Efektifitas Pemberdayaan Kelompok Ibu Rumah Tangga Dalam Peningkatan Pengetahuan, Sikap Dan Praktek Pemberantasan Demam Berdarah Dengue Di Kelurahan Adiarsa Barat Kabupaten Karawang Provinsi Jawa Barat

. Adiarsa Barat village is one of endemic area of the Dengue Haemorrhagic Fever (DHF) in Karawang. That village had not touched by community empowerment yet. The purpose of this research was to knoweffectiveness of housewives empowerment for eradication of DHF with breeding site control. This research was an experimental quation, with intervention in one location and control in other. The final result was hoped that the respondents would increase of knowledge, attitude and practice. The data of housewife behaviour was collected by intervew. This research found that there was the increase of housewife's group behaviour, followed by the increase of housewifes behaviour at intervention area with P value < 0,05. Although housewifes behaviour at control area hasn't increase with P value> 0,05. This reaserch suggested that people participation needed to be identified first then monitored periodically, so that their behaviour to eradicate DHF disease would be a habit or permanent

Simulations of the High-Energy Beam-Transport (HEBT) section at FRANZ

The neutron source FRANZ (Frankfurter Neutronenquelle am Stern-Gerlach-Zentrum), which is currently under construction, will be the neutron source with the highest intensity in the nuclear-astrophysically relevant energy region. The TraceWin code was used to design the High-Energy Beam-Transport section with regard to the experimental requirements at different target positions

Regioselective Glycosylation Strategies for the Synthesis of Group Ia and Ib Streptococcus Related Glycans Enable Elucidating Unique Conformations of the Capsular Polysaccharides

Group B Streptococcus serotypes Ia and Ib capsular polysaccharides are key targets for vaccine development. In spite of their immunospecifity these polysaccharides share high structural similarity. Both are composed of the same monosaccharide residues and differ only in the connection of the Neu5Acα2-3Gal side chain to the GlcNAc unit, which is a β1-4 linkage in serotype Ia and a β1-3 linkage in serotype Ib. We described development of efficient regioselective routes for GlcNAcβ1-3[Glcβ1-4)]Gal synthons giving access to different GBS Ia and Ib repeating unit frameshifts. These glycans were used to probe the conformation and molecular dynamics of the two polysaccharides, highlighting the different presentation of the protruding Neu5Acα2-3Gal moieties on the polysaccharide backbones and a higher flexibility of Ib polymer compared to Ia which can impact epitope exposure.Bio-organic Synthesi

Flogging tired horses: who wants whipping and who would walk away if whipping horses were withheld?

Recent studies have cast doubt on the effectiveness of whipping horses during races and this has led to questions concerning its continuing justification. Furthermore, it has been argued that whipping tired horses in racing is the most televised form of violence to animals. The present study used de-identified data from a recent independent Australian poll (n = 1,533) to characterise the 26% of respondents (113 females and 271 males) who support the whipping of racehorses and the 10% of racing enthusiasts in the sample (44 females and 63 males) who would stop watching races and betting on them if whipping were banned. Logistic regression models examining associations between age, gender, and income level of respondents demonstrated that those who support racehorse whipping are significantly more likely to be male. Among racing enthusiasts who would stop watching races and betting on them if whipping were banned, those in the lowest income bracket were over-represented. The more frequently respondents attended races or gambled on them, the more likely they were to agree that horses should be hit with a whip during the normal course of a race. These findings align with previous studies of violence among men and women but may also be attributed to male support of traditional gambling practices. Globally, racing organisations may consider the findings of the present study helpful in their deliberations on the merits of continuing the practice of whipping tired horses in the name of sport. The study might also provide important data for stakeholders who demand that it continues

Dirac equation with coupling to 1/r singular vector potentials for all angular momenta

We consider the Dirac equation in 3+1 dimensions with spherical symmetry and coupling to 1/r singular vector potential. An approximate analytic solution for all angular momenta is obtained. The approximation is made for the 1/r orbital term in the Dirac equation itself not for the traditional and more singular 1/r^2 term in the resulting second order differential equation. Consequently, the validity of the solution is for a wider energy spectrum. As examples, we consider the Hulthen and Eckart potentials.Comment: 7 page

