187 research outputs found
Electron interferometry with nano-gratings
We present an electron interferometer based on near-field diffraction from
two nanostructure gratings. Lau fringes are observed with an imaging detector,
and revivals in the fringe visibility occur as the separation between gratings
is increased from 0 to 3 mm. This verifies that electron beams diffracted by
nanostructures remain coherent after propagating farther than the Talbot length
= 1.2 mm, and hence is a proof of principle for the
function of a Talbot-Lau interferometer for electrons. Distorted fringes due to
a phase object demonstrates an application for this new type of electron
interferometer.Comment: 4 pgs, 6 figure
An electron Talbot interferometer
The Talbot effect, in which a wave imprinted with transverse periodicity
reconstructs itself at regular intervals, is a diffraction phenomenon that
occurs in many physical systems. Here we present the first observation of the
Talbot effect for electron de Broglie waves behind a nanofabricated
transmission grating. This was thought to be difficult because of Coulomb
interactions between electrons and nanostructure gratings, yet we were able to
map out the entire near-field interference pattern, the "Talbot carpet", behind
a grating. We did this using a Talbot interferometer, in which Talbot
interference fringes from one grating are moire'-filtered by a 2nd grating.
This arrangement has served for optical, X-ray, and atom interferometry, but
never before for electrons. Talbot interferometers are particularly sensitive
to distortions of the incident wavefronts, and to illustrate this we used our
Talbot interferometer to measure the wavefront curvature of a weakly focused
electron beam. Here we report how this wavefront curvature demagnified the
Talbot revivals, and we discuss applications for electron Talbot
interferometers.Comment: 5 pages, 5 figures, updated version with abstrac
Analysis of the F2LR3 (PAR4) single nucleotide polymorphism (rs773902) in an Indigenous Australian population
The F2RL3 gene encoding protease activated receptor 4 (PAR4) contains a single nucleotide variant, rs773902, that is functional. The resulting PAR4 variants, Thr120, and Ala120, are known to differently affect platelet reactivity to thrombin. Significant population differences in the frequency of the allele indicate it may be an important determinant in the ethnic differences that exist in thrombosis and hemostasis, and for patient outcomes to PAR antagonist anti-platelet therapies. Here we determined the frequency of rs773902 in an Indigenous Australian group comprising 467 individuals from the Tiwi Islands. These people experience high rates of renal disease that may be related to platelet and PAR4 function and are potential recipients of PAR-antagonist treatments. The rs773902 minor allele frequency (Thr120) in the Tiwi Islanders was 0.32, which is similar to European and Asian groups and substantially lower than Melanesians and some African groups. Logistic regression and allele distortion testing revealed no significant associations between the variant and several markers of renal function, as well as blood glucose and blood pressure. These findings suggest that rs773902 is not an important determinant for renal disease in this Indigenous Australian group. However, the relationships between rs773902 genotype and platelet and drug responsiveness in the Tiwi, and the allele frequency in other Indigenous Australian groups should be evaluated
Letter of Intent: Muonium R&D/Physics Program at the MTA
With the planned turn-on of the PIP-II 800 MeV superconducting proton linac,
Fermilab will potentially become the world's best laboratory at which to carry
out fundamental muon measurements, sensitive searches for symmetry violation,
and precision tests of theory. In preparation, we propose to develop the
techniques that will be needed. An R&D and physics program is proposed at the
Fermilab MeV Test Area to use the existing 400 MeV Linac to demonstrate the
efficient production of a slow muonium beam using stopped in a
~100-m-thick layer of superfluid helium, and to use that beam to measure
muonium gravity.Comment: 3 pages, submitted to Fermila
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Seed Treatments: A New Option for Integrated Pest Management of Potato Leafroll Virus, Aphids, and Colorado Potato Beetle
Synthesizing skyrmion bound pairs in Fe-Gd thin films
We show that properly engineered amorphous Fe-Gd alloy thin films with perpendicular magnetic anisotropy exhibit bound pairs of like-polarity, opposite helicity skyrmions at room temperature. Magnetic mirror symmetry planes present in the stripe phase, instead of chiral exchange, determine the internal skyrmion structure and the net achirality of the skyrmion phase. Our study shows that stripe domain engineering in amorphous alloy thin films may enable the creation of skyrmion phases with technologically desirable properties
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Changes in green peach aphid population dynamics and potato leafroll virus suppression strategies
RNA profiling in host-pathogen interactions
The development of novel anti-bacterial treatment strategies will be aided by an increased understanding of the interactions that take place between bacteria and host cells during infection. Global expression profiling using microarray technologies can help to describe and define the mechanisms required by bacterial pathogens to cause disease and the host responses required to defeat bacterial infection
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