Crystallographic studies of gas sorption in metal-organic frameworks.

Metal-organic frameworks (MOFs) are a class of porous crystalline materials of modular design. One of the primary applications of these materials is in the adsorption and separation of gases, with potential benefits to the energy, transport and medical sectors. In situ crystallography of MOFs under gas atmospheres has enabled the behaviour of the frameworks under gas loading to be investigated and has established the precise location of adsorbed gas molecules in a significant number of MOFs. This article reviews progress in such crystallographic studies, which has taken place over the past decade, but has its origins in earlier studies of zeolites, clathrates etc. The review considers studies by single-crystal or powder diffraction using either X-rays or neutrons. Features of MOFs that strongly affect gas sorption behaviour are discussed in the context of in situ crystallographic studies, specifically framework flexibility, and the presence of (organic) functional groups and unsaturated (open) metal sites within pores that can form specific interactions with gas molecules

Does digital imaging decrease patient dose? A pilot study and review of the literature

The potential for decreasing patient dose is one of the main arguments for the justification of the cost of digital imaging equipment. However, the literature review with respect to patient doses using digital imaging modalities, presents conflicting results. During this study, patients' entrance surface doses were measured for three simple radiographic examinations, in European centres equipped with a computed radiography digital system. Results showed that doses between centres varied from 30% for chest LAT to 250% for chest PA examination. With the digital image quality criteria still under discussion, and with the post-processing parameters and/or image documentations varying, any dose comparisons between conventional/digital systems, as well as dose comparisons between different centre using digital units, are difficult. Clinical trials are required in order to define reference levels associated with quality of digital image necessary to address specific clinical requirements. © 2006 Oxford University Press