709 research outputs found
La jonction thalweg-cours d'eau : pour une gestion dès l'amont
audience: researcher, professional, student, popularizationCaractérisation des zones à risque d'érosion et de coulée boueuse : bassins versants de la Trouille et de l'Annea
Geostatistical interpolation of daily rainfall at catchment scale: the use of several variogram models in the Ourthe and Ambleve catchments, Belgium
Spatial interpolation of precipitation data is of great importance for hydrological modelling. Geostatistical methods (kriging) are widely applied in spatial interpolation from point measurement to continuous surfaces. The first step in kriging computation is the semi-variogram modelling which usually used only one variogram model for all-moment data. The objective of this paper was to develop different algorithms of spatial interpolation for daily rainfall on 1 km2 regular grids in the catchment area and to compare the results of geostatistical and deterministic approaches. This study leaned on 30-yr daily rainfall data of 70 raingages in the hilly landscape of the Ourthe and Ambleve catchments in Belgium (2908 km2). This area lies between 35 and 693 m in elevation and consists of river networks, which are tributaries of the Meuse River. For geostatistical algorithms, seven semi-variogram models (logarithmic, power, exponential, Gaussian, rational quadratic, spherical and penta-spherical) were fitted to daily sample semi-variogram on a daily basis. These seven variogram models were also adopted to avoid negative interpolated rainfall. The elevation, extracted from a digital elevation model, was incorporated into multivariate geostatistics. Seven validation raingages and cross validation were used to compare the interpolation performance of these algorithms applied to different densities of raingages. We found that between the seven variogram models used, the Gaussian model was the most frequently best fit. Using seven variogram models can avoid negative daily rainfall in ordinary kriging. The negative estimates of kriging were observed for convective more than stratiform rain. The performance of the different methods varied slightly according to the density of raingages, particularly between 8 and 70 raingages but it was much different for interpolation using 4 raingages. Spatial interpolation with the geostatistical and Inverse Distance Weighting (IDW) algorithms outperformed considerably the interpolation with the Thiessen polygon, commonly used in various hydrological models. Integrating elevation into Kriging with an External Drift (KED) and Ordinary Cokriging (OCK) did not improve the interpolation accuracy for daily rainfall. Ordinary Kriging (ORK) and IDW were considered to be the best methods, as they provided smallest RMSE value for nearly all cases. Care should be taken in applying UNK and KED when interpolating daily rainfall with very few neighbourhood sample points. These recommendations complement the results reported in the literature. ORK, UNK and KED using only spherical model offered a slightly better result whereas OCK using seven variogram models achieved better result
ANALYSES DE PROPRIÉTÉS HYDROPHYSIQUES D’UN SOL AGRICOLE SOUMIS À DIFFÉRENTS TRAITEMENTS CULTURAUX DANS LE CADRE DU PROJET SOLRESIDUS
Le projet SOLRESIDUS est une collaboration entre diverses unités au sein de GxABT. Il vise à analyser l’impact du mode de travail du sol (labour/non labour, restitution/exportation des pailles) sur divers paramètres édaphiques/culturaux d’un champ de blé d’hiver (parcelles du Bordia). Le but du projet est de fournir une approche multidisciplinaire à l’analyse de systèmes agricoles. Afin de favoriser l’interaction entre les différentes unités, une base de données regroupant les différents résultats et méthodologies sera créée.
Plus spécifiquement, les mesures touchant aux systèmes Eau-Sol (Unités d’Hydrologie et de Physique) incluent des courbes de rétention (pF), des évaluations d’infiltrabilité (tensio-infiltromètres, anneaux), des profils d’humidité (manuels et automatiques) et une caractérisation de la macro et microstructure porale (scan 3D par tomographie à rayons X).
Ces mesures seront faites tout au long du projet (2 ans), afin d’établir une base solide à la compréhension du comportement hydrophysique d’un sol agricole limoneux. Ceci inclut un suivi des paramètres lors de l’évolution de la culture, mais également une comparaison entre les modalités
Soil redistribution in rural catchment: how fifty years old soil survey can help model improvement
In a context of high urbanization’s pressure in rural zones, landscape modelling of erosion opens interesting perspectives in land use planning. In most cases, validation data are the weak point. In this study, we present how fifty years old soil observations can help progressing towards a more accurate validation of such modelling in rural areas.
