34 research outputs found
Comparing leadership internationally: challenges and reflections
This paper is a co-written paper by five MA Education students at the University of Northampton and James Underwood, Principal Lecturer at the University of Northampton and a PhD student at the University of Cambridge. We are all currently engaged in research that involves comparing aspects of education in the UK with another nation. The research that we are each personally undertaking addresses a range of topics. These all relate to an aspect of education leadership ranging from student leadership to school and university management. There is one common underlying research question which underpins all the studies which is: in what ways has comparison between nations been a valid approach to understanding education and leadership? This question is addressed successively via our individual stories in this paper. This paper is linked to a paper presented in May 2015 at the University of Cambridge entitled: “Breaking boundaries as writers, researchers and me-searchers, the challenges and rewards of completing an MA as a community of practice.” In which we discussed in depth our experience as a research community. This paper has therefore also been informed by a distinct perspective on the nature of Masters’ level study
Cohort profile: Ho Chi Minh City Youth Cohort—changes in diet, physical activity, sedentary behaviour and relationship with overweight/obesity in adolescents
Breaking boundaries as writers and researchers, the challenges and rewards of completing an MA as a community of practice
This paper is a co-written paper by five postgraduate students at the University of Northampton and one lecturer who is also a PhD student at the University of Cambridge. In it we discuss how as a group of students we broke down barriers between ourselves as individuals to create a community of practice rather than a class. All of us are currently engaged in research that involves comparing aspects of education in the UK with another nation. In the case of five of the writers this is with the nation in which we grew up. We deliberately chose areas of study that were intertwined and negotiated our thesis titles with each other to ensure that the research would be mutually supportive. It has been this method of collective writing and of reflective data collection that has been particularly innovative and that we will be presenting in this paper. Although the individual dissertations will be submitted separately, this approach has enabled us to build emotional resilience, and to generate work of a greater depth than would otherwise have been possible. In this way this paper fits with the conference theme ‘many paths, same goal’. The paper opens with an extended metaphor linking research to cricket and specifically to the great West Indian cricket captain Clive Lloyd. Metaphors can open up new ways of thinking as this one did for us
Factors Affecting Consumers’ Impulsive Purchasing Behavior in Circle K Convenience Stores in Hanoi, Vietnam
Impulsive purchasing behavior has been observed as one of the important studies conducted by marketers and researchers, as impulse buying has become a prevalent phenomenon in every retail format. The study was conducted to assess factors affecting consumers’ impulsive purchasing behavior in Circle K convenience stores in Hanoi, Vietnam. After reviewing a group of previous studies, the authors indicated 05 factors that affected consumers' impulsive purchasing behavior including impulsiveness, instant gratification, visual appeal, promotions and money availability. The study had selected 05 experts in the field of economics to conduct the expert interview. Moreover, the research team had also handed out the questionnaire and received 310 observations. Specifically, Impulsiveness had the strongest influence on the impulsive purchasing behavior of Circle K’s consumers in Hanoi. Keywords: factors, Impulsive purchasing behavior, Circle K convenience stores DOI: 10.7176/JESD/14-8-03 Publication date: April 30th 2023
Chemical Components of Essential Oils From the Leaves of Seven Species Belonging to Rutaceae Family from Binh Chau-Phuoc Buu Nature Reserve, Vietnam
Several plant species of the Rutaceae family are medicinal plants, oil bearing and food crops. To provide more information for utilization of some species of this family in Binh Chau-Phuoc Buu Nature Reserve, we extracted essential oils from the leaves of seven species of the Rutaceae family: Acronychia pedunculata (L.) Miq., Atalantia citroides Pierre ex Guillaumin, Clausena excavata Burm.f., Glycosmis pentaphylla (Retz.) DC., Luvunga scandens (Roxb.) Buch.-Ham. ex Wight & Arn, Melicope pteleifolia (Champ. ex Benth.) T.G. Hartley, and Micromelum sp., via hydrodistillation, and identified their components using GC/MS analysis. A total of 60 compounds were identified from essential oils of seven species. The main components of the essential oils isolated from five species, including A. pedunculata, C. excavata, M. pteleifolia, G. pentaphylla, and Micromelum sp., were caryophyllene (57.63% and 55.41% in A. pedunculata and C. excavata, respectively), 1,9-decadiyne (32.59%, M. pteleifolia), β-ocimene (23.10%, G. pentaphylla), and 3-carene (58.03%, Micromelum sp.). Additionally, this study revealed the chemical composition of essential oils of L. scandens and A. citroides for the first time. The main constituent of A. citroides was 7-oxabicyclo[4.1.0] heptane, 3-oxiranyl- (53.91%) and that of L. scandens was caryophyllene (34.66%). These findings provide the basis for further application of these species in medicine
Rifampicin resistant 'Mycobacterium tuberculosis' in Vietnam, 2020–2022
Objective: We conducted a descriptive analysis of multi-drug resistant tuberculosis (MDR-TB) in Vietnam’s two largest cities, Hanoi and Ho Chi Minh city.
