31 research outputs found
A geochemical drainage survey of the Fleet granitic complex and its environs
A regional geochemical drainage reconnaissance programme was undertaken over 900 km2 of south-west Scotland
centred on the Fleet granitic complex. Rocks of Ordovician and Silurian age outcrop over the area, into which have been
intruded the Fleet and Loch Doon plutons.
Multi-element analysis of stream sediments and heavy mineral concentrates shows a number of patterns of trace element
distribution related to different lithologies and to mineralisation. Broad scale patterns exhibited by some elements denote
compositional variations within the Lower Palaeozoic sediments and within the Fleet and Loch Doon plutons.
On thebasis of the drainage data the sedimentary rocks have been divided into eight distinct geochemical units each
characterised by different element distribution patterns. The Fleet and Loch Doon plutons have been sub-divided on the
same basis.
Follow-up investigations of drainage anomalies led to the discovery of both structure-controlled and disseminated base
metal mineralisation in the Penkiln drainage basin within the salthernaureole of the Loch Doon granite. The distribution
of Cu, Fâb and Zn to the south and south-west of the Fleet granite suggests a zonation of vein minerahsation, with Cu
prominent adjacent to the granite contact and Fâb and Zn having a wider dispersion away from the granite. Other
anomalies delineate a mineralised lineament that follows the regional strike of the Lower Palaeozoic sediments, southeast
of the Fleet granite
A reconnaissance geochemical drainage survey of the Criffel-Dalbeattie granodiorite complex and its environs
Regional geochemical reconnaissance by stream sediments and panned
concentrates was undertaken over an area of 850 km
2
of south-west Scotland.
Rocks of Ordovician to Permian age are exposed within the area but the major
part is occupied by the Criffel-Dalbeattie granodiorite complex.
Multi-element analysis of the samples collected demonstrates
patterns of trace element distribution related to the geology and
Broad-scale patterns in the distribution of some elements reflect compositional
anumber of
mineralisation.
variations in both the Lower Palaeozoic turbidite sequence and the Criffel-
Dalbeattie granodiorite complex, both of which may be sub-divided into specific
units on the basis of the geochemical data.
The follow-up of copper anomalies in drainage samples from the Black
Stockarton Moor area led to the discovery of porphyry-style copper mineralisation
within an arcuate belt at least 5 km by 1 km within the Black Stockarton Moor
subvolcanic complex and of related disseminated copper mineralisation at Screel
Burn. The area to the west of the Criffel-Dalbeattie plutonic complex is also
characterised by relatively high boron levels in stream sediments reflecting
the widespread occurrence of tourmaline both in association with and peripheral
to the copper mineralisation. Vein mineralisation, usually containing baryte
in addition to base.metals, is also identifiable from the drainage survey at
the eastern margin of the Criffel-Dalbeattie granodiorite; in association with
the Lower Carboniferous rocks along the Solway coast; and within the Lower
Palaeozoic turbidites in the west of the area
Finite Temperature Properties of Quantum Antiferromagnets in a Uniform Magnetic Field in One and Two Dimensions
Consider a -dimensional antiferromagnet with a quantum disordered ground
state and a gap to bosonic excitations with non-zero spin. In a finite external
magnetic field, this antiferromagnet will undergo a phase transition to a
ground state with non-zero magnetization, describable as the condensation of a
dilute gas of bosons. The finite temperature properties of the Bose gas in the
vicinity of this transition are argued to obey a hypothesis of ZERO
SCALE-FACTOR UNIVERSALITY for , with logarithmic violations in .
Scaling properties of various experimental observables are computed in an
expansion in , and exactly in .Comment: 27 pages, REVTEX 3.0, 8 Postscript figures appended, YCTP-xyz
Risk profiles and one-year outcomes of patients with newly diagnosed atrial fibrillation in India: Insights from the GARFIELD-AF Registry.
