276 research outputs found

    15 Jahre alt 1992 - heute über dreissig. Über eine 15jährige Entwicklung der schulischen und beruflichen Übergänge nach der obligatorischen Schulzeit

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    En 1992, la moitié des jeunes tessinois (N=1471) qui venaient de terminer leur scolarité obligatoire ont participé à une recherche longitudinale qui s\u27est terminée quinze ans plus tard, en 2007. La recherche présentée ici a suivi les parcours scolaires et professionnels de ces jeunes adultes afin de mieux saisir les logiques et les stratégies adoptées dans leurs choix de parcours de formation et au moment du passage en emploi. Le dispositif adopté a permis de réaliser un suivi soutenu quant au relevé des données et aux thèmes analysés (formation, travail, valeurs, aspects culturels, dimensions sociodémographiques, degré de satisfaction, etc.). Cette recherche a pu réunir beaucoup d\u27information et a déjà fait l\u27objet de nombreuses publications. Dans la présente contribution, il a été été démontré que, à l\u27âge de trente ans, les jeunes adultes sont assez satisfaits de leur vie, qu\u27ils ont acquis une bonne formation et par la suite une place de travail stable. Ils considèrent les amis et la famille comme très importants, tout comme les loisirs et le travail. Ils disent avoir confiance dans les enseignants, les scientifiques et la police, mais moins dans l\u27église, les partis politiques et les hommes politiques eux-mêmes. Ce portrait d\u27ensemble nous renseigne sur les parcours par moments ardus et parsemés d\u27interruptions, de changements de formation, de difficultés à trouver un premier emploi stable, de compromis salariaux et de quelques regrets, le plus souvent en lien direct avec les choix scolaires et professionnels effectués. (DIPF/Orig.)15 Jahre lang standen 1471 Schulabgänger/innen des Jahrganges 1992 (50% mit Sekundarabschluss) im Fokus einer Längsschnittstudie, die 2007 abgeschlossen wurde. Ein wesentliches Ziel bestand darin, Logiken und Strategien betreffend der Berufswahl und des Berufseinstiegs zu erkennen und zu dokumentieren. Zusätzlich wurden individuelle Entwicklungen im schulischen wie auch im beruflichen Kontext nachgezeichnet und verfolgt. Die Untersuchungsanlage ermöglichte eine intensive und nachhaltige Aufarbeitung der Erhebungsdaten wie auch der breit gefächerten Untersuchungsthemen (Ausbildung, Arbeit, Werte, kulturelle Aspekte, soziografische Dimensionen, Zufriedenheit etc.). Die Längsschnittstudie brachte umfassende Daten und Informationen zu Tage, welche in diversen Publikationen bereits dargelegt werden konnten. Deutlich wurde, dass die heute über dreißigjährigen jungen Erwachsenen mehrheitlich mit ihrem Leben zufrieden sind, unterstützt durch eine gute Ausbildung und integriert in der Arbeitswelt. Familiäre und freundschaftliche Beziehungen sind zentrale Werte, neben Freizeitbeschäftigungen und der Arbeit; sie geben an, Vertrauen in die Arbeit von Lehrerinnen und Lehrern, von Wissenschaftler/ innen und der Polizei zu haben; weniger stark in die Arbeit der Kirchen, politischer Parteien sowie von Politikerinnen und Politikern. Die Daten ergeben ein Bild einer Generation, deren individuelle Biografien nicht immer linear verlaufen und durch Friktionen gekennzeichnet sind, ausgelöst durch Wechsel in der Ausbildung, durch die Schwierigkeit eine erste Stelle zu finden, durch Gehaltseinbußen oder durch falsche bzw. problematische Berufswahlentscheide. (DIPF/Orig.

