Participação via canais virtuais e mudança institucional na Secretaria do Tesouro Nacional

Dissertação (mestrado)—Universidade de Brasília, Programa de Pós-Graduação em Administração, 2013.Qualquer organização de caráter profissional passa por mudanças institucionais ao longo de sua existência. A Secretaria do Tesouro Nacional (STN) não foge a esta regra, acrescentandose a ela a particularidade de ser um órgão público, cuja comunicação com os cidadãos deve ser presente e atender aos preceitos de eficiência, eficácia e efetividade. Em adição, vive-se um cenário em que cada vez mais pessoas têm acesso aos meios eletrônicos de comunicação. Considerando esse contexto, este trabalho investiga de que forma os canais virtuais de participação individual, tais como twitter e youtube, contribuem para as mudanças institucionais percebidas na STN. Mais do que isso, sob a ótica dos modelos Equilíbrio Pontuado e Garbage Can, visa-se a identificar quais são essas mudanças institucionais por meio da participação dos cidadãos. Para tanto, o recurso metodológico utilizado é o de estudo descritivo, tendo como ferramenta de coleta entrevistas semiestruturadas no sentido de obter as percepções dos gestores da STN sobre o tema. Os resultados obtidos mostram de que forma a STN trabalha a questão da participação, com destaque para os canais virtuais twitter e youtube. Além disso, listam-se as mudanças institucionais percebidas pelos gestores que participaram do trabalho e, por fim, relacionam-se os resultados à literatura existente sobre eficiência na gestão pública. ______________________________________________________________________________________ ABSTRACTAny organization of professional character goes through institutional changes throughout its existence. The National Treasury Secretariat (STN) is no exception to this rule, adding to it the distinction of being a public organization, whose communication with citizens must be present and meet the principles of effectiveness, efficiency and effectiveness. In addition to this, we live in a scenario where more people have access to electronic media. Considering this context, this paper investigates how the virtual channels of individual participation, such as twitter and youtube, contribute to institutional changes in perceived STN. More than that, from the perspective of Punctuated Equilibrium models and Garbage Can, identify what these institutional changes through citizen participation. Thus, the methodological approach used is a descriptive study, and as a tool for collecting structured interviews in order to obtain the perceptions of managers STN on the topic. The results show how the STN works the question of participation. Also, list the institutional changes perceived by managers who participated in the study, and finally, relates results to the existing literature on efficiency in public management

Trichotillomania: a good response to treatment with N-acetylcysteine

Trichotillomania is considered a behavioral disorder and is characterized by the recurring habit of pulling one's hair, resulting in secondary alopecia. It affects 1% of the adult population, and 2 to 4.4% of psychiatric patients meet the diagnostic criteria. It can occur at any age and is more prevalent in adolescents and females. Its occurrence in childhood is not uncommon and tends to have a more favorable clinical course. The scalp, eyebrows and eyelashes are the most commonly affected sites. Glutamate modulating agents, such as N-acetylcysteine, have been shown to be a promising treatment. N-acetylcysteine acts by reducing oxidative stress and normalizing glutaminergic transmission. In this paper, we report a case of trichotillomania with an excellent response to N-acetylcysteine.Univ Fed Sao Paulo, Dept Cosmetol, Trichol Outpatient Clin, Sao Paulo, SP, BrazilUniv Fed Sao Paulo, Dept Cosmetol, Trichol Outpatient Clin, Sao Paulo, SP, BrazilWeb of Scienc

Analysis of two-color photoelectron spectroscopy for attosecond metrology at seeded free-electron lasers

The generation of attosecond pulse trains at free-electron lasers opens new opportunities in ultrafast science, as it gives access, for the first time, to reproducible, programmable, extreme ultraviolet (XUV) waveforms with high intensity. In this work, we present a detailed analysis of the theoretical model underlying the temporal characterization of the attosecond pulse trains recently generated at the free-electron laser FERMI. In particular, the validity of the approximations used for the correlated analysis of the photoelectron spectra generated in the two-color photoionization experiments are thoroughly discussed. The ranges of validity of the assumptions, in connection with the main experimental parameters, are derived

