The increasing frequency of terms denoting political extremism in U.S. and U.K. news media

The term political extremism is commonly used to refer to political attitudes considered to be outside the ideological mainstream. This study leverages computational content analysis of big data to longitudinally examine (1970–2019) the prevalence of terms denoting far-right and far-left political extremism in more than 30 million written news and opinion articles from 54 news media outlets popular in the United States and the United Kingdom. We find that the usage of terms denoting right and left political extremism has been increasing across news media outlets in both countries. This trend is particularly stark for far-right-denoting terms, which have been growing in prevalence since at least 2008. Most U.S. and U.K. news media outlets tend to use far-right-denoting terms substantially more often than they use far-left-denoting terms. The rising prevalence in news media of terms denoting political extremism is strongly correlated with similar growing usage of terms denoting prejudice and social justice discourse

Effect of remote ischaemic conditioning on clinical outcomes in patients with acute myocardial infarction (CONDI-2/ERIC-PPCI): a single-blind randomised controlled trial.

BACKGROUND: Remote ischaemic conditioning with transient ischaemia and reperfusion applied to the arm has been shown to reduce myocardial infarct size in patients with ST-elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PPCI). We investigated whether remote ischaemic conditioning could reduce the incidence of cardiac death and hospitalisation for heart failure at 12 months. METHODS: We did an international investigator-initiated, prospective, single-blind, randomised controlled trial (CONDI-2/ERIC-PPCI) at 33 centres across the UK, Denmark, Spain, and Serbia. Patients (age >18 years) with suspected STEMI and who were eligible for PPCI were randomly allocated (1:1, stratified by centre with a permuted block method) to receive standard treatment (including a sham simulated remote ischaemic conditioning intervention at UK sites only) or remote ischaemic conditioning treatment (intermittent ischaemia and reperfusion applied to the arm through four cycles of 5-min inflation and 5-min deflation of an automated cuff device) before PPCI. Investigators responsible for data collection and outcome assessment were masked to treatment allocation. The primary combined endpoint was cardiac death or hospitalisation for heart failure at 12 months in the intention-to-treat population. This trial is registered with ClinicalTrials.gov (NCT02342522) and is completed. FINDINGS: Between Nov 6, 2013, and March 31, 2018, 5401 patients were randomly allocated to either the control group (n=2701) or the remote ischaemic conditioning group (n=2700). After exclusion of patients upon hospital arrival or loss to follow-up, 2569 patients in the control group and 2546 in the intervention group were included in the intention-to-treat analysis. At 12 months post-PPCI, the Kaplan-Meier-estimated frequencies of cardiac death or hospitalisation for heart failure (the primary endpoint) were 220 (8·6%) patients in the control group and 239 (9·4%) in the remote ischaemic conditioning group (hazard ratio 1·10 [95% CI 0·91-1·32], p=0·32 for intervention versus control). No important unexpected adverse events or side effects of remote ischaemic conditioning were observed. INTERPRETATION: Remote ischaemic conditioning does not improve clinical outcomes (cardiac death or hospitalisation for heart failure) at 12 months in patients with STEMI undergoing PPCI. FUNDING: British Heart Foundation, University College London Hospitals/University College London Biomedical Research Centre, Danish Innovation Foundation, Novo Nordisk Foundation, TrygFonden

Evolving Hierarchical Temporal Memory-Based Trading Models

We explore the possibility of using the genetic algorithm to optimize trading models based on the Hierarchical Temporal Memory (HTM) machine learning technology. Technical indicators, derived from intraday tick data for the E-mini S&P 500 futures market (ES), were used as feature vectors to the HTM models. All models were configured as binary classifiers, using a simple buy-and-hold trading strategy, and followed a supervised training scheme. The data set was partitioned into multiple folds to enable a modified cross validation scheme. Artificial Neural Networks (ANNs) were used to benchmark HTM performance. The results show that the genetic algorithm succeeded in finding predictive models with good performance and generalization ability. The HTM models outperformed the neural network models on the chosen data set and both technologies yielded profitable results with above average accuracy

Fixed Frame Temporal Pooling

Abstract. Applications of unsupervised learning techniques to action recognition have proved highly competitive in comparison to supervised and hand-crafted approaches, despite not being designed to handle image processing problems. Many of these techniques are either based on biological models of cognition or have responses that correlate to those observed in biological systems. In this study we apply (for the first time) an adaptation of the latest hierarchical temporal memory (HTM) cortical learning algorithms (CLAs) to the problem of action recognition. These HTM algorithms are both unsupervised and represent one of the most complete high-level syntheses available of the current neuroscientific understanding of the functioning of neocortex. Specifically, we extend the latest HTM work on augmented spatial pooling, to produce a fixed frame temporal pooler (FFTP). This pooler is evaluated on the well-known KTH action recognition data set and in comparison with the best performing unsupervised learning algorithm for bag-of-features classification in the area: independent subspace analysis (ISA). Our results show FFTP comes within 2 % of ISA’s performance and outperforms other comparable techniques on this data set. We take these results to be promising, given the preliminary nature of the research and that the FFTP algorithm is only a partial implementation of the proposed HTM architecture.