Automated Slope Stability Analysis of Zoned Dams

The study pertains to the pseudo-static stability analysis of zoned dams with geologic discontinuities in the foundation. Sequential unconstrained minimization technique in conjunction with Janbu\u27s generalized procedure of slices has been used for finding the critical slip surface and the corresponding minimum factor of safety. The method has been found to be quite efficient in solving such problems

Economic impact of dissemination of management strategies for sucking insect pests on transgenic cotton in Punjab, India

Integrated pest management (IPM) strategies for the management of sucking insect pests were disseminated in 36 villages of three districts of Punjab during 2008 to 2010. Adoption of IPM strategies led to reduction in the population of jassid, whitefly and mealybug in IPM villages. Mean population of jassid was 0.62 and 1.60 nymphs per three leaves, whitefly 1.11 and 2.53 adults per three leaves and mealybug 0.53 and 1.03 per 2.5 cm of central shoot in IPM and non-IPM villages, respectively. Mean population of spiders, chrysoperla, coccinellids and predatory bugs was 0.65, 0.13, 0.15 and 0.04 in IPM villages and 0.29, 0.09, 0.06 and 0.00 per plant in non-IPM villages, respectively. IPM strategies resulted in the 47.69 and 50.56 per cent reduction in number of spray and cost of spray in IPM villages over non-IPM villages. The average cost of cultivation was Rs. 21324 ha−1 in IPM villages, as compared to non-IPM villages (Rs. 23774.67 ha−1). Average seed cotton yield in IPM villages was 2333 kg ha−1 in comparison to non-IPM villages (1959.67 kg ha−1) and average net return in IPM villages was Rs. 57194 ha−1, which was Rs. 15709 more than non-IPM villages

ROLE OF NANOEMULSION FOR SAFE AND COST-EFFECTIVE DELIVERY OF AMPHOTERICIN B

Amphotericin B is a highly effective antifungal agent and its use has been surged drastically due to its effectiveness against a wide range of fungal infections. It is effective against both topical and systemic infections and even this is the only drug having high efficacy against Leishmania, Candida, Aspergillus and many more. Owing to this, the demand of Amphotericin B is gaining momentum. However, this drug possesses numerous drawbacks like toxicity, poor solubility to name a few, due to which its current use is dwindling. So far the numbers of formulations have been marketed in order to triumph over its toxicity and solubility related issues. Unfortunately, no single study conducted hitherto gain success in overcoming its lethal ramifications. Among all formulations, nanoemulsions are at the top to combat all issues related to this drug. Nanoemulsion has shown enhanced stability, reduced cost and toxicity. This review will assimilate complete information on the use of nanoemulsion based formulations of Amphotericin B, its developed formulations and also will enunciate the important considerations and future perspectives. The complete data have been composed from Google Scholar, ScienceDirect and PubMed using the following keywords

Microwave shielding properties of Co/Ni attached to single walled carbon nanotubes

Cobalt/nickel nanoparticles attached to single-walled carbon nanotubes (Co/Ni@SWCNTs) were prepared by dc-arc discharge technique. Co/Ni@SWCNTs were characterized by scanning electron microscopy, high resolution transmission electron microscopy (HRTEM), Raman spectroscopy and energy dispersive X-ray analysis techniques. HRTEM results confirmed attachment of magnetic nanoparticles onto SWCNTs having 1.2 nm diameter. A microwave shielding effectiveness value of 24 dB (blocking >99% radiation) by a 1.5 mm thick sample in the frequency range of 12.4-18 GHz was observed. In order to understand the mechanism of shielding, dielectric andmagnetic attributes of the shielding effectiveness of Co/Ni@SWCNTs have been evaluated. Eddy currents and natural resonances due to the presence of magnetic nanoparticles, electronic polarization and their relaxation, interfacial polarization and unique composition of the shield contributed significantly in achieving good shielding effectiveness. The observed microwave shielding crossed the limit required for commercial applications which suggests that these nanocomposites are promising microwave shielding materials in the Ku band

