Achievement of the planetary defense investigations of the Double Asteroid Redirection Test (DART) mission

NASA's Double Asteroid Redirection Test (DART) mission was the first to demonstrate asteroid deflection, and the mission's Level 1 requirements guided its planetary defense investigations. Here, we summarize DART's achievement of those requirements. On 2022 September 26, the DART spacecraft impacted Dimorphos, the secondary member of the Didymos near-Earth asteroid binary system, demonstrating an autonomously navigated kinetic impact into an asteroid with limited prior knowledge for planetary defense. Months of subsequent Earth-based observations showed that the binary orbital period was changed by –33.24 minutes, with two independent analysis methods each reporting a 1σ uncertainty of 1.4 s. Dynamical models determined that the momentum enhancement factor, β, resulting from DART's kinetic impact test is between 2.4 and 4.9, depending on the mass of Dimorphos, which remains the largest source of uncertainty. Over five dozen telescopes across the globe and in space, along with the Light Italian CubeSat for Imaging of Asteroids, have contributed to DART's investigations. These combined investigations have addressed topics related to the ejecta, dynamics, impact event, and properties of both asteroids in the binary system. A year following DART's successful impact into Dimorphos, the mission has achieved its planetary defense requirements, although work to further understand DART's kinetic impact test and the Didymos system will continue. In particular, ESA's Hera mission is planned to perform extensive measurements in 2027 during its rendezvous with the Didymos–Dimorphos system, building on DART to advance our knowledge and continue the ongoing international collaboration for planetary defense

Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

publisher: Elsevier articletitle: Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes journaltitle: Cell articlelink: https://doi.org/10.1016/j.cell.2018.05.046 content_type: article copyright: © 2018 Elsevier Inc

Medical pharmacology and therapeutics, 3rd ed./ Waller

vi, 734 hal.: ill, tab.; 27 cm

Medical pharmacology and Therapeutics: Dedication

To our families. Medical Pharmacology & Therapeutics, now in its fifth edition, offers medical students all they need to know to become safe and effective prescribers. It forms a complete, integrated resource for basic pharmaceutical science, pathophysiology, clinical pharmacology, and therapeutics

Medical Pharmacology and Therapeutics

This text covers the whole gamut of pharmacology from basic science pharmacology and pathophysiology, through clinical pharmacology to therapeutics. This integrative approach is in line with the medical curricula. The first section covers the basic principles, followed by the bulk of the book organized by body systems. The book ends with sections on toxicity and prescribing practice. Each chapter ends with case histories, multiple choice questions and a tabular presentation of all common drugs within a particular class

Medical Pharmacology and Therapeutics. 2nd edition

This book covers the whole gamut of pharmacology from basic science pharmacology and pathophysiology, through clinical pharmacology to therapeutics. This integrative approach is in line with the new medical curricula. The first section covers the basic principles, followed by the bulk of the book organised by body systems. The book ends with sections on toxicity and prescribing practice. Each chapter ends with case histories, multiple choice questions and a tabular presentation of all common drugs within a particular class.The level of detail closely matches the needs of medical students and the current medical curriculum