355 research outputs found

    Dynamic facial expressions of emotions are discriminated at birth

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    The ability to discriminate between different facial expressions is fundamental since the first stages of postnatal life. The aim of this study is to investigate whether 2-days-old newborns are capable to discriminate facial expressions of emotions as they naturally take place in everyday interactions, that is in motion. When two dynamic displays depicting a happy and a disgusted facial expression were simultaneously presented (i.e., visual preference paradigm), newborns did not manifest any visual preference (Experiment 1). Nonetheless, after being habituated to a happy or disgusted dynamic emotional expression (i.e., habituation paradigm), newborns successfully discriminated between the two (Experiment 2). These results indicate that at birth newborns are sensitive to dynamic faces expressing emotions

    Hybrid modeling of a biorefinery separation process to monitor short-term and long-term membrane fouling

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    Membrane filtration is commonly used in biorefineries to separate cells from fermentation broths containing the desired products. However, membrane fouling can cause short-term process disruption and long-term membrane degradation. The evolution of membrane resistance over time can be monitored to track fouling, but this calls for adequate sensors in the plant. This requirement might not be fulfilled even in modern biorefineries, especially when multiple, tightly interconnected membrane modules are used. Therefore, characterization of fouling in industrial facilities remains a challenge. In this study, we propose a hybrid modeling strategy to characterize both reversible and irreversible fouling in multi-module biorefinery membrane separation systems. We couple a linear data-driven model, to provide high-frequency estimates of trans-membrane pressures from the available measurements, with a simple nonlinear knowledge-driven model, to compute the resistances of the individual membrane modules. We test the proposed strategy using real data from the world's first industrial biorefinery manufacturing 1,4-bio-butanediol via fermentation of renewable raw materials. We show how monitoring of individual resistances, even when done by simple visual inspection, offers valuable insight on the reversible and irreversible fouling state of the membranes. We also discuss the advantage of the proposed approach, over monitoring trans-membrane pressures and permeate fluxes, from the standpoints of data variability, effect of process changes, interaction between module in multi-module systems, and fouling dynamics

    The Butterfly Fauna Of The Italian Maritime Alps:Results Of The «Edit» Project

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    Bonelli, Simona, Barbero, Francesca, Casacci, Luca Pietro, Cerrato, Cristiana, Balletto, Emilio (2015): The butterfly fauna of the Italian Maritime Alps: results of the EDIT project. Zoosystema 37 (1): 139-167, DOI: 10.5252/z2015n1a6, URL: http://dx.doi.org/10.5252/z2015n1a

    Diabetes risk reduction diet and endometrial cancer risk

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    Diabetes increases endometrial cancer risk. We investigated the role of a diabetes risk reduction diet (DRRD) on the risk of endometrial cancer using data from a multicentric, Italian hospital-based case–control study (1992–2006) enrolling 454 histologically confirmed cases of endometrial cancer and 908 controls matched by age and center. We derived a DRRD score assigning higher scores for higher intakes of cereal fiber, fruit, coffee, polyunsaturated:saturated fatty acid ratio, and nuts and for lower glycemic load and lower intakes of red/processed meat and sugar-sweetened beverages/fruit juices. The odds ratios (OR) of endometrial cancer according to the DRRD score were derived by multiple conditional logistic regression models. The OR for high (DRRD score >24, i.e., third tertile) versus medium–low adherence to the DRRD was 0.73 (95% confidence interval, CI, 0.55–0.97). Similar results were observed after the exclusion of diabetic women (OR 0.75; 95% CI, 0.56–1.00) and allowance for total vegetable consumption (OR 0.80; 95% CI, 0.60–1.07). Inverse associations were observed in most of the analyzed subgroups. The OR for high DRRD combined with high vegetable consumption was 0.45 (95% CI, 0.28–0.73). Our results suggest that diets able to reduce diabetes risk may also reduce endometrial cancer risk. High vegetable consumption combined with high adherence to the DRRD may provide additional benefit in endometrial cancer prevention

    Adherence to the Mediterranean diet and nasopharyngeal cancer risk in Italy

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    Purpose: Few studies investigated the role of diet on nasopharyngeal cancer (NPC) risk in non-endemic areas. The aim of this study was to assess the association between adherence to the traditional Mediterranean diet and NPC risk in a southern European low-risk population. Methods: We conducted a hospital-based case-control study in Italy, including 198 histologically confirmed NPC cases and 594 matched controls. Dietary habits were collected by means of a validated food-frequency questionnaire, including 83 foods, food groups, or beverages. Adherence to the traditional Mediterranean diet was assessed through a Mediterranean Diet Score (MDS), based on nine dietary components characterizing this dietary profile, i.e., high intake of vegetables, fruits and nuts, cereals, legumes, and fish; low intake of dairy products and meat; high monounsaturated to saturated fatty acid ratio; and moderate alcohol intake. We estimated odds ratios (ORs) of NPC, and the corresponding 95% confidence intervals (CIs), for increasing MDS (i.e., increasing adherence) using multiple logistic regression models, adjusted for major confounding factors. Results: As compared to MDS 64 4, the ORs of NPC were 0.83 (95% CI: 0.54\u20131.25) for MDS of 5 and 0.66 (95% CI: 0.44\u20130.99) for MDS 65 6, with a significant trend of decreasing risk (p 0.043). The corresponding population attributable fraction was 22%, indicating that 22% of NPC cases in this population would be avoided by shifting all subjects to a score 656. Conclusions: Our study supports a favorable role of the Mediterranean diet on NPC risk

