Assessment of Structural Traits and Management Related to Dairy Herds in the Peri-urban Area of Bobo Dioulasso (South West of Burkina Faso)

To define mean herd size, structural traits, animal sourcing and use, management and aspects related to the milk production, 118 dairy herds, involved in a FAO dairy development project were studied. The mean herd size after allocation to clusters: Small (≤38 heads), Medium (>38, ≤61 heads) and Large (>61 heads) was 52.8±25.8, ranging from 7 to 134 heads of cattle. The following genotypes: Cross bred (CR) 58.8%, Zebu (ZB) 23.2% and Taurine cattle (TA) 18.0% which were not uniformly distributed neither across nor within herds were identified. Sex ratio was two thirds of females (70.6%), one third of males (28.1%) and a low proportion (1.3%) of castrated males. No mature TA males compared to 53.3% of the male ZB and 31.4% of the male CR, were indicated as potential sires. Investments in purchase of animals were higher in Small than in Medium and Large herds; of all purchased sires 53.8% were found in Small herds vs. 28.2% and 18.0% in Medium and Large. Herd property was equally distributed between single (56.8%) and multi property (43.2%). There was more manpower available per 100 cows in Small, being almost double and triple than in Medium and Large herds. Although milk extracted, was similar in all clusters averaging 2.4±0.5 litres/day/cow, milk off take rate, due to higher proportion of lactating cows, appeared higher in Small herds

GRB Observed by IBIS/PICsIT in the MeV Energy Range

We present the preliminary results of a systematic search for GRB and other transients in the publicly available data for the IBIS/PICsIT (0.2-10 MeV) detector on board INTEGRAL. Lightcurves in 2-8 energy bands with time resolution from 1 to 62.5 ms have been collected and an analysis of spectral and temporal characteristics has been performed. This is the nucleus of a forthcoming first catalog of GRB observed by PICsIT.Comment: 6 pages, 3 figures. Poster presented at COSPAR 2008. Advaces in Space Research, accepted for publicatio

Biology of bone sarcomas and new therapeutic developments

Bone sarcomas are tumours belonging to the family of mesenchymal tumours and constitute a highly heterogeneous tumour group. The three main bone sarcomas are osteosarcoma, Ewing sarcoma and chondrosarcoma each subdivided in diverse histological entities. They are clinically characterised by a relatively high morbidity and mortality, especially in children and adolescents. Although these tumours are histologically, molecularly and genetically heterogeneous, they share a common involvement of the local microenvironment in their pathogenesis. This review gives a brief overview of their specificities and summarises the main therapeutic advances in the field of bone sarcoma

Effect of dietary supplementation with insect fats on growth performance, digestive efficiency and health of rabbits

Background: The present work aimed at evaluating the effect of the dietary replacement of soybean oil (S) by two types of insect fats extracted from black soldier fly larvae (H, Hermetia illucens L.) and yellow mealworm larvae (T, Tenebrio molitor L.) on growth performance, nutrient digestibility, blood parameters, intestinal morphology and health of growing rabbits. Methods: At weaning, 200 crossbred rabbits (36 days old) were allotted to five dietary treatments (40 rabbits/group): a control diet (C) containing 1.5% of soybean oil and four experimental diets where soybean oil was partially (50%) or totally (100%) substituted by H (H50 and H100) or T (T50 and T100) fats. Total tract digestibility was evaluated on 12 rabbits per treatment. The growth trial lasted 41 d and, at slaughtering (78 days old), blood samples were collected from 15 rabbits per treatment, morphometric analyses were performed on duodenum, jejunum and ileum mucosa, and samples of liver, spleen and kidney were submitted to histological evaluation. Results: No difference was observed between the control and the experimental groups fed insect fats in terms of performance, morbidity, mortality and blood variables. The addition of H and T fats did not influence apparent digestibility coefficients of dry matter, protein, ether extract, fibre fractions and gross energy. Gut morphometric indices and organ histopathology were not affected by dietary inclusion of H and T fats. Conclusions: H and T fats are suitable sources of lipid in rabbit diets to replace soybean oil without any detrimental effect on growth performance, apparent digestibility, gut mucosa traits and health

