Conference Summary - Florida\u27s Future in the Space Age

During the past year and a half as Chairman of THE FLORIDA COUNCIL OF 100, we have, through our Scientific and Technical Higher Education Committee, made extensive studies on the needs of higher education as Florida walks through the door of America\u27s Space. Our work in the fields of attracting new industry into the state end co-ordinating our effort with State and Federal agencies, Boards, Bureaus and Commissions entitles us, I believe, to speak with some authority on the importance of improving an already fine university system

ANNz: estimating photometric redshifts using artificial neural networks

We introduce ANNz, a freely available software package for photometric redshift estimation using Artificial Neural Networks. ANNz learns the relation between photometry and redshift from an appropriate training set of galaxies for which the redshift is already known. Where a large and representative training set is available ANNz is a highly competitive tool when compared with traditional template-fitting methods. The ANNz package is demonstrated on the Sloan Digital Sky Survey Data Release 1, and for this particular data set the r.m.s. redshift error in the range 0 < z < 0.7 is 0.023. Non-ideal conditions (spectroscopic sets which are small, or which are brighter than the photometric set for which redshifts are required) are simulated and the impact on the photometric redshift accuracy assessed.Comment: 6 pages, 6 figures. Replaced to match version accepted by PASP (minor changes to original submission). The ANNz package may be obtained from http://www.ast.cam.ac.uk/~aa

Large-scale wind-tunnel tests of descent performance of an airplane model with a tilt wing and differential propeller thrust

Wind tunnel tests of wing stall, performance, and longitudinal stability & control of large model v/stol tilt wing transport aircraf

Statistical considerations in a systematic review of proxy measures of clinical behaviour

Peer reviewedPublisher PD

Forces generated during stretch in the heart of the lobster Homarus americanus are anisotropic and are altered by neuromodulators

Mechanical and neurophysiological anisotropies mediate three-dimensional responses of the heart of Homarus americanus. Although hearts in vivo are loaded multi-axially by pressure, studies of invertebrate cardiac function typically use uniaxial tests. To generate whole-heart length-tension curves, stretch pyramids at constant lengthening and shortening rates were imposed uniaxially and biaxially along longitudinal and transverse axes of the beating whole heart. To determine whether neuropeptides that are known to modulate cardiac activity in H. americanus affect the active or passive components of these length-tension curves, we also performed these tests in the presence of SGRNFLRFamide (SGRN) and GYSNRNYLRFamide (GYS). In uniaxial and biaxial tests, both passive and active forces increased with stretch along both measurement axes. The increase in passive forces was anisotropic, with greater increases along the longitudinal axis. Passive forces showed hysteresis and active forces were higher during lengthening than shortening phases of the stretch pyramid. Active forces at a given length were increased by both neuropeptides. To exert these effects, neuropeptides might have acted indirectly on the muscle via their effects on the cardiac ganglion, directly on the neuromuscular junction, or directly on the muscles. Because increases in response to stretch were also seen in stimulated motor nerve-muscle preparations, at least some of the effects of the peptides are likely peripheral. Taken together, these findings suggest that flexibility in rhythmic cardiac contractions results from the amplified effects of neuropeptides interacting with the length-tension characteristics of the heart

"Bacterial Meningitis in children and adolescents: an observational study based on the national surveillance system"

BACKGROUND: Bacterial meningitis is a group of life threatening infections that mostly affect children and adolescents, and may be the cause of severe neurological sequelae. Cuba has implemented massive vaccination programmes against both Neisseria meningitidis (serogroup C in 1979 and B in 1987), and Haemophilus influenzae type b (1999), two of the main causal pathogens. We described and discussed some epidemiological aspects of the current status of bacterial meningitis to learn from the Cuban experience. METHODS: A nationwide observational study on children and adolescents from 1 to 18 years old was carried out from 1998 to 2003, estimating the incidence and case-fatality rate by age group and causal pathogens, as well as the seasonality and frequency of overcrowded dormitories. The association between disease and attendance to day care centres or boarding schools was estimated by using relative risk (Chi-squared test and Fisher Exact Test). RESULTS: The overall number of cases was 1023; the incidence ranged from 3.4 to 8.5 per 100 000 population, with the higher figures in children 1–5 years old (16.8 per 100 000 population). Streptococcus pneumoniae, Haemophilus influenzae type b and Neisseria meningitidis serogroup B were the main identified agents. The average case-fatality rate was 10.5% and the most lethal agents were Streptococcus pneumoniae (27%) and Haemophilus influenzae type b (10.7%). Overall percentage of cases who slept in overcrowded dormitories was 15%, reaching 30.6% in adolescents. Seasonality was only evident among meningococcal meningitis cases between September–October. The attendance to boarding high school showed an association with disease only in 1998 and 1999 (RR = 2.1; p > 0.05). CONCLUSION: The highest incidence of bacterial meningitis was observed among children from 1–5 years old. Pneumococcus was both the leading causal and the most lethal agent. Sleeping in overcrowded dormitories was more frequent among adolescents. No strong association was observed between the bacterial meningitis and attendance to day care centres or boarding schools. The incidence of bacterial meningitis in Cuba is declining after massive vaccination programmes against Neisseria meningitidis serogroup B and C and Haemophilus influenzae type b through a national immunisation program

