Compact Wideband Microstrip Patch Antenna Design for Breast Cancer Detection

The current breast cancer detection techniques are mostly invasive and suffer from high cost, high false rate and inefficacy in early detection. These limitations can be subdued by development of non-invasive microwave detection system whose performance is predominantly dependent on the antenna used in the system. The designing of a compact wideband antenna and matching its impedance with breast phantom is a challenging task. In this paper, we have designed a compact antenna matched with the breast phantom operating in wideband frequency from 1 to 6 GHz capable to detect the dielectric (or impedance) contrast of the benign and malignant tissue. The impedance of the antenna is matched to a cubically shaped breast phantom and a very small tumor (volume=1 cm3). The antenna is tuned to the possible range of electrical properties of breast phantom and tumour (permittivity ranging from 10 to 20 and conductivity from 1.5 to 2.5 S/m). The return loss (S11), E-field distribution and specific absorption rate (SAR) are simulated. The operating band of antenna placed near the phantom without tumor was found to be (1.11-5.47)GHz and with tumor inside phantom is (1.29-5.50)GHz. Results also show that the SAR of the antenna is within the safety limit

Development of Micro-Emulsion Gel Based Topical Delivery of Salicylic Acid and Neem Oil for the Management of Psoriasis

Microemulsions (MEs) are clear, thermodynamically stable systems. They were used to solubilise drugs and to improve topical drug availability. Salicylic acid (SA) is a keratolytic agent used in topical products with antimicrobial actions. This study aimed to formulate an optimized SA micro emulsion gel for the slow, variable and incomplete oral drug absorption in patient suffering from psoriasis infection. The dispersion solubility of SA was studied in various oils, surfactants and co-surfactants and by constructing pseudo phase ternary diagram, micro emulsion area was identified. The optimized formulations of micro emulsion were subjected to thermodynamic stability tests. After stability study, stable formulation was characterized for droplet size, pH determination, centrifugation, % drug content in micro emulsion, zeta Potential and vesicle size measurement and then micro emulsion gel were prepared and characterized for spreadability, measurement of viscosity, drug content, In-vitro diffusion, in-vitro release data. Labrasol was selected as surfactant, plurol oleique as co surfactant and neem oil as oil component based on solubility study. The optimized formulation contained SA 0.05 (%w/w), labrasol (24%), plurol oleique (8 %) and neem oil (8%). The in vitro drug release from SA micro emulsion gel was found to be considerably higher in comparison to that of the pure drug. The in-vitro diffusion of micro emulsion gel was significantly good. Based on this study, it can be concluded the solubility and permeability of SA can be increased by formulating into micro emulsion gel. Keywords: Salicylic Acid, Neem Oil, Micro-emulsion, In-vitro diffusion, Zeta potential, Stability, Labraso

Formulation Development and Evaluation of Lansoprazole Mucoadhesive Microsphere

Lansoprazole belongs to a class of antisecretory compounds, the substituted benzimidazoles, that do not exhibit anticholinergic or histamine H2-receptor antagonist properties, but rather suppress gastric acid secretion by specific inhibition of the (H+,K+)-ATPase enzyme system at the secretary surface of the gastric parietal cell. Because this enzyme system is regarded as the acid (proton) pump within the parietal cell, lansoprazole has been characterized as a gastric acid-pump inhibitor, in that it blocks the final step of acid production. This effect is dose-related and leads to inhibition of both basal and stimulated gastric acid secretion irrespective of the stimulus. The aim of the present study was to develop lansoprazole loaded thiolated chitosan microspheres were prepared by emulsifying method using liquid paraffin light and heavy in ratio of 50:50 as a dispersing medium and glutaraldehyde used as a cross-linking agent. The prepared microspheres were evaluated for mean particle size and particle size distribution, drug content, mucoadhesion measurement and in-vitro drug release. FT-IR spectroscopic analysis was performed to ascertain drug polymer interaction. The release profiles showed first order release behavior up to 12 hours where the highest drug release was 88.89 % of the lansoprazole loaded in the thiolated chitosan microspheres, indicating a strong crosslinking between chitosan and glutaraldehyde. From the results of the present investigation it may be concluded that drug loaded chitosan microspheres can be prepared by a simple technique which avoids the use of complex apparatus and special precautions. Keywords: Lansoprazole, Thiolated chitosan, Microspheres, Glutaraldehyde, Mucoadhesion measuremen

A novel approach for optimal weight factor of DT-CWT coefficients for land cover classification using MODIS data.