Disk-Jet Connection in Cygnus X-3

We present the results of a detailed correlation study between the soft X-ray, hard X-ray, and radio emission (obtained from RXTE ASM, BATSE, and GBI observations, respectively) of the bright radio emitting Galactic X-ray binary Cygnus X-3. We detect a very strong positive correlation between the soft X-ray and radio emission during the low-hard and minor flaring periods of the source, and an anti-correlation between the soft and hard X-ray emissions. We present statistical arguments to suggest that the anti-correlation between the radio and hard X-ray emission, reported earlier, is primarily due to their correlation and anti-correlation, respectively, with the soft X-ray emission. We make a wide band X-ray spectral study using the pointed RXTE observations and detect a pivotal behaviour in the X-ray spectrum. We argue that this X-ray spectral pivoting is responsible for the anti-correlation between the soft and hard X-ray emissions. The strong correlation between the soft X-ray and radio emission suggests a close link between the accreting mechanism, plasma cloud surrounding the compact object and the radio emission.Comment: Accepted in A&A Letters. Major revioson of discussion, minor revision of tables and figure

Spectral differences between the radio-loud and radio-quiet low-hard states of GRS 1915+105: possible detection of synchrotron radiation in X-rays

The Galactic microquasar GRS 1915+105 exhibits several episodes of steady X-ray emission characterized by a hard power-law spectrum and intense Quasi Periodic Oscillations. It is known that there are two types of such low-hard states, one with steady radio emission and the other without any significant radio emission. We present the results of a detailed X-ray spectroscopic study of GRS 1915+105, using data from the Rossi X-ray Timing Explorer obtained during various episodes of the low-hard states of the source. We show that there are distinct X-ray spectral differences between the radio-quiet and radio-loud low-hard states of the source. The X-ray spectra of the radio-quiet low-hard state is best described by a model consisting ofa multicolor disk-blackbody and a Comptonized component, whereas the X-ray spectra of radio-loud low-hard state requires a model consisting of three components: a multicolor disk-blackbody, a Comptonized component and a power-law, for statistically and physically acceptable fits. We attempt to model the presence of this additional power-law component as due to synchrotronradiation which is responsible for the radio and infrared radiation from thesource. We show that a simple adiabatically expanding jet model for the synchrotron radiation can account for the observed X-ray flux for reasonable values of the magnetic field and the mass outflow rate. This is the first report of detection of the synchrotron radiation in the X-ray band for this source.Comment: 9 pages 5 figures, Accepted in A&

Anticonvulsant effects of aerial parts of Passiflora incarnata extract in mice: involvement of benzodiazepine and opioid receptors

<p>Abstract</p> <p>Background</p> <p>Passion flower (<it>Passiflora incarnata</it>) is used in traditional medicine of Europe and South America to treat anxiety, insomnia and seizure. Recently, it has shown antianxiety and sedative effects in human.</p> <p>Methods</p> <p>In this study, anticonvulsant effects of hydro- alcoholic extract of Passiflora, Pasipay, were examined by using pentylentetrazole model (PTZ) on mice. Pasipay, diazepam, and normal saline were injected intraperitoneally at the doses 0.4–0.05 mg/kg, 0.5–1 mg/kg and 10 ml/kg respectively 30 minutes before PTZ (90 mg/kg, i.p). The time taken before the onset of clonic convulsions, the duration of colonic convulsions, and the percentage of seizure and mortality protection were recorded. For investigating the mechanism of Pasipay, flumazenil (2 mg/kg, i.p) and naloxone (5 mg/kg, i.p) were also injected 5 minutes before Pasipay.</p> <p>Results</p> <p>An ED₅₀value of Pasipay in the PTZ model was 0.23 mg/kg (%95 CL: 0.156, 0.342). Pasipay at the dose of 0.4 mg/kg prolonged the onset time of seizure and decreased the duration of seizures compared to saline group (p < 0.001). At the dose of 0.4 mg/kg, seizure and mortality protection percent were 100%. Flumazenil and naloxone could suppress anticonvulsant effects of Pasipay.</p> <p>Conclusion</p> <p>It seems that Pasipay could be useful for treatment absence seizure and these effects may be related to effect of it on GABAergic and opioid systems. More studies are needed in order to investigate its exact mechanism.</p