The Discovery of Six Recycled Pulsars from the Arecibo 327-MHz Drift-Scan Pulsar Survey

Recycled pulsars are old ($\gtrsim10^{8}$ yr) neutron stars that are descendants from close, interacting stellar systems. In order to understand their evolution and population, we must find and study the largest number possible of recycled pulsars in a way that is as unbiased as possible. In this work, we present the discovery and timing solutions of five recycled pulsars in binary systems (PSRs J0509$+$0856, J0709$+$0458, J0732$+$2314, J0824$+$0028, J2204$+$2700) and one isolated millisecond pulsar (PSR J0154$+$1833). These were found in data from the Arecibo 327-MHz Drift-Scan Pulsar Survey (AO327). All these pulsars have a low dispersion measure (DM) ($\lesssim 45 \, \rm{pc}\, cm^{-3}$), and have a DM-determined distance of $\lesssim$ 3 kpc. Their timing solutions, have data spans ranging from 1 to $\sim$ 7 years, include precise estimates of their spin and astrometric parameters, and for the binaries, precise estimates of their Keplerian binary parameters. Their orbital periods range from about 4 to 815 days and the minimum companion masses (assuming a pulsar mass of 1.4 $\rm{M_{\odot}}$) range from $\sim$ 0.06--1.11 $\rm{M_{\odot}}$. For two of the binaries we detect post-Keplerian parameters; in the case of PSR~J0709$+$0458 we measure the component masses but with a low precision, in the not too distant future the measurement of the rate of advance of periastron and the Shapiro delay will allow very precise mass measurements for this system. Like several other systems found in the AO327 data, PSRs J0509$+$0854, J0709$+$0458 and J0732$+$2314 are now part of the NANOGrav timing array for gravitational wave detection

Three Millisecond Pulsars in FERMI LAT Unassociated Bright Sources

We searched for radio pulsars in 25 of the non-variable, unassociated sources in the Fermi LAT Bright Source List with the Green Bank Telescope at 820 MHz. We report the discovery of three radio and gamma-ray millisecond pulsars (MSPs) from a high Galactic latitude subset of these sources. All of the pulsars are in binary systems, which would have made them virtually impossible to detect in blind gamma-ray pulsation searches. They seem to be relatively normal, nearby (<=2 kpc) millisecond pulsars. These observations, in combination with the Fermi detection of gamma-rays from other known radio MSPs, imply that most, if not all, radio MSPs are efficient gamma-ray producers. The gamma-ray spectra of the pulsars are power-law in nature with exponential cutoffs at a few GeV, as has been found with most other pulsars. The MSPs have all been detected as X-ray point sources. Their soft X-ray luminosities of ~10^{30-31} erg/s are typical of the rare radio MSPs seen in X-rays.Comment: Accepted for publication in ApJ Letter

Placing limits on the stochastic gravitational-wave background using European Pulsar Timing Array data

Direct detection of low-frequency gravitational waves ($10^{-9} - 10^{-8}$ Hz) is the main goal of pulsar timing array (PTA) projects. One of the main targets for the PTAs is to measure the stochastic background of gravitational waves (GWB) whose characteristic strain is expected to approximately follow a power-law of the form $h_c(f)=A (f/\hbox{yr}^{-1})^{\alpha}$, where $f$ is the gravitational-wave frequency. In this paper we use the current data from the European PTA to determine an upper limit on the GWB amplitude $A$ as a function of the unknown spectral slope $\alpha$ with a Bayesian algorithm, by modelling the GWB as a random Gaussian process. For the case $\alpha=-2/3$, which is expected if the GWB is produced by supermassive black-hole binaries, we obtain a 95% confidence upper limit on $A$ of $6\times 10^{-15}$, which is 1.8 times lower than the 95% confidence GWB limit obtained by the Parkes PTA in 2006. Our approach to the data analysis incorporates the multi-telescope nature of the European PTA and thus can serve as a useful template for future intercontinental PTA collaborations.Comment: 14 pages, 8 figures, 3 tables, mnras accepte

Detection of Bursts from FRB 121102 with the Effelsberg 100-m Radio Telescope at 5 GHz and the Role of Scintillation