As of 1947, a comprehensive systematic survey of the Belgian soil cover was initiated. Field observations were done every 75 meters by soil auger to a standard depth of 125cm (if possible). Map units were delineated on cadastral field survey maps at scale 1:5,000, based on auger observations and landscape context, then generalised on the 1:10,000 topographic base map for a publication at 1:20,000 scale. The legend of the map includes more than 6,000 different soil types and variants. More recently, the Walloon part of this map was digitalised to produce the Digital Soil Map of Wallonia (DSMW).
A 10m resolution DEM was build up in 2009. Its RMSE is 0.8m. Soil erodibility and runoff production maps were derived at the same resolution. A land use map exists at 1:10,000 scale since 2005 and is updated yearly.
We applied the USPED model (Unit Stream Power - based Erosion Deposition) (Moore and Burch, 1986) in a small watershed where first soil observations took place in 1956. New soil observations were done in 2010. The watershed is completely included in a cultivated area.
The model was applied considering a transport capacity limitation proposed by Mitasova and Mitas (1996). Furthermore, we slightly modified it, in order to take into account recent advances in RUSLE factors computations like LS computation proposed by Desmet and Govers (1996) and Nearing (1997).
The spatial distribution of erosion and deposition area produced by the model on the basis of the current DEM is consistent with a comparison between old and recent pedological observations. Furthermore, a comparison between horizons’ thickness in 1956 and 2010 gives spatially distributed quantitative information on erosion and deposition. Nevertheless, some uncertainties remain since the pedological descriptions are based on thickness classes, due to the variability of soil cartographical units, and since the current DEM is itself affected by an uncertainty on the elevation value. Future research will then focus on more accurate elevation data as starting point and then it will become conceivable to model the evolution of watershed elevation including land use and other local anthropogenic structures like hedgerows, ditches or grass strips
Réalisation d'un dispositif expérimental pour l'étude des réactions de captures radiatives induites sur le lithium
Le dispositif décrit consiste en un évaporateur de lithium et un « vobulateur de position de cible ». L'évaporateur nous permet de préparer in situ des cibles exemptes de contaminations. Le « vobulateur » fait décrire à la cible une courbe de Lissajous par rapport au faisceau afin d'éviter la surchauffe de la cible
Alcohol Abstinence Does Not Fully Reverse Abnormalities of Mucosal-Associated Invariant T Cells in the Blood of Patients With Alcoholic Hepatitis
OBJECTIVES:
Alcoholic hepatitis (AH) develops in approximately 30% of chronic heavy drinkers. The immune system of patients with AH is hyperactivated, yet ineffective against infectious diseases. Mucosal-associated invariant T (MAIT) cells are innate-like lymphocytes that are highly enriched in liver, mucosa, and peripheral blood and contribute to antimicrobial immunity. We aimed to determine whether MAIT cells were dysregulated in heavy drinkers with and without AH and the effects of alcohol abstinence on MAIT cell recovery.
METHODS:
MR1 tetramers loaded with a potent MAIT cell ligand 5-(2-oxopropylideneamino)-6-d-ribitylaminouracil were used in multiparameter flow cytometry to analyze peripheral blood MAIT cells in 59 healthy controls (HC), 56 patients with AH, and 45 heavy drinkers without overt liver disease (HDC) at baseline and 6- and 12-month follow-ups. Multiplex immunoassays were used to quantify plasma levels of cytokines related to MAIT cell activation. Kinetic Turbidimetric Limulus Amebocyte Lysate Assay and ELISA were performed to measure circulating levels of 2 surrogate markers for bacterial translocation (lipopolysaccharide and CD14), respectively.
RESULTS:
At baseline, patients with AH had a significantly lower frequency of MAIT cells than HDC and HC. HDC also had less MAIT cells than HC (median 0.16% in AH, 0.56% in HDC, and 1.25% in HC). Further, the residual MAIT cells in patients with AH expressed higher levels of activation markers (CD69, CD38, and human leukocyte antigen [HLA]-DR), the effector molecule granzyme B, and the immune exhaustion molecule PD-1. Plasma levels of lipopolysaccharide and CD14 and several cytokines related to MAIT cell activation were elevated in patients with AH (interferon [IFN]-α, interleukin [IL]-7, IL-15, IL-17, IL-18, IL-23, IFN-γ, and tumor necrosis factor α). Decreased MAIT cell frequency and upregulated CD38, CD69, and HLA-DR correlated negatively and positively, respectively, with aspartate aminotransferase level. MAIT cell frequency negatively correlated with IL-18. HLA-DR and CD38 levels correlated with several cytokines. At follow-ups, abstinent patients with AH had increased MAIT cell frequency and decreased MAIT cell activation. However, MAIT cell frequency was not fully normalized in patients with AH (median 0.31%).
