΠΏΠΎΠΌΠΎΡΠΈ ΠΠΠ§-ΠΈΠ½ΡΠΈΡΠΈΡΠΎΠ²Π°Π½Π½ΡΠΌ Ρ ΡΠ΅Π»ΡΡ ΠΎΠ±Π΅ΡΠΏΠ΅ΡΠ΅Π½ΠΈΡ ΠΌΠ°ΠΊΡΠΈΠΌΠ°Π»ΡΠ½ΠΎ Π΄ΠΎΡΡΠΈΠΆΠΈΠΌΠΎΠ³ΠΎ ΡΡΠΎΠ²Π½Ρ Π·Π΄ΠΎΡΠΎΠ²ΡΡ. ΠΠ°Π½Π½ΡΠ΅ ΡΡΠΎΠ³ΠΎ Π°Π½Π°Π»ΠΈΡΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΠΎΠ±Π·ΠΎΡΠ° ΠΏΡΠ΅Π΄ΡΡΠ°Π²Π»ΡΡΡ Π²Π°ΠΆΠ½ΡΡ ΡΠ΅ΠΎΡΠ΅ΡΠΈΡΠ΅ΡΠΊΡΡ ΠΎΡΠ½ΠΎΠ²Ρ Π΄Π»Ρ ΡΠ°Π·ΡΠ°Π±ΠΎΡΠΊΠΈ Π½ΠΎΠ²ΡΡ
ΡΠ°ΠΊΡΠΈΡΠ΅ΡΠΊΠΈΡ
ΠΏΠΎΠ΄Ρ
ΠΎΠ΄ΠΎΠ² ΠΊ ΡΠ΅Π°Π»ΠΈΠ·Π°ΡΠΈΠΈ ΡΡΡΠ°ΡΠ΅Π³ΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ Π½Π°ΠΏΡΠ°Π²Π»Π΅Π½ΠΈΡ ΡΡΠΎΠΌΠ°ΡΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΠΈΠΌΠΏΠ»Π°Π½ΡΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ Π»Π΅ΡΠ΅Π½ΠΈΡ Π»ΡΠ΄Π΅ΠΉ, ΠΆΠΈΠ²ΡΡΠΈΡ
Ρ ΠΠΠ§, Π΄Π»Ρ ΡΠ°ΡΡΠΈΡΠ΅Π½ΠΈΡ Π΄ΠΎΡΡΡΠΏΠ° ΠΊ Π΄Π°Π½Π½ΠΎΠΉ ΠΌΠ΅Π΄ΠΈΡΠΈΠ½ΡΠΊΠΎΠΉ ΡΡΠ»ΡΠ³Π΅
ΠΡΠ΅Π½ΠΊΠ° ΠΊΠ°ΡΠ΅ΡΡΠ²Π° ΡΡΠ΅ΡΡΡ ΠΏΡΠΈ ΡΠ°Π·Π΄Π΅Π»ΡΠ½ΠΎΠΉ ΡΠ΅Ρ Π½ΠΎΠ»ΠΎΠ³ΠΈΠΈ ΡΠ±ΠΎΡΠΊΠΈ Π»ΡΠ½Π°-Π΄ΠΎΠ»Π³ΡΠ½ΡΠ°
The paper explores the technological aspects and methods involved in the preparation of flax straw within the framework of separate fiber flax harvesting technology. This particular technology allows for the prolonged maturation of seeds in the field. The study demonstrates that during the process of seasoning flax straw in the form of unprocessed stem ribbons, the seeds within the capsules undergo natural drying and ripening. This approach enables a reduction in fuel consumption compared to the traditional scheme while obtaining high-quality fiber and seeds suitable for sowing. (Research purpose) The objective of this study is to assess the quality of raw flax during the stage of straw flax preparation. (Materials and methods) The study investigates the processes and technical units involved in fiber flax harvesting, adhering to regulatory guidelines during the stages of stem pulling, seasoning, turning, picking, and processing are thoroughly examined. (Results and discussion) The research results