Türkiye’de bulunan yoğun bakımlarda sabun, kağıt havlu ve alkol bazlı el dezenfektanı yeterli mi?: Phokai çalışması sonuçları

Introduction: Hand hygiene is one of the most effective infection control measures to prevent the spread of healthcare-associated infections (HCAI). Water, soap, paper towel and hand disinfectant must be available and adequate in terms of effective hand hygiene. The adequacy of hand hygiene products or keeping water-soap and paper towel is still a problem for many developing countries like Turkey. In this multicenter study, we analyzed the adequacy in number and availability of hand hygiene products.Materials and Methods: This study was performed in all intensive care units (ICUs) of 41 hospitals (27 tertiary-care educational, 10 state and four private hospitals) from 22 cities located in seven geographical regions of Turkey. We analyzed water, soap, paper towel and alcohol-based hand disinfectant adequacy on four different days, two of which were in summer during the vacation time (August, 27th and 31st 2016) and two in autumn (October, 12th and 15th 2016).Results: The total number of ICUs and intensive care beds in 41 participating centers were 214 and 2357, respectively. Overall, there was no soap in 3-11% of sinks and no paper towel in 10-18% of sinks while there was no alcohol-based hand disinfectant in 1-4.7% of hand disinfectant units on the observation days. When we compared the number of sinks with soap and/or paper towel on weekdays vs. weekends, there was no significant difference in summer. However, on autumn weekdays, the number of sinks with soap and paper towel was significantly lower on weekend days (p<0.0001, p<0.0001) while the number of hand disinfectant units with alcohol-based disinfectant was significantly higher (p<0.0001).Conclusion: There should be adequate and accessible hand hygiene materials for effective hand hygiene. In this study, we found that soap and paper towels were inadequate on the observation days in 3-11% and 10-18% of units, respectively. Attention should be paid on soap and paper towel supply at weekends as well

Biocomposite films based on κ-carrageenan/locust bean gum blends and clays : physical and antimicrobial properties

The aims of this work were to evaluate the physical and antimicrobial properties of biodegradable films composed of mixtures of κ-carrageenan (κ-car) and locust bean gum (LBG) when organically modified clay Cloisite 30B (C30B) was dispersed in the biopolymer matrix. Film-forming solutions were prepared by adding C30B (ranging from 0 to 16 wt.%) into the κ-car/LBG solution (40/60 wt.%) with 0.3 % (w/v) of glycerol. Barrier properties (water vapour permeability, P vapour; CO2 and O2 permeabilities), mechanical properties (tensile strength, TS, and elongation-at-break, EB) and thermal stability of the resulting films were determined and related with the incorporation of C30B. Also, X-ray diffraction (XRD) was done in order to investigate the effect of C30B in film structure. Antimicrobial effects of these films against Listeria monocytogenes, Escherichia coli and Salmonella enterica were also evaluated. The increase of clay concentration causes a decrease of P vapour (from 5.34 × 10−11 to 3.19 × 10−11 g (m s Pa)−1) and an increase of the CO2 permeability (from 2.26 × 10−14 to 2.91 × 10−14 g (m s Pa)−1) and did not changed significantly the O2 permeability for films with 0 and 16 wt.% C30B, respectively. Films with 16 wt.% clay exhibited the highest values of TS (33.82 MPa) and EB (29.82 %). XRD patterns of the films indicated that a degree of exfoliation is attained depending on clay concentration. κ-car/LBG–C30B films exhibited an inhibitory effect only against L. monocytogenes. κ-car/LBG–C30B composite films are a promising alternative to synthetic films in order to improve the shelf life and safety of food products.J. T. Martins, A. I. Bourbon, A. C. Pinheiro and M. A. Cerqueira gratefully acknowledge the Fundacao para a Ciencia e Tecnologia (FCT, Portugal) for their fellowships (SFRH/BD/32566/2006, SFRH/BD/73178/2010, SFRH/BD/48120/2008 and SFRH/BPD/72753/2010, respectively), and B. W. S. Souza acknowledges the Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior (CAPES, Brazil)

