A Process for Producing Ice Coverage Marine Information Objects (MIOs) in IHO S-57 Format

While global warming may be opening up more Arctic waters in the summer, ice still infests key shipping lanes in the northern hemisphere during the winter months. To safely navigate these areas, mariners rely on daily ice coverage charts produced by national governmental agencies. Ice charts are primarily issued in paper format or as a fax. However, there is increased interest to ice coverage information on vessel navigation systems such as an Electronic Chart and Display Information Systems (ECDIS). However, to do so, the ice information must be provided as a separate layer of information to the Electronic Navigational Chart (ENC)

A Process for Producing Ice Coverage Marine Information Objects (MIOs) in IHO S-57 format

While global warming may be opening up more Arctic waters in the summer, ice still infests key shipping lanes in the northern hemisphere during the winter months. To safely navigate these areas, mariners rely on daily ice coverage charts produced by national governmental agencies. Ice charts are primarily issued in paper format or as a fax. However, there is increased interest to ice coverage information on vessel navigation systems such as an Electronic Chart and Display Information Systems (ECDIS). However, to do so, the ice information must be provided as a separate layer of information to the Electronic Navigational Chart (ENC).Mientras que un calentamiento global puede aumentar la extension de las aguas ârticas en verano, el hieio sigue infestando las dénotas maritimas en el hemisferio septentrional durante los meses de invierno. Para navegar en estas zonas de forma segura, los navegantes conffan en las cartas de cobertura diaria del hielo producidas por agendas gubernamentales nacionales. Las cartas del hielo son editadas principaimente en formato impreso o como fax. Sin embargo, hay un interés creciente por la informaciôn de cobertura del hielo en los sistemas de navegaciôn de los buques, como por ejemplo en los Sistemas de Presentaciôn de las Cartas Electrônicas y de Informaciôn (ECDIS). Sin embargo, para producirlas, tiene que proporcionarse la informaciôn sobre el hielo como una serie de informaciôn separada para la Carta Electrônica de Navegaciôn (ENC).Bien que le réchauffement global puisse faire enfler les eaux arctiques en été, les glaces envahissent toujours les principaux couloirs de navigation dans l'hémisphère, pendant la saison hivernale. Afin de naviguer en toute sécurité dans ces zones, les navigateurs se fient aux cartes des glaces produites quotidiennement par les agences gouvernementales nationales. Les cartes des glaces sont essentiellement communiquées sous forme imprimée ou de télécopie. On note cependant un regain d’intérêt pour les informations sur la couverture des glaces, dans des systèmes de navigation maritime tel que l ’ECDIS (système de visualisation des cartes électroniques et d'information). Toutefois, pour ce faire, les renseignements sur les glaces doivent être transmis, en tant que « niveau » d’information distinct, aux Cartes électroniques de navigation (ENC)

Establishing an EU-China consortium on traditional Chinese medicine research.

Traditional Chinese medicine (TCM) is widely used in the European Union (EU) and attracts intense research interests from European scientists. As an emerging area in Europe, TCM research requires collaboration and coordination of actions. Good Practice in Traditional Chinese Medicine Research in the Post-genomic Era, also known as GP-TCM, is the first ever EU-funded 7th Framework Programme (FP7) coordination action, aiming to inform the best practice and harmonise research on the safety and efficacy of TCM through interdisciplinary exchange of experience and expertise among clinicians and scientists. With its increasingly large pool of expertise across 19 countries including 13 EU member states, Australia, Canada, China, Norway, Thailand and the USA, the consortium provides forums and collaboration platforms on quality control, extraction technology, component analysis, toxicology, pharmacology and regulatory issues of Chinese herbal medicine (CHM), as well as on acupuncture studies, with a particular emphasis on the application of a functional genomics approach. The project officially started in May 2009 and by the time of its conclusion in April 2012 a Europe-based academic society dedicated to TCM research will be founded to carry on the mission of GP-TCM.RIGHTS : This article is licensed under the BioMed Central licence at http://www.biomedcentral.com/about/license which is similar to the 'Creative Commons Attribution Licence'. In brief you may : copy, distribute, and display the work; make derivative works; or make commercial use of the work - under the following conditions: the original author must be given credit; for any reuse or distribution, it must be made clear to others what the license terms of this work are