International audiencePresently, there is a need to explore the possibility to maximize the use of MODIS (Moderate Resolution Imaging Spectroradiometer) data as it has very good spectral (36 bands) and temporal resolution whereas its spatial resolution is moderate i.e. 250m, 500m, and 1km. Because of its moderate spatial resolution, its application for land cover classification is limited. Therefore, in this paper, an attempt has been made to enhance its spatial resolution and utilize the information contained in the different bands together to achieve good land cover classification accuracy, so that, in future, MODIS data can be used more effectively. For resolution enhancement, modified dual tree complex wavelet transform (DT-CWT) has been employed, where DT-CWT has been modified by critically analyzing the effect of weight factor of the DT-CWT coefficients on land cover classification. For this purpose, image statistics parameter like Mean of the image has also been considered. The proposed technique has been applied on the six bands of MODIS data which have spatial resolution of 500m. It is observed that weight factor of the high-frequency sub-bands is quite sensitive for computation of classification accuracy. Index Terms— DT-CWT, Resolution enhancement, wavelets, weights, MODIS 1.INTRODUCTION Satellite images are being used in various applications such as geoscience studies, astronomy and geographical information systems where their resolution plays a critical role but on the other hand, directly obtaining a high resolution data is an another herculean task because of high cost of sensor. Land cover classification from satellite data is a central topic in satellite imaging applications. Therefore, it becomes a necessity to develop and utilize a reliable resolution enhancement technique to obtain accurate information as much as possible as per application from the freely available moderate resolution satellite data. In this regard, many image resolution enhancement techniques have been developed which are interpolations (nearest neighbor, bilinear and bicubic) and wavelets (DWT, SWT, WZP etc.) based. Interpolation techniques [1] have been widely used for resolution enhancement but it results in loss of edges (i.e., high frequency components) of an image. Nowadays, resolution enhancement is being carried out in the wavelet domain. There are many wavelet transforms which have acquired the place. Discrete wavelet transform (DWT) [2] has also been widely used in order to preserve the high-frequency components of the image but its disadvantage is that it ends up with some ringing artifacts into the image since it is not found to be shift-invariant because of decimations and suppression of wavelet coefficients exploited by DWT. It basically suffers from four shortcomings i.e., oscillations, shift variance, aliasing and lack of directionality which can lead to some artifacts in the image and difficulties in signal modeling. Hence, the DWT has somewhat disappointed the researchers for satellite images. Therefore, in order to alleviate all these drawbacks of DWT [2,3], a new kind of wavelet was introduced by Kingsbury which is known as DT-CWT (Dual tree complex wavelet transform) [1,3]. It possesses shift-invariant property and has the capability of improving directional resolution (because of good directional sensitivity) as compared to that of the decimated DWT. That's why, DT-CWT has been employed in this paper for resolution enhancement of moderate resolution satellite images. It is foremost to discover the possibility of maximizing the use of freely available satellite data like MODIS. It consists of several bands in which different information is present, but has certain limitations as well like low spatial resolution i.e. 500m which is a major obstacle in obtaining that information accurately. Many researchers have worked on resolution enhancement techniques for visualization enhancement whereas in this paper, main motive is to enhance the land cover classification accuracy which is not reported much for satellite images like MODIS yet. Variance minimization [4] has also been explored by several researchers for weights optimization but it is somewhat 4528 978-1-5090-3332-4/16/$31.0

Convergence of an Iteration of Fifth-Order Using Weaker Conditions on First Order Fréchet Derivative in Banach Spaces

[EN] The convergence analysis both local under weaker Argyros-type conditions and semilocal under. omega-condition is established using first order Frechet derivative for an iteration of fifth order in Banach spaces. This avoids derivatives of higher orders which are either difficult to compute or do not exist at times. The Lipchitz and the Holder conditions are particular cases of the omega-condition. Examples can be constructed for which the Lipchitz and Holder conditions fail but the omega-condition holds. Recurrence relations are used for the semilocal convergence analysis. Existence and uniqueness theorems and the error bounds for the solution are provided. Different examples are solved and convergence balls for each of them are obtained. These examples include Hammerstein-type integrals to demonstrate the applicability of our approach.Singh, S.; Gupta, D.; Singh, R.; Singh, M.; Martínez Molada, E. (2018). Convergence of an Iteration of Fifth-Order Using Weaker Conditions on First Order Fréchet Derivative in Banach Spaces. International Journal of Computational Methods. 15(6):1-18. https://doi.org/10.1142/S0219876218500482S11815

A numerical study of magnetohydrodynamic transport of nanofluids from a vertical stretching sheet with exponential temperature-dependent viscosity and buoyancy effects

In this paper, a mathematical study is conducted of steady incompressible flow of a temperature-dependent viscous nanofluid from a vertical stretching sheet under applied external magnetic field and gravitational body force effects. The Reynolds exponential viscosity model is deployed. Electrically-conducting nanofluids are considered which comprise a suspension of uniform dimension nanoparticles suspended in viscous base fluid. The nanofluid sheet is extended with a linear velocity in the axial direction. The Buonjiornio model is utilized which features Brownian motion and thermophoresis effects. The partial differential equations for mass, momentum, energy and species (nano-particle concentration) are formulated with magnetic body force term. Viscous and Joule dissipation effects are neglected. The emerging nonlinear, coupled, boundary value problem is solved numerically using the Runge–Kutta fourth order method along with a shooting technique. Graphical solutions for velocity, temperature, concentration field, skin friction and Nusselt number are presented. Furthermore stream function plots are also included. Validation with Nakamura’s finite difference algorithm is included. Increasing nanofluid viscosity is observed to enhance temperatures and concentrations but to reduce velocity magnitudes. Nusselt number is enhanced with both thermal and species Grashof numbers whereas it is reduced with increasing thermophoresis parameter and Schmidt number. The model is applicable in nano-material manufacturing processes involving extruding sheets