Tunability experiments at the FERMI@Elettra free-electron laser

FERMI@Elettra is a free electron-laser (FEL)-based user facility that, after two years of commissioning, started preliminary users' dedicated runs in 2011. At variance with other FEL user facilities, FERMI@Elettra has been designed to deliver improved spectral stability and longitudinal coherence. The adopted scheme, which uses an external laser to initiate the FEL process, has been demonstrated to be capable of generating FEL pulses close to the Fourier transform limit. We report on the first instance of FEL wavelength tuning, both in a narrow and in a large spectral range (fine- and coarse-tuning). We also report on two different experiments that have been performed exploiting such FEL tuning. We used fine-tuning to scan across the 1s–4p resonance in He atoms, at ≈23.74 eV (52.2 nm), detecting both UV–visible fluorescence (4p–2s, 400 nm) and EUV fluorescence (4p–1s, 52.2 nm). We used coarse-tuning to scan the M4,5 absorption edge of Ge (∼29.5 eV) in the wavelength region 30–60 nm, measured in transmission geometry with a thermopile positioned on the rear side of a Ge thin foil

Periodontal Plastic Surgery to Improve Aesthetics in Patients with Altered Passive Eruption/Gummy Smile: A Case Series Study

Altered passive eruption/gummy smile is a common challenge in patients requiring aesthetic treatment. A specific surgical protocol was designed and tested in patients with altered passive eruption. Standardized preoperative X-rays were used to assess crown length at baseline and to place submarginal incisions. Osseous respective therapy was performed to achieve biological width. Clinical outcomes were recorded 6 months after surgery. Eleven patients with a total of 58 teeth were treated with flap surgery and osseous resective therapy at upper anterior natural teeth. At the last followup, a significant and stable improvement of crown length was obtained when compared to the baseline (P < 0.0001). All patients rated as satisfactory in the final outcomes (final VAS value = 86.6). In conclusion, this study showed that periodontal plastic surgery including osseous resection leads to predictable outcomes in the treatment of altered passive eruption/gummy smile: A careful preoperative planning avoids unpleasant complications and enhances postsurgical stability of the gingival margin

Bunch by Bunch X-Ray Beam Position and Intensity Monitoring Using a Single Crystal Diamond Detector

Diamond is an outstanding material for the production of semitransparent in situ photon beam monitors which can withstand the high dose rates occurring in new generation synchrotron radiation storage rings and in free electron lasers. Here we report on the development of a 500 um thick freestanding, single-crystal chemical vapor deposited diamond detector with segmented electrodes; it exhibits a high resistivity of some 10^15 ohm cm which allows charge integration operations. Using the latter at a frame rate of 8.33 kHz in combination with a needle synchrotron radiation beam and mesh scans, the inhomogeneity of the sensor was found to be of the order of 2%. With a measured electronics noise of 2 pA / Hz^(1/2) a 0.05% relative precision in the intensity measurements (at 1 uA) and a 0.1 um resolution in the position encoding have been estimated. Moreover, the high electron\u2013hole mobility of diamond compared with other active materials enables very fast charge collection. This allowed us to utilize single pulse integration to simultaneously detect the intensity and the position of each synchrotron radiation photon bunch generated by a bending magnet

X-ray micro beam analysis of the photoresponse of an enlarged CVD diamond single crystal

Diamond is one of the most promising materials for developing innovative electronic devices. Chemical vapour deposition (CVD) homoepitaxial growth allows the synthesis of high quality single crystal diamond plates. However, the use of these crystals for electronic applications is hampered by their small area (typically of the order of 10 mm2). Large areas are desired to ensure efficient particle or radiation detection with pixelated devices. By growing a thick CVD layer it is possible to enlarge the initial area of the substrate by a factor of 2 since growth also occurs laterally from the substrate. In this work, by using an X-ray collimated synchrotron radiation beam, the detection and charge collection properties of an enlarged CVD single-crystal diamond are used as a point-to-point probe to study the material quality. It was found that stress and dislocation density are correlated with the detection properties of the enlarged regions. The sensitivity of the device is affected by the vertical-to-lateral growth interface and the enlarged material quality seems to be correlated with the distance from this interface

