Surface Modifications of Orthodontic Bone Screws - A Novel Approach

Anchorage control plays a key role in the correction of malocclusion. With the advent of orthodontic bone screws, attaining absolute anchorage control has become hassle free. They have the advantages of low cost, simple surgical placement, and ease of removal; therefore, they are convenient in the treatment of various malocclusions. Although the clinical stability of bone screws is exceptionally high, stability of the bone screws is compromised by factors such as microbial contamination and morphological defects. To overcome this, surface modifications are introduced to enhance the stability of the bone screws

Analytical study of modified Manashiladi Lepa into Ointment

Lepa Kalpana is one amongst the external application used in Ayurveda. Manashiladi Lepa is a formulation explained in ‘Rasa Tantra Sara Va Siddha Prayoga Sangraha’ for the prevention of scar in the skin surface. The formulation contains Ghrita and Madhu which is to be mixed with the powder of the herbs told in the formulation. In the present scenario, the Lepa Kalpana is not liked by the patients themselves as it leaves behind residual marks on the skin surface and stains the cloth if it comes in contact with it. Hence a modified Lepa in the form of ointment which contains reduced amount of oiliness and good packing is accepted by all. Literary review done through various sources like books, journals and internet revealed that, no modification studies have been carried out on this formulation yet. The Lepa is modified into an ointment for its easy acceptability and usage. The formulation is tested for its analytical values and discussed in the article

Role of Human Resource Management in Sustainable Development

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Review of Fuel Management practices at various stages of nuclear fuel cycle in PHWRs in view of Environmental effects

Nuclear Power is emerging as a promising source of environmentally benign energy source alternate from both pollution free environment as well as solution to global warming because of minimal carbon footprint. However, release of radiation and radioactive contamination during fuel cycle operations comprising the optimum fuel utilization in Nuclear Reactors, still remains a challenge to contain the sources of radiation and contamination away from public domain. This review article envisages qualitatively the environmental effects w.r.t. radiation during flow of Natural Uranium fuel used in Indian Pressurized Heavy Water Reactors (IPHWRs) at various stages of mining, fabrication, transportation, operation in nuclear reactors, and storage after operation. The review has been completed by detailed compilation and study of the involved activities in the nuclear fuel cycle. Advanced modelling and computational analysis techniques are being employed at various stages, which form the basis for various administrative and technical measures to ensure minimal radiation exposure. It is concluded that organizations engaged in these activities are committed to minimum environmental impact and follow a safety culture in their system and among workers to ensure best administrative control in handling of radiation and radiation sources to limit exposure to public domain. In view of the limitations of LNT (Linear No Threshold) principle and the presence of radiation due to natural sources in the environment, it is desirable to revisit the provisions of ALARA principle (As low as reasonably achievable) as presently being followed in carrying out any activity related to radiation and radiation sources

E-LEARNING: A NEW WAY OF LIBRARY AND INFORMATION SCIENCE EDUCATION THROUGH DISTANCE MODE*

Abstract This study explored that the e-learning mechanism is required to provide for quality of Library and Information Science education at university level through the distance learning. This paper is divided into three sections. The first section deals with the LIS education in distance mode. Second section examines the developments of E-learning and LIS education in India. Third Section spells out the universities are forced to face the following major challenges to adopt e-learning mechanisms, which are to design LIS programmes to fit into the e-learning environment, to provide quality education, the teachers aswellas students are to be trained the information technology advancement, to enhance LIS education e-learning consortium, collaboration, quality assurance with accreditation and cost effective were discussed in details to strengthening the LIS education

ANTIMICROBIAL AND PHYTOCHEMICAL EVALUATION OF CISSUS QUADRANGULARIS L.

