Model Based Prioritization Technique for Component Testing

To test modified system through outdated test suite regression test process is required. However, this process of retesting takes lot of time and resources because test suite size has been large. Due to this time, consuming nature this process is not efficient for large test suite. Therefore, there is need of best test case prioritization technique to solve issue regarding retesting for large test suite. This technique has been use to evaluate test cases like higher priority test cases executed before lower priority. Main motive behind this work is to recognize faults at earlier stage so that the debuggers can begin their work earlier. In this paper, we propose a new prioritization technique for test cases to perform regression testing for Component Specific Software System (CBSS). Prim’s and Kruskal Algorithm are used

CONCEPT OF IMPROVING STRENGTH IN AYURVEDA W.S.R IMUNITY

Ayurveda is the science of human health and disease. It deals with comfort, discomfort, physiological and pathological aspect of life. The word immunity means the strength of protecting from infectious diseases. The immune system evolved as defense system to protect body from invading pathological microorganisms and malignant diseases. Strong immunity is the key for maintaining stability in health with the changing season. Vyadhikshamatva is described in Ayurveda and this concept is considered equivalent to immunity. Normal condition of kapha, Bala and ojas are also similar to immunity. Vyadhikshamatva literally means resistance (ksamatva) against disease (vyadhi). Physical and mental resistance to disease is of enormous significance for all living being, it regulates both prevention against and rapid recovery from diseases. Ojas is final and excellence of the product dhatu and vyadhiksamatva depends on it. Innate immunity may be correlated to sahajabala and kalajabala may be correlated to acquired immunity. Here is a review of Ayurvedic texts regarding immunity and concept of Vyadhiksamatva which depends on normal dosa, equilibrium state of dhatu, normal agnibala and ojas etc

Qualities of teachers in Ayurvedic prospect

Teacher is the heart of the education system. In Ayurveda teacher not only create good disciple but also a good Vaidya (physician). In old generation of Guru-Shishya Parampara or in the computerized modern era, Teacher is undisputedly the best among the source of knowledge. One of the primes of any successful education system is the teacher. In medical branches like Ayurveda, one who has the sharp observing capacity can develop the qualities of good teaching. Specially in the field of Ayurveda where the classical text, though the centuries old still stand to be true require the efforts of learned teacher to impart knowledge which is based on his own inferences and experience suitable to the modern era. When one refers the quality of teacher and examiner it looks like some quite identical because who is well aware of the knowledge (teacher) can also become the good examiner of subject, object or knowledge. Ideal author of ancient text Charaka Samhita has truly emphasized on Pariksha i.e. the process of examination. Need of these qualities are to be elaborated more in today's era. These qualities can be developed through the training programs specially conducted in the field of Ayurveda also

A Prospective Study of Profile of Agricultural Orthopaedic Injuries in North India in a Tertiary Care Centre

Background: Over time agriculture has transformed into an industry, both in scale and mechanization. Growing demand for agricultural yield and increasing mechanization has led to growth in the numbers of agricultural accidents and injuries causing significant morbidity and economical loss. Aim: To study the causes, patterns, outcomes of injuries due to agricultural accidents, their effect on the productivity of the victims, and to suggest possible remedial measures, a prospective study was undertaken. Methods: A total of 106 patients reporting agricultural injuries (AI) over 14 months in 2019-20 were enrolled and data was recorded on a pre-structured proforma. Results: With the preponderance of male victims, educational status, skill levels, lighting & climatic conditions, intoxication and fatigue were found to be major determinants in the causation of injuries with upper limbs being the predominantly involved part (75.47%) and most of the cases ended up requiring some form of surgery (88.68%). Agricultural machinery (56.60%) was the main cause of AI and Chaff Cutter Machine caused the maximum AI (37.73%). Amputations were the most common injuries sustained (47.16%). Agricultural injuries affected the range of motion of body parts (32.07%) and work (58.49%) & household activities (49.05%); thus impairing work efficiency and economy. Conclusion: The present study highlights the need for a robust surveillance and data analysis leading to better design of farming machinery and equipment, more relevant education and training systems, stronger legislations as well as a comprehensive rehabilitative program aimed at reducing the socio-economic burden caused by agricultural injuries

