The landscape is a trap:Duck decoys as multispecies atmospheres of deception and betrayal

Duck decoys are trapping devices designed to catch ducks. From the fourteenth century onwards, duck decoys emerged in riverine lowlands in northwestern Europe. Their operation is based on a rigorously maintained physical structure with a woodland that encloses a water body with protruding extensions called pipes, which end in nets and are surrounded by reed screens. Catching ducks in these places requires a complex interplay between different groups of ducks, a dog, and a human decoyman who together are enmeshed in what becomes a deeply deceptive landscape. This paper explores duck decoys in the Netherlands as relational, situated and co-designed multispecies atmospheres. Through ethnographic descriptions of field visits, interviews and by drawing on historical accounts, we trace how inter- and intraspecies relations and behaviours are interpreted in terms of deception, betrayal, trust and curiosity. The varying interpretations of behaviours and the more-than-human knowledges at play reflect the essentially elusive character of the duck decoy. Especially when facing the environmental challenges of the Anthropocene, duck decoys and the ambiguous relations that were until recently maintained in them, encourage us to consider the historical trapping and hunting landscapes as places made by multispecies atmospheres. Even though these atmospheres and the intimate collectives of human and more-than-human lives have become increasingly fragile, their afterlives resonate through the changing character of the riverine landscape and its various waterfowl, as well as practices of knowing and conserving biodiversity.</p

Mycobacterium bovis BCG Interferes with miR-3619-5p Control of Cathepsin S in the Process of Autophagy

Main survival mechanism of pathogenic mycobacteria is to escape inimical phagolysosomal environment inside the macrophages. Many efforts have been made to unravel the molecular mechanisms behind this process. However, little is known about the involvement of microRNAs (miRNAs) in the regulation of phagolysosomal biosynthesis and maturation. Based on a bottom up approach, we searched for miRNAs that were involved in phagolysosomal processing events in the course of mycobacterial infection of macrophages. After infecting THP-1 derived macrophages with viable and heat killed Mycobacterium bovis BCG (BCG), early time points were identified after co-localization studies of the phagosomal marker protein LAMP1 and BCG. Differences in LAMP1 localization on the phagosomes of both groups were observed at 30 min and 4 h. After in silico based pre-selection of miRNAs, expression analysis at the identified time points revealed down-regulation of three miRNAs: miR-3619-5p, miR-637, and miR-324-3p. Consequently, most likely targets were predicted that were supposed to be mutually regulated by these three studied miRNAs. The lysosomal cysteine protease Cathepsin S (CTSS) and Rab11 family-interacting protein 4 (RAB11FIP4) were up-regulated and were considered to be connected to lysosomal trafficking and autophagy. Interaction studies verified the regulation of CTSS by miR-3619-5p. Down-regulation of CTSS by ectopic miR-3619-5p as well as its specific knockdown by siRNA affected the process of autophagy in THP-1 derived macrophages

Sources of Intravascular ATP During Exercise in Humans: Critical Role for Skeletal Muscle Perfusion

Exercise hyperemia is regulated by several factors and one factor known to increase with exercise that evokes powerful vasomotor action is extracellular ATP. The origination of ATP detectable in plasma from exercising muscle of humans is, however, a matter of debate and ATP has been suggested to arise from sympathetic nerves, blood sources (e.g. erythrocytes), endothelial cells, and skeletal myocytes, among others. Therefore, we tested the hypothesis that acute augmentation of sympathetic nervous system activity (SNA) results in elevated plasma ATP draining skeletal muscle, and that SNA superimposition during exercise further increases ATP vs exercise alone. We show that increased SNA via −40mmHg lower body negative pressure (LBNP) at rest does not increase plasma ATP (51±8 vs 58±7 nmol/L with LBNP), nor does it increase [ATP] above levels observed during rhythmic handgrip exercise (79±11 exercise alone vs 71±8 nmol/L with LBNP). Secondly, we tested the hypothesis that active perfusion of skeletal muscle is essential to observe increased plasma ATP during exercise. We identify that complete obstruction of blood flow to contracting muscle abolishes exercise-mediated increases in plasma ATP (90±19 to 49±12 nmol/L), and further, that cessation of blood flow prior to exercise completely inhibits the typical rise in ATP (3 vs 61%; obstructed vs intact perfusion). The lack of ATP change during occlusion occurred in the face of continued muscle work and elevated SNA, indicating the rise of intravascular ATP is not resultant from these extravascular sources. Our collective observations indicate that the elevation in extracellular ATP observed in blood during exercise is unlikely to originate from sympathetic nerves or the contacting muscle itself, but rather is dependent on intact skeletal muscle perfusion. We conclude that an intravascular source for ATP is essential and points toward an important role for blood sources (e.g. red blood cells) in augmenting and maintaining elevated plasma ATP during exercise

