Means of payment, the unbanked, and EFT '99

Electronic funds transfers ; Checks ; Social security

An LED-based Flasher System for VERITAS

We describe a flasher system designed for use in monitoring the gains of the photomultiplier tubes used in the VERITAS gamma-ray telescopes. This system uses blue light-emitting diodes (LEDs) so it can be operated at much higher rates than a traditional laser-based system. Calibration information can be obtained with better statistical precision with reduced loss of observing time. The LEDs are also much less expensive than a laser. The design features of the new system are presented, along with measurements made with a prototype mounted on one of the VERITAS telescopes.Comment: Accepted for publication in Nuclear Instruments and Methods in Physics Research

Analysing the limitations of deep learning for developmental robotics

Deep learning is a powerful approach to machine learning however its inherent disadvantages leave much to be desired in the pursuit of the perfect learning machine. This paper outlines the multiple disadvantages of deep learning and offers a view into the implications to solving these problems and how this would affect the state of the art not only in developmental learning but also in real world applications

Learning in Online Continuing Professional Development: An Institutionalist View on the Personal Learning Environment

The nature of institutions is an important question for the Personal Learning Environment (PLE). Whilst the PLE has tended to focus on what is considered to be “non-institutional” technology like social software, most online tools today have a corporate/institutional foundation. How should educators position themselves with learners who have to negotiate different institutional and discursive contexts – whether within corporate social software, formal education, work or the family? Drawing on previous work focusing on how learners maintain personal coherence in organising learning between different contexts, institutional theory is used to revise the model of the learner as a ‘viable system’, which focuses on the dynamics of transactions that learners make with different institutional entities. Data from an online Continuing Professional Development (CPD) course in acute cancer care is analysed to show how learner transactions indicate constraints bearing upon learners both from their professional context and from their formal educational study. The pattern of learner engagement suggests that the interaction of constraints creates the conditions to motivate in-depth contribution to the course forums.  This finding leads us to suggest a rethink of pedagogy within the PLE, and a broader consideration of institutional and other constraints in educational dynamics

Preterm infants have deficient monocyte and lymphocyte cytokine responses to Group B Streptococcus

Group B streptococcus GBS) is an important cause of early-and late-onset sepsis in the newborn. Preterm infants have markedly increased susceptibility and worse outcomes, but their immunological responses to GBS are poorly defined. We compared mononuclear cell and whole-blood cytokine responses to heat-killed GBS HKGBS) of preterm infants gestational age [GA], 26 to 33 weeks), term infants, and healthy adults. We investigated the kinetics and cell source of induced cytokines and quantified HKGBS phagocytosis. HKGBS-induced tumor necrosis factor TNF) and interleukin 6 (IL-6) secretion was significantly impaired in preterm infants compared to that in term infants and adults. These cytokines were predominantly monocytic in origin, and production was intrinsically linked to HKGBS phagocytosis. Very preterm infants GA, < 30 weeks) had fewer cytokine-producing monocytes, but nonopsonic phagocytosis ability was comparable to that for term infants and adults. Exogenous complement supplementation increased phagocytosis in all groups, as well as the proportion of preterm monocytes producing IL-6, but for very preterm infants, responses were still deficient. Similar defective preterm monocyte responses were observed in fresh whole cord blood stimulated with live GBS. Lymphocyte-associated cytokines were significantly deficient for both preterm and term infants compared to levels for adults. These findings indicate that a subset of preterm monocytes do not respond to GBS, a defect compounded by generalized weaker lymphocyte responses in newborns. Together these deficient responses may increase the susceptibility of preterm infants to GBS infection

The evidence for automated grading in diabetic retinopathy screening

Peer reviewedPostprin

Investigation of the current status of anticoagulant resistance in UK Norway rats by VKORC1 genotyping

Clarke, D.J., Prescott, C.V