4,315 research outputs found
The causes for geographical variations in OS187/OS186 at the Cretaceous-Tertiary boundary
Researchers at Yale has approached the problem of the osmium isotopic composition of marine deposits formed in contact with both oxidized and reduced bottom waters. The measured (187) Os/(186) Os ratios of modern bulk sediment can be explained using mixing equations involving continental detrital, volcaniclastic, cosmogenic and hydrogeneous components. These studies show that sediments deposited under reducing marine conditions contain a hydrogenous component which is enriched in Re and has a radiogenic (187) Os/(186) Os ratio. The presence of such a hydrogenous component in the marine fish clay at Stevns Klint can account for the elevation of its (187) Os/(186) Os ration above the expected meteoritic value. Mass balance considerations require the Re/Os ratio of the phase precipitated from the terminal Cretaceous sea at Stevns Klint to have been about one tenth the value observed in contemporary deposits in the Black Sea, assuming Re has not been lost (or Os gained) subsequent to precipitation. In continental sections, the elevation of the (187) Os/(186) Os ratio in boundary layers may be due to precipitation from continental waters of crustally-derived radiogenic osmium either contemporaneous with the meteoritic (or mantle) osmium deposition or later during diagenesis
Does Global Health Funding Respond to Recipients’ Needs? Comparing Public and Private Donors’ Allocations in 2005–2007
Adding to official development assistance (ODA), private foundations have emerged as important donors to the global health agenda. Amid this increasing funder diversity and growing global health budgets, responsiveness to recipients’ needs is a central concern. Merging datasets on ODA flows in 2005–07, over 2,800 foundation grants, disease burden, and perceived priorities in 27 low- and middle-income countries, this study offers the first comprehensive national-level analysis of global health aid responsiveness. The analysis shows that national patterns of disease burden explain neither public nor private aid flows during this period. While ODA committed during these years was weakly yet significantly correlated with health priorities, private grants’ responsiveness was even weaker and did not achieve ODA significance levels either
Feeding practices and nutritional status of HIV-exposed and HIV-unexposed infants in the Western Cape
Background: Optimal infant- and young child–feeding practices are crucial for nutritional status, growth, development, health and, ultimately, survival. Human breast milk is optimal nutrition for all infants. Complementary food introduced at the correct age is part of optimal feeding practices. In South Africa, widespread access to antiretrovirals and a programme to prevent mother-to-child transmission of HIV have reduced HIV infection in infants and increased the number of HIV-exposed uninfected (HEU) infants. However, little is known about the feeding practices and nutritional status of HEU and HIV-unexposed (HU) infants.Objective: To assess the feeding practices and nutritional status of HIV-exposed and HIV-unexposed (HU) infants in the Western Cape.Design: Prospective substudy on feeding practices nested in a pilot study investigating the innate immune abnormalities in HEU infants compared to HU infants. The main study commenced at week 2 of life with the nutrition component added from 6 months. Information on children’s dietary intake was obtained at each visit from the caregiver, mainly the mother. Head circumference, weight and length were recorded at each visit. Data were obtained from 6-, 12- and 18-month visits. World Health Organization feeding practice indicators and nutrition indicators were utilised.Setting: Tygerberg Academic Hospital, Western Cape. Mothers were recruited from the postnatal wards.Subjects: Forty-seven mother–infant pairs, 25 HEU and 22 HU infants, participated in this nutritional substudy. Eight (17%) infants, one HU and seven HEU, were lost to follow-up over the next 12 months. The HEU children were mainly Xhosa (76%) and HU were mainly mixed race (77%).Results: The participants were from poor socio-economic backgrounds. In both groups, adherence to breastfeeding recommendations was low with suboptimal dietary diversity. We noted a high rate of sugar- and salt-containing snacks given from a young age. The HU group had poorer anthropometric and nutritional indicators not explained by nutritional factors alone. However, alcohol and tobacco use was much higher amongst the HU mothers.Conclusion: Adherence to breastfeeding recommendations was low. Ethnicity and cultural milieu may have influenced feeding choices and growth. Further research is needed to understand possible reasons for the poorer nutritional and anthropometric indicators in the HU group
Test of renormalization predictions for universal finite-size scaling functions
We calculate universal finite-size scaling functions for systems with an
n-component order parameter and algebraically decaying interactions. Just as
previously has been found for short-range interactions, this leads to a
singular epsilon-expansion, where epsilon is the distance to the upper critical
dimension. Subsequently, we check the results by numerical simulations of spin
models in the same universality class. Our systems offer the essential
advantage that epsilon can be varied continuously, allowing an accurate
examination of the region where epsilon is small. The numerical calculations
turn out to be in striking disagreement with the predicted singularity.Comment: 6 pages, including 3 EPS figures. To appear in Phys. Rev. E. Also
available as PDF file at
http://www.cond-mat.physik.uni-mainz.de/~luijten/erikpubs.htm
inbreedR: An R package for the analysis of inbreeding based on genetic markers
1. Heterozygosity fitness correlations (HFCs) have been used extensively to explore the impact of inbreeding on individual fitness. Initially, most studies used small panels of microsatellites, but more recently with the advent of next generation sequencing, large SNP datasets are becoming increasingly available and these provide greater power and precision to quantify the impact of inbreeding on fitness. 2. Despite the popularity of HFC studies, effect sizes tend to be rather small. One reason for this may be a low variation in inbreeding level across individuals. Using genetic markers, it is possible to measure variance in inbreeding through the strength of correlation in heterozygosity across marker loci, termed identity disequilibrium (ID). 3. ID can be quantified using the measure g2 which is also a central parameter in HFC theory that can be used within a wider framework to estimate the direct impact of inbreeding on both marker heterozygosity and fitness. However, no software exists to calculate g2 for large SNP datasets nor to implement this framework. 4. inbreedR is an R package that provides functions to calculate g2 based on microsatellite and SNP markers with associated p-values and confidence intervals. Within the framework of HFC theory, inbreedR also estimates the impact of inbreeding on marker heterozygosity and fitness. Moreover, we implemented easy-to-use simulations to explore the precision and magnitude of estimates based on different numbers of genetic markers. We hope this package will facilitate good practice in the analysis of HFCs and help to deepen our understanding of inbreeding effects in natural populations
Dimensional crossover in dipolar magnetic layers
We investigate the static critical behaviour of a uniaxial magnetic layer,
with finite thickness L in one direction, yet infinitely extended in the
remaining d dimensions. The magnetic dipole-dipole interaction is taken into
account. We apply a variant of Wilson's momentum shell renormalisation group
approach to describe the crossover between the critical behaviour of the 3-D
Ising, 2-d Ising, 3-D uniaxial dipolar, and the 2-d uniaxial dipolar
universality classes. The corresponding renormalisation group fixed points are
in addition to different effective dimensionalities characterised by distinct
analytic structures of the propagator, and are consequently associated with
varying upper critical dimensions. While the limiting cases can be discussed by
means of dimensional epsilon expansions with respect to the appropriate upper
critical dimensions, respectively, the crossover features must be addressed in
terms of the renormalisation group flow trajectories at fixed dimensionality d.Comment: 25 pages, Latex, 12 figures (.eps files) and IOP style files include
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