36 research outputs found
"Flogging dead horses": evaluating when have clinical trials achieved sufficiency and stability? A case study in cardiac rehabilitation
<p>Abstract</p> <p>Background</p> <p>Most systematic reviews conclude that another clinical trial is needed. Measures of sufficiency and stability may indicate whether this is true.</p> <p>Objectives: To show how evidence accumulated on centre-based versus home-based cardiac rehabilitation, including estimates of sufficiency and stability</p> <p>Methods</p> <p>Systematic reviews of clinical trials of home versus centre-based cardiac rehabilitation were used to develop a cumulative meta-analysis over time. We calculated the standardised mean difference (SMD) in effect, confidence intervals and indicators of sufficiency and stability. Sufficiency refers to whether the meta-analytic database adequately demonstrates that an intervention works - is statistically superior to another. It does this by assessing the number of studies with null results that would be required to make the meta-analytic effect non-statistically significant. Stability refers to whether the direction and size of the effect is stable as new studies are added to the meta-analysis.</p> <p>Results</p> <p>The standardised mean effect difference reduced over fourteen comparisons from a non-significant difference favouring home-based cardiac rehabilitation to a very small difference favouring hospital (SMD -0.10, 95% CI -0.32 to 0.13). This difference did not reach the sufficiency threshold (failsafe ratio 0.039 < 1) but did achieve the criteria for stability (cumulative slope 0.003 < 0.005).</p> <p>Conclusions</p> <p>The evidence points to a relatively small effect difference which was stable but not sufficient in terms of the suggested thresholds. Sufficiency should arguably be based on substantive significance and decided by patients. Research on patient preferences should be the priority. Sufficiency and stability measures are useful tools that need to be tested in further case studies.</p
Internet of things: where to be is to trust
[EN] Networks' creation is getting more and more required, anytime, anywhere. Devices that can participate on these networks can be quite different among them. Sensors, mobiles, home appliances, or other type of devices will have to collaborate to increase and improve the services provided to clients. In the same way, network configuration, security mechanisms establishment, and optimal performance control must be done by them. Some of these devices could have limited resources to work, sometimes even resources restriction not existing, they must work to optimize network traffic. In this article, we center our researching on spontaneous networks. We propose a secure spontaneous ad-hoc network, based on direct peer-to-peer interaction and communities' creation to grant a quick, easy, and secure access to users to surf the Web. Each device will have an identity in the network. Each community will also have an identity and will act as a unity on a world based on Internet connection. Security will be established in the moment they access to the network through the use of the trust chain generated by nodes. Trust is modified by each node on the basis of nodes behaviorLacuesta, R.; Palacios-Navarro, G.; Cetina Englada, C.; Peñalver Herrero, ML.; Lloret, J. (2012). Internet of things: where to be is to trust. EURASIP Journal on Wireless Communications and Networking. (203):1-16. doi:10.1186/1687-1499-2012-203S116203Lipnack J, Stamps J: Virtual Teams: Researching Across Space, Time, and Organizations with Technology. New York: John Wiley and Sons; 1997.Ahuja MK, Carley KN: Network structure in virtual organizations, organization science, Vol. 10, No. 6, Special Issue: Communication Processes for Virtual Organizations, November–December. 1999, 741-757.Mowshowitz A: Virtual organization. Commun ACM 1997, 40(9):30-37. 10.1145/260750.260759Preuß S: CH Cap, Overview of spontaneous networking-evolving concepts and technologies, in Rostocker Informatik-Berichte. Rostock: Fachbereich Informatik der Universit; 2000:113-123.Feeney LM, Ahlgren B, Westerlund A: Spontaneous networking: an application-oriented approach to ad hoc networking. IEEE Commun Mag 2001, 39(6):176-181. 10.1109/35.925687Latvakoski J, Pakkala D, Pääkkönen P: A communication architecture for spontaneous systems. IEEE Wirel Commun 2004, 11(3):36-42. 