DISCUSSION:
We showed that HDC had a reduction of blood MAIT cells despite showing little evidence of immune activation, whereas patients with AH had a severe depletion of blood MAIT cells and the residual cells were highly activated. Alcohol abstinence partially reversed those abnormalities
Quantitative imaging of concentrated suspensions under flow
We review recent advances in imaging the flow of concentrated suspensions,
focussing on the use of confocal microscopy to obtain time-resolved information
on the single-particle level in these systems. After motivating the need for
quantitative (confocal) imaging in suspension rheology, we briefly describe the
particles, sample environments, microscopy tools and analysis algorithms needed
to perform this kind of experiments. The second part of the review focusses on
microscopic aspects of the flow of concentrated model hard-sphere-like
suspensions, and the relation to non-linear rheological phenomena such as
yielding, shear localization, wall slip and shear-induced ordering. Both
Brownian and non-Brownian systems will be described. We show how quantitative
imaging can improve our understanding of the connection between microscopic
dynamics and bulk flow.Comment: Review on imaging hard-sphere suspensions, incl summary of
methodology. Submitted for special volume 'High Solid Dispersions' ed. M.
Cloitre, Vol. xx of 'Advances and Polymer Science' (Springer, Berlin, 2009);
22 pages, 16 fig
Hepatitis C virus-induced changes in microRNA 107 (miRNA-107) and miRNA-449a modulate CCL2 by targeting the interleukin-6 receptor complex in hepatitis
Hepatitis C virus (HCV)-mediated liver diseases are one of the major health issues in the United States and worldwide. HCV infection has been reported to modulate microRNAs (miRNAs) that control various cell surface receptors and gene-regulatory complexes involved in hepatic inflammation and liver diseases. We report here that specific downregulation of miRNA-107 and miRNA-449a following HCV infection in patients with HCV-mediated liver diseases modulates expression of CCL2, an inflammatory chemokine upregulated in patients with chronic liver diseases, by targeting components of the interleukin-6 receptor (IL-6R) complex. Computational analysis for DNA-bound transcription factors in the CCL2 promoter identified adjacent binding sites for CCAAT/CEBPα, spleen focus-forming virus, proviral integration oncogene (SPI1/PU.1), and STAT3. We demonstrate that CEBPα, PU.1, and STAT3 interacted with each other physically to cooperatively bind to the promoter and activate CCL2 expression. Analysis of IL-6R and JAK1 expression in HCV patients by quantitative PCR showed significant upregulation when there was impaired miRNA-107 and miRNA-449a expression, along with upregulation of PU.1 and STAT3, but not CEBPα. miRNA-449a and miRNA-107 target expression of IL-6R and JAK1, respectively, in vitro and also inhibit IL-6 signaling and impair STAT3 activation in human hepatocytes. Taken together, our results demonstrate a novel gene-regulatory mechanism in which HCV-induced changes in miRNAs (miRNA-449a and miRNA-107) regulate CCL2 expression by activation of the IL-6-mediated signaling cascade, which we propose will result in HCV-mediated induction of inflammatory responses and fibrosis. IMPORTANCE Hepatitis C virus (HCV)-induced hepatitis is a major health concern worldwide. HCV infection results in modulation of noncoding microRNAs affecting major cellular pathways, including inflammatory responses. In this study, we have identified a microRNA-regulated pathway for the chemokine CCL2 in HCV-induced hepatitis. Understanding microRNA-mediated transcriptional-regulatory pathways will result in development of noninvasive biomarkers for better disease prediction and development of effective therapeutics
Search for Branons at LEP
We search, in the context of extra-dimension scenarios, for the possible
existence of brane fluctuations, called branons. Events with a single photon or
a single Z-boson and missing energy and momentum collected with the L3 detector
in e^+ e^- collisions at centre-of-mass energies sqrt{s}=189-209$ GeV are
analysed. No excess over the Standard Model expectations is found and a lower
limit at 95% confidence level of 103 GeV is derived for the mass of branons,
for a scenario with small brane tensions. Alternatively, under the assumption
of a light branon, brane tensions below 180 GeV are excluded
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