184 research outputs found

    Rudolf Virchow

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    Emerging infectious diseases: a brief biographical heritage.

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    Emerging Infectious Diseases: 10 Years Running

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    An origami-based soft robotic actuator for upper gastrointestinal endoscopic applications

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    Soft pneumatic actuators have been explored for endoscopic applications, but challenges in fabricating complex geometry with desirable dimensions and compliance remain. The addition of an endoscopic camera or tool channel is generally not possible without significant change in the diameter of the actuator. Radial expansion and ballooning of actuator walls during bending is undesirable for endoscopic applications. The inclusion of strain limiting methods like, wound fibre, mesh, or multi-material molding have been explored, but the integration of these design approaches with endoscopic requirements drastically increases fabrication complexity, precluding reliable translation into functional endoscopes. For the first time in soft robotics, we present a multi-channel, single material elastomeric actuator with a fully corrugated design (inspired by origami); offering specific functionality for endoscopic applications. The features introduced in this design include i) fabrication of multi-channel monolithic structure of 8.5 mm diameter, ii) incorporation of the benefits of corrugated design in a single material (i.e., limited radial expansion and improved bending efficiency), iii) design scalability (length and diameter), and iv) incorporation of a central hollow channel for the inclusion of an endoscopic camera. Two variants of the actuator are fabricated which have different corrugated or origami length, i.e., 30 mm and 40 mm respectively). Each of the three actuator channels is evaluated under varying volumetric (0.5 mls-1 and 1.5 mls-1 feed rate) and pressurized control to achieve a similar bending profile with the maximum bending angle of 150°. With the intended use for single use upper gastrointestinal endoscopic application, it is desirable to have linear relationships between actuation and angular position in soft pneumatic actuators with high bending response at low pressures; this is where the origami actuator offers contribution. The soft pneumatic actuator has been demonstrated to achieve a maximum bending angle of 200° when integrated with manually driven endoscope. The simple 3-step fabrication technique produces a complex origami pattern in a soft robotic structure, which promotes low pressure bending through the opening of the corrugation while retaining a small diameter and a central lumen, required for successful endoscope integration

    Design of a Screw Extruder for Additive Manufacturing

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    Our aim is to show that the screw extrusion process is comparable to current FDM 3D printing processes by implementing an innovative design along with an advanced control algorithm. A thermistor array was used to detect the temperature profile along the barrel during the extrusion process for feedback. This provided information in regards to the location of the melting point during extrusion. The current prototype was able to achieve open loop extrusion out of a 0.2mm diameter nozzle with a maximum output flow rate of 7.14 mm/second and retain a controlled temperature profile using bang-bang control throughout the extrusion proces
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