539 research outputs found

    Cuerpo común y guerra de los afectos. Coreografías globales y cuerpos en serie del Afectocapital

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    El ensayo propone un marco de análisis de las nuevas formas de operación del poder como dispositivos de producción afectiva y su operación a través del paradigma del pancoreográfico, o conjunto de dispositivos de distribución global de coreografías estándar. Plantea una redefinición de la corporalidad como campo de fuerzas relacionales en movimiento y la posibilidad de desarrollar resistencias a los mecanismos de estandarización de cuerpos del afectocapital, a través de nuevas tecnologías del movimiento a través del paradigma del cuerpo pos-anatómico.This essay proposes a frame of analysis of the new forms of power operating, as the devices of affective production trhough the paradygm of panchoreographics, or the sum of all the devices of global distribution of standard choreographies. It proposes a redefinition of corporality as a field of related sthrenghts in movement, and the possibility of the standarisation of the bodies in the affection capital, through the new technologies of movement of the paradigm of a post- anatomical body.Cet essai propose un plan de analyse des nouvelles formes d’opération du pouvoir en tant que dispositifs de production affective à travers du paradigme panchoréographique, le conjoint des dispositifs de distribution globalle de choréographies standard. Il presente une redefinition de la corporéité en tant que champ des forces de relation en mouvement, et la possibilité de dévélopper des ressistances aux méchanismes de standarisation des corps du affect-capital, à travers les nouvelles technologies du movement du paradygme du corps post-anatomique

    Undoing Anatomy: Resisting Global Choreographies in the Capitalism of Affects

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    Underlying the imaginaries staged and projected in texts, theater pieces, video, cinema and publicity there are certain anatomic constructions of the senses that are the conditions of possibility for those imaginaries. Such sensory anatomies underlie implicit power mechanisms in late cap­italist societies, which operate at the level of the production of affect and desire of consumers as well as of the concealment of global violence through which the economic system operates. I will propose a frame­work of analysis of such power operations through the analysis of move­ment, and more precisely of what I will call the panchoreographic: a set of technological devices of global distribution that disseminate discrete, standard choreographies in bodies, thus contributing to the production and dissemination of standard affects. Finally, I will show some exam­ples of the work developed by REVERSO in recent years that aims at the radical redefinition of the sensory anatomies that underlie media culture and information society, aiming at the production of a post-anatomical relational body

    Análisis de indicadores para el fomento de la Cultura Científica: una década de actividad en el CSIC

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    Activities to promote Scientific Culture have become common practice in research institutes, which allocate financial and human resources to them. Scientific and technical staff increasingly incorporate this mission into their traditional research and teaching tasks. However, while research and teaching have established indicators, Scientific Culture activities are still considered unusual and are rarely recognized at an institutional level. In this sense, we believe that developing indicators for Scientific Culture would help change this situation and obtain objective data that could be used to orient social communication actions in science. The Consejo Superior de Investigaciones Científicas (CSIC), through its Deputy Vice Presidency of Scientific Culture, has proposed an analysis of the activities developed that help define appropriate Scientific Culture indicators. The CSIC has classified the Scientific Culture activity undertaken between 2011 and 2019, using the following indicators: 1) financial investment; (2) staff dedicated to Scientific Culture; (3) the number and type of activities held; and (4) the public reached. Among the main conclusions, we can highlight that the CSIC has a fairly stable critical mass of about 200 people who are dedicated to Scientific Culture endeavours. Every year around 15,000 activities are carried out (in-person and virtual) with the participation of around 3,000 CSIC workers. Each year more than a million and a half people attended in-person activities. 2020 will be the subject of an individualized study, as the special circumstances of the COVID-19 pandemic have made it a unique exercise with its own analysis identity.Las actividades de fomento de la cultura científica se han convertido en una práctica habitual de las instituciones de investigación, que destinan presupuesto y recursos humanos a este objetivo. Cada vez más personal científico y técnico incorpora esta misión a sus tradicionales tareas de investigación y formación. Sin embargo, mientras la investigación y la docencia cuentan con indicadores establecidos, las actividades de divulgación siguen estando consideradas como un ejercicio extraordinario, pocas veces reconocido institucionalmente. En este sentido, el uso de unos indicadores de cultura científica contribuiría a favorecer un cambio de mentalidad y a la obtención de datos objetivos sobre los que orientar las acciones de comunicación social de la ciencia. En este contexto, el Consejo Superior de Investigaciones Científicas (CSIC), a través de su Vicepresidencia Adjunta de Cultura Científica, se ha propuesto analizar las actividades desarrolladas en esta línea, entre 2011 y 2019, en relación a los siguientes indicadores: 1) la inversión económica; 2) el personal dedicado a cultura científica; 3) el número y tipo de actividades; y 4) el público al que se llega. Entre las principales conclusiones, destaca que el CSIC cuenta con una masa crítica más o menos estable de unas 200 personas que se dedican a tareas de cultura científica. Cada año se realizan alrededor de 15.000 actividades (presenciales y no presenciales) en las que se implican alrededor de 3.000 trabajadoras y trabajadores del CSIC. Cada año participan cerca de un millón y medio de personas de manera presencial