Methods: All patients with rifampicin resistant tuberculosis were recruited from Hanoi and surrounding provinces between 2020 and 2022. Additional patients were recruited from Ho Chi Minh city over the same time period. Demographic data were recorded from all patients, and samples collected, cultured, whole genome sequenced and analysed for drug resistance mutations. Genomic susceptibility predictions were made on the basis of the World Health Organization’s catalogue of mutations in Mycobacterium tuberculosis associated with drug resistance, version 2. Comparisons were made against phenotypic drug susceptibility test results where these were available. Multivariable logistic regression was used to assess risk factors for previous episodes of tuberculosis.
Results: 233/265 sequenced isolates were of sufficient quality for analysis, 146 (63 %) from Ho Chi Minh City and 87 (37 %) from Hanoi. 198 (85 %) were lineage 2, 20 (9 %) were lineage 4, and 15 (6 %) were lineage 1. 17/211 (8 %) for whom HIV status was known were infected, and 109/214 (51 %) patients had had a previous episode of tuberculosis. The main risk factor for a previous episode was HIV infection (odds ratio 5.1 (95 % confidence interval 1.3–20.0); p = 0.021). Sensitivity for predicting first-line drug resistance from whole genome sequencing data was over 90 %, with the exception of pyrazinamide (85 %). For moxifloxacin and amikacin it was 50 % or less. Among rifampicin-resistant isolates, prevalence of resistance to each non-first-line drug was < 20 %.
Conclusions: Drug resistance among most MDR-TB strains in Vietnam’s two largest cities is confined largely to first-line drugs. Living with HIV is the main risk factor among patients with MDR-TB for having had a previous episode of tuberculosis
Can a Short Food Supply Chain Create Sustainable Benefits for Small Farmers in Developing Countries? An Exploratory Study of Vietnam
A number of studies have indicated that short food supply chains could create economic, social, and environmental benefits, but most of those chains were implemented in developed countries. This research aims to find out the characteristics of short food supply chains and their benefits to small farmers in Vietnam, which is a developing country, based on the survey results from 338 small farmers in the third quarter of 2020, with the support of Stata 14 software. The results showed that the short food supply chains in the survey sample in Vietnam were characterized by two main actors: small farmers and distributors. Farmers could sell products flexibly at the local market. There was some initial evidence to prove that these chains helped to stabilize the input, output price, and revenue; formulated sustainable income; and increased the satisfaction and confidence of farmers. They eliminated gender discrimination in rural areas and improved livelihood for ethnic minorities. These chains also enhanced the mindset on green, organic, and clean production of farmers, which in turn created environmental benefits. COVID-19 has posed a negative impact on the income of farmers and made them change their production and sales method. Therefore, the research could suggest some policies to sustainably develop the short food supply chains in Vietnam in the future
The influence of human genetic variation on early transcriptional responses and protective immunity following immunization with Rotarix vaccine in infants in Ho Chi Minh City in Vietnam : a study protocol for an open single-arm interventional trial [awaiting peer review]
Background: Rotavirus (RoV) remains the leading cause of acute gastroenteritis in infants and children aged under five years in both high- and low-middle-income countries (LMICs). In LMICs, RoV infections are associated with substantial mortality. Two RoV vaccines (Rotarix and Rotateq) are widely available for use in infants, both of which have been shown to be highly efficacious in Europe and North America. However, for unknown reasons, these RoV vaccines have markedly lower efficacy in LMICs. We hypothesize that poor RoV vaccine efficacy across in certain regions may be associated with genetic heritability or gene expression in the human host.
Methods/design: We designed an open-label single-arm interventional trial with the Rotarix RoV vaccine to identify genetic and transcriptomic markers associated with generating a protective immune response against RoV. Overall, 1,000 infants will be recruited prior to Expanded Program on Immunization (EPI) vaccinations at two months of age and vaccinated with oral Rotarix vaccine at two and three months, after which the infants will be followed-up for diarrheal disease until 18 months of age. Blood sampling for genetics, transcriptomics, and immunological analysis will be conducted before each Rotarix vaccination, 2-3 days post-vaccination, and at each follow-up visit (i.e. 6, 12 and 18 months of age). Stool samples will be collected during each diarrheal episode to identify RoV infection. The primary outcome will be Rotarix vaccine failure events (i.e. symptomatic RoV infection despite vaccination), secondary outcomes will be antibody responses and genotypic characterization of the infection virus in Rotarix failure events.