On almost randomizing channels with a short Kraus decomposition

For large d, we study quantum channels on C^d obtained by selecting randomly N independent Kraus operators according to a probability measure mu on the unitary group U(d). When mu is the Haar measure, we show that for N>d/epsilon^2$, such a channel is epsilon-randomizing with high probability, which means that it maps every state within distance epsilon/d (in operator norm) of the maximally mixed state. This slightly improves on a result by Hayden, Leung, Shor and Winter by optimizing their discretization argument. Moreover, for general mu, we obtain a epsilon-randomizing channel provided N > d (\log d)^6/epsilon^2$. For d=2^k (k qubits), this includes Kraus operators obtained by tensoring k random Pauli matrices. The proof uses recent results on empirical processes in Banach spaces.Comment: We added some background on geometry of Banach space

A Cosmic Relation between Extinction and Star Formation

We study the relation between the star formation intensity of galaxies and the extinction by dust of their emitted light. We employ a detailed statistical analysis of Hubble Deep Field North data to show a clear positive correlation between the extinction and star formation intensity at all epochs from redshift 0.4 to 6.5. The extinction evidently increases with time for a given star formation intensity, consistent with the expected increase in the metallicity with time. Our observational results are well fitted at all epochs by a double power-law model with a fixed shape that simply shifts with redshift. The correlation between the extinction and the star formation intensity can be interpreted by combining two other trends: the correlation between the star formation rate and the gas content of galaxies, and the evolution of the dust-to-gas ratio in galaxies. If we assume that Kennicutt's observed relation for the former is valid at each redshift, then our findings imply an interesting variation in the dust-to-gas ratio in galaxies within each epoch and with time, and suggest new ways to investigate the cosmic evolution of this quantity.Comment: 5 pages, 5 figures, MNRAS Letters, revised versio

Community acquired bacterial meningitis in Cuba: a follow up of a decade

BACKGROUND: Community acquired Bacterial Meningitis (BM) remains a serious threat to global health. Cuban surveillance system for BM allowed to characterize the main epidemiological features of this group of diseases, as well as to assess the association of some variables with mortality. Results of the BM surveillance in Cuba are presented in this paper. METHODS: A follow up of BM cases reported to the Institute "Pedro Kourí" by the National Bacterial Meningitis Surveillance System from 1998 to 2007 was completed. Incidence and case-fatality rate (CFR) were calculated. Univariate analysis and logistic regression were used to elucidate associated factors to mortality comparing death versus survival. Relative Risk (RR) or odds ratio and its 95% confidence interval (CI 95%) were estimated, using either a Chi-squared Test or Fisher's Exact Test as appropriate. A Holt-Winters model was used to assess seasonality. RESULTS: 4 798 cases of BM (4.3 per 100 000 population) were reported, with a decreasing trend of the incidence. Highest incidence was observed in infants and elderly. Overall CFR reached 24.1% affecting mostly older adults. S. pneumoniae (23.6%), N. meningitidis(8.2%) and H. influenzaetype b (6.0%) were the main causative agents. Males predominate in the incidence. Highest incidence and CFR were mainly clustered in the centre of the island. The univariate analysis did not show association between delayed medical consultation (RR = 1.20; CI = 1.07-1.35) or delayed hospitalization (RR = 0.98; CI = 0.87-1.11) and the fatal outcome. Logistic regression model showed association of categories housewife, pensioned, imprisoned, unemployed, S. peumoniae and other bacteria with mortality. Seasonality during September, January and March was observed. CONCLUSIONS: The results of the National Program for Control and Prevention of the Neurological Infectious Syndrome evidenced a reduction of the BM incidence, but not the CFR. Multivariate analysis identified an association of mortality with some societal groups as well as with S. peumoniae

Tourism and the smartphone app: capabilities, emerging practice and scope in the travel domain.

Based on its advanced computing capabilities and ubiquity, the smartphone has rapidly been adopted as a tourism travel tool.With a growing number of users and a wide varietyof applications emerging, the smartphone is fundamentally altering our current use and understanding of the transport network and tourism travel. Based on a review of smartphone apps, this article evaluates the current functionalities used in the domestic tourism travel domain and highlights where the next major developments lie. Then, at a more conceptual level, the article analyses how the smartphone mediates tourism travel and the role it might play in more collaborative and dynamic travel decisions to facilitate sustainable travel. Some emerging research challenges are discussed