    Características del líquido sinovial en pacientes con artritis idiopática juvenil

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    Introducción: El análisis del líquido sinovial (LS) es una herramienta importante en el diagnóstico de pacientes con artritis idiopática juvenil (AIJ). Pacientes y métodos: Análisis retrospectivo de las características citológicas del LS obtenido de pacientes con AIJ en el periodo 2008-2016. Resultados: Se analizaron 102 LS de 59 pacientes. El 66% fueron mujeres y la forma clínica más frecuente fue la AIJ oligoarticular persistente (52,5%). La mediana de edad al inicio fue de 5 años (RIC 2,4-11,8). El LS generalmente era de características inflamatorias (mediana leucocitos 11.757/mm3; RIC 4.543-18.800) con predominio de polimorfonucleares (PMN, 61%; RIC 30-75). Ocho pacientes (14%) presentaron recuentos inferiores a 2.000 cél/mm3, con predominio de mononucleares (80%), mientras que 3 pacientes (5%) presentaron recuentos superiores a 50.000 cél/mm3, con predominio de PMN (90%). No se encontraron diferencias en los recuentos celulares entre las distintas formas de AIJ. La mediana del recuento de leucocitos de pacientes positivos para ANA fue un 20% inferior a la de niños negativos para ANA (9.340 vs. 11.600/mm3; p = 0,23). La proporción de PMN en LS tendía a aumentar conforme se incrementaba la VSG (p < 0,001) y/o la PCR (p = 0,03). No existe correlación del índice JADAS-10 con el recuento en LS (p = 0,4). El LS en artrocentesis simultáneas de diferentes articulaciones mostró una correlación significativa (p = 0,001). Conclusiones: El LS de pacientes con AIJ generalmente tiene características inflamatorias, aunque un 19% presentó recuentos inferiores a 2.000 o superiores a 50.000 cél/mm3. Los recuentos en pacientes positivos para ANA tendían a ser menores que en los negativos para ANA (no significativo). La proporción de PMN aumentaba con los reactantes.Introduction: Synovial fluid (SF) analysis is an important tool for the diagnosis of patients with juvenile idiopathic arthritis (JIA). Patients and methods: A retrospective analysis was carried out of cytological features of SF samples obtained from patients with JIA during the period 2008-2016. Results: A total of 102 SF samples from 59 patients were analysed. JIA was more common in females (66%). The most frequent form was persistent oligoarticular JIA (52.5%). The median age at onset was 5 years (IQR 2.4-11.8). SF usually showed an inflammatory pattern (median white blood cells count 11,757/mm3; IQR 4,543-18,800), with a predominance of polymorphonuclear (PMN) cells (61%; IQR 30-75). Eight patients (14%) had white blood cells counts of less than 2,000 cells/mm3, with predominance of mononuclear cells (80%), whereas 3 patients (5%) had white blood cells counts higher than 50,000 cells/mm3, with a predominance of PMN cells (90%). Synovial white blood cells count did not show significant differences among the different forms of JIA. The median synovial white blood cells count in ANA-positive patients was 20% lower than in ANA-negative (9,340 vs. 11,600/mm3; P=.23). The proportion of PMN increased with increasing levels of ESR (P<.001) and/or CRP (P=.03). No significant correlation was found between JADAS-10 and synovial white blood cells count (P=.4). SF obtained from different joints in simultaneous arthrocentesis showed a significant correlation P=.001). Conclusion: SF from JIA patients usually had inflammatory characteristics, although 19% of the patients showed white blood cells counts below 2,000cells/mm3 or higher than 50,000cells/mm3. SF cell count was non-significantly lower in ANA-positive patients, and the proportion of PMN increased with increasing levels of ESR/CRP