10.1109/MWC.2004.1308947Mani M, Nguyen A-M, Crespi N: SCOPE: a prototype for spontaneous P2P social networking. Proceedings of 8th IEEE International Conference on Pervasive Computing and Communications Workshops (PERCOM Workshops) 2010, 220-225.Legendre F, de Amorim MD, Fdida S: Implicit merging of overlapping spontaneous networks. Proceedings of Vehicular Technology Conference 2004, 3050-3054.Zarate Silva VH, De Cruz Salgado EI, Ramos Quintana F: AWISPA: an awareness framework for collaborative spontaneous networks. 36th Annual Frontiers in Education Conference 2006, 27-31.Perkins CE, Bhagwat P: Highly dynamic destination sequenced distance-vector routing (DSDV) for mobile computers. Proceedings of the Conference on Communications Architectures, Protocols and Applications (SIGCOMM’94 1994, 234-244.Johnson DB, Maltz DA, Broch J: DSR: The Dynamic Source Routing Protocol for Multihop Wireless Ad Hoc Networks. Boston, MA: Ad Hoc Networking (Addison-Wesley Longman Publishing; 2001.Perkins C, Belding-Royer E, Das S: Ad hoc on-demand distance vector (AODV) routing, RFC 3561. 2003.Park V, Corson MS: IETF MANET Internet Draft “draft-ietf-MANET-tora-spe03.txt”, November 2000. 2012. Accessed March http://tools.ietf.org/html/draft-ietf-manet-tora-spec-03Viana AC, De Amorim MD, Fdida S, de Rezende JF: Self-organization in spontaneous networks: the approach of DHT-based routing protocols. Ad Hoc Networks 2005, 3(5):589-606. 10.1016/j.adhoc.2004.08.006Lacuesta R, Peñalver L: IP addresses configuration in spontaneous networks. In Proceedings of the 9th WSEAS International Conference on Computers. Athens, Greece; 2005:1-6.Alvarez-Hamelin JI, Viana AC, de Amorim M Dias: Architectural considerations for a self-configuring routing scheme for spontaneous networks, Technical Report 1. 2005.Lacuesta R, Peñalver L: Automatic configuration of ad-hoc networks: establishing unique IP link-local addresses. In Proceedings of the International Conference on Emerging Security Information, Systems and Technologies (SECURWARE’07). Valencia, Spain; 2007:157-162.Foulks EF: Social network therapies and society: an overview. Contemp Fam Therapy 1985, 3(4):316-320.IBM: A Smarter Planet. 2012. http://www.ibm.com/smarterplanetMontenegro G, Kushalnagar N, Hui J, Culler D: RFC 4944: Transmission of IPv6 Packets over IEEE 802.15.4 Networks. 2007.Alcaraz C, Najera P, Lopez J, Roman R: Wireless Sensor Networks and the Internet of Things: Do We Need a Complete Integration?, 1st International workshop on the security of The internet of Things (SecIoT). tokyo (Japan); 2010. . Accessed January 2012 1er International Workshop on the Security of The Internet of Things (SecIoT 2010) http://www.nics.uma.es/seciot10/files/pdf/alcaraz_seciot10_paper.pdfFerscha A, Davies N, Schmidt A, Streitz N: Pervasive Socio-Technical Fabric. Procedia Computer Science 2011, 7: 88-91.Hubaux JP, Buttyán L, Capkun S: The quest for security in mobile ad-hoc networks, in Proceedings of the ACM Symposium on Mobile Ad-hoc Networking and Computing. 2001, 146-155.Wang Y, Varadharajan V: Interaction trust evaluation in decentralized environments, e-commerce and web technologies. In Proceedings of 5th International Conference on Electronic Commerce and Web Technologies, vol LNCS 3182. Springer; 2004:144-153.Jimin L, Junbao L, Aiguo A, Zhenpeng L: Two-way trust evaluation based on feedback. in Conference on Logistics Systems and Intelligent Management 2010, 3: 1910-1914.Daskapan S, Nurtanti I, Van den Berg J: Trust algorithms in P2P file sharing networks. Int J Internet Technol Secured Trans 2010, 2(1–2):174-200.Maña A, Koshutanski H, Pérez EJ: A trust negotiation based security framework for service provisioning in load-balancing clusters. Comput Secur 2012, 31(1):4-25. 10.1016/j.cose.2011.11.006Stajano F, Anderson R: The resurrecting duckling security issues for ad-hoc wireless networks. Security Protocols, 7th International Workshop Proceedings, Lecture notes in Computer Science, LNCS 1296 1999, 172-194.Balfanz D, Smetters DK, Stewart P, ChiWong H: Talking to strangers: authentication in ad-hoc wireless networks, in Symposium on Network and Distributed Systems Security (NDSS’02). San Diego, CA; 2002.Capkun S, Hubaux JP, Buttyán L: Mobility helps security in ad-hoc networks. In Proceedings of the 4th ACM international symposium on Mobile ad hoc networking & computing. MD, USA: Annapolis; 2003:46-56.Metzger MJ: Privacy, trust, and disclosure: exploring barriers to electronic commerce. J Comput-Mediat Commun 2004, 9(4). http://jcmc.indiana.edu/vol9/issue4/metzger.html 2004, 9(4)
