Supervision of Nonlinear Networked Control Systems Under Network Constraints

International audienceThe remote supervision for a class of nonlinear systems in the presence of additive disturbances and measurement noises is considered in this paper. The communication network may introduce time delays while exchanging data among sites connected to the network medium (i.e., the data acquisition site and the remote plant site). Two different approaches are presented in this paper. The first one uses a conventional estimator-based predictor when the uncertainties are supposed to be known. In the case of unknown but bounded uncertainties by known bounds, an interval estimation-based predictor evaluating the set of admissible values for the state is investigated. The state prediction techniques are used to compensate the effect of network-induced delays. Simulation results are introduced to illustrate the efficiency of the proposed techniques

Resilient State Estimation for Nonlinear Discrete-Time Systems via Input and State Interval Observer Synthesis

This paper addresses the problem of resilient state estimation and attack reconstruction for bounded-error nonlinear discrete-time systems with nonlinear observations/ constraints, where both sensors and actuators can be compromised by false data injection attack signals/unknown inputs. By leveraging mixed-monotone decomposition of nonlinear functions, as well as affine parallel outer-approximation of the observation functions, along with introducing auxiliary states to cancel out the effect of the attacks/unknown inputs, our proposed observer recursively computes interval estimates that by construction, contain the true states and unknown inputs of the system. Moreover, we provide several semi-definite programs to synthesize observer gains to ensure input-to-state stability of the proposed observer and optimality of the design in the sense of minimum $\mathcal{H}_{\infty}$ gain.Comment: 7 page

Interval estimation of switched Takagi-Sugeno systems with unmeasurable premise variables

International audienceThis paper deals with interval observers design for nonlinear switched systems. The nonlinear modes are represented by the Takagi-Sugeno (T-S) fuzzy models with premise variables depending on unmeasurable terms, e.g. the state vector. This T-S structure can be used to represent exactly a nonlinear switched system in a compact set of the state space. The introduced method in this paper allows to compute the lower and upper bounds of the system state under the assumption that the disturbances as well as the measurement noises are unknown but bounded. First, the stability conditions of the proposed T-S interval observers are developed via Linear Matrix Inequality (LMI) formulations to ensure the convergence of the nonnegative observation error dynamics. Then, changes of coordinates are employed to relax the restrictive requirement of nonnegativity constraints. Theoretical results are applied to a numerical example to illustrate the effectiveness of the proposed method

Continuous-discrete time observer design for Lipschitz systems with sampled measurements

International audienceThis technical note concerns observer design for Lipschitz nonlinear systems with sampled output. Using reachability analysis, an upper approximation of the attainable set is given. When this approximation is formulated in terms of a convex combination of linear mappings, a sufficient condition is given in terms of linear matrix inequalities (LMIs) which can be solved employing an LMIs solver. This novel approach seems to be an efficient tool to solve the problem of observer synthesis for a class of Lipschitz systems of small dimensions

Primary Evaluation on Growth Performances of Stress Negative Piétrain Pigs Raised in Hai Phong Province of Vietnam

peer reviewedThe present study was carried out on 19 stress negative Piétrain pigs (Pietrain ReHal), consisting of 13 gilts and 6 young boars imported from Belgium, raised in the livestock farm of Dong Hiep (Hai Phong) in order to evaluate growth performances and their adaptability in the North of Vietnam. Results showed that the average body weight of the whole herd at 2, 4, 5.5, and 8.5 months old was 19.05, 51.05, 85.82, and 119.47 kg, respectively. During the growing periods, except the first stage, the male grew faster than the female and the pigs of the CT genotype grew faster than those of CC genotype although the difference was not significant (P>0.05). The average daily gain (ADG) was 528.56 grams for the whole herd. The ADG was higher for the male (546.48 grams) than for the female (520.29 grams), and its was higher for the CT than the CC, but the difference was not statistically significant (P>0.05). The feed conversion ratio (FCR) was 2.69 kg. The estimated lean percentage at 8.5 months old was 64.08%. The results indicate that Piétrain stress negative pigs could develop well on the farm conditions in Hai Phong, Vietnam

Autologous Transplantation of Adipose-Derived Stem Cells to Treat Acute Spinal Cord Injury: Evaluation of Clinical Signs, Mental Signs, and Quality of Life

