BOBCATS

The bobcat (Lynx rufus), alias “wildcat,” is a medium-sized member of the North American cat family. It can be distinguished at a distance by its graceful catlike movements, short “bobbed” tail, and round face and pointed ears. Visible at close distances are black hair at the tip of the tail and prominent white dots on the upper side of the ears. Body hair color varies, but the animal’s sides and flanks are usually brownish black or reddish brown with either distinct or faint black spots. The back is commonly brownish yellow with a dark line down the middle. The chest and outside of the legs are covered with brownish to light gray fur with black spots or bars. Bobcats living at high elevations and in northern states and Canada have relatively long hair. In southern states, bobcats may have a yellowish or reddish cast on their backs and necks. The bobcat occurs in a wide variety of habitats from the Atlantic to the Pacific Ocean and from Mexico to northern British Columbia. It occurs in the 48 contiguous states. The bobcat is as adapted to subtropical forests as it is to dense shrub and hardwood cover in temperate climates. Other habitats include chaparral, wooded streams, river bottoms, canyonlands, and coniferous forests. Bobcats prefer areas where these native habitat types are interspersed with agriculture and escape cover (rocky outcrops) close by. The bobcat has thrived where agriculture is interspersed through the above native habitat types, as in southern Canada. Bobcats are capable of hunting and killing prey that range from the size of a mouse to that of a deer. Rabbits, tree squirrels, ground squirrels, woodrats, porcupines, pocket gophers, and ground hogs comprise most of their diet. Opossums, raccoon, grouse, wild turkey, and other ground-nesting birds are also eaten. Occasionally, insects and reptiles can be part of the bobcat’s diet. Bobcats are secretive, shy, solitary, and seldom seen in the wild. They are active during the day but prefer twilight, dawn, or night hours. Bobcats tend to travel well-worn animal trails,logging roads, and other paths. They use their acute vision and hearing for locating enemies and prey

Salivary Defense Proteins: Their Network and Role in Innate and Acquired Oral Immunity

There are numerous defense proteins present in the saliva. Although some of these molecules are present in rather low concentrations, their effects are additive and/or synergistic, resulting in an efficient molecular defense network of the oral cavity. Moreover, local concentrations of these proteins near the mucosal surfaces (mucosal transudate), periodontal sulcus (gingival crevicular fluid) and oral wounds and ulcers (transudate) may be much greater, and in many cases reinforced by immune and/or inflammatory reactions of the oral mucosa. Some defense proteins, like salivary immunoglobulins and salivary chaperokine HSP70/HSPAs (70 kDa heat shock proteins), are involved in both innate and acquired immunity. Cationic peptides and other defense proteins like lysozyme, bactericidal/permeability increasing protein (BPI), BPI-like proteins, PLUNC (palate lung and nasal epithelial clone) proteins, salivary amylase, cystatins, prolin-rich proteins, mucins, peroxidases, statherin and others are primarily responsible for innate immunity. In this paper, this complex system and function of the salivary defense proteins will be reviewed

Mendelian randomization of circulating polyunsaturated fatty acids and colorectal cancer risk

Background: Results from epidemiologic studies examining polyunsaturated fatty acids (PUFA) and colorectal cancer risk are inconsistent. Mendelian randomization may strengthen causal inference from observational studies. Given their shared metabolic pathway, examining the combined effects of aspirin/NSAID use with PUFAs could help elucidate an association between PUFAs and colorectal cancer risk. Methods: Information was leveraged from genome-wide association studies (GWAS) regarding PUFA-associated SNPs to create weighted genetic scores (wGS) representing genetically predicted circulating blood PUFAs for 11,016 non-Hispanic white colorectal cancer cases and 13,732 controls in the Genetics and Epidemiology of Colorectal Cancer Consortium (GECCO). Associations per SD increase in the wGS were estimated using unconditional logistic regression. Interactions between PUFA wGSs and aspirin/NSAID use on colorectal cancer risk were also examined. Results: Modest colorectal cancer risk reductions were observed per SD increase in circulating linoleic acid [ORLA = 0.96; 95% confidence interval (CI) = 0.93-0.98; P = 5.2 × 10-4] and α-linolenic acid (ORALA = 0.95; 95% CI = 0.92-0.97; P = 5.4 × 10-5), whereas modest increased risks were observed for arachidonic (ORAA = 1.06; 95% CI = 1.03-1.08; P = 3.3 × 10-5), eicosapentaenoic (OREPA = 1.04; 95% CI = 1.01-1.07; P = 2.5 × 10-3), and docosapentaenoic acids (ORDPA = 1.03; 95% CI = 1.01-1.06; P = 1.2 × 10-2). Each of these effects was stronger among aspirin/NSAID nonusers in the stratified analyses. Conclusions: Our study suggests that higher circulating shorter-chain PUFAs (i.e., LA and ALA) were associated with reduced colorectal cancer risk, whereas longer-chain PUFAs (i.e., AA, EPA, and DPA) were associated with an increased colorectal cancer risk. Impact: The interaction of PUFAs with aspirin/NSAID use indicates a shared colorectal cancer inflammatory pathway. Future research should continue to improve PUFA genetic instruments to elucidate the independent effects of PUFAs on colorectal cancer

TEACHING YOUTH WILDLIFE DAMAGE MANAGEMENT PRINCIPLES COMPARING TECHNIQUES (HOW TO’S AND HELPFUL HINTS)

Youth need to receive research-based information about wildlife damage management principles and techniques so they can make wise decisions regarding issues. Educators also need to identify the best techniques for specific ages. We presented wildlife damage management topics on 70 separate occasions to over 4,500 youth in Nebraska’s Panhandle from 1993 through 1996. Youth, ages 7 through 10 year old, comprised the majority of the audience. Presentations included a furbearer pelt display and illustration of fur preparation, wildlife population influences using interactive games and demonstrations, wildlife damage principles using lecture, video, small group discussion and demonstration, and historical changes in furtaking and habitat using drama. Drama and character portrayal were noticeably more effective for grades K through five. Demonstration and laboratory techniques were most effective for grades 6 through 9. Video and directed small group discussion were effective through high school, but high school youth favored demonstrations and displays over video, small group discussion and worksheets. Lecture and worksheet were used sparingly and only for high school youth

[Teenagers Dancing in Exline Park]

Photograph of teenagers dancing in Exline Park. In the photograph, teenagers dance in pairs while others sit in folding chairs on the left side