Multispecies Communities

Prof. Dr. Jens Schröter, Dr. Pablo Abend und Prof. Dr. Benjamin Beil sind Herausgeber der Reihe. Die Herausgeber*innen der einzelnen Hefte sind renommierte Wissenschaftler*innen aus dem In- und Ausland."Multispecies Communities" sind nicht mehr alleine auf den Menschen fixiert und bringen andere Akteure ins Spiel. Damit ergeben sich neue Formen der Kommunikationen und Kollaborationen, der Verantwortlichkeiten und der Rücksichtnahmen (awareness), der Vergemeinschaftungen und der Teilhaben: Diese finden statt zwischen Menschen und Tieren, Pflanzen und Algorithmen, Artefakten und Biofakten, Maschinen und Medien; zwischen den Sphären von belebt und unbelebt, real und virtuell, unberührt und augmentiert. Der Umgang mit Technik ist längst kein menschliches Privileg mehr, wie die Ausdifferenzierungen von Human-Computer Interaction (HCI) in Animal-Computer Interaction (ACI) oder Plant-Computer Interaction (PCI) verdeutlichen. Diese Ausdifferenzierungen finden ihren Niederschlag ebenso in den verschiedenen Disziplinen der Wissenschaft und in der Kunst sowie in gesellschaftlichen, sozialen, ethischen und politischen Aushandlungen des gemeinsamen Miteinanders. In dieser Ausgabe sind für diesen Diskussionszusammenhang relevante programmatische Texte versammelt und erstmals für den deutschsprachigen Raum zugänglich gemacht."Multispecies communities" are no longer focused on humans alone and bring other actors into play. This results in new forms of communication and collaboration, of responsibilities and awareness, of communalisation and participation: These take place between humans and animals, plants and algorithms, artefacts and biofacts, machines and media; between the spheres of animate and inanimate, real and virtual, untouched and augmented. Dealing with technology is no longer a human privilege, as the differentiations from Human-Computer Interaction (HCI) into Animal-Computer Interaction (ACI) or Plant-Computer Interaction (PCI) exemplify. These differentiations are also reflected in the various disciplines of science and art as well as in societal, social, ethical and political negotiations of shared interaction. In this issue, relevant programmatic texts have been collected for this discussion context and made available for the first time for the German-speaking area

A Philosophy of “Doing” in the Digital

Playing in counterpoint with the general theoretical orientation of the book, this chapter does not focus its attention on the recording and archiving capabilities of the digital medium. Instead, it proposes an understanding of the digital medium that focuses on its disclosing various forms of “doing.” Gualeni’s chapter begins by offering an understanding of “doing in the digital” that methodologically separates “doing as acting” from “doing as making.” After setting its theoretical framework, the chapter discusses an “interactive thought experiment” designed by the author that is analyzed as a digital artifact leveraging both dimensions of “doing in the digital” for philosophical purposes. In extreme synthesis, one could say that this chapter is about several kinds of soups

Zur Bedeutung des Alters bei Beginn des chronischen Alkoholismus – Ein Überblick

Driessen M, Veltrup C. Zur Bedeutung des Alters bei Beginn des chronischen Alkoholismus – Ein Überblick. Psychiatrische Praxis. 1994;21(1):24-28.In dem vorliegenden Artikel wird ein kurzer Überblick über den gegenwärtigen Stand der Literatur zur Bedeutung des Alters bei Beginn des chronischen Alkoholismus gegeben. Empirische Studien der letzten 20 Jahre beschäftigen sich vorwiegend mit dem Krankheitsbeginn im Jugendalter und der Abgrenzung gegenüber Befunden bei Beginn im mittleren Erwachsenenalter. Nur wenige Arbeiten dagegen beschreiben spezifische Merkmale bei Entwicklung des Alkoholismus im Präsenium und Senium. Es wird auf biologische und psychosoziale Befunde sowie therapeutische Überlegungen eingegangen und ihre Bedeutung im Rahmen der Alkoholismusforschung und praktischen Betreuung Abhängiger diskutiert

Farms, Landscapes, Food and Relationships

This chapter offers an overview of understandings of the relations between farmers or farm workers and the animals on their farms. First of all, the character of these relations is found to depend on the type of farm: the species of animals used, the type of animal products that are produced, the scale of production and the system and ideal of operation (e.g. free range, cage based, etc.). Within the resulting categories of farms—or animal production operations—there are different ways of characterizing and appreciating human-animal relations. This results in a mixed discourse that may use registers of care, alienation, exploitation, tradition, bond, attunement and technological mediation. This chapter discusses implications of these aspects for understanding (changing) human-animal relations on farms, and based on that, the potential for regulating human-animal relations and the ethical experiences these may generate. Looking beyond the farm, the chapter also reflects on the figure of the consumer and its role in imagining human-animal relations on farms. The aim is to give an active role to the consumer especially at a time when the need to seriously consider the role of human beings with respect to the environment and animals—but also in the inequalities that occur between human beings themselves, particularly evident in the food production chains. Arguably scientific research into animal welfare, proposals for technical innovations and the production of regulations undoubtedly contribute to improving the living conditions of animals; but at the same time also reduce the collective moral tension to increase the quality of life of animals—and the humans involved in caring for them. For this, we argue society as a whole to be responsible

Erweiterte Entzugsbehandlung für alkoholabhängige Patienten in einer psychiatrischen Klinik

Veltrup C, Driessen M. Erweiterte Entzugsbehandlung für alkoholabhängige Patienten in einer psychiatrischen Klinik. Sucht. 1993;39(3):168-172

Interpreting the YouTube zoo : Ethical potential of captive encounters

YouTube hosts a vast number of videos featuring zoo animals and humans actively reacting to each other. These videos can be seen as a popular genre of online entertainment, but also as a significant visual artefact of our relations with animals in the age of humans. In this chapter we focus on two viral videos featuring captive orangutans interacting with zoo visitors. The interpretations of ape-human interactions arising from the extensive number of comments posted to the videos are ambivalent in how they see the animals and their assumed capabilities. We argue that the YouTube Zoo could figure as a snapshot of human-animal relations in late modern times: mediating artificial conditions of animals suspended between the wild and the domestic, while offering a screened account of a deeply surprising interaction. The chapter shows the potential of close interactions between humans and animals to destabilise or reinforce the neat divisions between the human and the animal. It also shows the ethical potential of these interactions to either reinforce or question common practices of dealing with wild animals.</p