have revealed the indicators for biological productivity of straw and seeds during the process of straw flax preparation. Under different seeding rates, the yield of straw flax ranges from 23.1 to 24.8 centners per hectare during a 14-day seasoning period and from 20.8 to 22.2 centners per hectare on the 21st day. These findings demonstrate that the average yield under various harvesting conditions is 20-30 centners per hectare. The flaxseed yield, ranging from 2.9 to 4.1 centners per hectare at different maturation periods, can be considered satisfactory. Furthermore, it was observed that the elongation of the flax ribbon increases after turning, compared to its initial state, when the combine speed is 5.3 and 7.8 kilometers per hour, remaining within the acceptable limits. However, at a speed of 9.6 kilometers per hour, there was a violation of agrotechnical requirements. (Conclusions) The separate harvesting of flax has proven to be effective during a three-week period of raw flax seasoning. It is important to note that when turning unprocessed flax ribbons, the working speed should not exceed 9 kilometers per hour.Π Π°ΡΡΠΌΠΎΡΡΠ΅Π»ΠΈ ΡΠ΅Ρ
Π½ΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΠ΅ Π°ΡΠΏΠ΅ΠΊΡΡ ΠΈ ΠΏΡΠΈΠ΅ΠΌΡ ΠΏΡΠΈΠ³ΠΎΡΠΎΠ²Π»Π΅Π½ΠΈΡ Π»ΡΠ½ΡΠ½ΠΎΠΉ ΡΡΠ΅ΡΡΡ ΠΏΡΠΈ ΡΠ°Π·Π΄Π΅Π»ΡΠ½ΠΎΠΌ ΡΠΏΠΎΡΠΎΠ±Π΅ ΡΠ±ΠΎΡΠΊΠΈ Π»ΡΠ½Π°-Π΄ΠΎΠ»Π³ΡΠ½ΡΠ°. ΠΠ°Π½Π½Π°Ρ ΡΠ΅Ρ
Π½ΠΎΠ»ΠΎΠ³ΠΈΡ ΠΏΠΎΠ·Π²ΠΎΠ»ΡΠ΅Ρ ΠΏΡΠΎΠ΄Π»ΠΈΡΡ ΡΠΎΠ·ΡΠ΅Π²Π°Π½ΠΈΠ΅ ΡΠ΅ΠΌΡΠ½ Π½Π° ΠΊΠΎΡΠ½Ρ. ΠΠΎΠΊΠ°Π·Π°Π»ΠΈ, ΡΡΠΎ Π·Π° Π²ΡΠ΅ΠΌΡ Π²ΡΠ»Π΅ΠΆΠΊΠΈ Π»ΡΠ½ΠΎΡΠΎΠ»ΠΎΠΌΡ Π² Π²ΠΈΠ΄Π΅ Π»Π΅Π½Ρ Π½Π΅ΠΎΡΠ΅ΡΠ°Π½Π½ΡΡ
ΡΡΠ΅Π±Π»Π΅ΠΉ ΡΠ΅ΠΌΠ΅Π½Π° Π² ΠΊΠΎΡΠΎΠ±ΠΎΡΠΊΠ°Ρ
ΠΏΠΎΠ΄ΡΡΡ
Π°ΡΡ ΠΈ Π΄ΠΎΠ·ΡΠ΅Π²Π°ΡΡ Π΅ΡΡΠ΅ΡΡΠ²Π΅Π½Π½ΡΠΌ ΠΎΠ±ΡΠ°Π·ΠΎΠΌ. ΠΡΠΎ ΠΏΠΎΠ·Π²ΠΎΠ»ΡΠ΅Ρ ΡΠ½ΠΈΠ·ΠΈΡΡ ΡΠ°ΡΡ
ΠΎΠ΄ ΡΠΎΠΏΠ»ΠΈΠ²Π½ΡΡ
ΡΠ΅ΡΡΡΡΠΎΠ² Π² ΡΡΠ°Π²Π½Π΅Π½ΠΈΠΈ Ρ ΡΡΠ°Π΄ΠΈΡΠΈΠΎΠ½Π½ΠΎΠΉ ΡΡ
