56 research outputs found

    Photochemical C–H activation: generation of indole and carbazole libraries, and first total synthesis of clausenawalline D

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    The photolysis of N-aryltriazoles and N-arylbenzotriazoles leads to indoles and carbazoles, respectively. Because libraries of triazoles can be accessed rapidly, for example by the copper-catalyzed [3+2] cycloaddition reaction between alkynes and azides, this reaction allows the preparation of indoles in a single operation, by the simultaneous photolysis of the precursor library. As an example of such a synthesis of carbazoles, we prepared for the first time clausenawalline D, an antimalarial alkaloid that was recently isolated

    COOPERATIVITY IN CATALYSIS: CO-CATALYST ASSISTED PALLADIUM-CATALYZED TRANSFORMATIONS

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    Ph.DDOCTOR OF PHILOSOPHY (FOS

    Organocatalytic enamide-azide cycloaddition reactions: Regiospecific synthesis of 1,4,5-trisubstituted-1,2,3-triazoles

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    10.1002/chem.201002775Chemistry - A European Journal17133584-3587CEUJ
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