Existence of a positive solution for a singular system

We show the existence and nonexistence of positive solutions to a system of singular elliptic equations with Dirichlet boundary condition. This system arises in studies of pattern formation in biology and in the activator-inhibitor model proposed by Gierer-Meinhardt.Conselho Nacional de Desenvolvimento Científico e Tecnológico (Brasil)Ministerio de Educación y Cienci

Inhalable spray-dried chondroitin sulphate microparticles: effect of different solvents on particle properties and drug activity

Spray-drying stands as one of the most used techniques to produce inhalable microparticles, but several parameters from both the process and the used materials affect the properties of the resulting microparticles. In this work, we describe the production of drug-loaded chondroitin sulphate microparticles by spray-drying, testing the effect of using different solvents during the process. Full characterisation of the polymer and of the aerodynamic properties of the obtained microparticles are provided envisaging an application in inhalable tuberculosis therapy. The spray-dried microparticles successfully associated two first-line antitubercular drugs (isoniazid and rifabutin) with satisfactory production yield (up to 85%) and drug association efficiency (60%-95%). Ethanol and HCl were tested as co-solvents to aid the solubilisation of rifabutin and microparticles produced with the former generally revealed the best features, presenting a better ability to sustainably release rifabutin. Moreover, these presented aerodynamic properties compatible with deep lung deposition, with an aerodynamic diameter around 4 μm and fine particle fraction of approximately 44%. Finally, it was further demonstrated that the antitubercular activity of the drugs remained unchanged after encapsulation independently of the used solvent.UID/Multi/04326/2019; SFRH/BD/52426/2013; ED481B 2018/071info:eu-repo/semantics/publishedVersio

Early stages of the roman occupation of Lagos, Portugal, from a Julian-Claudian ceramic context

En los últimos años, como resultado de la progresiva renovación y rehabilitación urbana de la ciudad de Lagos, se han realizado en el centro histórico un importante número de intervenciones arqueológicas de urgencia. Las noticias de nuevos hallazgos se han sucedido en el tiempo destacando para el período romano, las relacionadas con la presencia de varias fábricas de preparados piscícolas en la ribera de la ciudad, especialmente concentradas a lo largo de la calle 25 de Abril y la calle Silva Lopes. A pesar de las continuas informaciones que estas intervenciones han proporcionado todavía quedan por aclarar varias cuestiones relacionadas con las dimensiones de la zona fabril y sus ritmos productivos, especialmente las relacionadas con su fecha de inicio. Una reciente intervención en los nos. 72-78 de la calle 25 de Abril, nos ha permitido gracias a un excepcional contexto cerrado de mediados del s. I, profundizar y esclarecer dichas cuestiones. Además, el conjunto cerámico del pozo se postula como un auténtico “contexto de referencia” para el comercio en la región durante los cuartos centrales del s. I d.C.In recent years, as a result of the ongoing urban development at Lagos, a significant number of rescue excavations have been carried out in the historic centre. New discoveries dating back to Roman times have been made in connection with fish salting factories on the city shores, mainly concentrated along 25 de Abril street and Silva Lopes street. Some historical and archaeological questions related to the dimensions of this industrial area, its productive rhythms and, especially, the starting date of salt fishing activities are still elusive. However, at least the last issue can be partially clarified thanks to the archaeological excavation at number 72-78 of 25 de Abril street, which has provided an exceptional ceramic context from a well dated period back in the middle of the 1st century. In addition to that, this ceramic set can be regarded as an authentic “reference context” for trade in the region during the central years of the 1st century A.D

Public marketing and university marketing : the orientation of universities towards the satisfaction of demand for knowledge from society

La idea del marketing público se genera durante el siglo XX estableciendo un intercambio entre Estado y Sociedad. La Administración Pública diseña programas, bienes y servicios, como contraparte, los ciudadanos ofrecen apoyos mediante impuestos y costos de desplazamiento, tiempo y oportunidad. El marketing universitario, propone un intercambio entre las universidades y los alumnos para satisfacer las demandas de conocimiento y formación técnica-profesional. La problemática abordada en esta propuesta es la satisfacción de necesidades públicas a través del marketing público y, en este contexto, el marketing universitario y las demandas de conocimiento de la sociedad.The notion of public marketing arises in the 20th century and establishes an exchange between State and Society. The Public Administration designs programs, goods and services and, as a counterpart, citizens provide support through taxes and travel, time and opportunity costs. University Marketing proposes an exchange between universities and students in order to satisfy the demands for knowledge and for professional-technical training. The subject under consideration in this proposal is the satisfaction of public needs through public marketing and, within this context, the University marketing and the social demands for knowledge.Fil: Da Viá, Ana. Universidad Nacional de Cuyo. Facultad de Ciencias Políticas y SocialesFil: Arenas , Fernando. Universidad Nacional de Cuyo. Facultad de Ciencias Políticas y SocialesFil: Fernández, Anabel. Universidad Nacional de Cuyo. Facultad de Ciencias Políticas y Sociale

On real-analytic Levi-flat hypersurfaces and holomorphic webs

We investigate holomorphic webs tangent to real-analytic Levi-flat hypersurfaces on compact complex surfaces. Under certain conditions, we prove that a holomorphic web tangent to a real-analytic Levi-flat hypersurface admits a multiple-valued meromorphic first integral. We also prove that the Levi foliation of a Levi-flat hypersurface induced by an irreducible real-analytic curve in the Grassmannian $G(n+1,n)$ extends to an algebraic web on the complex projective space.Comment: 19 page