Π΅ΠΌΠΎΠΉ, ΠΏΠΎΠ»ΡΡΠΈΡΡ ΠΊΠ°ΡΠ΅ΡΡΠ²Π΅Π½Π½ΠΎΠ΅ Π²ΠΎΠ»ΠΎΠΊΠ½ΠΎ ΠΈ ΠΏΡΠΈΠ³ΠΎΠ΄Π½ΡΠ΅ Π΄Π»Ρ ΠΏΠΎΡΠ΅Π²Π° ΡΠ΅ΠΌΠ΅Π½Π°. (Π¦Π΅Π»Ρ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ) ΠΡΠ΅Π½ΠΈΡΡ ΠΊΠ°ΡΠ΅ΡΡΠ²ΠΎ Π»ΡΠ½ΠΎΡΡΡΡΡ Π½Π° ΡΡΠ°ΠΏΠ΅ ΠΏΡΠΈΠ³ΠΎΡΠΎΠ²Π»Π΅Π½ΠΈΡ ΡΡΠ΅ΡΡΡ. (ΠΠ°ΡΠ΅ΡΠΈΠ°Π»Ρ ΠΈ ΠΌΠ΅ΡΠΎΠ΄Ρ) ΠΠ·ΡΡΠΈΠ»ΠΈ ΠΏΡΠΎΡΠ΅ΡΡΡ ΠΈ ΡΠ΅Ρ
Π½ΠΈΡΠ΅ΡΠΊΠΈΠ΅ ΡΡΠ΅Π΄ΡΡΠ²Π° ΠΏΡΠΈ ΡΠ±ΠΎΡΠΊΠ΅ Π»ΡΠ½Π°-Π΄ΠΎΠ»Π³ΡΠ½ΡΠ° Π² ΡΠΎΠΎΡΠ²Π΅ΡΡΡΠ²ΠΈΠΈ Ρ Π½ΠΎΡΠΌΠ°ΡΠΈΠ²Π½ΠΎΠΉ Π΄ΠΎΠΊΡΠΌΠ΅Π½ΡΠ°ΡΠΈΠ΅ΠΉ Π½Π° ΡΡΠ°ΠΏΠ°Ρ
Π²ΡΠ΄Π΅ΡΠ³ΠΈΠ²Π°Π½ΠΈΡ, Π²ΡΠ»Π΅ΠΆΠΊΠΈ, ΠΎΠ±ΠΎΡΠ°ΡΠΈΠ²Π°Π½ΠΈΡ, ΠΏΠΎΠ΄Π±ΠΎΡΠ° ΠΈ ΠΎΡΠ΅ΡΡΠ²Π°Π½ΠΈΡ ΡΡΠ΅Π±Π»Π΅ΠΉ. (Π Π΅Π·ΡΠ»ΡΡΠ°ΡΡ ΠΈ ΠΎΠ±ΡΡΠΆΠ΄Π΅Π½ΠΈΠ΅) ΠΠΏΡΠ΅Π΄Π΅Π»Π΅Π½Ρ ΠΏΠΎΠΊΠ°Π·Π°ΡΠ΅Π»ΠΈ Π±ΠΈΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΎΠΉ ΡΡΠΎΠΆΠ°ΠΉΠ½ΠΎΡΡΠΈ ΡΡΠ΅ΡΡΡ ΠΈ ΡΠ΅ΠΌΡΠ½ Π² ΠΏΡΠΎΡΠ΅ΡΡΠ΅ ΠΏΡΠΈΠ³ΠΎΡΠΎΠ²Π»Π΅Π½ΠΈΡ Π»ΡΠ½ΠΎΡΡΠ΅ΡΡΡ. ΠΡΠΈ ΡΠ°Π·Π»ΠΈΡΠ½ΠΎΠΉ Π½ΠΎΡΠΌΠ΅ Π²ΡΡΠ΅Π²Π° ΡΠ΅ΠΌΡΠ½ ΡΡΠΎΠΆΠ°ΠΉΠ½ΠΎΡΡΡ ΡΡΠ΅ΡΡΡ Π΄ΠΎΡΡΠΈΠ³Π°Π»Π° 23,1-24,8 ΡΠ΅Π½ΡΠ½Π΅ΡΠ° Π½Π° 1 Π³Π΅ΠΊΡΠ°Ρ ΠΈ ΡΡΠΎΠΊΠ΅ Π²ΡΠ»Π΅ΠΆΠΊΠΈ 14 Π΄Π½Π΅ΠΉ, Π° ΡΠ°ΠΊΠΆΠ΅ 20,8-22,2 ΡΠ΅Π½ΡΠ½Π΅ΡΠ° Π½Π° 1 Π³Π΅ΠΊΡΠ°Ρ Π½Π° 21-ΠΉ Π΄Π΅Π½Ρ. Π‘ΠΎΠ³Π»Π°ΡΠ½ΠΎ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡΠΌ ΡΡΠ΅Π΄Π½ΡΡ ΡΡΠΎΠΆΠ°ΠΉΠ½ΠΎΡΡΡ ΠΏΡΠΈ ΡΠ°Π·Π»ΠΈΡΠ½ΡΡ
ΡΡΠ»ΠΎΠ²ΠΈΡΡ
ΡΠ±ΠΎΡΠΊΠΈ ΡΠΎΡΡΠ°Π²Π»ΡΠ΅Ρ 20-30 ΡΠ΅Π½ΡΠ½Π΅ΡΠΎΠ² Ρ 1 Π³Π΅ΠΊΡΠ°ΡΠ°. Π£ΡΠΎΠΆΠ°ΠΉΠ½ΠΎΡΡΡ Π»ΡΠ½ΠΎΡΠ΅ΠΌΡΠ½ ΠΎΡ 2,9 Π΄ΠΎ 4,1 ΡΠ΅Π½ΡΠ½Π΅ΡΠ° Ρ 1 Π³Π΅ΠΊΡΠ°ΡΠ° ΠΏΡΠΈ ΡΠ°Π·Π½ΡΡ
ΡΡΠΎΠΊΠ°Ρ
Π²ΡΠ»Π΅ΠΆΠΊΠΈ ΠΌΠΎΠΆΠ½ΠΎ ΡΡΠΈΡΠ°ΡΡ Π²ΠΏΠΎΠ»Π½Π΅ Π΄ΠΎΠΏΡΡΡΠΈΠΌΠΎΠΉ. Π Π°ΡΡΡΠ½ΡΡΠΎΡΡΡ Π»Π΅Π½ΡΡ ΠΏΠΎΡΠ»Π΅ ΠΎΠ±ΠΎΡΠ°ΡΠΈΠ²Π°Π½ΠΈΡ Π²ΠΎΠ·ΡΠ°ΡΡΠ°Π»Π° ΠΏΠΎ ΡΡΠ°Π²Π½Π΅Π½ΠΈΡ Ρ ΠΈΡΡ
ΠΎΠ΄Π½ΠΎΠΉ ΠΏΡΠΈ ΡΠΊΠΎΡΠΎΡΡΠΈ ΠΊΠΎΠΌΠ±Π°ΠΉΠ½Π° 5,3 ΠΈ 7,8 ΠΊΠΈΠ»ΠΎΠΌΠ΅ΡΡΠ° Π² 1 ΡΠ°Ρ, Π½Π΅ ΠΏΡΠ΅Π²ΡΡΠ°Ρ Π΄ΠΎΠΏΡΡΡΠΈΠΌΠΎΠ³ΠΎ Π·Π½Π°ΡΠ΅Π½ΠΈΡ. ΠΡΠΈ ΡΠΊΠΎΡΠΎΡΡΠΈ 9,6 ΠΊΠΈΠ»ΠΎΠΌΠ΅ΡΡΠ° Π² 1 ΡΠ°Ρ Π°Π³ΡΠΎΡΠ΅Ρ
Π½ΠΈΡΠ΅ΡΠΊΠΈΠ΅ ΡΡΠ΅Π±ΠΎΠ²Π°Π½ΠΈΡ Π½Π°ΡΡΡΠ°Π»ΠΈΡΡ. (ΠΡΠ²ΠΎΠ΄Ρ) Π Π°Π·Π΄Π΅Π»ΡΠ½Π°Ρ ΡΠ±ΠΎΡΠΊΠ° Π»ΡΠ½Π° ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½Π° ΠΏΡΠΈ Π²ΡΠ»Π΅ΠΆΠΊΠ΅ Π»ΡΠ½ΠΎΡΡΡΡΡ Π² ΡΠ΅ΡΠ΅Π½ΠΈΠ΅ ΡΡΠ΅Ρ