    Análise Numérica da Interação Fluido-Estrutura em Trocadores de Calor do Tipo PSHE

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    TCC (graduação) - Universidade Federal de Santa Catarina. Campus Joinville. Engenharia Aeroespacial.Com o consumo intenso de combustíveis fósseis no mundo, indústrias petroquímicas e de apoio investem cada vez mais em pesquisa e desenvolvimento de produtos e processos com o objetivo de aumentar a produção e facilitar a manutenção de aparelhos já existentes. Junto a isso, a necessidade do controle de temperatura nos diversos processos que englobam a manipulação dos insumos torna os trocadores de calor peças fundamentais na indústria. Em especial, trocadores de calor do tipo casco e placas, ou PSHE, são preferíveis em diversos aspectos, dentre eles, o tamanho compacto, as condições de operação elevadas e a eficiência térmica elevada. O presente trabalho desenvolveu resoluções numéricas para os problemas termo-fluidodinâmico e estrutural de forma acoplada, a fim de determinar campos de tensão e deslocamento, definir a hierarquia de influência das cargas térmica e mecânica e analisar seus respectivos comportamentos. Os resultados obtidos foram de que a maior contribuição nas tensões é a carga mecânica, com diferença de ordem de grandeza nas tensões de aproximadamente 100 vezes. Já a carga térmica se mostrou influenciada grandemente pela diferença de temperaturas dos domínios sólido e fluido, tendo um aumento de aproximadamente 0,40 MPa por consequência de um aumento de 25ºC na diferença de temperaturas entre os domínios

    Educação familiar em linguagem infantil: contribuições do grupo focal

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    The Focus Group has been used in the area of Humanities as a method to identify perceptions of different social groups, in the most diverse themes. The objective of this work is to present the contributions from the focus group used with mothers of children with global development delays in a research that aimed to develop and to tailor fascicles of family counseling to language. The focus group was composed of four mothers, the researcher, who assumed the role of moderator, and an observer, mainly responsible for registration of non-verbal behaviors of the participants. In the first reunion, guidance was given on the purpose of the meetings; the commitment to the issue of opinions regarding the features of the format and content of the volumes; and as to the functions of the observer and moderator. Eight face-to-face meetings were held fortnightly over four months. Verbal reports of the constituents of the Group were registered through audio recordings, transcribed and arranged for further analysis. The focus group showed appropriate procedure to involve parents in a reflective exercise concerning the development of communication and to define the content and format of guidelines written for the target population. The results indicated that the preparation of installments, in partnership with families, made it possible for parents to expand participation in the language development of their children. In addition, it was evident the interaction between the participants, as a focal group, set up in the triggering factor for identifying common aspects in the inter-subjective plan.Na área das Ciências Humanas, o Grupo Focal vem sendo utilizado como método para identificar percepções de diferentes grupos sociais, nas mais diversas temáticas. O objetivo do presente trabalho é apresentar as contribuições do grupo focal utilizado com mães de crianças com atrasos globais do desenvolvimento, em uma pesquisa que visou elaborar e adequar fascículos de orientação familiar em linguagem. O grupo focal foi constituído por quatro mães, a pesquisadora, que assumiu o papel de moderadora e uma observadora, responsável, principalmente, por fazer o registro de comportamentos não verbais das participantes. No primeiro encontro foram dadas orientações quanto: ao objetivo das reuniões; o compromisso com a emissão de opiniões a respeito das características de formato e conteúdo dos fascículos; e quanto às funções da observadora e da moderadora. Foram realizadas oito reuniões presenciais, quinzenalmente, ao longo de quatro meses. Os relatos verbais das constituintes do grupo foram registrados por meio de gravações de áudio, transcritos e organizados para posterior análise. O grupo focal se mostrou como procedimento adequado para envolver os pais num exercício reflexivo a respeito do desenvolvimento da comunicação e para definir os conteúdos e o formato de orientações escritas para a população-alvo. Os resultados indicaram que a elaboração dos fascículos, em parceria com as famílias, oportunizou aos pais ampliar a participação no desenvolvimento da linguagem de seus filhos. Além disso, restou evidenciado que a interação entre os participantes, nos moldes de um grupo focal, configurou-se em fator desencadeador para a identificação de aspectos comuns no plano intersubjetivo

