13 research outputs found
Ătude descriptive des rĂ©seaux sociaux des personnes prĂ©sentant une dĂ©ficience intellectuelle lĂ©gĂšre ou modĂ©rĂ©e ĂągĂ©es de 16 Ă 65 ans
Impact of high atmospheric carbon dioxide on the biotic stress response of the model cereal species Brachypodium distachyon
Losses due to disease and climate change are among the most important issues currently facing crop production. It is therefore important to establish the impact of climate change, and particularly of high carbon dioxide (hCO2), on plant immunity in cereals, which provide 60% of human calories. The aim of this study was to determine if hCO2 impacts Brachypodium distachyon immunity, a model plant for temperate cereals. Plants were grown in air (430 ppm CO2) and at two high CO2 conditions, one that is relevant to projections within the coming century (1000 ppm) and a concentration sufficient to saturate photosynthesis (3000 ppm). The following measurements were performed: phenotyping and growth, salicylic acid contents, pathogen resistance tests, and RNAseq analysis of the transcriptome. Improved shoot development was observed at both 1000 and 3000 ppm. A transcriptomic analysis pointed to an increase in primary metabolism capacity under hCO2. Alongside this effect, up-regulation of genes associated with secondary metabolism was also observed. This effect was especially evident for the terpenoid and phenylpropanoid pathways, and was accompanied by enhanced expression of immunity-related genes and accumulation of salicylic acid. Pathogen tests using the fungus Magnaporthe oryzae revealed that hCO2 had a complex effect, with enhanced susceptibility to infection but no increase in fungal development. The study reveals that immunity in B. distachyon is modulated by growth at hCO2 and allows identification of pathways that might play a role in this effect
Impact of high atmospheric carbon dioxide on the biotic stress response of the model cereal species Brachypodium distachyon
International audienceLosses due to disease and climate change are among the most important issues currently facing crop production. It is therefore important to establish the impact of climate change, and particularly of high carbon dioxide (hCO 2 ), on plant immunity in cereals, which provide 60% of human calories. The aim of this study was to determine if hCO 2 impacts Brachypodium distachyon immunity, a model plant for temperate cereals. Plants were grown in air (430 ppm CO 2 ) and at two high CO 2 conditions, one that is relevant to projections within the coming century (1000 ppm) and a concentration sufficient to saturate photosynthesis (3000 ppm). The following measurements were performed: phenotyping and growth, salicylic acid contents, pathogen resistance tests, and RNAseq analysis of the transcriptome. Improved shoot development was observed at both 1000 and 3000 ppm. A transcriptomic analysis pointed to an increase in primary metabolism capacity under hCO 2 . Alongside this effect, up-regulation of genes associated with secondary metabolism was also observed. This effect was especially evident for the terpenoid and phenylpropanoid pathways, and was accompanied by enhanced expression of immunity-related genes and accumulation of salicylic acid. Pathogen tests using the fungus Magnaporthe oryzae revealed that hCO 2 had a complex effect, with enhanced susceptibility to infection but no increase in fungal development. The study reveals that immunity in B. distachyon is modulated by growth at hCO 2 and allows identification of pathways that might play a role in this effect
A teoria das relaçÔes sociais de sexo: um quadro de anålise sobre a dominação masculina
Droits et voix / Rights and Voices
This volume commemorates the 40th anniversary of the University of Ottawaâs Department of Criminology, founded in 1968. It relates the history of the department from its origins to today, focusing on the theoretical debates that have influenced its critical and self reflexive approach to criminology. The contributions to this volume continue in that vein by questioning the traditional perspective of criminology on a variety of topics including police studies, mental health, political violence, suicide, and crime prevention. Rights and Voices reveals the significant role that the University of Ottawa has played in redefining criminology to advocate activism, social justice, and compassion.Cet ouvrage souligne le 40e anniversaire du DĂ©partement de criminologie de lâUniversitĂ© dâOttawa, fondĂ© en 