BACKGROUND: The Global Anticoagulant Registry in the FIELD-Atrial Fibrillation (GARFIELD-AF) is an ongoing prospective noninterventional registry, which is providing important information on the baseline characteristics, treatment patterns, and 1-year outcomes in patients with newly diagnosed non-valvular atrial fibrillation (NVAF). This report describes data from Indian patients recruited in this registry. METHODS AND RESULTS: A total of 52,014 patients with newly diagnosed AF were enrolled globally; of these, 1388 patients were recruited from 26 sites within India (2012-2016). In India, the mean age was 65.8 years at diagnosis of NVAF. Hypertension was the most prevalent risk factor for AF, present in 68.5% of patients from India and in 76.3% of patients globally (P < 0.001). Diabetes and coronary artery disease (CAD) were prevalent in 36.2% and 28.1% of patients as compared with global prevalence of 22.2% and 21.6%, respectively (P < 0.001 for both). Antiplatelet therapy was the most common antithrombotic treatment in India. With increasing stroke risk, however, patients were more likely to receive oral anticoagulant therapy [mainly vitamin K antagonist (VKA)], but average international normalized ratio (INR) was lower among Indian patients [median INR value 1.6 (interquartile range {IQR}: 1.3-2.3) versus 2.3 (IQR 1.8-2.8) (P < 0.001)]. Compared with other countries, patients from India had markedly higher rates of all-cause mortality [7.68 per 100 person-years (95% confidence interval 6.32-9.35) vs 4.34 (4.16-4.53), P < 0.0001], while rates of stroke/systemic embolism and major bleeding were lower after 1 year of follow-up. CONCLUSION: Compared to previously published registries from India, the GARFIELD-AF registry describes clinical profiles and outcomes in Indian patients with AF of a different etiology. The registry data show that compared to the rest of the world, Indian AF patients are younger in age and have more diabetes and CAD. Patients with a higher stroke risk are more likely to receive anticoagulation therapy with VKA but are underdosed compared with the global average in the GARFIELD-AF. CLINICAL TRIAL REGISTRATION-URL: http://www.clinicaltrials.gov. Unique identifier: NCT01090362
Self-emulsifying therapeutic system: a potential approach for delivery of lipophilic drugs
The Cholecystectomy As A Day Case (CAAD) Score: A Validated Score of Preoperative Predictors of Successful Day-Case Cholecystectomy Using the CholeS Data Set
Background
Day-case surgery is associated with significant patient and cost benefits. However, only 43% of cholecystectomy patients are discharged home the same day. One hypothesis is day-case cholecystectomy rates, defined as patients discharged the same day as their operation, may be improved by better assessment of patients using standard preoperative variables.
Methods
Data were extracted from a prospectively collected data set of cholecystectomy patients from 166 UK and Irish hospitals (CholeS). Cholecystectomies performed as elective procedures were divided into main (75%) and validation (25%) data sets. Preoperative predictors were identified, and a risk score of failed day case was devised using multivariate logistic regression. Receiver operating curve analysis was used to validate the score in the validation data set.
Results
Of the 7426 elective cholecystectomies performed, 49% of these were discharged home the same day. Same-day discharge following cholecystectomy was less likely with older patients (OR 0.18, 95% CI 0.15â0.23), higher ASA scores (OR 0.19, 95% CI 0.15â0.23), complicated cholelithiasis (OR 0.38, 95% CI 0.31 to 0.48), male gender (OR 0.66, 95% CI 0.58â0.74), previous acute gallstone-related admissions (OR 0.54, 95% CI 0.48â0.60) and preoperative endoscopic intervention (OR 0.40, 95% CI 0.34â0.47). The CAAD score was developed using these variables. When applied to the validation subgroup, a CAAD score of â€5 was associated with 80.8% successful day-case cholecystectomy compared with 19.2% associated with a CAAD score >5 (pâ<â0.001).
Conclusions
The CAAD score which utilises data readily available from clinic letters and electronic sources can predict same-day discharges following cholecystectomy