16 research outputs found
Comparative in vitro study of the antimicrobial activities of different commercial antibiotic products of vancomycin
Análisis de los principales desafíos de la empresa Prodesa en la optimización del clima organizacional
Nota. Cuestionario aplicado a la coordinadora de talento humano de la empresa, Nota. Resultados generales 2022, Nota. Valoración de las dimensiones, Nota. La organización Prodesa frente al sector y los mejores lugares para trabajar en el 2022.El presente proyecto de investigación tiene como objetivo principal analizar los desafíos a los que se enfrenta la empresa Prodesa, en su sede de Bogotá, con el propósito de optimizar el clima organizacional. Para esto se llevó a cabo una investigación cualitativa con un enfoque descriptivo – analítico, respaldada por una revisión y análisis documental. La obtención de datos se complementó mediante un cuestionario aplicado a la coordinadora de recursos humanos de la empresa, que proporcionó una visión integral sobre la percepción del clima organizacional en la organización. Concluyendo que los mayores desafíos a los que se enfrenta la organización son la gestión del cambio y el equilibrio entre la vida personal y laboral, así como la comunicación y el liderazgo que son factores relevantes y de alto impacto para la optimización del clima laboral de cualquier organización.The main objective of this research project is to analyze the challenges faced by the company Prodesa, at its headquarters in Bogota, in order to optimize the organizational climate. For this purpose, qualitative research was carried out with a descriptive-analytical approach, supported by a documentary review and analysis. Data collection was complemented by means of a questionnaire applied to the human resources coordinator of the company, which provided a comprehensive view of the perception of the organizational climate in the organization. It was concluded that the greatest challenges faced by the organization are change management and work-life balance, as well as communication and leadership, which are relevant and high-impact factors for the optimization of the work climate of any organization
Standardization in laboratory medicine: Two years’ experience from category 1 EQA programs in Spain
Introduction: Standardization is the ability to obtain interchangeable results leading to same medical interpretation. External quality assessment
(EQA) is the main support of the on-going harmonization initiatives. Aim of study was to evaluate results obtained from two years category 1 EQA
program experience in Spain and determine the impact of applying this type of EQA program on the analytical standardization.
Materials and methods: According to the analytical method, traceability and instrument different groups were established which results were
evaluated by calculating mean, coefficient of variation and percent of deviation to the reference value. Analytical performance specifications used
to the results\u27 evaluation were derived from biological variation for bias and from the inter-laboratory coefficients of variation found in a previous
pilot study.
Results: Only creatinine measured by enzymatic methods gave excellent results, although few laboratories used this method. Creatine kinase and
GGT gave good precision and bias in all, but one instrument studied. For the remaining analytes (ALT, ALP, AST, bilirubin, calcium, chloride, glucose,
magnesium, potassium, sodium, total protein and urate) some improvement is still necessary to achieve satisfactory standardization in our setting.
Conclusions: The two years of category 1 EQA program experience in Spain have manifested a lack of standardization of 17 most frequent biochemistry
tests used in our laboratories. The impact of the information obtained on the lack of standardization is to recommend abandoning methods
such as ALT, AST without exogenous pyridoxal phosphate, Jaffe method for creatinine, and do not use non-commutable calibrators, such as aqueous
solutions for calcium and sodium
Procesos de aplicación conceptual y práctico de la normatividad tributaria en contextos investigativos procedimentales tributarios para el fortalecimiento de las competencias disciplinares y profesionales
La presente investigación planteó como objetivo realizar las memorias con las temáticas investigativas que se desarrollaron en el Seminario de Investigación Aplicada, con el fin de actualizar en los participantes y fortalecer sus conocimientos específicos en materia tributaria con base en los temas investigativos dispuestos y orientados por cada docente desde su inicio, elaboración, construcción y presentación ante los docentes evaluadores. Los trabajos cumplen su fin primordial con es fortalecer con los desarrollos temático de cada módulo visto en el SIA sus capacidades y competencias profesionales especialmente en el contexto tributario, en cumplimiento al requerimiento para otorgar al título de Especialistas en Gerencia Tributaria. Luego las memorias compiladas son el resultado de los trabajos presentados y evaluados oportunamente por cada docente comprometido con la calidad en cuanto a las temáticas investigativas, calidad de los contenidos, talleres teóricos prácticos, elementos metodológicos y de más lineamentos institucionales y del programa.