A educação inclusiva em África. O caso de Cabo Verde

"Publicación de carácter científico, surgida del proyecto de investigación internacional coordinada por la Universidad de Jaén (España) y el Centro Universitario del Sur (Guadalajara, Mexico)

The Effective Lorentzian and Teleparallel Spacetimes Generated by a Free Electromagnetic Field

In this paper we show that a free electromagnetic field living in Minkowski spacetime generates an effective Weitzenbock or an effective Lorentzian spacetime whose properties aredetermined in details. These results are possible because we found using the Clifford bundle formalism the noticeable result that the energy-momentum densities of a free electromagnetic field are sources of the Hodge duals of exact 2-form fields which satisfy Maxwell like equations.Comment: A missing term in Eq.(14) has been inserted and some misprints correcte

Perspectiva temporal e tomada de decisão: um estudo sobre padrões decisórios em adultos argentinos

The first aim of this study was to adapt the MDMQ to Argentinian Spanish and to collect evidence of its validity and reliability; the second was to determine if time perspectives were adequate predictors of decisionmaking styles. A first sample of 536 participants served in the validation process; a second sample of 209 individuals who completed the mdmq and the Brief Zimbardo Time Perspective Inventory (ZTPI) was used to conduct descriptive-correlational and regression analyses. Confirmatory factor analysis corroborated a four-factor model with adequate internal consistency for each subscale. Regression analyses showed that future time perspective positively predicted the display of higher vigilant coping patterns —adaptive and rational decision-making style—. Meanwhile, less futuretime- oriented people were more likely to engage in defensive avoidance mechanisms to reach a decision. Past-negative and present-fatalistic time perspectives were positive predictors of non-vigilant decisionmaking style. It indicates that individuals with an aversive vision over their past experiences and present situation are more likely to engage in emotionally based and avoidant decision-making patterns. These findings support the reliability and construct-related validity of the MDMQ for assessing decision-making styles among Argentinian individuals and set a step for conducting more in-depth research in the field of decisionmaking and time perspective.El primer objetivo de este estudio fue adaptar el MDMQ al español argentino y recolectar evidencia de su validez y confiabilidad; el segundo fue determinar si las perspectivas temporales eran predictores adecuados de los estilos de toma de decisiones. Una primera muestra de 536 participantes sirvió para el proceso de validación y una segunda muestra de 209 individuos completó el mdmq y el Brief Zimbardo Time Perspective Inventory (ZTPI), para un análisis descriptivo-correlacional y de regresión. El análisis factorial confirmatorio corroboró un modelo de cuatro factores con adecuada consistencia interna para cada subescala. Los análisis de regresión mostraron que la perspectiva del tiempo futuro predijo positivamente la aparición de patrones de afrontamiento más vigilantes —estilo de toma de decisiones adaptativo y racional—, mientras que las personas que estaban menos orientadas al tiempo futuro tenían más probabilidades de involucrarse en mecanismos de evitación defensiva para tomar una decisión. Las perspectivas temporales negativas del pasado y fatalistas del presente fueron predictores positivos del estilo de toma de decisiones no vigilante, lo que indicaría que las personas con una visión aversiva sobre sus experiencias pasadas y la situación presente, son más propensas a involucrarse en tipos de toma de decisiones basadas en emociones y evasivas. Estos hallazgos respaldan la confiabilidad y la validez relacionada con el constructo del MEMQ para evaluar los estilos de toma de decisiones entre los argentinos y marcan un paso para realizar investigaciones más profundas en el campo de la toma de decisiones y la perspectiva temporal.O primeiro objetivo deste estudo foi adaptar o MDMQ para o espanhol argentino e coletar evidências de sua validade e confiabilidade; a segunda foi determinar se as perspectivas de tempo eram preditores adequados dos estilos de tomada de decisão. Uma primeira amostra de 536 participantes foi usada para o processo de validação e uma segunda amostra de 209 indivíduos completarou o mdmq e o Brief Zimbardo Time Perspective Inventory (ZTPI) e foi usada para realizar análises descritivas-correlacionais e de regressão. A análise fatorial confirmatória corroborou um modelo de quatro fatores com consistência interna adequada para cada subescala. As análises de regressão mostraram que a perspectiva do tempo futuro previu positivamente o surgimento de padrões de enfrentamento mais vigilantes —estilos de tomada de decisão racionais e adaptativos— enquanto as pessoas menos orientadas para o futuro eram mais propensas a se envolver em mecanismos de enfrentamento de evasão defensiva para tomar uma decisão. Perspectivas temporais negativas do passado e fatalistas do presente foram preditores positivos do estilo de tomada de decisão não vigilante, indicando que pessoas com uma visão aversiva de suas experiências passadas e da situação presente são mais propensas a se envolver em tipos de tomada de decisão baseadas em emoções e padrões evasivos. Essas descobertas apoiam a confiabilidade e a validade relacionada ao construto do MDMQ para avaliar os estilos de tomada de decisão entre os argentinos e marcam um importante passo para realizar pesquisas mais profundas no campo da tomada de decisão e perspectiva de tempo