7 research outputs found

    A critical overview of migration and development: The Latin American challenge

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    There is an intense ongoing debate on migration and development in LatinAmerica. This article offers a critical overview of themain perspectives surrounding the Latin American debate across the social sciences. A brief historical background is provided, followed by a characterization of the three main paradigms prevailing in the region: the dominant perspective, grounded in modernization and neoliberal principles; the southern perspective, which has growing influence in the region and is rooted in theLatin American development school; and the transnational approach, which stands in between the first two paradigms and is circumscribed to a meso-level of analysis. The final section highlights five cutting-edge topics that have emerged in the region’s scholarship. The article emphasizes the specificity and the main contributions made by Latin American scholars to understanding and demystifying the complex relationship between migration, development, and human rights

    ESICM LIVES 2016: part two : Milan, Italy. 1-5 October 2016.

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    The impact of surgical delay on resectability of colorectal cancer: An international prospective cohort study

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    AimThe SARS-CoV-2 pandemic has provided a unique opportunity to explore the impact of surgical delays on cancer resectability. This study aimed to compare resectability for colorectal cancer patients undergoing delayed versus non-delayed surgery.MethodsThis was an international prospective cohort study of consecutive colorectal cancer patients with a decision for curative surgery (January-April 2020). Surgical delay was defined as an operation taking place more than 4 weeks after treatment decision, in a patient who did not receive neoadjuvant therapy. A subgroup analysis explored the effects of delay in elective patients only. The impact of longer delays was explored in a sensitivity analysis. The primary outcome was complete resection, defined as curative resection with an R0 margin.ResultsOverall, 5453 patients from 304 hospitals in 47 countries were included, of whom 6.6% (358/5453) did not receive their planned operation. Of the 4304 operated patients without neoadjuvant therapy, 40.5% (1744/4304) were delayed beyond 4 weeks. Delayed patients were more likely to be older, men, more comorbid, have higher body mass index and have rectal cancer and early stage disease. Delayed patients had higher unadjusted rates of complete resection (93.7% vs. 91.9%, P = 0.032) and lower rates of emergency surgery (4.5% vs. 22.5%, P ConclusionOne in 15 colorectal cancer patients did not receive their planned operation during the first wave of COVID-19. Surgical delay did not appear to compromise resectability, raising the hypothesis that any reduction in long-term survival attributable to delays is likely to be due to micro-metastatic disease
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