Serum Uric Acid Levels in Acute Myocardial Infarction: A Comprehensive Study

Acute myocardial infarction (AMI), a potentially fatal heart disease, has a complicated pathogenesis. The end product of purine metabolism, serum uric acid, has been suggested as a possible biomarker for the severity and prognosis of AMI. The purpose of this study is to examine the association between several clinical indicators in AMI patients and serum uric acid levels. This single-center observational research enrolled 100 AMI patients in total. Clinical information was gathered, including demographic information, primary complaints, prior medical history, vital signs, and laboratory results. Upon admission, serum uric acid levels were assessed. To evaluate the relationship between serum uric acid and the severity of AMI, statistical analysis including correlation tests and subgroup comparisons were carried out. The study cohort had a male majority (76%) consistent with the demographics of the average AMI. The most frequent primary complaint (66%) was chest discomfort, while the most common comorbidities were hypertension (35%) and Type 2 diabetes mellitus (28%). Serum uric acid levels and Killip classification, a measure of AMI severity, had a strong correlation. A severer course of AMI was linked to elevated blood uric acid levels (>5.7 mg/dl). Higher serum uric acid levels were associated with patients who had more severe myocardial injury and positive correlations between uric acid levels and cardiac enzymes (CPK MB) and Troponin I. As a result of our research, blood uric acid levels may be useful for predicting prognosis in AMI patients. Increased AMI severity and worse outcomes are linked to elevated blood uric acid. The underlying processes and therapeutic implications of this connection require further study. Assessment of serum uric acid may help with risk stratification and individualized treatment choices for AMI patients

Post Disaster Management of Mithi River Flood after July -2005 by HAVOC

The disaster of Mumbai, July 2005 a galvanised the concerned agencies into recognising the importance of the river, which in fact flows through the heart of Mumbai Suburbs. The authorities were willing now to recognise that the Mithi was a "river" and not a "nalla". The Mithi River Development and Protection Authority was established to initiate the study to identify the causes of pollution affecting the river and to suggest remedial measures. The authority conducted and environmental survey of the Mithi River to determine the pollution level of its water. I have tried to analyse the situation and have suggested guidelines for immediate actions as well as for long term measures. I have refrained from working out specific details of any proposals and it will be done as required by the concerned public agencies keeping in view of the guidelines suggested in this paper. Ours has not been a fault finding mission, but a serious exercise to understand as to which deficiencies need to be overcome, so as to be able to face calamitous situations as on 26th and 27th July,2005 in a better prepared way. We hope that our findings will help Mumbaikar?s to move in the right direction rapidly and with confidence

Concept of Mahagad in Ayurveda w.s.r. to Bhagandara (Fistula-In-Ano)

In Samhitas many concepts are explained as Leshokta (incompletely explained) or they have Linartha i.e. concept is not elaborated or proper meaning is difficult to understand. So there is a need to explore such concept to understand the vision of Ayurveda. The term ‘Mahagada’ is used as ‘Visheshana (attribute)’ for few diseases in various Ayurvedic Samhitas. Original Samhitas shows very little information regarding the term ‘Mahagada’. The concept of ‘Mahagada’ is useful to decide prognosis of diseases. Mahagada is a group of diseases having incurability, primarily due to development of complications. The conceptual study shows belief of ancient Ayurvedic Acharyas regarding concept of Mahagada and clinical survey was done to support the concept. On the basis of collected data, efforts were made to throw light on the concept of Mahagada

Analysis of Labour Productivity in Construction Sector around Mumbai region

Productivity is an important aspect of construction industry that may be used as an index for efficiency of production. Efficient management of construction resources can lead to higher productivity which can help to achieve cost and time saving. Construction is labour oriented industry. It heavily relies on the skills of its workforce. The labour is industry’s most valuable asset. It is important to improve efficiency of production by improving productivity of labour. Aim of this paper is to give the data collection for calculation of labour productivity. The data have been collected by using time study technique in Mumbai region. Method study for placing and binding the reinforcement of column has been done previously. Applying the changes in method the data have been again collected and analysis for productivity have done which results in saving of project time, labour cost with maintaining quality of work