The present investigation involves antimicrobial and phytochemical evaluation of Cissus quadrangularis L. The antibacterial activity of Cissus quadrangularis was performed using disk diffusion method. The Results of study proved prompt efficacy of herbal extract against S. aureus and E. coli. The concentration dependent antibacterial activity of extract was observed against both organisms. Study also involves phytochemical investigation of herbal extract using HPTLC, IR and UV-Visible spectrophotometer. The result of study indicated that the methanolic extract possessed most potent antibacterial activity as compared to other extract. The antibacterial activity increases with the concentration and results indicated that the diameters of zone inhibition of the extract were comparable with the standard drug. The antimicrobial potential of plant extract may be attributed to the presence of specific phytoconstituents

HEAT TRANSFER ANALYSIS OF RECUPERATIVE AIR PREHEATER

Abstract: Steam generators are very complex class of pressure vessels. It contains many accessories for the generation of required steam quality. The prime motto of industrial steam generator is to generate steam at medium pressure (MP), low pressure (LP) steam at required pressure temperature and quantity for the process industry like sugar, paper, jute and chemical industries. LP and MP steam after expansion in the turbine from super saturation is utilized by process industry. In the present work Air Preheater, one of the accessories of the steam generator is analysed. Air preheaters make a considerable contribution to the improved overall efficiency of fossil-fuel-fired power plants. In this study, a theoretical design of Recuperative Primary Air preheater with In-line tube arrangement and a combination of fluid dynamics analysis with theoretical value. The model enables heat transfer of the flue-gas flow through the air preheater as well as the tubular heat transfer and the resulting temperature distribution in the matrix of the preheater. The present work is carried in Mysore Paper Mills (MPM) Bhadravathi, CFD (Computational Fluid Dynamics) analysis of recuperative air preheater is carried out using ANSYS CFX-12.1.The analysis of flue gas flow phenomenon and air flow phenomenon are discussed using Laminar model, k-ε model, k-ω model and SST model. The parameters like temperature distribution, heat flux, pressure drop, velocity, are also discussed. An increase of 2.7% in boiler efficiency was found out with incorporation of this design, their by an increase in the air inlet temperature of about 60℃ is been observed

Chromosomal-level assembly of the Asian Seabass genome using long sequence reads and multi-layered scaffolding

We report here the ~670 Mb genome assembly of the Asian seabass (Lates calcarifer), a tropical marine teleost. We used long-read sequencing augmented by transcriptomics, optical and genetic mapping along with shared synteny from closely related fish species to derive a chromosome-level assembly with a contig N50 size over 1 Mb and scaffold N50 size over 25 Mb that span ~90% of the genome. The population structure of L. calcarifer species complex was analyzed by re-sequencing 61 individuals representing various regions across the species' native range. SNP analyses identified high levels of genetic diversity and confirmed earlier indications of a population stratification comprising three clades with signs of admixture apparent in the South-East Asian population. The quality of the Asian seabass genome assembly far exceeds that of any other fish species, and will serve as a new standard for fish genomics

Meiosis-Specific Loading of the Centromere-Specific Histone CENH3 in Arabidopsis thaliana

Centromere behavior is specialized in meiosis I, so that sister chromatids of homologous chromosomes are pulled toward the same side of the spindle (through kinetochore mono-orientation) and chromosome number is reduced. Factors required for mono-orientation have been identified in yeast. However, comparatively little is known about how meiotic centromere behavior is specialized in animals and plants that typically have large tandem repeat centromeres. Kinetochores are nucleated by the centromere-specific histone CENH3. Unlike conventional histone H3s, CENH3 is rapidly evolving, particularly in its N-terminal tail domain. Here we describe chimeric variants of CENH3 with alterations in the N-terminal tail that are specifically defective in meiosis. Arabidopsis thaliana cenh3 mutants expressing a GFP-tagged chimeric protein containing the H3 N-terminal tail and the CENH3 C-terminus (termed GFP-tailswap) are sterile because of random meiotic chromosome segregation. These defects result from the specific depletion of GFP-tailswap protein from meiotic kinetochores, which contrasts with its normal localization in mitotic cells. Loss of the GFP-tailswap CENH3 variant in meiosis affects recruitment of the essential kinetochore protein MIS12. Our findings suggest that CENH3 loading dynamics might be regulated differently in mitosis and meiosis. As further support for our hypothesis, we show that GFP-tailswap protein is recruited back to centromeres in a subset of pollen grains in GFP-tailswap once they resume haploid mitosis. Meiotic recruitment of the GFP-tailswap CENH3 variant is not restored by removal of the meiosis-specific cohesin subunit REC8. Our results reveal the existence of a specialized loading pathway for CENH3 during meiosis that is likely to involve the hypervariable N-terminal tail. Meiosis-specific CENH3 dynamics may play a role in modulating meiotic centromere behavior