Time-to-Degree: Bachelor’s Degree Completion for Latine First-Year and Transfer Students

Latine bachelor’s degree completion has grown in the last several decades but has not kept pace with other racial and ethnic groups. Millions of Latines have successfully navigated higher education, yet not enough is known about the conduits and barriers to timely degree completion. This dissertation utilizes LatCrit, Anti-Deficit Achievement, and Intersectionality as theoretical frameworks; employs secondary analysis of a City University of New York dataset; and utilizes hierarchical regression modeling to examine the relative impact of college completion programs, academic momentum, and key demographic variables on time-to-degree for Latine students. Further, to see how these relationships operate differently for transfer versus first-year students, analysis was conducted for those two groups separately. The findings revealed that the domains under investigation have varying effects on the time it takes Latines to earn their bachelor’s degrees. Participation in college completion programs, for example, has varying effects on time-to-degree depending on the types of support provided by the program and the student\u27s matriculation status. Furthermore, achieving certain academic momentum milestones, such as attempting 15 credits in semester one, affects Latine first-year students\u27 time-to-degree but has no effect on Latine transfers\u27 time to degree. Finally, the impact of demographic characteristics like citizenship, language, and socioeconomic status vary according to students’ entry point into a bachelor’s degree. Given the findings, recommendations are provided for families, universities, and policymakers to improve Latine bachelor’s degree outcomes

A Self-Assessment Approach to Understanding 4-H Professional Development Needs in the Northeast

In 2017, the National 4-H professional research, knowledge, and competencies (PRKC) taxonomy was updated reflecting the current needs of 4-H youth development professionals. Knowledge and skill gaps of 4-H professionals need to be identified to optimize resource allocation for professional development on the state and regional level. We developed a web-based self-assessment of the PRKC tool using Qualtrics, that evaluated the core competencies across the 6 PRKC domains: (a) youth development; (b) youth program development; (c) volunteerism; (d) equity, access, and opportunity; (e) partnerships; and (f) organizational systems. The responses from 188 Extension 4-H professionals (approximately a quarter of the 4-H Extension professionals in the Northeast region) were analyzed to (a) identify the knowledge and skills gaps in competencies within 6 domains, and (b) provide suggestions for professional development that would be of value to each state or region, based on the aggregate data. The results show respondents perceived their personal knowledge, skills, and competencies highest in the domains of access, equity, and opportunity and organizational systems. The domains with the lowest perceived personal effectiveness were youth program development and volunteerism. Not surprisingly, the aggregate results indicate that respondents with a greater number of years of experience in Extension reported higher competency in three domains (youth program development, volunteerism, and organizational systems). This tool can be utilized by Extension at any level to better understand the needs of the 4-H professional workforce. Results can aid the design of professional development opportunities to meet the knowledge and skill gaps identified among respondents

Development and Testing of Program Evaluation Instruments for the iCook 4-H Curriculum

Objective: To develop and test the validity of program outcome evaluation instruments for cooking, eating, and playing together for obesity prevention during iCook 4-H. Design: Instrument development for both youth and adults through pre-post testing of items newly constructed and compiled to address key curriculum constructs. Testing occurred throughout program intervention and dissemination to determine dimensionality, internal consistency and test-retest reliability, and validity. Setting: A 5-state out-of-school program in cooperative extension and other community sites. Participants: Youths aged 9−10 years; adults were main food preparers; the first phase involved 214 dyads and the second phase, 74 dyads. Main Outcome Measure(s): Youth measures were cooking skills, culinary self-efficacy, physical activity, and openness to new foods. Adult measures were cooking together, physical activity, and eating together. Analysis: Exploratory factor analysis to determine initial scale structure and confirmatory factor analysis to confirm factor structures. Longitudinal invariance tests to see whether the factor structure held over time. Test-retest reliability was determined by Pearson r and internal consistency was determined by coefficient V and Cronbach a. Validity testing was determined by Pearson r correlations. Results: Youth cooking skills, openness to new foods, and adult eating together and cooking together showed strong evidence for dimensionality, reliability, and validity. Youth physical activity and adult physical activity measures showed strong evidence for dimensionality and validity but not reliability. The youth culinary selfefficacy measure showed strong evidence for reliability and validity but weaker evidence for dimensionality. Conclusions and Implications: Program outcome evaluation instruments for youths and adults were developed and tested to accompany the iCook 4-H curriculum. Program leaders, stakeholders, and administrators may monitor outcomes within and across programs and generate consistent reporting

Development and Testing of Program Evaluation Instruments for the iCook 4-H Curriculum

