WHEN THE SACHETS GET MIXED-UP – BENZYDAMINE HYDROCHLORIDE INGESTION

Introdução: O cloridrato de benzidamina é um anti-inflamatório não esteróide com propriedades analgésicas, antipiréticas e antimicrobianas. Caso Clínico: Menino de 4 anos e 8 meses recorreu ao serviço de urgência por agitação psicomotora e alucinações vi- suais, com início cerca de 1 hora após a ingestão acidental de uma saqueta de 500 mg de cloridrato de benzidamina. Ao exa- me objetivo apresentava ataxia, tremor, abalos espasmódicos ocasionais, agitação psicomotora e alucinações visuais. Após lavagem gástrica e administração de carvão ativado, administrou-se haloperidol pelo quadro acentuado de agitação com alucinações visuais. Dada a possibilidade de ocorrência de asfixia por espasmo da musculatura respiratória, foi transferido para um hospital terciário. Apresentou evolução favorável, com alta ao 2º dia de internamento. Discussão: Alerta-se para o risco de confusão na via de administração de apresentações para uso tópico e oral. Sendo a principal manifestação o efeito alucinogénico, a ingestão acidental ou intencional de benzidamina deve ser considerada em quadros psicóticos agudos

Competência humana e digital - fronteiras ao aprender cooperativo

Este artigo discute sobre as competências pedagógicas na educação à distância (EaD), como possibilidade de reflexão reconstrutiva da aprendizagem. Por meio da intercomunicação e da diversidade do saber, em relação às capacidades sempre renovadas do letramento e da fluência digital, visamos oferecer condições para a prática profissional do professor e para desenvolver a competência digital. A inquietação da proposta hermenêutica vem ao encontro da questão das diferenças e da ação processual necessária à constituição das competências de professores para atuarem em diferentes contextos da educação. Concluímos que a combinação de diversas competências da EaD, constitui-se no projetar-se de desafios em contínua transformação às fronteiras do aprender, intrínsecas ao agir socioeducativo.Palavras-chave: Educação à distância. Competência. Fluência digital.Human and digital competence - frontiers by cooperative learningABSTRACTThis article discusses pedagogical competences in distance education (EaD), as a possibility of reconstructive reflection on learning. Through intercommunication and the diversity of knowledge, in relation to the ever renewed capacities of literacy and digital fluency, we aim to offer the conditions to learn the professional practice of the teacher and to develop the digital competence. The uneasiness of the hermeneutic proposal addresses the issue of differences and procedural action necessary to build the competencies of teachers to act in different contexts of education. We conclude that the combination of several EaD skills consists in projecting challenges that are constantly changing to the boundaries of learning, intrinsic to socio-educational activity.Keywords: Distance education. Competence. Digital fluencyCompetencia humana y digital - fronteiras al aprender cooperativoRESUMENEste artículo discute sobre las competencias pedagógicas en la educación a distancia (EaD), como posibilidad de refl exión reconstructiva del aprendizaje. A través de la intercomunicación y de la diversidad del saber, en relación a las capacidades siempre renovadas del alfabetismo y de la fl uencia digital, pretendemos ofrecer condiciones para la práctica profesional del profesor y para desarrollar la competencia digital. La inquietud de la propuesta hermenéutica viene al encuentro de la cuestión de las diferencias y de la acción procesal necesaria para la constitución de las competencias de profesores para actuaren en diferentes contextos de la educación. Concluimos que la combinación de diversas competencias de la EaD, se constituye en el proyectarse de desafíos en continua transformación a las fronteras del aprendizaje, intrínsecas al actuar socioeducativo.Palabras clave: Educación a distancia. Competência. Fluidez digita

Severe acute respiratory syndrome coronavirus 2 seroprevalence among patients with pulmonary tuberculosis

Objective: The objective of this study was to estimate the seroprevalence of severe acute respiratory syndrome coronavirus 2 antibodies in patients with tuberculosis. Methods: This cross-sectional study was conducted at an outpatient tuberculosis clinic in Alvorada, RS, Brazil, with data collection between October and December 2020. Outpatients aged>18 years with active pulmonary tuberculosis, no prior history of coronavirus disease 2019, and no suspected coronavirus disease 2019 were included in the study. Whole blood samples were collected to perform the severe acute respiratory syndrome coronavirus 2 antibodies test. Results: During the study period, 52 patients met the inclusion and were included in the analysis. Severe acute respiratory syndrome coronavirus 2 antibodies were positive in 16 (30.8%) patients. Male sex was more frequent among patients with negative severe acute respiratory syndrome coronavirus 2 antibodies than in patients with positive severe acute respiratory syndrome coronavirus 2 antibodies (86.1 vs. 56.3%, p=0.031). Contact with coronavirus disease 2019 case was more common in patients with positive severe acute respiratory syndrome coronavirus 2 antibodies compared with patients with negative severe acute respiratory syndrome coronavirus 2 antibodies (87.5 vs. 8.3%, p<0.0001). In a multivariate analysis, in a model including the variables such as male sex and contact with coronavirus disease 2019 case, only contact with coronavirus disease 2019 was independently associated with positive severe acute respiratory syndrome coronavirus 2 antibodies (OR 77.0, 95%CI 11.5-512.4, p<0.0001). Conclusion: This study revealed a seroprevalence of 30.8% severe acute respiratory syndrome coronavirus 2 among patients with tuberculosis

