27 research outputs found

    Global wealth disparities drive adherence to COVID-safe pathways in head and neck cancer surgery

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    The impact of surgical delay on resectability of colorectal cancer: An international prospective cohort study

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    AIM: The SARS-CoV-2 pandemic has provided a unique opportunity to explore the impact of surgical delays on cancer resectability. This study aimed to compare resectability for colorectal cancer patients undergoing delayed versus non-delayed surgery. METHODS: This was an international prospective cohort study of consecutive colorectal cancer patients with a decision for curative surgery (January-April 2020). Surgical delay was defined as an operation taking place more than 4 weeks after treatment decision, in a patient who did not receive neoadjuvant therapy. A subgroup analysis explored the effects of delay in elective patients only. The impact of longer delays was explored in a sensitivity analysis. The primary outcome was complete resection, defined as curative resection with an R0 margin. RESULTS: Overall, 5453 patients from 304 hospitals in 47 countries were included, of whom 6.6% (358/5453) did not receive their planned operation. Of the 4304 operated patients without neoadjuvant therapy, 40.5% (1744/4304) were delayed beyond 4 weeks. Delayed patients were more likely to be older, men, more comorbid, have higher body mass index and have rectal cancer and early stage disease. Delayed patients had higher unadjusted rates of complete resection (93.7% vs. 91.9%, P = 0.032) and lower rates of emergency surgery (4.5% vs. 22.5%, P < 0.001). After adjustment, delay was not associated with a lower rate of complete resection (OR 1.18, 95% CI 0.90-1.55, P = 0.224), which was consistent in elective patients only (OR 0.94, 95% CI 0.69-1.27, P = 0.672). Longer delays were not associated with poorer outcomes. CONCLUSION: One in 15 colorectal cancer patients did not receive their planned operation during the first wave of COVID-19. Surgical delay did not appear to compromise resectability, raising the hypothesis that any reduction in long-term survival attributable to delays is likely to be due to micro-metastatic disease

    Gestación y la constitución de la maternidad

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    Na gravidez ocorrem mudanças biológicas, somáticas, psicológicas e sociais que influenciam a dinâmica psíquica individual e as demais relações sociais da gestante, e maneira como ela vive estas mudanças repercute intensamente na constituição da maternidade e na relação mãe-bebê. Assim sendo, o objetivo deste estudo foi investigar os sentimentos das gestantes sobre a maternidade, com destaque para a relação entre o período gestacional e a constituição da maternidade. Participaram do estudo 39 gestantes primíparas, entre 19 e 37 anos, no terceiro trimestre de gestação. A análise de conteúdo qualitativa das entrevistas mostrou que as gestantes passaram por importantes transformações corporais, pessoais e interpessoais durante a gestação e vivenciaram intensos sentimentos em relação ao tornar-se mãe. Os achados sugerem que na gestação o processo de constituição da maternidade está em intenso desenvolvimento, assim como o próprio exercício ativo do papel materno.Biological, somatic, psychological and social changes take place in pregnancy which influence the pregnant woman’s psychic dynamics and social relationships. The manner a woman experiences these changes impacts intensely on the constitution of motherhood and mother-infant relationships. Current study investigates pregnant women's feelings concerning motherhood, with special emphasis on the relationship between the pregnancy period and the constitution of motherhood. Thirty-nine primipari pregnant women, aged 19 to 37, in the third trimester of pregnancy, took part in the study. Qualitative content analysis on the interviews showed that pregnant women reported considerable body, personal and interpersonal transformations during pregnancy and experienced intense feelings related to the fact of becoming mothers. Results suggest that in pregnancy the process of constitution of motherhood is in sharp development coupled to the active exercise of the maternal role itself.En el embarazo ocurren cambios biológicos, somáticos, psicológicos y sociales que influyen en la dinámica psíquica individual y en las otras relaciones sociales de la gestante y la manera como ella vive esos cambios repercute intensamente en la constitución de la maternidad y en la relación madre-bebé. Así, el objetivo de esta investigación fue examinar los sentimientos de las mujeres embarazadas sobre la maternidad, con especial atención a la relación entre el período del embarazo y la constitución de la maternidad. Participaron del estudio 39 primíparas embarazadas, entre 19 y 37 años, en el tercer trimestre de gestación. El análisis de contenido cualitativo de las entrevistas mostró que las mujeres embarazadas pasaron por importantes transformaciones corporales, personales e interpersonales durante la gestación y experimentaron intensos sentimientos con respecto a volverse madre. Los resultados sugieren que en la gestación, el proceso de la constitución de la maternidad está en intenso desarrollo, bien como el propio ejercicio activo del rol materno

    Gestación y la constitución de la maternidad

    Get PDF
    Na gravidez ocorrem mudanças biológicas, somáticas, psicológicas e sociais que influenciam a dinâmica psíquica individual e as demais relações sociais da gestante, e maneira como ela vive estas mudanças repercute intensamente na constituição da maternidade e na relação mãe-bebê. Assim sendo, o objetivo deste estudo foi investigar os sentimentos das gestantes sobre a maternidade, com destaque para a relação entre o período gestacional e a constituição da maternidade. Participaram do estudo 39 gestantes primíparas, entre 19 e 37 anos, no terceiro trimestre de gestação. A análise de conteúdo qualitativa das entrevistas mostrou que as gestantes passaram por importantes transformações corporais, pessoais e interpessoais durante a gestação e vivenciaram intensos sentimentos em relação ao tornar-se mãe. Os achados sugerem que na gestação o processo de constituição da maternidade está em intenso desenvolvimento, assim como o próprio exercício ativo do papel materno.Biological, somatic, psychological and social changes take place in pregnancy which influence the pregnant woman’s psychic dynamics and social relationships. The manner a woman experiences these changes impacts intensely on the constitution of motherhood and mother-infant relationships. Current study investigates pregnant women's feelings concerning motherhood, with special emphasis on the relationship between the pregnancy period and the constitution of motherhood. Thirty-nine primipari pregnant women, aged 19 to 37, in the third trimester of pregnancy, took part in the study. Qualitative content analysis on the interviews showed that pregnant women reported considerable body, personal and interpersonal transformations during pregnancy and experienced intense feelings related to the fact of becoming mothers. Results suggest that in pregnancy the process of constitution of motherhood is in sharp development coupled to the active exercise of the maternal role itself.En el embarazo ocurren cambios biológicos, somáticos, psicológicos y sociales que influyen en la dinámica psíquica individual y en las otras relaciones sociales de la gestante y la manera como ella vive esos cambios repercute intensamente en la constitución de la maternidad y en la relación madre-bebé. Así, el objetivo de esta investigación fue examinar los sentimientos de las mujeres embarazadas sobre la maternidad, con especial atención a la relación entre el período del embarazo y la constitución de la maternidad. Participaron del estudio 39 primíparas embarazadas, entre 19 y 37 años, en el tercer trimestre de gestación. El análisis de contenido cualitativo de las entrevistas mostró que las mujeres embarazadas pasaron por importantes transformaciones corporales, personales e interpersonales durante la gestación y experimentaron intensos sentimientos con respecto a volverse madre. Los resultados sugieren que en la gestación, el proceso de la constitución de la maternidad está en intenso desarrollo, bien como el propio ejercicio activo del rol materno
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