BACKGROUD: Spinal cord injury (SCI) is damage that can cause a temporary or permanent change in spinal cord functions AIM: This work evaluates clinical signs, mental signs, and quality of life (QoL) after autologous adipose-derived stem cells (ADSCs) transplantation to treat acute spinal cord injury (SCI). MATERIAL AND METHODS: In this study, 47 SCI patients were recruited and divided into two groups: intervention and control. ADSCs were isolated and cultured under the cell culture quality control procedure. All patients in both groups underwent neurosurgery with or without ADSC transplantation. The recovery regarding neurological muscle, QoL, neurogenic bladder, and mental improvement was assessed after transplantation. RESULTS: All patients had improved in terms of motor function, bladder function, and daily living. No patients reported any side effect. MRI imaging showed significant changes in the lesion length of the spinal canal and the thickening of the spinal cord. Mental improvement was highest at six months after transplantation and lowest at one month after transplantation. The proportion of patients whose quality of life improved after treatment was 100%, while 80% of patients were satisfied with treatment outcomes. CONCLUSIONS: Thus, our data suggested that ADSCs transplantation was safe and effective for the treatment of SCI patients. Neurological muscle and neurogenic bladder were improved significantly after transplantation

Spatiotemporal evolution of SARS-CoV-2 Alpha and Delta variants during large nationwide outbreak of COVID-19, Vietnam, 2021

We analyzed 1,303 SARS-CoV-2 whole-genome sequences from Vietnam, and found the Alpha and Delta variants were responsible for a large nationwide outbreak of COVID-19 in 2021. The Delta variant was confined to the AY.57 lineage and caused >1.7 million infections and >32,000 deaths. Viral transmission was strongly affected by nonpharmaceutical interventions

Safety and efficacy of fluoxetine on functional outcome after acute stroke (AFFINITY): a randomised, double-blind, placebo-controlled trial

Background Trials of fluoxetine for recovery after stroke report conflicting results. The Assessment oF FluoxetINe In sTroke recoverY (AFFINITY) trial aimed to show if daily oral fluoxetine for 6 months after stroke improves functional outcome in an ethnically diverse population. Methods AFFINITY was a randomised, parallel-group, double-blind, placebo-controlled trial done in 43 hospital stroke units in Australia (n=29), New Zealand (four), and Vietnam (ten). Eligible patients were adults (aged ≥18 years) with a clinical diagnosis of acute stroke in the previous 2–15 days, brain imaging consistent with ischaemic or haemorrhagic stroke, and a persisting neurological deficit that produced a modified Rankin Scale (mRS) score of 1 or more. Patients were randomly assigned 1:1 via a web-based system using a minimisation algorithm to once daily, oral fluoxetine 20 mg capsules or matching placebo for 6 months. Patients, carers, investigators, and outcome assessors were masked to the treatment allocation. The primary outcome was functional status, measured by the mRS, at 6 months. The primary analysis was an ordinal logistic regression of the mRS at 6 months, adjusted for minimisation variables. Primary and safety analyses were done according to the patient's treatment allocation. The trial is registered with the Australian New Zealand Clinical Trials Registry, ACTRN12611000774921. Findings Between Jan 11, 2013, and June 30, 2019, 1280 patients were recruited in Australia (n=532), New Zealand (n=42), and Vietnam (n=706), of whom 642 were randomly assigned to fluoxetine and 638 were randomly assigned to placebo. Mean duration of trial treatment was 167 days (SD 48·1). At 6 months, mRS data were available in 624 (97%) patients in the fluoxetine group and 632 (99%) in the placebo group. The distribution of mRS categories was similar in the fluoxetine and placebo groups (adjusted common odds ratio 0·94, 95% CI 0·76–1·15; p=0·53). Compared with patients in the placebo group, patients in the fluoxetine group had more falls (20 [3%] vs seven [1%]; p=0·018), bone fractures (19 [3%] vs six [1%]; p=0·014), and epileptic seizures (ten [2%] vs two [<1%]; p=0·038) at 6 months. Interpretation Oral fluoxetine 20 mg daily for 6 months after acute stroke did not improve functional outcome and increased the risk of falls, bone fractures, and epileptic seizures. These results do not support the use of fluoxetine to improve functional outcome after stroke