Π½Π΅Π΄Π΅Π»Ρ. ΠΡΠΈ ΠΎΠ±ΠΎΡΠ°ΡΠΈΠ²Π°Π½ΠΈΠΈ Π½Π΅ΠΎΡΠ΅ΡΠ°Π½Π½ΡΡ
Π»Π΅Π½Ρ ΡΠ°Π±ΠΎΡΠ°Ρ ΡΠΊΠΎΡΠΎΡΡΡ Π½Π΅ Π΄ΠΎΠ»ΠΆΠ½Π° ΠΏΡΠ΅Π²ΡΡΠ°ΡΡ 9 ΠΊΠΈΠ»ΠΎΠΌΠ΅ΡΡΠΎΠ² Π² 1 ΡΠ°Ρ
Assessment of serological tests for antibodies to different antigens of the SARS-CoV-2 virus: comparison of six immunoassays
The new coronavirus SARS-CoV-2 has become a global challenge to medicine and, in particular, laboratory diagnostics. The study of the antibodiesβ level to SARS-CoV-2 can be used as a confirmation test in the diagnosis of a disease, but it becomes of paramount importance in assessing population immunity resulting from a disease or vaccination, as well as in selection of convalescent plasma donors. The kits developed in our country and abroad for detecting antibodies to the SARS-CoV-2 virus differ both in the methods of testing and in the used coronavirus antigens to which the antibodies are directed. The aim of this study was to compare the diagnostic sensitivity and specificity of five kits for the detection of IgG antibodies to the SARS-CoV-2 virus, based on different diagnostic methods. Serum samples from 137 COVID-19 convalescents and 166 donors of blood and its components were examined. The control group consisted of 50 blood sera collected at the beginning of 2019 and 19 sera collected in 2018 (before the advent of the SARS-CoV-2 virus) and stored at -70 Β°C. Testing was carried out in analytical systems: rapid test βCOVID-19 IgM/IgG Rapid Test (Colloidal Gold)β (China), on an automatic immunochemical analyzer Abbott Architectβ’ i2000 and kit βSARS-CoV2-IgGβ (Abbot, Chicago , IL USA), by the chemiluminescence method using an automatic analyzer of the CL series and kits of the βMindrayβ company (China) βSARS-CoV-2 IgMβ and βSARS-CoV-2 IgGβ and by the enzyme immunoassay