Impact of introduction of Xpert MTB/RIF test on tuberculosis (TB) diagnosis in a city with high TB incidence in Brazil

Background Xpert MTB/RIF is increasingly used in many countries as the initial diagnostic test for tuberculosis (TB). Few studies have evaluated the effect of Xpert on TB diagnosis under programmatic conditions in Brazil. The aim of the present study was to evaluate the impact of introduction of Xpert MTB/RIF on TB diagnosis in a city with high TB incidence in Brazil. Methods We included patients evaluated with conventional diagnostic tests during one year before Xpert introduction (pre-Xpert group) and patients evaluated using Xpert during one year after the test introduction (post-Xpert group). Results 620 patients met the inclusion criteria (208 in the pre-Xpert group and 412 in the postXpert group) and were included in the analysis. The time until TB diagnosis was shorter in post-Xpert group (0.7 day, IQR: 0.5–1.0 day) than in pre-Xpert group (2.0 days, IQR: 2.0– 2.0 days) (p<0.0001). Atypical disease characteristics, such as less weight loss, fever, dyspnea, night sweats, and hemoptysis; a negative sputum smear; a negative culture, and a chest X-ray atypical of TB were more common in post-Xpert group than in pre-Xpert group (p<0.0001 for all). Conclusions We found that the implementation of the Xpert MTB/RIF assay, under programmatic conditions, improve and facilitate TB diagnosis, especially in cases with atypical disease manifestations. These results are likely to be generalizable to settings with a similar high TB incidence

Implementation of selective collection of solid wastes in Vale Campus and environmental management in Federal University of Rio Grande do Sul

Decorrente da Legislação Federal e Municipal a Universidade Federal do Rio Grande do Sul implantou a coleta seletiva de seus resíduos, dentro do Programa de Implantação de um Sistema de Gestão Ambiental. A efetivação da coleta se deu através de convênio com a Prefeitura do município de Viamão e a Associação Ecológica Passo Dorneles, para a colaboração recíproca, a fim de promover a elaboração conjunta e a execução de ações para a coleta, a destinação e a triagem adequadas dos resíduos sólidos recicláveis, provenientes do Campus do Vale da UFRGS, com vistas à geração de renda dos integrantes da Associação e, em sentido mais amplo, ao desenvolvimento sustentável e à preservação do meio ambiente. Como resultado temos hoje a destinação de aproximadamente 20 toneladas de material reciclável por mês para a Associação, oriundos das atividades do Campus do Vale da UFRGS.In compliance with Federal and Municipal Legislations, the Federal University of Rio Grande do Sul – UFRGS implemented the selective collection of its wastes under the Environmental Management System Implementation Program. The collection was set up through a cooperation agreement between the city of Viamão and Passo Dorneles Ecologic Association to promote the development and performance of joint actions for the appropriate collection, destination and separation of recyclable solid wastes originated in UFRGS Vale Campus, with the purpose of generating income for the Association members and, in a broader sense, encouraging the sustainable development and preservation of the environment. Today, as a result of the Program, approximately 20 tons per month of recyclable materials from the UFRGS Vale Campus are destined to the Association

Concepções de adultos com deficiência acerca das condições de trabalho no contexto de pandemia da COVID-19