Aggressive PDACs show hypomethylation of repetitive elements and the execution of an intrinsic IFN program linked to a ductal cell of origin

Pancreatic ductal adenocarcinoma (PDAC) is characterized by extensive desmoplasia, which challenges the molecular analyses of bulk tumor samples. Here we FACS-purified epithelial cells from human PDAC and normal pancreas and derived their genome-wide transcriptome and DNA methylome landscapes. Clustering based on DNA methylation revealed two distinct PDAC groups displaying different methylation patterns at regions encoding repeat elements. Methylation(low) tumors are characterized by higher expression of endogenous retroviral (ERV) transcripts and dsRNA sensors which leads to a cell intrinsic activation of an interferon signature (IFNsign). This results in a pro-tumorigenic microenvironment and poor patient outcome. Methylation(low)/IFNsign(high) and Methylation(high)/IFNsign(low) PDAC cells preserve lineage traits, respective of normal ductal or acinar pancreatic cells. Moreover, ductal-derived Kras(G12D)/Trp53(−/−) mouse PDACs show higher expression of IFNsign compared to acinar-derived counterparts. Collectively, our data point to two different origins and etiologies of human PDACs, with the aggressive Methylation(low)/IFNsign(high) subtype potentially targetable by agents blocking intrinsic IFN-signaling

Novel Textbook Outcomes following emergency laparotomy:Delphi exercise

Background: Textbook outcomes are composite outcome measures that reflect the ideal overall experience for patients. There are many of these in the elective surgery literature but no textbook outcomes have been proposed for patients following emergency laparotomy. The aim was to achieve international consensus amongst experts and patients for the best Textbook Outcomes for non-trauma and trauma emergency laparotomy. Methods: A modified Delphi exercise was undertaken with three planned rounds to achieve consensus regarding the best Textbook Outcomes based on the category, number and importance (Likert scale of 1–5) of individual outcome measures. There were separate questions for non-trauma and trauma. A patient engagement exercise was undertaken after round 2 to inform the final round. Results: A total of 337 participants from 53 countries participated in all three rounds of the exercise. The final Textbook Outcomes were divided into ‘early’ and ‘longer-term’. For non-trauma patients the proposed early Textbook Outcome was ‘Discharged from hospital without serious postoperative complications (Clavien–Dindo ≥ grade III; including intra-abdominal sepsis, organ failure, unplanned re-operation or death). For trauma patients it was ‘Discharged from hospital without unexpected transfusion after haemostasis, and no serious postoperative complications (adapted Clavien–Dindo for trauma ≥ grade III; including intra-abdominal sepsis, organ failure, unplanned re-operation on or death)’. The longer-term Textbook Outcome for both non-trauma and trauma was ‘Achieved the early Textbook Outcome, and restoration of baseline quality of life at 1 year’. Conclusion: Early and longer-term Textbook Outcomes have been agreed by an international consensus of experts for non-trauma and trauma emergency laparotomy. These now require clinical validation with patient data.</p

Innovated Expandable Office Table with Led Strips Imperative usage for Technology Students

This study presents an innovative, ergonomically designed office table specifically for technology students. Equipped with LED strips for optimal lighting, the table allows for expansion as needed, providing flexibility and efficient space utilization. The primary objective is to enhance the functionality, aesthetics, and ergonomic comfort of an innovative office table, making it more suited to the needs of tech-savvy students. The research methodology includes designing an ergonomic prototype, testing its functionality, and gathering feedback and satisfaction from a sample of technology students and instructors. To select the sample, the researchers used a convenience selection method, choosing participants based on their convenient accessibility and proximity to the researcher. The selection of participants was based on their convenient availability and close proximity to the researcher. The ergonomic design aims to improve posture, reduce back pain, and increase comfort during long study hours. Potential findings could suggest that this table not only enhances study conditions and improves space usage, but also significantly increases user comfort and productivity due to its ergonomic feature. In conclusion, this research, using convenience sampling, aims to provide a more conducive and ergonomically comfortable study environment for technology students, with significant implications for future office furniture design