Measuring Drivers of Procrastination in Academic Student

Abstract. Procrastination is the lack or absence of self-regulated performance and the tendency to deny or completely avoid an activity under one’s control (Tuckman & Sexton, 1989). MARS, also known as model of individual behavior, are model used to understand on what drivers can form an individual behavior. It consist of four factors which are motivation, ability, role perceptions, and support/situational factors).As an organization, academic institution need to know the drivers of behavior that might affect their academic members performance, including student. By creating a Procrastination Scale to measure procrastination level and Academic Motivation Scale into MARS model this research gather a 116 sample of academic student in SBM ITB. The result shows that Amotivation (r=.187) and Motivation External of external regulation (r=.197) has positive correlation with procrastination level. Using hierarchical regression analysis, the result further show that amotivation (b=.197) act as the most dominant contributor to procrastination level. External Motivation  of external regulation (b=.126) follows as the second contributor while Situational Factors (b=-.127) shows as counter contributer of procrastination. As organization SBM ITB might want to further motivate their student and give tutoring about managing academic and non-academic activities. SBM ITB might also want to maintain their support to students to avoid further problem about increasing procrastination level. Keyword: motivation, ability, role perception, situational factor, procrastination, academic, organizatio

Tumoricidal effect of skeletal vibratory signal during Al-Fatihah recitation on human cancer cells

This research attempts to study if physical vibration generated in the human body during recitation of AIFatihah has an effect on cancer cells. This includes working sequentially on two main objectives. The first objective is to measure and model skin vibration signals using accelerometer (skin acceleration level) on a cohort of verified reciters whereby measurement is carried out during recitation. Subsequently the modeled vibration is simulated on cancer cells (NCI H929: Myeloma) and its growth and viability assessed. At the time of this final report the first objective was not achieved hence prevented progression to the second objective. A cohort of 15 reciters has been established but we could not proceed to gauge skin acceleration level as currently available methods were found to be unreliable. Current methods of mounting accelerometer to the skin produce highly variable acceleration amplitudes. Various alternatives were devised and attempted, such as using polystyrene, plastic holders etc failed to fulfil gage repeatability and reproducibility criteria. Towards the end, preliminary gage study using suction cups as accelerometer mounting adapter showed promise but the final measurement analysis is yet to be carried out. This research is still ongoing in spite of the end of study period

Validation of international prognostic index for non-hodgkin's lymphoma in northeast Peninsular Malaysian Malays

Indeks Prognosis Antarabangsa {IPI) telah diketengahkan untuk menstratumkan risiko pesakit limfoma bukan Hodgkin (NHL) dan mengenalpasti subset pesakit berisiko tinggi yang mungkin tidak dapat bertindakbalas terhadap kemoterapi dengan memuaskan. IPI telah dibentuk berlandaskan model populasi pesakit berbangsa barat. Kami telah menlaksanakan suatu kajian longitudinal melibatkan pesakit NHL aggresif yang menerima rawatan di Hospital USM dari I haribulan J anuari 1990 ke 31 haribulan Disember 2000. Kajian ini hanya melibatkan pesakit berbangsa Melayu. Ini bertujuan untuk menguji kesesuaian penggunaan IPI ke atas etnik tersebut. Ciri-ciri klinikal sepertimana yang telah diuji dalam model IPI yang asal, telah diuji ke atas kohort kami. Pencapaian pesakit dari segi kadar respons sempurna (complete response rate : CR), kadar kemandirian keseluruhan (overall survival rate: OS) dan kadar kemandirian bebas penyakit (disease free survival rate: DFS) bagi setiap faktor eli atas telah eli olah. Pada masa yang sama data-data yang diperolehi telah digunakan untuk membentuk profit penyakit NHL dalam populasi kami. International prognostic index (IPI) was introduced to risk stratify non-Hodgkin lymphoma (NHL) patients and to identify high-risk patient who might not respond favorably to standard chemotherapy. IPI was modeled from a Caucasian based patient population. We undertook a single center, observational longitudinal study involving all available patients with aggressive NHL who had received treatment from Hospital USM between 1st Jan 1990 and 31st Dec 2000. We confined our study to adult Malay patients to test the applicability of IPI in this racial group. Individual presenting clinical features was categorized as in the IPI study, and the patients' outcome in terms of complete response (CR), overall survival (OS) and disease free survival (DFS) rates for each of the above features were determined. At the same time the available data was used to characterize NHL disease profile in our patient population