    Multi-level alkerdi-zelaieta cave system (Urdazubi/Urdax, Navarre): Base-level incision versus (re)sedimentation

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    Resumen: El sistema kárstico de Alkerdi-Zelaieta tiene un desarrollo de más de 5878 m. En él se engloban distintas cuevas que están genéticamente unidas, pero separadas por la colmatación de las galerías por sedimentos o colapsos. En todo caso, la organización de las galerías formadas en condiciones freáticas indica una mínima disposición de 6 niveles de cuevas, que se han formado en un contexto general de bajada del nivel freático. La formación de cada nivel de cueva está relacionada con procesos paragenéticos, que se deben a un incremento de la carga sedimentaria respecto al caudal hídrico. La variación en el aporte sedimentario se relaciona con cambios climáticos, de forma que cada vez que se repiten las condiciones climáticas propicias se produciría el aumento en la disponibilidad sedimentaria, y con ello, el desarrollo de niveles de cueva en el sistema kárstico. El área fuente de los sedimentos se localiza fundamentalmente en materiales paleozoicos y triásicos del entorno. En este sentido, una vez un nivel de cueva pasa a estar en condiciones vadosas, el sedimento depositado en ella comienza a erosionarse y redepositarse en el nivel inferior que se está formando, reciclándose una y otra vez hasta salir del sistema.Abstract: The Alkerdi-Zelaieta cave system is longer than 5878 m. It is composed by genetically connected caves, which are currently separated by sedimentary filling or collapses. Nevertheless, the disposition of the different subhorizontal passages formed under phreatic conditions shows at least 6 cave-levels, which have been developed in a widespread base-level falling context. The speleogenesis of each cave-level is due to paragenesis, given by an increment on sediment input regarding the stream flow. Changes in sediment input rates are due to climatic changes. Therefore each time that those climatic conditions were reproduced, cave-levels would have been formed. The origin of the sediments are from Paleozoic and Triassic formations of the area. As such, using the meandering conduits that connect different cave-levels, sediments that filled the abandoned galleries were removed and deposited in a lower cave-level that was forming at the moment, being recycled repetitively until they leave the cave-system

    Relevance of gastrointestinal manifestations in a large Spanish cohort of patients with systemic lupus erythematosus: what do we know?