A higher effort-based paradigm in physical activity and exercise for public health: making the case for a greater emphasis on resistance training
It is well known that physical activity and exercise is associated with a lower risk of a range of morbidities and all-cause mortality. Further, it appears that risk reductions are greater when physical activity and/or exercise is performed at a higher intensity of effort. Why this may be the case is perhaps explained by the accumulating evidence linking physical fitness and performance outcomes (e.g. cardiorespiratory fitness, strength, and muscle mass) also to morbidity and mortality risk. Current guidelines about the performance of moderate/vigorous physical activity using aerobic exercise modes focuses upon the accumulation of a minimum volume of physical activity and/or exercise, and have thus far produced disappointing outcomes. As such there has been increased interest in the use of higher effort physical activity and exercise as being potentially more efficacious. Though there is currently debate as to the effectiveness of public health prescription based around higher effort physical activity and exercise, most discussion around this has focused upon modes considered to be traditionally ‘aerobic’ (e.g. running, cycling, rowing, swimming etc.). A mode customarily performed to a relatively high intensity of effort that we believe has been overlooked is resistance training. Current guidelines do include recommendations to engage in ‘muscle strengthening activities’ though there has been very little emphasis upon these modes in either research or public health effort. As such the purpose of this debate article is to discuss the emerging higher effort paradigm in physical activity and exercise for public health and to make a case for why there should be a greater emphasis placed upon resistance training as a mode in this paradigm shift
Changes in weight, physical activity, sedentary behaviour and dietary intake during the transition to higher education: a prospective study
International Physical Activity Questionnaire: Reliability and Validity of the Turkish Version
PHYSICAL INACIVITY IN ADULTS WITH RHEUMATIC DISEASES
15th Annual European Congress of Rheumatology (EULAR) -- JUN 11-14, 2014 -- Paris, FRANCEWOS: 000346919806511
PHYSICAL ACTIVITY LEVEL AND PHYSICAL FITNESS IN PATIENTS WITH RHEUMATOID ARTHRITIS
WOS: 000331587905577
THE EFFECTS OF AEROBIC EXERCISE TRAINING ON PAIN AND DISABILITY FROM OSTEOARTHRITIS OF THE KNEE IN POSTMENOPAUSAL WOMEN
Congress of the European-League-Against-Rheumatism (EULAR) -- JUN 13-16, 2018 -- Amsterdam, NETHERLANDSWOS: 000444351005530…European League Against Rheumatis
Muscle tibialis anterior fatigue protocol effects on kinetic and kinematic parameters of gait and balance: a laboratory study
Comparison Of Supervised Exercise Training And Home-Based Exercise Training In Chronic Heart Failure
Objective: This study was planned to compare the outcomes between supervised and home-based exercise training in patients with chronic heart failure. Methods: The study was conducted at the Department of Physical Therapy in Ankara University, Faculty of Medicine, Turkey between 2000 and 2001. Twenty-two patients with stable chronic heart failure were randomly assigned to the supervised exercise training group (n=11) or the home-based exercise training group (n=11). Symptom-limited maximal exercise tests with gas exchange analysis were carried out before randomization. Work load equivalent to 60% of achieved peak heart rate at the tests was determined as exercise training work load for each subject. Both groups participated in a program of 3 exercise training sessions per week for 3 months. The exercise tests were repeated after 3 months. Results: After training, peak exercise duration increased significantly in the supervised exercise training group and the home-based exercise training group (p0.05). Conclusion: Supervised and home-based exercise training enhanced exercise capacity in patients with chronic heart failure. The training program must be tailored to each patient's specific limitations, individual needs and possibilities. Home-based exercise training may be a training alternative to stable chronic heart failure patients who prefer not to participate in an outpatient supervised training program.Wo