Topographic controls on the development of contemporaneous but contrasting basin-floor depositional architectures

Sediment-laden gravity-driven-flow deposits on the basin floor are typically considered to form either discrete lobes that stack compensationally, or packages of laterally extensive beds, commonly termed “sheets.” These end-member stacking patterns are documented in several basinfills. However, whether they can coexist in a single basin, or there are intermediate or transitional stacking patterns, is poorly understood. An analysis of depositional architecture and stacking patterns along a 70 km dip-oriented transect in the Upper Broto Turbidite System (Jaca Basin, south-central Pyrenees, Spain), which displays disparate stacking patterns in contemporaneous strata, is presented. Proximal and medial deposits are characterized by discrete packages of clean sandstones with sharp bed tops which exhibit predictable lateral and longitudinal facies changes, and are interpreted as lobes. Distal deposits comprise both relatively clean sandstones and hybrid beds that do not stack to form lobes. Instead, localized relatively thick hybrid beds are inferred to have inhibited the development of lobes. Hybrid beds developed under flows which were deflected and entrained carbonate mud substrate off a carbonate slope that bounded the basin to the south; evidence for this interpretation includes: 1) divergent paleoflow indicators and hummock-like features in individual beds; 2) a decrease in hybrid-bed thickness and abundance away from the lateral confining slope; 3) a carbonate-rich upper division, not seen in more proximal turbidites. The study demonstrates the co-occurrence of different styles of basin-floor stacking patterns in the same stratigraphic interval, and suggests that characterization of deep-water systems as either lobes or sheets is a false dichotomy

MUC1 expression and anti-MUC1 serum immune response in head and neck squamous cell carcinoma (HNSCC): a multivariate analysis

BACKGROUND: HNSCC progression to adjacent tissue and nodes may be mediated by altered glycoproteins and glycolipids such as MUC1 mucin. This report constitutes a detailed statistical study about MUC1 expression and anti-MUC1 immune responses in relation to different clinical and pathological parameters which may be useful to develop new anti HNSCC therapeutic strategies. PATIENTS AND METHODS: Fifty three pre treatment HNSCC patients were included: 26 (49.1%) bearing oral cavity tumors, 17 (32.1%) localized in the larynx and 10 (18.8%) in the pharynx. Three patients (5.7%) were at stage I, 5 (9.4%) stage II, 15 (28.3%) stage III and 30 (56.6%) at stage IV. MUC1 tumor expression was studied by immunohistochemistry employing two anti-MUC1 antibodies: CT33, anti cytoplasmic tail MUC1 polyclonal antibody (Ab) and C595 anti-peptidic core MUC1 monoclonal antibody. Serum levels of MUC1 and free anti-MUC1 antibodies were detected by ELISA and circulating immune complexes (CIC) by precipitation in polyethylene glycol (PEG) 3.5%; MUC1 isolation from circulating immune complexes was performed by protein A-sepharose CL-4B affinity chromatography followed by SDS-PAGE and Western blot. Statistical analysis consisted in Multivariate Principal Component Analysis (PCA); ANOVA test (Tukey's test) was employed to find differences among groups; nonparametrical correlations (Kendall's Tau) were applied when necessary. Statistical significance was set to p < 0.05 in all cases. RESULTS: MUC1 cytoplasmic tail was detected in 40/50 (80%) and MUC1 protein core in 9/50 (18%) samples while serum MUC1 levels were elevated in 8/53 (15%) patients. A significant statistical correlation was found between MUC1 serum levels and anti-MUC1 IgG free antibodies, while a negative correlation between MUC1 serum levels and anti-MUC1 IgM free antibodies was found. Circulating immune complexes were elevated in 16/53 (30%) samples and were also statistically associated with advanced tumor stage. MUC1 was identified as an antigenic component of IgG circulating immune complexes. Moreover, poorly differentiated tumors were inversely correlated with tumor and serum MUC1 detection and positively correlated with node involvement and tumor mass. CONCLUSION: Possibly, tumor cells produce MUC1 mucin which is liberated to the circulation and captured by IgG antibodies forming MUC1-IgG-CIC. Another interesting conclusion is that poorly differentiated tumors are inversely correlated with tumor and serum MUC1 detection