La importancia de las memorias radica en su contenido el cual desglosa definiciones, conceptos, desarrollos teóricos prácticos, constituyéndose en un ejemplar de consulta investigativa en áreas de conocimiento fiscal y tributario en el marco de la Ley 1819 de 2016 y sus decretos reglamentarios, en síntesis al interior encontraremos fundamentos teóricos prácticos, procedimentales y resolutivos de casos especiales de Gravamen a los Movimientos Financieros, Monotributo, Renta Personas Naturales, Renta Personas Jurídicas, Procedimiento Tributario, Impuestos Distritales, Normas internacionales de Información Financiera Pymes, entre otros temas
La investigación formativa en ciencias empresariales: .Experiencias de investigación formativa POLIPIF
El material propuesto en el libro resume gran parte de la calidad de los trabajos presentados y la evolución en el desarrollo de las capacidades de los estudiantes en un contexto actual, complejo y retador, que refleja la realidad de las organizaciones actuales sobre escenarios estratégicos y manejo de situaciones complejas, para que, cuando lleguen a ser empleados o emprendedores, sepan afrontar cada paso hacia el cambio
Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study
Funder: European Society of Intensive Care Medicine; doi: http://dx.doi.org/10.13039/501100013347Funder: Flemish Society for Critical Care NursesAbstract: Purpose: Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in adult ICU patients. Methods: International 1-day point-prevalence study; follow-up for outcome assessment until hospital discharge (maximum 12 weeks). Factors associated with ICU-acquired pressure injury and hospital mortality were assessed by generalised linear mixed-effects regression analysis. Results: Data from 13,254 patients in 1117 ICUs (90 countries) revealed 6747 pressure injuries; 3997 (59.2%) were ICU-acquired. Overall prevalence was 26.6% (95% confidence interval [CI] 25.9–27.3). ICU-acquired prevalence was 16.2% (95% CI 15.6–16.8). Sacrum (37%) and heels (19.5%) were most affected. Factors independently associated with ICU-acquired pressure injuries were older age, male sex, being underweight, emergency surgery, higher Simplified Acute Physiology Score II, Braden score 3 days, comorbidities (chronic obstructive pulmonary disease, immunodeficiency), organ support (renal replacement, mechanical ventilation on ICU admission), and being in a low or lower-middle income-economy. Gradually increasing associations with mortality were identified for increasing severity of pressure injury: stage I (odds ratio [OR] 1.5; 95% CI 1.2–1.8), stage II (OR 1.6; 95% CI 1.4–1.9), and stage III or worse (OR 2.8; 95% CI 2.3–3.3). Conclusion: Pressure injuries are common in adult ICU patients. ICU-acquired pressure injuries are associated with mainly intrinsic factors and mortality. Optimal care standards, increased awareness, appropriate resource allocation, and further research into optimal prevention are pivotal to tackle this important patient safety threat
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Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study
Funder: European Society of Intensive Care Medicine; doi: http://dx.doi.org/10.13039/501100013347Funder: Flemish Society for Critical Care NursesAbstract: Purpose: Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in adult ICU patients. Methods: International 1-day point-prevalence study; follow-up for outcome assessment until hospital discharge (maximum 12 weeks). Factors associated with ICU-acquired pressure injury and hospital mortality were assessed by generalised linear mixed-effects regression analysis. Results: Data from 13,254 patients in 1117 ICUs (90 countries) revealed 6747 pressure injuries; 3997 (59.2%) were ICU-acquired. Overall prevalence was 26.6% (95% confidence interval [CI] 25.9–27.3). ICU-acquired prevalence was 16.2% (95% CI 15.6–16.8). Sacrum (37%) and heels (19.5%) were most affected. Factors independently associated with ICU-acquired pressure injuries were older age, male sex, being underweight, emergency surgery, higher Simplified Acute Physiology Score II, Braden score 3 days, comorbidities (chronic obstructive pulmonary disease, immunodeficiency), organ support (renal replacement, mechanical ventilation on ICU admission), and being in a low or lower-middle income-economy. Gradually increasing associations with mortality were identified for increasing severity of pressure injury: stage I (odds ratio [OR] 1.5; 95% CI 1.2–1.8), stage II (OR 1.6; 95% CI 1.4–1.9), and stage III or worse (OR 2.8; 95% CI 2.3–3.3). Conclusion: Pressure injuries are common in adult ICU patients. ICU-acquired pressure injuries are associated with mainly intrinsic factors and mortality. Optimal care standards, increased awareness, appropriate resource allocation, and further research into optimal prevention are pivotal to tackle this important patient safety threat