Discussion: This study will be the largest and best powered study of its kind to be conducted to date in infants, and will be critical for our understanding of RoV immunity, human genetics in the Vietnam population, and mechanisms determining RoV vaccine-mediated protection.
Registration: ClinicalTrials.gov, ID: NCT03587389. Registered on 16 July 2018
Safety and efficacy of fluoxetine on functional outcome after acute stroke (AFFINITY): a randomised, double-blind, placebo-controlled trial
Background
Trials of fluoxetine for recovery after stroke report conflicting results. The Assessment oF FluoxetINe In sTroke recoverY (AFFINITY) trial aimed to show if daily oral fluoxetine for 6 months after stroke improves functional outcome in an ethnically diverse population.
Methods
AFFINITY was a randomised, parallel-group, double-blind, placebo-controlled trial done in 43 hospital stroke units in Australia (n=29), New Zealand (four), and Vietnam (ten). Eligible patients were adults (aged ≥18 years) with a clinical diagnosis of acute stroke in the previous 2–15 days, brain imaging consistent with ischaemic or haemorrhagic stroke, and a persisting neurological deficit that produced a modified Rankin Scale (mRS) score of 1 or more. Patients were randomly assigned 1:1 via a web-based system using a minimisation algorithm to once daily, oral fluoxetine 20 mg capsules or matching placebo for 6 months. Patients, carers, investigators, and outcome assessors were masked to the treatment allocation. The primary outcome was functional status, measured by the mRS, at 6 months. The primary analysis was an ordinal logistic regression of the mRS at 6 months, adjusted for minimisation variables. Primary and safety analyses were done according to the patient's treatment allocation. The trial is registered with the Australian New Zealand Clinical Trials Registry, ACTRN12611000774921.
Findings
Between Jan 11, 2013, and June 30, 2019, 1280 patients were recruited in Australia (n=532), New Zealand (n=42), and Vietnam (n=706), of whom 642 were randomly assigned to fluoxetine and 638 were randomly assigned to placebo. Mean duration of trial treatment was 167 days (SD 48·1). At 6 months, mRS data were available in 624 (97%) patients in the fluoxetine group and 632 (99%) in the placebo group. The distribution of mRS categories was similar in the fluoxetine and placebo groups (adjusted common odds ratio 0·94, 95% CI 0·76–1·15; p=0·53). Compared with patients in the placebo group, patients in the fluoxetine group had more falls (20 [3%] vs seven [1%]; p=0·018), bone fractures (19 [3%] vs six [1%]; p=0·014), and epileptic seizures (ten [2%] vs two [<1%]; p=0·038) at 6 months.
Interpretation
Oral fluoxetine 20 mg daily for 6 months after acute stroke did not improve functional outcome and increased the risk of falls, bone fractures, and epileptic seizures. These results do not support the use of fluoxetine to improve functional outcome after stroke
Longitudinal physical activity changes in adolescents: Ho Chi Minh City Youth Cohort
Purpose: This study aimed to describe the 5-yr longitudinal change in moderate-to-vigorous physical activity (MVPA) among urban adolescents in Ho Chi Minh City, Vietnam, and to identify individual, family, and environmental factors associated with changes in MVPA. Methods: The Ho Chi Minh City Youth Cohort is a 5-yr longitudinal cohort with systematic random sampling of 759 students (48% boys) from 18 junior high schools in Ho Chi Minh City, conducted from 2004 to 2009. All measures were taken on five separate occassions. MVPA was assessed by self-report and accelerometry. Data were analyzed using multilevel linear regression models with estimation by generalized linear latent and mixed models. Results: Overall, after adjusting for covariates, students' accelerometer-based MVPA reduced 38% per annum (rate ratio = 0.62, 95% confidence interval (CI) = 0.59-0.64). Boys spent 2.9 times more in MVPA (rate ratio = 2.94, 95% CI = 2.63-3.22) than their female peers. Compared with normal-weight adolescents, overweight and obese adolescents were doing 40% (rate ratio = 0.60, 95% CI = 0.53, 0.67) less MVPA. Conclusions: MVPA significantly declined among Vietnamese adolescents with age. This finding is similar to those reported among Western adolescents and suggests that strategies to promote physical activity in adolescents are a priority in Vietnam because economic transitioning potentially increases the risk of adopting unhealthy lifestyle behaviors associated with obesity and chronic diseases