FRB 121102, the only repeating fast radio burst (FRB) known to date, was discovered at 1.4 GHz and shortly after the discovery of its repeating nature, detected up to 2.4 GHz. Here we present three bursts detected with the 100-m Effelsberg radio telescope at 4.85 GHz. All three bursts exhibited frequency structure on broad and narrow frequency scales. Using an autocorrelation function analysis, we measured a characteristic bandwidth of the small-scale structure of 6.4$\pm$1.6 MHz, which is consistent with the diffractive scintillation bandwidth for this line of sight through the Galactic interstellar medium (ISM) predicted by the NE2001 model. These were the only detections in a campaign totaling 22 hours in 10 observing epochs spanning five months. The observed burst detection rate within this observation was inconsistent with a Poisson process with a constant average occurrence rate; three bursts arrived in the final 0.3 hr of a 2 hr observation on 2016 August 20. We therefore observed a change in the rate of detectable bursts during this observation, and we argue that boosting by diffractive interstellar scintillations may have played a role in the detectability. Understanding whether changes in the detection rate of bursts from FRB 121102 observed at other radio frequencies and epochs are also a product of propagation effects, such as scintillation boosting by the Galactic ISM or plasma lensing in the host galaxy, or an intrinsic property of the burst emission will require further observations.Comment: Accepted to ApJ. Minor typos correcte

The PALFA Survey: Going to great depths to find radio pulsars

The on-going PALFA survey is searching the Galactic plane (|b| < 5 deg., 32 < l < 77 deg. and 168 < l < 214 deg.) for radio pulsars at 1.4 GHz using ALFA, the 7-beam receiver installed at the Arecibo Observatory. By the end of August 2012, the PALFA survey has discovered 100 pulsars, including 17 millisecond pulsars (P < 30 ms). Many of these discoveries are among the pulsars with the largest DM/P ratios, proving that the PALFA survey is capable of probing the Galactic plane for millisecond pulsars to a much greater depth than any previous survey. This is due to the survey's high sensitivity, relatively high observing frequency, and its high time and frequency resolution. Recently the rate of discoveries has increased, due to a new more sensitive spectrometer, two updated complementary search pipelines, the development of online collaborative tools, and access to new computing resources. Looking forward, focus has shifted to the application of artificial intelligence systems to identify pulsar-like candidates, and the development of an improved full-resolution pipeline incorporating more sophisticated radio interference rejection. The new pipeline will be used in a complete second analysis of data already taken, and will be applied to future survey observations. An overview of recent developments, and highlights of exciting discoveries will be presented.Comment: Proceedings of IAUS 291 "Neutron Stars and Pulsars: Challenges and Opportunities after 80 years", J. van Leeuwen (ed.); 6 pages, 4 figure

The noise properties of 42 millisecond pulsars from the European Pulsar Timing Array and their impact on gravitational wave searches

The sensitivity of Pulsar Timing Arrays to gravitational waves depends on the noise present in the individual pulsar timing data. Noise may be either intrinsic or extrinsic to the pulsar. Intrinsic sources of noise will include rotational instabilities, for example. Extrinsic sources of noise include contributions from physical processes which are not sufficiently well modelled, for example, dispersion and scattering effects, analysis errors and instrumental instabilities. We present the results from a noise analysis for 42 millisecond pulsars (MSPs) observed with the European Pulsar Timing Array. For characterising the low-frequency, stochastic and achromatic noise component, or "timing noise", we employ two methods, based on Bayesian and frequentist statistics. For 25 MSPs, we achieve statistically significant measurements of their timing noise parameters and find that the two methods give consistent results. For the remaining 17 MSPs, we place upper limits on the timing noise amplitude at the 95% confidence level. We additionally place an upper limit on the contribution to the pulsar noise budget from errors in the reference terrestrial time standards (below 1%), and we find evidence for a noise component which is present only in the data of one of the four used telescopes. Finally, we estimate that the timing noise of individual pulsars reduces the sensitivity of this data set to an isotropic, stochastic GW background by a factor of >9.1 and by a factor of >2.3 for continuous GWs from resolvable, inspiralling supermassive black-hole binaries with circular orbits.Comment: Accepted for publication by the Monthly Notices of the Royal Astronomical Societ

Pulsar Timing and its Application for Navigation and Gravitational Wave Detection

