Dark Matter Halo Profiles in Scale-Free Cosmologies

We explore the dependence of the central logarithmic slope of dark matter halo density profiles $\alpha$ on the spectral index $n$ of the linear matter power spectrum $P(k)$ using cosmological $N$-body simulations of scale-free models (i.e. $P(k) \propto k^n$). For each of our simulations we identify samples of well resolved haloes in dynamical equilibrium and we analyse their mass profiles. By parameterising the mass profile using a ``generalised'' Navarro, Frenk & White profile in which the central logarithmic slope $\alpha$ is allowed to vary while preserving the $r^{-3}$ asymptotic form at large radii, we obtain preferred central slopes for haloes in each of our models. There is a strong correlation between $\alpha$ and $n$, such that $\alpha$ becomes shallower as $n$ becomes steeper. However, if we normalise our mass profiles by $r_{-2}$, the radius at which the logarithmic slope of the density profile is -2, we find that these differences are no longer present. We conclude that there is no evidence for convergence to a unique central asymptotic slope, at least on the scales that we can resolve.Comment: 9 pages, 4 figures. Accepted for publication in MNRA

How do dwarf galaxies acquire their mass & when do they form their stars?

We apply a simple, one-equation, galaxy formation model on top of the halos and subhalos of a high-resolution dark matter cosmological simulation to study how dwarf galaxies acquire their mass and, for better mass resolution, on over 10^5 halo merger trees, to predict when they form their stars. With the first approach, we show that the large majority of galaxies within group- and cluster-mass halos have acquired the bulk of their stellar mass through gas accretion and not via galaxy mergers. We deduce that most dwarf ellipticals are not built up by galaxy mergers. With the second approach, we constrain the star formation histories of dwarfs by requiring that star formation must occur within halos of a minimum circular velocity set by the evolution of the temperature of the IGM, starting before the epoch of reionization. We qualitatively reproduce the downsizing trend of greater ages at greater masses and predict an upsizing trend of greater ages as one proceeds to masses lower than m_crit. We find that the fraction of galaxies with very young stellar populations (more than half the mass formed within the last 1.5 Gyr) is a function of present-day mass in stars and cold gas, which peaks at 0.5% at m_crit=10^6-8 M_Sun, corresponding to blue compact dwarfs such as I Zw 18. We predict that the baryonic mass function of galaxies should not show a maximum at masses above 10^5.5, M_Sun, and we speculate on the nature of the lowest mass galaxies.Comment: 6 pages, to appear in "A Universe of Dwarf Galaxies: Observations, Theories, Simulations", ed. M. Koleva, P. Prugniel & I. Vauglin, EAS Series (Paris: EDP

The Effects of X-Ray Feedback from AGN on Host Galaxy Evolution

Hydrodynamic simulations of galaxies with active galactic nuclei (AGN) have typically employed feedback that is purely local: i.e., an injection of energy to the immediate neighborhood of the black hole. We perform GADGET-2 simulations of massive elliptical galaxies with an additional feedback component: an observationally calibrated X-ray radiation field which emanates from the black hole and heats gas out to large radii from the galaxy center. We find that including the heating and radiation pressure associated with this X-ray flux in our simulations enhances the effects which are commonly reported from AGN feedback. This new feedback model is twice as effective as traditional feedback at suppressing star formation, produces 3 times less star formation in the last 6 Gyr, and modestly lowers the final BH mass (30%). It is also significantly more effective than an X-ray background in reducing the number of satellite galaxies.Comment: 9 emulateapj pages, 8 figures; accepted to Ap

Bound and unbound substructures in Galaxy-scale Dark Matter haloes

We analyse the coarse-grained phase-space structure of the six Galaxy-scale dark matter haloes of the Aquarius Project using a state-of-the-art 6D substructure finder. Within r_50, we find that about 35% of the mass is in identifiable substructures, predominantly tidal streams, but including about 14% in self-bound subhaloes. The slope of the differential substructure mass function is close to -2, which should be compared to around -1.9 for the population of self-bound subhaloes. Near r_50 about 60% of the mass is in substructures, with about 30% in self-bound subhaloes. The inner 35 kpc of the highest resolution simulation has only 0.5% of its mass in self-bound subhaloes, but 3.3% in detected substructure, again primarily tidal streams. The densest tidal streams near the solar position have a 3-D mass density about 1% of the local mean, and populate the high velocity tail of the velocity distribution.Comment: Submitted to MNRAS on 12/10/2010, 11 pages, 10 figure