1968. On y relate lâhistoire du dĂ©partement de ses origines Ă nos jours en mettant lâaccent sur les dĂ©bats thĂ©oriques qui ont influencĂ© son approche critique et autorĂ©flexive de la criminologie. Les articles qui le composent sâinscrivent dans cet ordre dâidĂ©e en mettant en question la perspective traditionnelle de la criminologie sur divers sujets, notamment les Ă©tudes policiĂšres, la santĂ© mentale, la violence politique, le suicide et la prĂ©vention du crime. Droits et voix souligne le rĂŽle primordial que joue lâUniversitĂ© dâOttawa dans la redĂ©finition de la criminologie et la promotion du militantisme, de la justice sociale et de la compassion.Ce recueil cĂ©lĂšbre les quarante ans de vie du DĂ©partement de criminologie de lâUniversitĂ© dâOttawa. Câest pourquoi il est dĂ©diĂ© Ă toutes les personnes qui ont contribuĂ© Ă en faire ce quâil est aujourdâhui : celles qui y ont dirigĂ©, enseignĂ©, supervisĂ©, administrĂ©, Ă©tudiĂ© et cherchĂ©
Sarcomas in patients over 90: Natural history and treatmentâA nationwide study over 6 years
International audienceSoft tissue sarcomas (STS) are rare tumors accounting for less than 1% of human cancers. While the highest incidence of sarcomas is observed in elderly, this population is often excluded or poorly represented in clinical trials. The present study reports on clinicopathological presentation, and outcome of sarcoma patients over 90 recorded in the Netsarc.org French national database. NETSARC (netsarc.org) is a network of 26 reference sarcoma centers with specialized multidisciplinary tumor board (MDTB), funded by the French National Cancer Institute to improve the outcome of sarcoma patients. Since 2010, presentation to an MDTB, second pathological review, and collection of sarcoma patient characteristics and follow-up are collected in a database Information of patients registered from January 1, 2010, to December 31, 2016, in NETSARC were collected, analyzed and compared to the younger population. Patients with sarcomas aged >90 have almost exclusively sarcomas with complex genomics (92.0% vs. 66.3%), are less frequently metastatic (5.3% vs. 14·7%) at diagnosis, have more often superficial tumors (39.8% vs. 14.7%), as well as limbs and head and neck sites (75.2% vs. 38.7%) (all pâ<â0.001). Optimal diagnostic procedures and surgery were less frequently performed in patients over 90 (pâ<â0.001). These patients were less frequently operated in NETSARC centers, as compared to those of younger age groups including aged 80-90. However, local relapse-free survival, metastatic relapse-free survival and relapse-free survival were not significantly different from those of younger patients, in the whole cohort, as well as in the subgroup of operated patients. As expected overall survival was worse in patients over 90 (pâ<â0.001). Patients over 90 who were not operated had worse overall survival than younger patients (9.9 vs. 27.3 months, pâ<â0.001). Patients with STS diagnosed after 90 have distinct clinicopathological features, but comparable relapse-free survival, unless clinical practice guidelines recommendations are not applied. Standard management should be proposed to these patients if oncogeriatric status allows
Green Edge ice camp campaigns: understanding the processes controlling the under-ice Arctic phytoplankton spring bloom
International audienceThe Green Edge initiative was developed to investigate the processes controlling the primary productivity and the fate of organic matter produced during the Arctic phytoplankton spring bloom (PSB) and to determine its role in the ecosystem. Two field campaigns were conducted in 2015 and 2016 at an ice camp located on landfast sea ice southeast of Qikiqtarjuaq Island in Baffin Bay (67.4797N, 63.7895W). During both expeditions, a large suite of physical, chemical and biological variables was measured beneath a consolidated sea ice cover from the surface to the bottom at 360âm depth to better understand the factors driving the PSB. Key variables such as temperature, salinity, radiance, irradiance, nutrient concentrations, chlorophyll-a concentration, bacteria, phytoplankton and zooplankton abundance and taxonomy, carbon stocks and fluxes were routinely measured at the ice camp. Here, we present the results of a joint effort to tidy and standardize the collected data sets that will facilitate their reuse in other Arctic studies. The dataset is available at http://www.seanoe.org/data/00487/59892/ (Massicotte et al., 2019a)