Pulsars are natural cosmic clocks. On long timescales they rival the precision of terrestrial atomic clocks. Using a technique called pulsar timing, the exact measurement of pulse arrival times allows a number of applications, ranging from testing theories of gravity to detecting gravitational waves. Also an external reference system suitable for autonomous space navigation can be defined by pulsars, using them as natural navigation beacons, not unlike the use of GPS satellites for navigation on Earth. By comparing pulse arrival times measured on-board a spacecraft with predicted pulse arrivals at a reference location (e.g. the solar system barycenter), the spacecraft position can be determined autonomously and with high accuracy everywhere in the solar system and beyond. We describe the unique properties of pulsars that suggest that such a navigation system will certainly have its application in future astronautics. We also describe the on-going experiments to use the clock-like nature of pulsars to "construct" a galactic-sized gravitational wave detector for low-frequency (f_GW ~1E-9 - 1E-7 Hz) gravitational waves. We present the current status and provide an outlook for the future.Comment: 30 pages, 9 figures. To appear in Vol 63: High Performance Clocks, Springer Space Science Review

B Cells Regulate Neutrophilia during Mycobacterium tuberculosis Infection and BCG Vaccination by Modulating the Interleukin-17 Response

We have previously demonstrated that B cells can shape the immune response to Mycobacterium tuberculosis, including the level of neutrophil infiltration and granulomatous inflammation at the site of infection. The present study examined the mechanisms by which B cells regulate the host neutrophilic response upon exposure to mycobacteria and how neutrophilia may influence vaccine efficacy. To address these questions, a murine aerosol infection tuberculosis (TB) model and an intradermal (ID) ear BCG immunization mouse model, involving both the μMT strain and B cell-depleted C57BL/6 mice, were used. IL (interleukin)-17 neutralization and neutrophil depletion experiments using these systems provide evidence that B cells can regulate neutrophilia by modulating the IL-17 response during M. tuberculosis infection and BCG immunization. Exuberant neutrophilia at the site of immunization in B cell-deficient mice adversely affects dendritic cell (DC) migration to the draining lymph nodes and attenuates the development of the vaccine-induced Th1 response. The results suggest that B cells are required for the development of optimal protective anti-TB immunity upon BCG vaccination by regulating the IL-17/neutrophilic response. Administration of sera derived from M. tuberculosis-infected C57BL/6 wild-type mice reverses the lung neutrophilia phenotype in tuberculous μMT mice. Together, these observations provide insight into the mechanisms by which B cells and humoral immunity modulate vaccine-induced Th1 response and regulate neutrophila during M. tuberculosis infection and BCG immunization. © 2013 Kozakiewicz et al

Tuberculosis immunopathology: the neglected role of extracellular matrix destruction

The extracellular matrix in the lung must be destroyed for Mycobacterium tuberculosis—the agent that causes tuberculosis (TB)—to spread. The current paradigm proposes that this destruction occurs as a result of the action of proinflammatory cytokines, chemokines, immune cells, and lipids that mediate TB-associated necrosis in the lung. However, this view neglects the fact that lung matrix can only be degraded by proteases. We propose an original conceptual framework of TB immunopathology that may lead directly to treatments that involve inhibition of matrix metalloproteinase activity to hinder matrix destruction and reduce the morbidity and mortality associated with T

Discovery of Pulsed γ\gamma-rays from PSR J0034-0534 with the Fermi LAT: A Case for Co-located Radio and γ\gamma-ray Emission Regions

Millisecond pulsars (MSPs) have been firmly established as a class of gamma-ray emitters via the detection of pulsations above 0.1 GeV from eight MSPs by the Fermi Large Area Telescope (LAT). Using thirteen months of LAT data significant gamma-ray pulsations at the radio period have been detected from the MSP PSR J0034-0534, making it the ninth clear MSP detection by the LAT. The gamma-ray light curve shows two peaks separated by 0.274$\pm$0.015 in phase which are very nearly aligned with the radio peaks, a phenomenon seen only in the Crab pulsar until now. The $\geq$0.1 GeV spectrum of this pulsar is well fit by an exponentially cutoff power law with a cutoff energy of 1.8$\pm 0.6\pm$0.1 GeV and a photon index of 1.5$\pm 0.2\pm$0.1, first errors are statistical and second are systematic. The near-alignment of the radio and gamma-ray peaks strongly suggests that the radio and gamma-ray emission regions are co-located and both are the result of caustic formation.Comment: 20 pages, 3 figures, 2 tables. Accepted for publication in Ap