    The Structure of the Emotional Processing Scale (EPS-25): An Exploratory Structural Equation Modeling Analysis Using Medical and Community Samples

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    The Emotional Processing Scale (EPS) assesses emotional processing in terms of suppression, signs of unprocessed emotion, controllability of emotions, avoidance of emotional triggers, and impoverished emotional experience. Previous confirmatory factor analyses (CFA) yielded insufficient fit and questioned the EPS factors' discriminant validity. The present study aimed to test unidimensional, five-factor, and bifactor models using exploratory structural equation modeling (ESEM) and CFA. We administered the scale to 350 Italian participants in good health and 346 gastrointestinal patients referred for endoscopy because of mild-to-severe gastrointestinal symptoms. ESEM models outperformed corresponding CFA models. The bifactor ESEM model was a good fit in single group analyses and achieved metric and scalar invariance in multigroup analyses. The inspection of latent mean differences revealed a consistent trend for patients to avoid emotional triggers and have less general emotional processing difficulties. The study clarified the EPS factor structure and supported its use to assess the emotional processing of medical patients and community participants

    What do we learn from the shape of the dynamical susceptibility of glass-formers?

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    We compute analytically and numerically the four-point correlation function that characterizes non-trivial cooperative dynamics in glassy systems within several models of glasses: elasto-plastic deformations, mode-coupling theory (MCT), collectively rearranging regions (CRR), diffusing defects and kinetically constrained models (KCM). Some features of the four-point susceptibility chi_4(t) are expected to be universal. at short times we expect an elastic regime characterized by a t or sqrt{t} growth. We find both in the beta, and the early alpha regime that chi_4 sim t^mu, where mu is directly related to the mechanism responsible for relaxation. This regime ends when a maximum of chi_4 is reached at a time t=t^* of the order of the relaxation time of the system. This maximum is followed by a fast decay to zero at large times. The height of the maximum also follows a power-law, chi_4(t^*) sim t^{*lambda}. The value of the exponents mu and lambda allows one to distinguish between different mechanisms. For example, freely diffusing defects in d=3 lead to mu=2 and lambda=1, whereas the CRR scenario rather predicts either mu=1 or a logarithmic behaviour depending on the nature of the nucleation events, and a logarithmic behaviour of chi_4(t^*). MCT leads to mu=b and lambda =1/gamma, where b and gamma are the standard MCT exponents. We compare our theoretical results with numerical simulations on a Lennard-Jones and a soft-sphere system. Within the limited time-scales accessible to numerical simulations, we find that the exponent mu is rather small, mu < 1, with a value in reasonable agreement with the MCT predictions.Comment: 26 pages, 6 figure

    Prospective Evaluation of MGMT-Promoter Methylation Status and Correlations with Outcomes to Temozolomide-Based Chemotherapy in Well-Differentiated Neuroendocrine Tumors

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    Temozolomide (TEM) as a single agent or in combination with capecitabine (CAPTEM) is active in well-differentiated advanced neuroendocrine tumors (NETs) of gastro-entero-pancreatic and thoracic origin. The predictive role of MGMT-promoter methylation in this setting is controversial. We sought to prospectively evaluate the MGMT-promoter methylation status ability to predict outcomes to TEM-based chemotherapy in patients with NET. A single-center, prospective, observational study has been conducted at the ENETS Center-of-Excellence Outpatient Clinic of the IRCCS Policlinico Sant’Orsola-Malpighi in Bologna, Italy. Patients with advanced, gastro-entero-pancreatic or lung well-differentiated NETs candidate to TEM-based chemotherapy and with available tumor samples for MGMT-promoter methylation assessment were included. The MGMT-promoter methylation status was analyzed by using pyrosequencing. The primary endpoint was progression-free survival (PFS) by the MGMT-promoter methylation status. Secondary endpoints included overall survival (OS), objective response rate (ORR), disease control rate (DCR), and safety. Survival outcomes were compared by restricted mean survival time (RMST) difference. Of 26 screened patients, 22 were finally enrolled in the study. The most frequent NET primary sites were the pancreas (64%) and the lung (23%). MGMT promoter was methylated in five tumors (23%). At a median follow-up time of 47.2 months (95%CI 29.3–89.7), the median PFS was 32.8 months (95%CI 17.2–NA), while the median OS was not reached. Patients in the methylated MGMT group, when compared to those in the unmethylated MGMT group, had longer PFS (median not reached [95%CI NA–NA] vs. 30.2 months [95%CI 15.2–NA], respectively; RMST p = 0.005) and OS (median not reached [95%CI NA–NA] vs. not reached [40.1–NA], respectively; RMST p = 0.019). After adjusting for confounding factors, the MGMT-promoter methylation status was independently associated to the PFS. Numerically higher ORR (60% vs. 24%; p = 0.274) and DCR (100% vs. 88%; p = 1.00) were observed in the methylated vs. unmethylated MGMT group. TEM-based chemotherapy was well-tolerated (adverse events grade ≥3 &lt; 10%). In this prospective study, MGMT-promoter methylation predicted better outcomes to TEM-based chemotherapy in patients with NET