Gene Transfer of Engineered Calmodulin Alleviates Ventricular Arrhythmias in a Calsequestrin-Associated Mouse Model of Catecholaminergic Polymorphic Ventricular Tachycardia

Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a familial arrhythmogenic syndrome characterized by sudden death. There are several genetic forms of CPVT associated with mutations in genes encoding the cardiac ryanodine receptor (RyR2) and its auxiliary proteins including calsequestrin (CASQ2) and calmodulin (CaM). It has been suggested that impairment of the ability of RyR2 to stay closed (ie, refractory) during diastole may be a common mechanism for these diseases. Here, we explore the possibility of engineering CaM variants that normalize abbreviated RyR2 refractoriness for subsequent viral-mediated delivery to alleviate arrhythmias in non-CaM-related CPVT

Initial Characterization of CASQ1/CASQ2 Knockout (double CASQ-Null) Mice

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Automated detection of filaments in the large scale structure of the universe

We present a new method to identify large scale filaments and apply it to a cosmological simulation. Using positions of haloes above a given mass as node tracers, we look for filaments between them using the positions and masses of all the remaining dark-matter haloes. In order to detect a filament, the first step consists in the construction of a backbone linking two nodes, which is given by a skeleton-like path connecting the highest local dark matter (DM) density traced by non-node haloes. The filament quality is defined by a density and gap parameters characterising its skeleton, and filament members are selected by their binding energy in the plane perpendicular to the filament. This membership condition is associated to characteristic orbital times; however if one assumes a fixed orbital timescale for all the filaments, the resulting filament properties show only marginal changes, indicating that the use of dynamical information is not critical for the method. We test the method in the simulation using massive haloes($M>10^{14}$h$^{-1}M_{\odot}$) as filament nodes. The main properties of the resulting high-quality filaments (which corresponds to $\simeq33$ of the detected filaments) are, i) their lengths cover a wide range of values of up to $150$h$^{-1}$Mpc, but are mostly concentrated below 50h$^{-1}$Mpc; ii) their distribution of thickness peaks at $d=3.0$h$^{-1}$Mpc and increases slightly with the filament length; iii) their nodes are connected on average to $1.87\pm0.18$ filaments for $\simeq 10^{14.1}M_{\odot}$ nodes; this number increases with the node mass to $\simeq 2.49\pm0.28$ filaments for $\simeq 10^{14.9}M_{\odot}$ nodes.Comment: 17 pages, 13 figures, MNRAS Accepte

N-body simulations with generic non-Gaussian initial conditions I: Power Spectrum and halo mass function

We address the issue of setting up generic non-Gaussian initial conditions for N-body simulations. We consider inflationary-motivated primordial non-Gaussianity where the perturbations in the Bardeen potential are given by a dominant Gaussian part plus a non-Gaussian part specified by its bispectrum. The approach we explore here is suitable for any bispectrum, i.e. it does not have to be of the so-called separable or factorizable form. The procedure of generating a non-Gaussian field with a given bispectrum (and a given power spectrum for the Gaussian component) is not univocal, and care must be taken so that higher-order corrections do not leave a too large signature on the power spectrum. This is so far a limiting factor of our approach. We then run N-body simulations for the most popular inflationary-motivated non-Gaussian shapes. The halo mass function and the non-linear power spectrum agree with theoretical analytical approximations proposed in the literature, even if they were so far developed and tested only for a particular shape (the local one). We plan to make the simulations outputs available to the community via the non-Gaussian simulations comparison project web site http://icc.ub.edu/~liciaverde/NGSCP.html.Comment: 23 pages, 10 figure