Evidence-Based Guidelines for Empirical Therapy of Neutropenic Fever in Korea

Neutrophils play an important role in immunological function. Neutropenic patients are vulnerable to infection, and except fever is present, inflammatory reactions are scarce in many cases. Additionally, because infections can worsen rapidly, early evaluation and treatments are especially important in febrile neutropenic patients. In cases in which febrile neutropenia is anticipated due to anticancer chemotherapy, antibiotic prophylaxis can be used, based on the risk of infection. Antifungal prophylaxis may also be considered if long-term neutropenia or mucosal damage is expected. When fever is observed in patients suspected to have neutropenia, an adequate physical examination and blood and sputum cultures should be performed. Initial antibiotics should be chosen by considering the risk of complications following the infection; if the risk is low, oral antibiotics can be used. For initial intravenous antibiotics, monotherapy with a broad-spectrum antibiotic or combination therapy with two antibiotics is recommended. At 3-5 days after beginning the initial antibiotic therapy, the condition of the patient is assessed again to determine whether the fever has subsided or symptoms have worsened. If the patient's condition has improved, intravenous antibiotics can be replaced with oral antibiotics; if the condition has deteriorated, a change of antibiotics or addition of antifungal agents should be considered. If the causative microorganism is identified, initial antimicrobial or antifungal agents should be changed accordingly. When the cause is not detected, the initial agents should continue to be used until the neutrophil count recovers

Liberalisasi kewangan dan kecekapan kos perbankan Islam dan konvensional: Pendekatan analisis sempadan stokastik

Kertas ini menganalisis kecekapan bank komersial di Malaysia semasa proses liberalisasi kewangan menggunakan analisis sempadan stokastik dengan tumpuan kertas adalah terhadap kecekapan bank islam asing dan bank konvensional yang mempunyai subsidiari bank islam. Keputusan menunjukkan bahawa bank konvensional domestik yang menjalankan operasi perbankan islam mempunyai teknologi yang menjimatkan kos berbanding bank-bank lain,. Walau bagaimanapun, bank islam asing yang agak baru beroperasi mungkin memerlukan lebih masa lagi untuk bersaing kerana didapati kurang cekap, Manakala bank konvensional yang mempunyai subsidiari bank islam pula tidak menunjukkan kesan pembaikan kecekapan bagi tempoh sampel.Oleh itu dasar kerajaan untuk meningkatkan kecekapan bank diMalaysia terutama bank domestik melalui kemasukan bank islam asing dan kemunculan bank islam subsidiari bagi tempoh sampel masih lagi belum tercapai bagi tempoh sampel

Bleeding outcome during a dengue outbreak in 2005 in the East-coast region of Peninsular Malaysia: a prospective study

During a dengue outbreak in 2005 in the East-coast region of Peninsular Malaysia, one of the worst hit areas in the country at that time, we undertook a prospective study. We aimed to describe the bleeding outcome and changes in the liver and hematologic profiles that were associated with major bleeding outcome during the outbreak. All suspected cases of dengue admitted into the only referral hospital in the region during the outbreak were screened for WHO 2002 criteria and serology. Liver function, hematologic profile and severity of bleeding outcome were carefully documented. The association between symptoms, liver and hematologic impairments with the type of dengue infection (classical vs. hemorrhagic) and bleeding outcome (major vs. non-major) was tested. Dengue fever was confirmed in 183 cases (12.5/100,000 population) and 144 cases were analysed. 59.7% were dengue hemorrhagic fever, 3.5% were dengue shock syndrome and there were 3 in-hospital deaths. Major bleeding outcome (gastrointestinal bleeding, intracranial bleeding or haemoptysis) was present in 14.6%. Elevated AST, ALT and bilirubin were associated with increasing severity of bleeding outcome (all P < 0.05). Platelet count and albumin level were inversely associated with increasing severity of bleeding outcome (both P < 0.001). With multivariable analysis, dengue hemorrhagic fever was more likely in the presence of abdominal pain (OR 1.1, 95% CI 0.02- 1.6) and elevated AST (OR 1.0, 95% CI 1.0-1.1) but the presence of pleural effusion (OR 5.8, 95% CI: 1.1-29.9) and elevated AST (OR 1.008, 95% CI: 1.005-1.01) predicted a severe bleeding outcome. As a conclusion, the common presence of a severe hemorrhagic form of dengue fever may explain the rising death toll in recent outbreaks and the worst impairment in liver and hematologic profiles was seen in major bleeding outcome