PENGELOLAAN USAHA MIKRO KECIL DAN MENENGAH (UMKM) BERBASIS MEDIA DIGITAL

This research was conducted in Harapan Mulya Village, RT 007/RW 001, Bekasi City. The research was conducted as a form of student/I community service, namely PMD-MBKM activities related to digital-based management of micro, small and medium enterprises (MSMEs). We found that the dominant problem occurred in Harapan Mulya Village RT 007, namely the decline in income for MSMEs in Harapan Mulya Village which occurred due to the last Covid-19 pandemic. The problem of decreasing income is also our concern, therefore we have created a work program that includes entrepreneurship, re-branding, and digital- based, this aims to redevelop the economy or people's income in Harapan Mulya Village. In this study, we obtained data from observations, interviews, and documentation using qualitative methods because we gained in-depth understanding, developed the theory used, and described reality. This research is also the subject of similar research. Keywords:    Covid- 19 , PMD, MBKM, UMKM, Rebranding, Digital Media, Social Media     ABSTRAK   Penelitian ini dilaksanakan di wilayah Desa Harapan Mulya RT 007/RW 001 Kota Bekasi. Penelitian dilakukan sebagai bentuk pengabdian mahasiswa/i kepada masyarakat yaitu dengan kegiatan PMD-MBKM yang terkait dengan pengelolaan usaha mikro kecil dan menengah (UMKM) berbasis digital. Kami menemukan permasalahan yang dominan terjadi di Desa Harapan Mulya RT 007 yaitu penurunan pendapatan terhadap UMKM yang terdapat di Desa Harapan Mulya yang terjadi akibat adanya pandemik Covid-19 lalu. Permasalahan penurunan pendapatan ini turut menjadi perhatian kami, maka dari itu kami membuat program kerja yang meliputi kewirausahaan, re-branding, dan berbasis digital, hal ini bertujuan untuk mengembangkan kembali perekonomian atau pendapatan masyarakat di Desa Harapan Mulya. Pada penelitian ini kami memperoleh data dari hasil observasi, wawancara, dan dokumentasi dengan menggunakan metode kualitatiif karena memperoleh pemahaman secara mendalam, mengembangkan teori yang dipakai, serta mendeskripsikan realitas. Penelitian ini juga menjadi bahan penelitian serupa.   Kata  Kunci:    Covid-19,  PMD,  MBKM,  UMKM,     Re-branding,  Media  Digital,  Media  Sosia

Modelling complex cracks with finite elements: a kinematically enriched constitutive model

A continuum constitutive framework with embedded cohesive interface model is presented to describe the failure of quasi-brittle materials. Both cohesive behaviour for cracking inside the fracture process zone and elastic bulk behaviour are treated at integration points making implementation straightforward. In this sense, the proposed approach is simpler than existing ones that focus on element enrichments, such as the extended finite element method, while share similarities with smeared crack models, and offers the capability to correctly model quasi-brittle failure in post-peak regime at constitutive level. In this work, the formulation is introduced, numerical algorithms described and static and dynamic fracture simulations with complex crack patterns are conducted to demonstrate the capability and advantage of the proposed approach.ARC DP140100945, ARC FT140100408, ARC DE 15010170

Modelling complex cracks with finite elements: a kinematically enriched constitutive model

A continuum constitutive framework with embedded cohesive interface model is presented to describe the failure of quasi-brittle materials. Both cohesive behaviour for cracking inside the fracture process zone and elastic bulk behaviour are treated at integration points making implementation straightforward. In this sense, the proposed approach is simpler than existing ones that focus on element enrichments, such as the extended finite element method, while share similarities with smeared crack models, and offers the capability to correctly model quasi-brittle failure in post-peak regime at constitutive level. In this work, the formulation is introduced, numerical algorithms described and static and dynamic fracture simulations with complex crack patterns are conducted to demonstrate the capability and advantage of the proposed approach.ARC DP140100945, ARC FT140100408, ARC DE 15010170

Estado da arte da temática de Internacionalização do Ensino Superior e de suas Instituições: mapeamento sistemático da produção global

Diante da realidade do aumento de estudos no que tange à Internacionalização do Ensino Superior, vê-se a necessidade de realizar o estudo a respeito do estado da arte do tema, com o objetivo de captar, sistematizar e analisar a produção científica sobre a temática da Internacionalização do Ensino Superior. Para atingir este objetivo foi realizado um estudo em 58 artigos, sendo todos voltados ao tema central citado acima, dos quais foram classificados a fim de maior organização e clareza dos dados, em 4 seções, são elas: (i) ano de publicação; (ii) autor(es) responsáveis pelo estudo; (iii) país de publicação; (iv) artigos publicados no International Journal of Educational Management. Foram encontradas nas categorias de análise futura, ou seja, pesquisas futuras, as seguintes lacunas: (i) estudos que partam de amostras maiores e diversificadas, para melhor representatividade da Internacionalização do Ensino Superior; (ii) estudos que tratam dos fatores decisivos para indivíduos no contexto da internacionalização de estudantes; (iii) estudos que tragam contribuição metodológica por meio de pesquisas mistas dentro da área de international education; (iv) estudos que abordem os esforços individuais de pesquisadores para a internacionalização, bem como as parcerias internacionais entre IES, com foco em particularidades culturais. Além disso, também foram analisados os autores mais citados.Palavras-chave: internacionalização no ensino superior; ensino superior; estratégia organizacional; educação internacional