    Data Collection and Reporting Guidelines for European electro-mobility projects

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    Analysis of the data collected from electro-mobility projects has shown that only in very limited cases, the data reported were of enough quality and/or comprehensive enough to allow a meaningful and complete analysis. Various types of data are sometimes missing, making it almost impossible to analyse them correctly. The objective of this report is to provide guidance to publicly funded European Electro-mobility Projects on what and how to monitor and report. Detailed description of the necessary monitored elements and those which are considered as optional due to the complexity or expense involved in collecting them, is included, as well some ideas on quality control and on data collection. An extensive stakeholder consultation has taken place before the release of this report.JRC.F.6-Energy Technology Policy Outloo

    Consultoria colaborativa no ensino superior, tendo por foco um estudante com Transtorno do Espectro Autista

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    A área da Educação Especial tem natureza transversal, extrapolando, portanto, o estudante como único alvo. Suas ações devem incluir o docente como destinatário de formação específica, que deve ser continuada, flexível e se concretizar na prática diária da sala de aula. O presente relato de caso objetiva descrever os procedimentos de uma consultoria colaborativa realizada por um profissional especialista, em parceria com gestores universitários, com docentes de um curso superior de Matemática, tendo por foco um estudante com Transtorno do Espectro Autista. Foram aplicados ajustes nas estratégias de avaliação, incluindo: adequação linguística das questões e aceite de respostas orais, com apoio de solução no papel ou na lousa. O processo avaliativo foi registrado por meio de anotações, fotografias e gravações de áudio e vídeo. Ao final, as docentes relataram que foi determinante o uso das estratégias para avaliar a aprendizagem do estudante, considerando o insucesso em oportunidades anteriores

    Anaerobic leaching of covellite by Thiobacillus ferrooxidans

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    Thiobacillus ferrooxidans was able to grow under anaerobic conditions on copper sulphide with ferric ion as the electron acceptor. The dissolution of covellite under these conditions (68% after 35 days) was higher than values observed aerobically in cultures with similar media composition and almost as high as under aerobic conditions without iron. From these results we propose a mechanism for anaerobic bioleaching of covellite in the presence of ferric iron and speculate that it may occur in leach dumps where the oxygen concentration is, as reported elsewhere, very low.Centro de Investigación y Desarrollo en Fermentaciones Industriale

    Indirect bioleaching of covellite by Thiobacillus thiooxidans with an oxidant agent

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    High copper extraction by the action of Thiobacillus thiooxidans (T.t.) on covellite in presence of iron(III) is explained by indirect mechanism, in which T.t. only oxidizes the layer of sulphur that covers the sulphide surface allowing sulphide oxidation by iron(III). In cultures on elemental sulphur with iron(III) T.t. is not able to use iron(III) as an acceptor of electrons in sulphur oxidation; iron(III) only oxidizes those intermediates which were generated in the aerobic oxidation of sulphur.Centro de Investigación y Desarrollo en Fermentaciones Industriale
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