    Family history of cancer and the risk of cancer: a network of case-control studies

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    Background The risk of many cancers is higher in subjects with a family history (FH) of cancer at a concordant site. However, few studies investigated FH of cancer at discordant sites. Patients and methods This study is based on a network of Italian and Swiss case-control studies on 13 cancer sites conducted between 1991 and 2009, and including more than 12 000 cases and 11 000 controls. We collected information on history of any cancer in first degree relatives, and age at diagnosis. Odds ratios (ORs) for FH were calculated by multiple logistic regression models, adjusted for major confounding factors. Results All sites showed an excess risk in relation to FH of cancer at the same site. Increased risks were also found for oral and pharyngeal cancer and FH of laryngeal cancer (OR = 3.3), esophageal cancer and FH of oral and pharyngeal cancer (OR = 4.1), breast cancer and FH of colorectal cancer (OR = 1.5) and of hemolymphopoietic cancers (OR = 1.7), ovarian cancer and FH of breast cancer (OR = 2.3), and prostate cancer and FH of bladder cancer (OR = 3.4). For most cancer sites, the association with FH was stronger when the proband was affected at age <60 years. Conclusions Our results point to several potential cancer syndromes that appear among close relatives and may indicate the presence of genetic factors influencing multiple cancer site

    Longer fixation duration while viewing face images

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    The spatio-temporal properties of saccadic eye movements can be influenced by the cognitive demand and the characteristics of the observed scene. Probably due to its crucial role in social communication, it is argued that face perception may involve different cognitive processes compared with non-face object or scene perception. In this study, we investigated whether and how face and natural scene images can influence the patterns of visuomotor activity. We recorded monkeys’ saccadic eye movements as they freely viewed monkey face and natural scene images. The face and natural scene images attracted similar number of fixations, but viewing of faces was accompanied by longer fixations compared with natural scenes. These longer fixations were dependent on the context of facial features. The duration of fixations directed at facial contours decreased when the face images were scrambled, and increased at the later stage of normal face viewing. The results suggest that face and natural scene images can generate different patterns of visuomotor activity. The extra fixation duration on faces may be correlated with the detailed analysis of facial features

    Influência da iluminação e da aeração sobre o crescimento de Chlorella sorokiniana em meio BG11.

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    Representando uns dos principais objetos de estudos atualmente, microalgas são, em geral, microrganismos fotossintetizantes altamente capazes de retirar CO2 atmosférico e gerar biomassa rica em biomoléculas de interesse industrial e comercial. No entanto, para obtenção de altos valores de rendimento e produtividade, condições ideais de crescimento são muito importantes. Diante disso, o objetivo deste trabalho foi comparar a influência de biorreatores, ou modelos utilizados para o cultivo, sobre o crescimento e o rendimento de biomassa de Chlorella sorokiniana em meio BG11 e, também, verificar os resultados que o uso de diferentes luzes pode gerar. Para tanto, foram realizados dois experimentos não simultâneos em que, primeiramente, a cepa foi cultivada em dois módulos de cultivos diferentes: módulo novo (MN), com biorreatores e sistema de aeração novos da sala de microalgas; e módulo antigo (MA), utilizando Erlenmeyers, pipeta estéril para passagem de ar e outros componentes. Em um segundo momento, com o intuito de analisar quais luzes e combinações geram maiores crescimentos e, por conseguinte, maiores biomassas secas finais, as microalgas foram cultivadas sob três condições de iluminação diferentes: luz branca (B), luz branca + luz colorida (B+C) e luz colorida (C). Para os dois módulos, temperatura, aeração e pH também foram por espectrofotometria, contagem de células, leitura de turbidez por OD manual e centrifugação e liofilização das biomassas, para saber o peso de massa seca final, foram feitas. Com isso, as análises e os testes mostraram rendimento de biomassa bem maior em MN em comparação com MA e maior crescimento dos cultivos crescidos sob luz B+C, havendo diferenças significativas em ambos os experimentos. Esses resultados permitiram demonstrar a maior eficiência dos novos módulos de cultivo de microalgas da Embrapa Agroenergia e quais luzes utilizadas geram maiores crescimentos, destacando&#8209;se também a importância de se ter condições de cultivo adequadas
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