Characterisation of Connexin Expression and Electrophysiological Properties in Stable Clones of the HL-1 Myocyte Cell Line

The HL-1 atrial line contains cells blocked at various developmental stages. To obtain homogeneous sub-clones and correlate changes in gene expression with functional alterations, individual clones were obtained and characterised for parameters involved in conduction and excitation-contraction coupling. Northern blots for mRNAs coding for connexins 40, 43 and 45 and calcium handling proteins (sodium/calcium exchanger, L- and T-type calcium channels, ryanodine receptor 2 and sarco-endoplasmic reticulum calcium ATPase 2) were performed. Connexin expression was further characterised by western blots and immunofluorescence. Inward currents were characterised by voltage clamp and conduction velocities measured using microelectrode arrays. The HL-1 clones had similar sodium and calcium inward currents with the exception of clone 2 which had a significantly smaller calcium current density. All the clones displayed homogenous propagation of electrical activity across the monolayer correlating with the levels of connexin expression. Conduction velocities were also more sensitive to inhibition of junctional coupling by carbenoxolone (∼80%) compared to inhibition of the sodium current by lidocaine (∼20%). Electrical coupling by gap junctions was the major determinant of conduction velocities in HL-1 cell lines. In summary we have isolated homogenous and stable HL-1 clones that display characteristics distinct from the heterogeneous properties of the original cell line

Enhancing an Automated Braille Writing Tutor

Abstract-The reported work advances the state-of-the-art in assistive technology for the blind by enhancing a low-cost automated tutor designed to teach braille writing skills to visually impaired children using voice feedback. We first provide some background on how the methodology of Intelligent Tutoring Systems correlates to an automated tutor for teaching braille writing skills. We then build on prior work to enhance our automated Braille Writing Tutor in three dimensions: (1) Initial field testing in three different countries; (2) Exploring customization needs for improving relevance in different cultures; and (3) Adding relevant games for increasing motivation. The outcome of this work is an enhanced low-cost tool that can help to increase braille literacy in blind communities around the world. I. INTRODUCTION LMOST 90% of the world's visually impaired people live in developing communities removed from the slate and turned over. Thus, learning to write braille can be difficult for the following reasons. First, children must learn mirror images of all letters, which doubles the alphabet and creates a disparity between the written and read forms of each letter. Second, feedback is delayed until the paper is removed and then flipped over and read. For young children, this delay can make braille conceptually challenging because the act of writing has no immediate feedback. It also takes longer for both the student and the teacher to identify and correct mistakes, and this slows the learning process. Together, these challenges contribute to the problem of illiteracy among the blind; especially in developing communities. Even in developed countries, writing braille with a slate and stylus is still viewed as the simplest and most affordable and portable format for note taking. In fact, some efforts are being made in the USA to renew the interest and skills for writing braille using a slate and stylus. Thus, assistive braille writing technology can have significant impact on millions of lives. We address some of these challenges in learning to write braille through the automated tutor shown in Enhancing an Automated Braille Writing Tuto

Comparative study of the antioxidant and enzyme inhibitory activities of two types of Moroccan Euphorbia entire honey and their phenolic extracts

Honey is a natural food product very famous for its health benefits for being an important source of antioxidant and phenolic compounds. Euphorbia honeys obtained from different regions of Morocco were evaluated for their ability to inhibit acetylcholinesterase, lipoxygenase, tyrosinase and xanthine oxidase activities. Their antioxidant properties were evaluated using the: 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical-scavenging capacity, nitric oxide scavenging activity (NO) and scavenging ability of superoxide anion radical. Then, the phenolic extracts of the same entire honey samples were evaluated by liquid chromatography coupled to diode array detection and mass spectrometry (LC-DAD-MS) and tested for the biological activities previously evaluated on the entire honeys, in order to conduct a comparative study between both (honey and phenolic extracts). The chromatographic profiles for the studied Euphorbia honey extracts were different. Phenolic compounds gallic acid, 4-hydroxybenzoic acid and p-coumaric acid were detected in all samples, whereas kampferol was only present in two samples. Physicochemical parameters and total phenolic content were also determined. Entire honey that recorded the highest rate of phenols was sample M6 (E. resinifera) = 69.25 mg GAE/100 g. On the other hand, the phenolic extracts had better antioxidant and enzyme inhibitory activities than the entire honeys, regardless the monofloral honey type. In conclusion, the studied Euphorbia honeys may have a great potential as antioxidant, anti-inflammatory and anti-tyrosinase sources for pharmaceutical and cosmetic applications.info:eu-repo/semantics/publishedVersio