method on the kits of the companies βDiagnostic Systemsβ Ltd (Russia, Nizhny Novgorod) βDS-IFA-ANTI-SARS-CoV-2-Gβ, βXemaβ Ltd (Federal State Budgetary Institution βNational Medical Research Center of Hematologyβ of the Ministry of Health of Russia) βSARS-CoV-2-IgG-IFAβ and βVector-Bestβ CJSC (Russia, Novosibirsk)β SARS-COV-2-IgM-IFA-BESTβ and βSARS-COV-2-IgG-IFABESTβ. When comparing the results of testing 137 plasma samples on the Vector-Best and Mindray kits for IgG antibodies, 127 samples were positive, 7 samples were negative on both kits, the discrepancy was 2.2%. In the study of IgM antibodies, 32.1% were positive, and 52.6% were negative in both kits. The discrepancy rate was 15.3%. Out of 166 samples, 1 serum (0.6%) was negative in 5 kits. On the Mindray kit, IgG antibodies to the antigens of the SARS-CoV-2 virus were detected in 165 samples (99.4%), on Vector-Best β in 164 sera (98.8%), on Diagnostic systems β in 151 (90.96%), on Xema β in 154 (92.8%), and on Abbott β in 155 samples (93.4%). At the same time, 135 (81.33%) samples were positive in all kits, while 30 samples had discordant results (18.07%), and in 9 sera, specific IgG was not detected in 2 or more kits. ROC analysis revealed a high diagnostic value of all tested kits (AUC from 0.908 to 0.998), which indicates a high quality of the separation model of positive and negative samples (p < 0.001). With the cut-off set by the manufacturers, the sensitivity and specificity ranged from 82.8% and 93.3% for the Diagnostic Systems kit to 99.4% and 95.8% for the VectorBest kit. The calculated correlation coefficients were higher between kits with a similar composition of the antigen used in the kits; therefore, it is better to monitor the dynamics of antibodies by diagnostic kits from the same manufacturer
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