Recommended from our members
Correction to: Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study
The original version of this article unfortunately contained a mistake
CARACTERIZACIÓN CLÍNICA DE PACIENTES CON VITILIGO EN UN HOSPITAL UNIVERSITARIO EN COLOMBIA
Introduccion y objetivo: El vitíligo es una hipomelanosis adquirida que se manifiesta clínicamente por la aparición progresiva de máculas acrómicas en la piel y cabello de áreas afectadas. La prevalencia mundial es de 0,5% a 2%. El objetivo, es dar a conocer la caracterización dermatológica clínica y terapéutica de los pacientes del Hospital Universitario de Santander. Métodos: Estudio observacional, descriptivo de corte transversal retrospectivo. La población estudio fueron pacientes con Vitíligo que ingresaron a un hospital universitario de Colombia entre el período comprendido entre los años 2012-2016 en pacientes mayores de 13 años que ingresen a la institución. Resultados: Se analizaron 64 pacientes que tenían una mediana de edad de 41,1 años, la mediana de tiempo de evolución de la enfermedad fue de 12 meses, con distribución de sexo con relación 1:!; en la caracterización clínica 100% de los pacientes presentaron hipopigmentación cutánea; la localización de las lesiones fue en miembros superiores 51.56%, cabeza y cuello 43.75%, miembros inferiores con 28.13%, tórax 18.75%, región perineal 9.38% y abdomen 6.25%. El tratamiento, 62,5% con tacrolimús, 28.13% clobetasol, 3,13% psoralenos + PUVA (fotoquimioterapia), y 1,56% fototerapia. Conclusiones: Las características sociodemográficas encontradas son similares a lo encontrado teóricamente a nivel mundial, la distribución por sexo es similar, la característica clínica general fue la hipopigmentación cutánea, con localización más frecuente en miembros superiores y el tratamiento fue con tacrolimús
Critical appraisal and meta-analysis of biological variation estimates for kidney related analytes
Postponed access: the file will be available after 2021-10-03Objective: Kidney markers are some of the most frequently used laboratory tests in patient care, and correct clinical decision making depends upon knowledge and correct application of biological variation (BV) data. The aim of this study was to review available BV data and to provide updated BV estimates for the following kidney markers in serum and plasma; albumin, creatinine, cystatin C, chloride, potassium, sodium and urea.
Content: Relevant studies were identified from a historical BV database as well as by systematic literature searches. Retrieved publications were appraised by the Biological Variation Data Critical Appraisal Checklist (BIVAC). Meta-analyses of BIVAC compliant studies with similar design were performed to deliver global estimates of within-subject (CVI) and between-subject (CVG) BV estimates. Out of the 61 identified papers, three received a BIVAC grade A, four grade B, 48 grade C, five grade D grade and one was not appraised as it did not report numerical BV estimates. Most studies were identified for creatinine (n=48). BV estimates derived from the meta-analysis were in general lower than previously reported estimates for all analytes except urea. For some measurands, BV estimates may be influenced by age or states of health, but further data are required.
Summary: This review provides updated global BV estimates for kidney related measurands. For all measurands except for urea, these estimates were lower than previously reported.
Outlook: For the measurands analyzed in this review, there are sufficient well-designed studies available to publish a trustworthy estimate of BV. However, for a number of newly appearing kidney markers no suitable data is available and additional studies are required.publishedVersio