Azha. Valliyappa's Songs in the Point of View of Dravidian Ideology

Childhood is the foundation of everyone's life. It is quite necessary that children are guided properly in this phase. The thoughts sown in the minds of children help them to lead their life in a great way. So, these good thoughts should be taught to them through subject matters that interest them. Children's Literature does the exact same thing. Children's songs that are composed with simplicity and musicality attract them and amuse them greatly. Children's Poet Azha. Valliyappa has contributed many poems, short stories, dramas and novels to Children's Literature. Children are his exclusive audience. Writing for children is an art. Whatever a child listens to, reads and writes are registered in her mind and it has a long-lasting impression because there are no worries for children. Their minds are as fresh as a clean slate and whatever is written on it is well learnt by them. What they learn help them grow into matured people. A sword meant for warfare can't be used to sharpen a pencil. Similarly, any advice that is forcefully instructed to anyone can never bring fruitful results. Azha. Valliyappa has clearly understood it and he has given children many rational thoughts in a language that can be easily understood by them

Validation of multi-machine and single-machine equivalent models for wind farm transient stability studies

Stability study of power system with wind farm is challenging task due to collection of system data, computation burden in case of system order and long simulation time. An aggregated representation of fixed speed wind turbine generator (WTG) is proposed for an actual wind farm which is a part of the Indian utility system. The stability study of actual system and equivalent system are simulated in MATLAB software package. Multi-machine and single-machine equivalent wind farm models are developed based on simple aggregation technique. The transient stability responses of these two equivalent wind farm models that are compared with actual wind farm system at point of common coupling (PCC). The two equivalent wind farm models response provides a satisfactory accuracy with actual system response for the three phase fault and varying wind speed. Also equivalent wind farm model responses are validated with actual system response for different dynamic conditions.Â

Antimicrobial activity study of ethanolic extract of Alternanthera sessilis linn. aerial parts

The ethanolic extract of Alternanthera sessilis Linn. was evaluated for antimicrobial activity study against medically important gram-positive bacteria such as Staphylococcus aureus, Bacillus subtilis, Bacillus polymexia & Streotococcus faecalis, gram negative bacteria such as Pseudomonas aerugenosa, Salmonella typhii, Shigella dysenteriae & Escherichia coli and fungi like Penicillum notatum, Aspergillus niger & Candida albicans. The in-vitro antimicrobial activity, minimum inhibitory concentration (MIC) of ethanolic extract was performed by broth dilution method and the zone of inhibition was studied by agar disc diffusion method at concentrations of 2, 5 and 10mg/ml in DMSO. Ciprofloxacin (5µg/ml) and Cotrimazole (25µg/ml) were used as reference control for the antibacterial and antifungal studies respectively. The results of MIC study revealed the antimicrobial activity of the extract against the tested strains of microorganisms between concentration range of 50 and 400 µg/ml. The results of zone of inhibition study revealed concentration dependant nature of the extract with better effectiveness against gram-positive bacteria than gram-negative bacteria. The present study indicates the potential usefulness of Alternanthera sessilis Linn. aerial parts in the treatment of various pathogenic diseases as mentioned in the ayurvedic literature

Structural, Optical and Electrical Properties of Green Synthesis CdO Nanoparticles and Its Ag/CdO/P-Si Junction Diode Fabricated Via JNS Pyrolysis Techniqu

CdO nanoparticle is synthesized using green tea extract as solvent by microwave irradiation method. Its crystalline structure is confirmed by the well define peaks of powder XRD study. The surface morphology is analyzed by SEM and TEM spectrograph. The percentage composition of cadmium present in the synthesized material is confirmed by EDS study also presence of various functional groups is analysis using FTIR spectrum. The band gap energy of composed material is calculated with the help of cut off peak of diffused reflectance spectrum of UV study. The thermal conductance of the substance is increasing with increasing the temperature. The good rectifying character of CdO is explained with the help of I-V character study

The oxidation status of Mic19 regulates MICOS assembly.

The function of mitochondria depends on the proper organization of mitochondrial membranes. The morphology of the inner membrane is regulated by the recently identified mitochondrial contact site and cristae organizing system (MICOS) complex. MICOS mutants exhibit alterations in crista formation, leading to mitochondrial dysfunction. However, the mechanisms that underlie MICOS regulation remain poorly understood. MIC19, a peripheral protein of the inner membrane and component of the MICOS complex, was previously reported to be required for the proper function of MICOS in maintaining the architecture of the inner membrane. Here, we show that human and yeast MIC19 proteins undergo oxidation in mitochondria and require the mitochondrial intermembrane space assembly (MIA) pathway, which couples the oxidation and import of mitochondrial intermembrane space proteins for mitochondrial localization. Detailed analyses identified yeast Mic19 in two different redox forms. The form that contains an intramolecular disulfide bond is bound to Mic60 of the MICOS complex. Mic19 oxidation is not essential for its integration into the MICOS complex but plays a role in MICOS assembly and the maintenance of proper inner membrane morphology. These findings suggest that Mic19 is a redox-dependent regulator of MICOS function

Fly Ash Particle Reinforced And Mechanical Properties Of AL6061 Graphite B4C Composites