La lipomatosi congenita infiltrante del volto. Caso Clinico

Congenital infiltrating lipomatosis of the face, first described by Beck in 1836, is a rare condition of unknown etiology, characterized by widespread infiltration of mature fat cells in the context of tissues softening of the face, with associated consequent bone deformities. It is presented as an isolated or associated condition hemimegalencephaly and neurocutaneous syndromes. We describe the case of a 10-year-old patient with known lipomatosis congenital of the face, arrived at our structure for follow up with Computed Tomography (CT) and Resonance Magnetic (RM) .

Tcf7l2 plays pleiotropic roles in the control of glucose homeostasis, pancreas morphology, vascularization and regeneration

Type 2 diabetes (T2D) is a disease characterized by impaired insulin secretion. The Wnt signaling transcription factor Tcf7l2 is to date the T2D-associated gene with the largest effect on disease susceptibility. However, the mechanisms by which TCF7L2 variants affect insulin release from \u3b2-cells are not yet fully understood. By taking advantage of a tcf7l2 zebrafish mutant line, we first show that these animals are characterized by hyperglycemia and impaired islet development. Moreover, we demonstrate that the zebrafish tcf7l2 gene is highly expressed in the exocrine pancreas, suggesting potential bystander effects on \u3b2-cell growth, differentiation and regeneration. Finally, we describe a peculiar vascular phenotype in tcf7l2 mutant larvae, characterized by significant reduction in the average number and diameter of pancreatic islet capillaries. Overall, the zebrafish Tcf7l2 mutant, characterized by hyperglycemia, pancreatic and vascular defects, and reduced regeneration proves to be a suitable model to study the mechanism of action and the pleiotropic effects of Tcf7l2, the most relevant T2D GWAS hit in human populations

Estudo da infestação artificial de carrapatos Riphicephalus (Boophilus) microplus em fêmeas bovinas Nelore, Angus x Nelore e Senepol x Nelore.

A resistência de bovinos de diferentes grupos genéticos ao carrapato Riphicephalus (Boophilus) microplus foi avaliada por meio de infestação artificial, utilizando-se 68 fêmeas dos grupos genéticos Nelore (NE, 25), Angus x Nelore (AN, 19) e Senepol x Nelore (SN, 25), com média de idade de 15,16 meses. Esses animais, mantidos sem tratamento carrapaticida em pasto de capim-tanzânia, foram infestados quatro vezes com 20.000 larvas de carrapato, com intervalos de quatorze dias, e do 19o ao 23o dia após cada infestação foram realizadas contagens de teleóginas semi-ingurgitadas do lado esquerdo do animal. Os dados foram analisados em termos de percentagem de retorno (PRij), ou seja, percentagem de carrapatos contados em relação ao total infestado, após transformação para PRij 1/4, e também pelo número de carrapatos contados (Cij) em cada animal i e infestação j, após transformação para CTij = log(Cij + 1), utilizando-se o método dos quadrados mínimos com um modelo que incluiu os efeitos de grupo genético (GG), animal dentro de GG (erro a), infestação (I) e GG x I. Não houve interação GG x I e os resultados indicaram maior percentagem de retorno e maior número de carrapatos contados para os animais AN, seguidos dos SN e por último dos NE. As médias da percentagem de retorno transformada (PRij 1/4) para os diferentes grupos genéticos foram iguais a 0,490 ± 0,015 (NE), 0,989 ± 0,018 (AN) e 0,616 ± 0,015 (SN) e as médias do número de carrapatos contados transformado (CTij) foram iguais a 1,558 ± 0,058 (NE), 3,760 ± 0,066 (AN) e 2,135 ± 0,058 (SN)