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    SLE can affect any part of the gastrointestinal (GI) tract. GI symptoms are reported to occur in >50% of SLE patients. To describe the GI manifestations of SLE in the RELESSER (Registry of SLE Patients of the Spanish Society of Rheumatology) cohort and to determine whether these are associated with a more severe disease, damage accrual and a worse prognosis. METHODS: We conducted a nationwide, retrospective, multicentre, cross-sectional cohort study of 3658 SLE patients who fulfil =4 ACR-97 criteria. Data on demographics, disease characteristics, activity (SLEDAI-2K or BILAG), damage (SLICC/ACR/DI) and therapies were collected. Demographic and clinical characteristics were compared between lupus patients with and without GI damage to establish whether GI damage is associated with a more severe disease. RESULTS: From 3654 lupus patients, 3.7% developed GI damage. Patients in this group (group 1) were older, they had longer disease duration, and were more likely to have vasculitis, renal disease and serositis than patients without GI damage (group 2). Hospitalizations and mortality were significantly higher in group 1. Patients in group 1 had higher modified SDI (SLICC Damage Index). The presence of oral ulcers reduced the risk of developing damage in 33% of patients. CONCLUSION: Having GI damage is associated with a worse prognosis. Patients on a high dose of glucocorticoids are at higher risk of developing GI damage which reinforces the strategy of minimizing glucocorticoids. Oral ulcers appear to decrease the risk of GI damage. © The Author(s) 2021. Published by Oxford University Press on behalf of the British Society for Rheumatology

    Palaeolithic rock art in Alkerdi 2 cave (Urdazubi/Urdax, Navarra)

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    En el marco del proyecto de «Caracterización del macizo y sistema kárstico de Alkerdi,de la cueva de Alkerdi y de su entorno de protección», se procede a la exploración de la cavidad de Alkerdi 2. Las labores coordinadas han permitido identificar un conjunto de arte parietal asociado a evidencias arqueológicas en superficie. El estilo de las grafías animales grabadas apunta hacia una atribución Gravetiense para la presencia humana. La datación por radiocarbono de uno de los motivos parietales y de un carbón procedente del contexto arqueológico, lo corroboran. Se trata así de la segunda cavidad decorada durante el Paleolítico en Navarra y la muestra artística más antigua de la Comunidad Foral.Within the framework of the characterization project of the massif and karst system of Alkerdi, the Alkerdi cave and its protective environment, the Alkerdi 2 cavity was explored. The coordinated work has made it possible to identify a set of parietal art associated with archaeological evidence on the surface. The style of the engraved animal points towards a Gravettian attribution for human presence. Radiocarbon dating of one of the parietal motifs and a charcoal from the archaeological context corroborate this idea. This is the second cavity decorated during the Paleolithic in Navarre and the oldest artistic remain in the Autonomous Community

    Impact of Biological Agents on Postsurgical Complications in Inflammatory Bowel Disease: A Multicentre Study of Geteccu

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    Background: The impact of biologics on the risk of postoperative complications (PC) in inflammatory bowel disease (IBD) is still an ongoing debate. This lack of evidence is more relevant for ustekinumab and vedolizumab. Aims: To evaluate the impact of biologics on the risk of PC. Methods: A retrospective study was performed in 37 centres. Patients treated with biologics within 12 weeks before surgery were considered “exposed”. The impact of the exposure on the risk of 30-day PC and the risk of infections was assessed by logistic regression and propensity score-matched analysis. Results: A total of 1535 surgeries were performed on 1370 patients. Of them, 711 surgeries were conducted in the exposed cohort (584 anti-TNF, 58 vedolizumab and 69 ustekinumab). In the multivariate analysis, male gender (OR: 1.5; 95% CI: 1.2–2.0), urgent surgery (OR: 1.6; 95% CI: 1.2–2.2), laparotomy approach (OR: 1.5; 95% CI: 1.1–1.9) and severe anaemia (OR: 1.8; 95% CI: 1.3–2.6) had higher risk of PC, while academic hospitals had significantly lower risk. Exposure to biologics (either anti-TNF, vedolizumab or ustekinumab) did not increase the risk of PC (OR: 1.2; 95% CI: 0.97–1.58), although it could be a risk factor for postoperative infections (OR 1.5; 95% CI: 1.03–2.27). Conclusions: Preoperative administration of biologics does not seem to be a risk factor for overall PC, although it may be so for postoperative infections
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