Fly ash particle reinforced with aluminium alloy composite materials used for various industrial applications like automobile, aerospace, aircrafts, substrate in electronics, turbine blades, brake pads, golf clubs and it is also used in home products. Metal matrix composites (MMCs) are increased mechanical properties like strength, yield strength, hardness, impact strength and to improve fracture toughness when compared to unreinforced alloys. The main aim is to fabrication of Al6061/Fly ash, Boron carbide, Graphite, and also Magnesium metal matrix composite by using stir casting process and also study the mechanical properties of the fabricated composite material. Fly ashes with aluminium, composite materials are good mechanical and physical properties for very high temperature, resistant to wear and lowest weight applications. Aluminium composite preparing from liquid phase reaction present a unique microstructure. The each phase is a continuous network penetrated by the network of the other constituent. It is an increased composites containing lowest cost expensive and lowest density reinforcements. The fly is very less expensive and very low density reinforced in solid waste by the product during combustion of coal in thermal power plants. Hence, fly ashes with aluminium composites reinforcement are to overcome the cost expensive for wide applications in automotive ancillaries, aircrafts, turbine blades and also engine applications. In future we add the graphite, boron carbide and magnesium with Al6061 & Fly ash to produce other metal matrix composites.Keywords- Fly ash; Wear resistant; Metal–matrix composites (MMCs); Casting; Particle-reinforcement

Design and Analysis of Turbocharger Impeller in Diesel Engine

The main goal of this research is to be design the turbine and compressor impeller of a turbocharger for a diesel engine. It is to increase power and efficiency of a turbocharger. It is to usage of new material is required for an investigation. The existing work turbine and compressor impeller has been designed with different materials. The investigation has been done by using ANSYS and CATIA software. The turbine and compressor impeller modeling has been done by using CATIA software. The variation of stresses, strains and deformation profile of the turbine and compressor impeller has been determined by using ANSYS software. The identifying the accurate or exactdesign features, the extended service life and long term stability has been assured. A structural analysis is used to investigate the stresses, strains and displacements of the turbine and compressor impeller. A modal analysis is used to investigate the frequency and deflection of the turbine and compressor impeller. A thermal analysis is used to investigate the total heat flux and direction heat flux. The turbine and compressor impeller of a turbocharger will be recommend based on the better material results

Pancreatic Lipase inhibition assay of various extracts of leaves of Murraya Koenigii in southern areas of Goa

The objective of the study was to assess the lipase inhibitory activities of chloroformic, methanolic and aqueous extracts from the commonly available Murraya koenigii (L.) Spreng leaves(Rutaceae) in southern villages of Goa, for potential use in the treatment of obesity. Extracs of the leaves of this plant were evaluated for lipase inhibitory activity using porcine pancreatic lipase (PPL: triacylglycerol lipase) and p-nitrophenyl butyrate in an in vitro assay. Among the three extracts screened, chloroformic extract exhibited the highest pancreatic lipase inhibitory activity of 53.42%, followed by methanolic extract (51.88%) and aqueous extract (36.42%), respectively. Chloroformic extract has not been screened for its pancreatic lipase inhibition assay. All the Crude extracts of leaves of Murraya koenigii (L.) Spreng leaves (Rutaceae) have potential as pancreatic lipase inhibitory agents. . Chloroformic extract was found to be most effective and hence can be used as a potent anti-obesity agent to combat hyperlipidemia

Obesity and prolactin in various populations

Association of Obesity with altered levels of serum prolactin (PRL), a marker of stress is well documented. The objective of this systematic review and meta-analysis was to estimate the association between obesity and PRL according to sex, ethnicity and age. PubMed, Web of Science (WoS) & EBSCO database were searched from the 5th to 20th of October 2018. Two reviewers independently extracted data from 12 cross sectional studies that used body mass index (BMI), waist circumference (WC) or waist-to-hip ratio (WHR) as measures of obesity and aggregated using the random-effect model. The correlation (r) for BMI and PRL was -0.231; 95% confidence interval (CI) = -0.392 to -0.055) in adults and (r = -0.500; 95% CI = -0.622 to -0.354) in children. In adults, r for BMI and PRL was greater in women than men by -0.127 (95% CI = -0.178 to -0.05) and greater in European populations r=0.156 (95% CI = -0132 to -0.079) than Middle Eastern populations r = -0.655(95% CI = -0.880 to 0.191). Obesity is associated with decreased levels of PRL, and the association is greater among women and Europeans. The emergence of difference between different genders was observed only in adulthood

Differential item functioning for items in Berger's HIV Stigma Scale: an analysis of cohorts from the Indian, Swedish, and US contexts

PURPOSE: To examine whether items in Berger's HIV Stigma Scale function differently with persons of different age, gender, and cultural backgrounds. METHODS: Secondary data from cohorts, collected in South India (n = 250), Sweden (n = 193), and the US (n = 603) were reanalyzed to evaluate DIF within, between, and across these cohorts. All participants had answered the revised version of the HIV stigma scale consisting of 32 items forming the subscales Personalized stigma, Disclosure concerns, Concerns about public attitudes, and Negative self-image. Differential Item Functioning (DIF) for these items was assessed using hybrid ordinal regression-IRT technique. When DIF was detected, the cumulative impact of DIF on individual subscale scores was evaluated. RESULTS: DIF was detected for 9 items within, between, or across cohorts, but the DIF was negligible in general. Detected DIF between the Swedish and Indian cohorts had a cumulative salient impact on individual scores for the subscale Disclosure Concerns; Disclosure concerns were overestimated in the Swedish cohort and both over- and underestimated in the Indian cohort. CONCLUSIONS: The items in the 32-item version of the HIV stigma scale did not seem to be particularly prone to present DIF. The DIF between the Indian and Swedish cohort for items in the subscale Disclosure Concerns could, however, result in both type I and type II errors if scores should be compared between the Indian and Swedish cohort