Virological patterns of hepatitis C virus patients with failure to the current-generation direct-acting antivirals

There are few data on the virological characterisation of patients with failure to current-generation direct-acting antivirals (DAAs), namely elbasvir/grazoprevir, sofosbuvir/velpatasvir and glecaprevir/pibrentasvir. This study aimed to characterise virological patterns in patients with failure to current DAA regimens as well as the efficacy of re-treatment. All 61 consecutive hepatitis C virus (HCV) treatment-naïve patients with failure to current DAAs from January 2018 to February 2019 were enrolled. Sanger sequencing of NS3, NS5A and NS5B proteins was performed using homemade protocols. NS5A resistance-associated substitutions (RASs) were more frequent in the 17 patients treated with sofosbuvir/velpatasvir (89.5%) and 33 patients treated with elbasvir/grazoprevir (97%) compared with the 11 patients treated with glecaprevir/pibrentasvir (18.2%) (P = 0.002 and 0.000, respectively). NS3 RASs were more often detected in the 33 patients with failure to elbasvir/grazoprevir (30.3%) than in the 11 patients treated with glecaprevir/pibrentasvir (9.1%). NS3 RASs were also detected in 12% of sofosbuvir/velpatasvir-treated patients. NS5B RASs were infrequently identified. Of the glecaprevir/pibrentasvir-treated patients, 73% did not show RASs in any HCV regions, a prevalence higher than that observed in those treated with elbasvir/grazoprevir (0%; P &lt; 0.05) or sofosbuvir/velpatasvir (12%; P &lt; 0.05). Of the 61 patients, 21 (34.4%) were re-treated with sofosbuvir/velpatasvir and voxilaprevir. All patients achieved sustained virological response at 12 weeks (SVR12). To our knowledge, this is one of the first real-life studies describing patients who failed current-generation DAAs; the prevalence of RASs differed according to the DAA regimen used, and the efficacy of re-treatment was high

Patients with adrenal insufficiency have cardiovascular features associated with hypovolemia

Context: Patients with adrenal insufficiency (AI) have excess mortality and morbidity, mainly due to cardiovascular (CV) diseases. The mechanisms for this is unclear. Objective: To assess CV structure and function in AI patients on conventional replacement therapy and after switching to once-daily, modified-release hydrocortisone (OD-HC) in comparison with healthy matched controls. Methods: This was a retrospective analysis of 17 adult AI patients (11 with primary AI, 6 with secondary AI) on stable replacement with cortisone acetate [median (minimum, maximum) 33.5 (12.5–50) mg] and, if needed, fludrocortisone [0.1 (0.05–0.2) mg], and 17 healthy matched controls. Ten patients were switched to an equivalent dose of OD-HC. Data from echocardiography, 24 h Holter-ECG and 24 h blood pressure monitoring were collected at baseline and 6 months after the switch to OD-HC. Results: At baseline, AI patients had smaller left ventricular diastolic diameter (47.1 ± 4.2 vs. 51.6 ± 2.3 mm; P = 0.001) and left atrial diameter (34.9 ± 4.7 vs. 38.2 ± 2.6 cm; P = 0.018), and a higher ejection fraction (62.5 ± 6.9% vs. 56.0 ± 4.7%; P = 0.003) than controls. AI patients had lower nocturnal systolic and diastolic blood pressure than controls (108 ± 15 mmHg vs. 117 ± 8 mmHg; P = 0.038 and 65 ± 9 mmHg vs. 73 ± 7 mmHg; P = 0.008, respectively). After the switch to OD-HC, nocturnal diastolic blood pressure normalised. No significant changes were observed in echocardiographic and Holter-ECG parameters following the switch. Conclusions: AI patients on conventional treatment display cardiovascular abnormalities that could be related to hypovolemia. Switch to OD-HC seems to have beneficial effect on blood pressure profile, but no effect on cardiovascular structure and function