The objective of this study is to analyze the adults reports with disabilities about the work routine lived in the context of the COVID-19 pandemic and describe the work dynamics. This is a qualitative research, with an interpretive and descriptive-exploratory approach. 11 adults with disabilities participated, inserted in the job market. For data collection, it was used a semi-structured interview script. The interviews took place through the Google Meet platform and were recorded, transcribed and revisited by the researchers. The analysis of information were based on content analysis. As results, it was found that the work routine during a pandemic was mostly based on remote work, removal, dismissal, reduction and/or flexibility in working hours, as well as changing the employment relationship. The positive aspects considered during the pandemic in relation to work were flexibility of time, dedication to other tasks, autonomy and independence. As negative aspects it were pointed out digital platforms, communication difficulties, fear of being fired, increase or decrease in service demand and lack of social interaction. It is concluded that there are issues that cross excluding actions, targeting people with disabilities. On the other hand, some reported situations, such as unemployment, represent a reality faced by many Brazilian workers with and without disabilities in the context of the COVID-19 pandemic, which reflect the capitalist logic in the labor marketEl estudio tuvo como objetivo analizar los relatos de adultos con discapacidad sobre la rutina laboral vivida durante la pandemia de la COVID-19, así como describir posibles cambios en la dinámica de trabajo y concepciones de los entrevistados en los contextos descritos. Se trata de una investigación cualitativa, con enfoque interpretativo y descriptivo-exploratorio. Participaron once adultos con discapacidad, del mercado laboral. Para la recopilación de datos se utilizó un guión de entrevista semiestructurado. Las entrevistas se realizaron a través de la plataforma Google Meet y fueron grabadas, transcritas y revisadas por las investigadoras.. El análisis de las informaciones se basaron en el análisis del contenido. Los resultados mostraron que la rutina laboral durante la pandemia fue mayoritariamente basada en el trabajo a distancia, bajas, reducción y / o flexibilización de la jornada laboral, así como cambios en el contrato de trabajo. Los aspectos positivos considerados durante la pandemia en relación al trabajo fueron la flexibilidad del tiempo, dedicación a otras tareas, autonomía e independencia. Como aspectos negativos fueron apuntados las plataformas digitales, dificultad de comunicación, miedo al despido, el aumento o disminución de la demanda de servicios y la falta de interacción social. Se concluye que hay cuestiones que pasan por acciones excluyentes, teniendo como objetivo las personas con discapacidad.  Por otro lado, algunas situaciones informadas, como el desempleo, representan una realidad enfrentada por la mayoría de los trabajadores brasileños con y sin discapacidad, en el contexto de la pandemia de la COVID-19, que reflejan la lógica capitalista en el mercado laboralO objetivo deste estudo é analisar o relato de adultos com deficiência acerca da rotina trabalhista vivida no contexto de pandemia da COVID-19 e descrever a dinâmica de trabalho. Trata-se de uma pesquisa de cunho qualitativo, com enfoque interpretativista e descritivo-exploratório. Participaram 11 adultos com deficiência, inseridos no mercado de trabalho. Para a coleta de dados, utilizou-se um roteiro semiestruturado de entrevista. As entrevistas ocorreram via utilização do aplicativo Google Meet e foram gravadas, transcritas e revisitadas pelas pesquisadoras. As análises das informações tiveram por base a análise de conteúdo. Como resultados, verificou-se que a rotina trabalhista durante a pandemia foi majoritariamente baseada no trabalho remoto, afastamento, demissão, redução e/ou flexibilização do horário de serviço, bem como mudança do vínculo empregatício. Os aspectos positivos considerados durante a pandemia em relação ao trabalho foram a flexibilização de tempo, dedicação a outras tarefas, autonomia e independência. Como aspectos negativos foram apontados plataformas digitais, dificuldade de comunicação, medo de demissão, aumento ou diminuição da demanda de serviço e a falta de interação social. Conclui-se que há questões que atravessam ações excludentes, tendo como alvo as pessoas com deficiência. Por outro lado, algumas situações relatadas, como o desemprego, representam uma realidade enfrentada por muitos trabalhadores brasileiros com e sem deficiência no contexto da pandemia da COVID-19, que refletem a lógica capitalista no mercado de trabalho

Antioxidant adjustments of olive trees (Olea europaea) under field stress conditions

Extreme climate events are increasingly frequent, and the 2017 summer was particularly critical in the Mediterranean region. Olive is one of the most important species of this region, and these climatic events represent a threat to this culture. However, it remains unclear how olive trees adjust the antioxidant enzymatic system and modulate the metabolite profile under field stress con-ditions. Leaves from two distinct adjacent areas of an olive orchard, one dry and the other hydrated, were harvested. Tree water status, oxidative stress, antioxidant enzymes, and phenolic and lipo-philic metabolite profiles were analyzed. The environmental conditions of the 2017 summer caused a water deficit in olive trees of the dry area, and this low leaf water availability was correlated with the reduction of long†chain alkanes and fatty acids. Hydrogen peroxide (H2O2) and superoxide radical (O2•–) levels increased in the trees collected from the dry area, but lipid peroxidation did not augment. The antioxidant response was predominantly marked by guaiacol peroxidase (GPOX) activity that regulates the H2O2 harmful effect and by the action of flavonoids (luteolin†7†O†glucu-ronide) that may act as reactive oxygen species scavengers. Secoiridoids adjustments may also con-tribute to stress regulation. This work highlights for the first time the protective role of some metabolite in olive trees under field drought conditions.Foundation for Science and Technology (FCT, Portugal) and Ministério da Educação e Ciência supported this work through national funds and the co-funding by the FEDER within the PT2020 Partnership Agreement and COMPETE 2010. Within the projects of the CEF research unit UI0183–UID/BIA/04004/2020, QOPNA research unit UID/QUI/00062/2019, LAQV-REQUIMTE UIDB/50006/2020, and CIMO UIDB/00690/2020. FCT supported the doctoral fellowship of MAraújo (SFRH/BD/116801/2016), N. Mariz-Ponte (SFRH/BD/138187/2018), and the research contract of MC Dias (SFRH/BPD/100865/2014) through POCH/FSE.info:eu-repo/semantics/publishedVersio