7,622 research outputs found
Sustainability on campus : knowledge creation through social and environmental reporting
We are very grateful for the comments received by the reviewers of this paper. We appreciate the support received by members of staff and external organizations (due to research procedures we are unable to disclose their names) that contributed to the project. We also would like to express our appreciation to Dr Bill Jackson and Dr Akira Yonekura for their useful comments and feedback. Thanks also go to the students who participated in the project. Without their engagement and passion to the subject this article would not exist. An early version of this paper was presented the 2013 International Enhancement Themes Conference organized by the Scottish Higher Education Academy. We very much appreciated the comments received during this event. We are also grateful for the comments we received at the BAFA 50th Annual conference. We also would like to give our thanks to the Edinburgh Centre for European Financial Studies (EDIFIS) and the QAA Enhancement Theme, who provided small grants to the University Enhancement Group to support this project.Peer reviewedPostprin
Fungi from a groundwater-fed drinking water supply system in Brazil
Filamentous fungi in drinking water distribution systems are known to (a) block water pipes; (b) cause organoleptic biodeterioration; (c) act as pathogens or allergens and (d) cause mycotoxin contamination. Yeasts might also cause problems. This study describes the occurrence of several fungal species in a water distribution system supplied by groundwater in Recife, Pernambuco, Brazil. Water samples were collected from four sampling sites from which fungi were recovered by membrane filtration. The numbers in all sampling sites ranged from 5 to 207 colony forming units (CFU)/100 mL with a mean value of 53 CFU/100 mL. In total, 859 isolates were identified morphologically, with Aspergillus and Penicillium the most representative genera (37% and 25% respectively), followed by Trichoderma and Fusarium (9% each), Curvularia (5%) and finally the species Pestalotiopsis karstenii (2%). Ramichloridium and Leptodontium were isolated and are black yeasts, a group that include emergent pathogens. The drinking water system in Recife may play a role in fungal dissemination, including opportunistic pathogens.The authors acknowledge the collaboration of the Environmental Sanitation Laboratory CTG, especially Mario Kato who provided TOC analysis. The authors thank Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior-Capes in Brazil for the financial support
Studies on the transmission of wesselsbron virus by Aedes (Ochlerotatus) Caballus (Theo.)
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Naked-eye detection as a universal approach to lower the limit of detection of enzyme-linked immunoassays
Colorimetric biosensors for the detection of analytes with the naked eye are required in environmental monitoring, point-of-care diagnostics, and analyses in resources constrained settings, where detection instruments may not be available. However instrument-based detection methods are usually more adequate for detecting small variations in the signal compared to naked-eye detection schemes, and consequently the limit of detection of the latter is usually higher than the former. Here we demonstrate that the limit of detection of colorimetric enzyme-linked immunoassays can be decreased several orders of magnitude when using naked-eye detection instead of a spectrophotometer for detecting the signal. The key step to lower the limit of detection is adding a small volume of chromogenic substrate during the signal generation step. This generates highly colored solutions that can be easily visualized with the naked eye and recorded with the camera of a mobile phone. The proposed method does not require expensive equipment or complex protocols to enhance the signal, and therefore it is a universal approach to lower the limit of detection of colorimetric enzyme-linked immunoassays
Enzyme-coated Janus nanoparticles that selectively bind cell receptors as a function of the concentration of glucose
A method is proposed for controlling the number of nanoparticles bound to cell membranes via RGDS peptide-integrin interactions. It consists of propelling nanoparticles bearing the peptides with enzymes (glucose oxidase), which disrupts biomolecular interactions as a function of the concentration of enzyme substrate (glucose)
Amenable actions, free products and a fixed point property
We investigate the class of groups admitting an action on a set with an
invariant mean. It turns out that many free products admit such an action. We
give a complete characterisation of such free products in terms of a strong
fixed point property.Comment: 12 page
Natural Products from the Lithistida: A Review of the Literature since 2000
Lithistid sponges are known to produce a diverse array of compounds ranging from polyketides, cyclic and linear peptides, alkaloids, pigments, lipids, and sterols. A majority of these structurally complex compounds have very potent and interesting biological activities. It has been a decade since a thorough review has been published that summarizes the literature on the natural products reported from this amazing sponge order. This review provides an update on the current taxonomic classification of the Lithistida, describes structures and biological activities of 131 new natural products, and discusses highlights from the total syntheses of 16 compounds from marine sponges of the Order Lithistida providing a compilation of the literature since the last review published in 2002
Existence of equilibria in countable games: an algebraic approach
Although mixed extensions of finite games always admit equilibria, this is
not the case for countable games, the best-known example being Wald's
pick-the-larger-integer game. Several authors have provided conditions for the
existence of equilibria in infinite games. These conditions are typically of
topological nature and are rarely applicable to countable games. Here we
establish an existence result for the equilibrium of countable games when the
strategy sets are a countable group and the payoffs are functions of the group
operation. In order to obtain the existence of equilibria, finitely additive
mixed strategies have to be allowed. This creates a problem of selection of a
product measure of mixed strategies. We propose a family of such selections and
prove existence of an equilibrium that does not depend on the selection. As a
byproduct we show that if finitely additive mixed strategies are allowed, then
Wald's game admits an equilibrium. We also prove existence of equilibria for
nontrivial extensions of matching-pennies and rock-scissors-paper. Finally we
extend the main results to uncountable games
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