A Review on Secondary Immune Thrombocytopenia in Malaysia

Immune thrombocytopenia (ITP) is an acquired autoimmune disease that occurs in adults and children. In Malaysia, the clinical practice guideline (CPG) for the management of ITP was issued in 2006, which focused almost exclusively on primary ITP (pITP), and only a few secondary ITP (sITP) forms were addressed. All published (twenty-three) sITP articles among children and adults in Malaysia, identified on the academic databases were retrieved. The articles were published between 1981 and 2019, at a rate of 0.62 publications per year. The publications were considered low and mainly focused on rare presentation and followed-up of secondary diseases. This review revealed that sITP in Malaysia is commonly associated with autoimmune diseases (Evan’s syndrome, SLE and WAS), malignancy (Kaposi’s sarcoma and breast cancer) and infection (dengue haemorrhagic fever, Helicobacter pylori and hepatitis C virus). The relationship between ITP and autoimmune diseases, malignancy and infections raise the question concerning the mechanism involved in these associations. Further studies should be conducted to bridge the current knowledge gap, and the further information is required to update the existing CPG of management of ITP in Malaysia

Contribution of BCR-ABL kinase domain mutations to imatinib mesylate resistance in Philadelphia chromosome positive Malaysian chronic myeloid leukemia patients

Development of resistance to imatinib mesylate (IM) in chronic myeloid leukemia (CML) patients is mediated by different mechanisms that can be classified as <em>BCR-ABL</em> dependent or <em>BCR-ABL</em> independent pathways. <em>BCR-ABL</em> dependent mechanisms are most frequently associated with point mutations in tyrosine kinase domain (TKD) of <em>BCR-ABL1</em> and also with <em>BCR-ABL</em> gene amplification. Many different types and frequencies of mutations have been reported in different studies, probably due to the different composition of study cohorts. Since no reports are available from Malaysia, this study was undertaken to investigate the frequency and pattern of <em>BCR-ABL</em> kinase domain mutations using dHPLC followed by sequencing, and also status of <em>BCR-ABL</em> gene amplification using fluorescence <em>in situ</em> hybridization (FISH) on 40 IM resistant Malaysian CML patients. Mutations were detected in 13 patients (32.5%). Five different types of mutations (T315I, E255K, Y253H, M351T, V289F) were identified in these patients. In the remaining 27 IM resistant CML patients, we investigated the contribution made by <em>BCR-ABL</em> gene amplification, but none of these patients showed amplification. It is presumed that the mechanisms of resistance in these 27 patients might be due to<em> BCR-ABL</em> independent pathways. Different mutations confer different levels of resistance and, therefore, detection and characterization of TKD mutations is highly important in order to guide therapy in CML patients

Antileukemic Effect of Tualang Honey on Acute and Chronic Leukemia Cell Lines

Complementary medicine using natural product as antitumor is on the rise. Much research has been performed on Tualang Honey and it was shown to have therapeutic potential in wound healing, and antimicrobial activity and be antiproliferative against several cancer models such as human osteosarcoma (HOS), human breast (MCF-7 and MDA-MB-231), and cervical (HeLa) cancer cell lines. To date, there was limited study on antileukemic properties of Tualang (Koompassia excelsa) Honey. The aim of this study was to evaluate the antileukemic effect of Tualang Honey on acute and chronic leukemia cell lines. Leukemia cell lines (K562 and MV4-11) and human mononuclear cell isolated from peripheral blood were grown in RPM1 1640 culture medium. The cells were incubated with increasing concentrations of Tualang Honey. After incubation, the evaluation of viability and apoptosis was performed. The morphological changes of leukemia cells were the presence of cytoplasmic blebs followed by apoptotic bodies and round shape of cells. IC50 against K562 and MV4-11 was determined. Tualang Honey gave 53.9% and 50.6% apoptosis activity on K562 and MV4-11, respectively, while on human mononuclear cell it was 37.4%. Tualang Honey has the apoptosis-inducing ability for acute and chronic myeloid leukemia (K562 and MV4-11) cell lines