Objective To develop and test the validity of program outcome evaluation instruments for cooking, eating, and playing together for obesity prevention during iCook 4-H. Design Instrument development for both youth and adults through pre-post testing of items newly constructed and compiled to address key curriculum constructs. Testing occurred throughout program intervention and dissemination to determine dimensionality, internal consistency and test-retest reliability, and validity. Setting A 5-state out-of-school program in cooperative extension and other community sites. Participants Youths aged 9–10 years; adults were main food preparers; the first phase involved 214 dyads and the second phase, 74 dyads. Main Outcome Measure(s) Youth measures were cooking skills, culinary self-efficacy, physical activity, and openness to new foods. Adult measures were cooking together, physical activity, and eating together. Analysis Exploratory factor analysis to determine initial scale structure and confirmatory factor analysis to confirm factor structures. Longitudinal invariance tests to see whether the factor structure held over time. Test-retest reliability was determined by Pearson r and internal consistency was determined by coefficient Ω and Cronbach α. Validity testing was determined by Pearson rcorrelations. Results Youth cooking skills, openness to new foods, and adult eating together and cooking together showed strong evidence for dimensionality, reliability, and validity. Youth physical activity and adult physical activity measures showed strong evidence for dimensionality and validity but not reliability. The youth culinary self-efficacy measure showed strong evidence for reliability and validity but weaker evidence for dimensionality. Conclusions and Implications Program outcome evaluation instruments for youths and adults were developed and tested to accompany the iCook 4-Hcurriculum. Program leaders, stakeholders, and administrators may monitor outcomes within and across programs and generate consistent reporting

Optical Coherence Tomography (OCT) for examination of artworks

Chapter in the book: Bastidas D., Cano E. (eds) Advanced Characterization Techniques, Diagnostic Tools and Evaluation Methods in Heritage Science. Springer, Cham, 2018, pp 49-59 , doi: 10.1007/978-3-319-75316-4, Authors’version after embargo periodOptical coherence tomography is a fast, non-invasive technique of structural analysis utilising near-infrared radiation. Examples of using OCT, for obtaining cross-sectional images of objects of craftsmanship and an easel painting have been shown. Issues regarding the technique of execution and destruction phenomena were resolved non-invasively. In some cases, the secondary alterations can be identified and localised within the object’s structure which helps in authentication of the artwork

Early-onset Amyloid Deposition and Cognitive Deficits in Transgenic Mice Expressing a Double Mutant Form of Amyloid Precursor Protein 695

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Critical assessment of the elemental composition of Corning archeological reference glasses by LA-ICP-MS

Corning archeological reference glasses A, B, C, and D have been made to simulate different historic technologies of glass production and are used as standards in historic glass investigations. In this work, nanoseconds (193, 266 nm) and femtosecond (800 nm) laser ablation were used to study the elemental composition of Corning glasses using laser ablation inductively coupled plasma mass spectrometry. The determined concentrations of 26 oxides (Li2O, B2O3, Na2O, MgO, Al2O3, SiO2, P2O5, K2O, CaO, TiO2, V2O5, Cr2O3, MnO, Fe2O3, CoO, NiO, CuO, ZnO, Rb2O, SrO, ZrO2, SnO2, Sb2O5, BaO, PbO, Bi2O3) are compared with values reported in the literature. Results show variable discrepancies between the data, with the largest differences found for Cr2O3 in Corning A; Li2O, B2O3, and Cr2O3 in Corning B; and MnO, Sb2O5, Cr2O3, and Bi2O3 in Corning C. The best agreement between the measured and literature values was found for Corning D. However, even for this reference, glass re-evaluation of the data was necessary and new values for PbO, BaO, and Bi2O3 are proposed

Regulation of early steps of GPVI signal transduction by phosphatases: a systems biology approach

We present a data-driven mathematical model of a key initiating step in platelet activation, a central process in the prevention of bleeding following Injury. In vascular disease, this process is activated inappropriately and causes thrombosis, heart attacks and stroke. The collagen receptor GPVI is the primary trigger for platelet activation at sites of injury. Understanding the complex molecular mechanisms initiated by this receptor is important for development of more effective antithrombotic medicines. In this work we developed a series of nonlinear ordinary differential equation models that are direct representations of biological hypotheses surrounding the initial steps in GPVI-stimulated signal transduction. At each stage model simulations were compared to our own quantitative, high-temporal experimental data that guides further experimental design, data collection and model refinement. Much is known about the linear forward reactions within platelet signalling pathways but knowledge of the roles of putative reverse reactions are poorly understood. An initial model, that includes a simple constitutively active phosphatase, was unable to explain experimental data. Model revisions, incorporating a complex pathway of interactions (and specifically the phosphatase TULA-2), provided a good description of the experimental data both based on observations of phosphorylation in samples from one donor and in those of a wider population. Our model was used to investigate the levels of proteins involved in regulating the pathway and the effect of low GPVI levels that have been associated with disease. Results indicate a clear separation in healthy and GPVI deficient states in respect of the signalling cascade dynamics associated with Syk tyrosine phosphorylation and activation. Our approach reveals the central importance of this negative feedback pathway that results in the temporal regulation of a specific class of protein tyrosine phosphatases in controlling the rate, and therefore extent, of GPVI-stimulated platelet activation

The thrombotic potential of oral pathogens

In recent times the concept of infectious agents playing a role in cardiovascular disease has attracted much attention. Chronic oral disease such as periodontitis, provides a plausible route for entry of bacteria to the circulation. Upon entry to the circulation, the oral bacteria interact with platelets. It has been proposed that their ability to induce platelet aggregation and support platelet adhesion is a critical step in the pathogenesis of the infection process. Many published studies have demonstrated multiple mechanisms through which oral bacteria are able to bind to and activate platelets. This paper will review the various mechanisms oral bacteria use to interact with platelets