Tunneling Splittings in Mn12-Acetate Single Crystals

A Landau-Zener multi-crossing method has been used to investigate the tunnel splittings in high quality Mn$_{12}$-acetate single crystals in the pure quantum relaxation regime and for fields applied parallel to the magnetic easy axis. With this method several individual tunneling resonances have been studied over a broad range of time scales. The relaxation is found to be non-exponential and a distribution of tunnel splittings is inferred from the data. The distributions suggest that the inhomogeneity in the tunneling rates is due to disorder that produces a non-zero mean value of the average transverse anisotropy, such as in a solvent disorder model. Further, the effect of intermolecular dipolar interaction on the magnetic relaxation has been studied.Comment: Europhysics Letters (in press). 7 pages, including 3 figure

Anomalous Hall conductivity control in Mn3_3NiN antiperovskite by epitaxial strain along the kagome plane

Antiferromagnetic manganese-based nitride antiperovskites, such as Mn$_3$NiN, hold a triangular frustrated magnetic ordering over their kagome lattice formed by the Mn atoms along the (111)-plane. As such, frustration imposes a non-trivial interplay between the symmetric and asymmetric magnetic interactions, which can only reach equilibrium in a noncollinear magnetic configuration. Consequently, the associated electronic interactions and their possible tuning by external constraints, such as applied epitaxial strain, play a crucial role in defining the microscopic and macroscopic properties of such topological condensed matter systems. Thus, in the present work, we explored and explained the effect of the epitaxial strain imposed within the (111)-plane, in which the magnetic and crystallographic symmetry operations are kept fixed, and only the magnitude of the ionic and electronic interactions are tuned. We found a linear shifting in the energy of the band structure and a linear increase/decrease of the available states near the Fermi level with the applied strain. Concretely, the compression strain reduces the Mn-Mn distances in the (111) kagome plane but linearly increases the separation between the stacked kagome lattices and the available states near the Fermi level. Despite the linear controlling of the available states across the Fermi energy, the anomalous Hall conductivity shows a non-linear behavior where the $\sigma_{111}$ conductivity nearly vanishes for tensile strain. On the other hand, $\sigma_{111}$ fetches a maximum increase of 26\% about the unstrained structure for a compression value close to $-$1.5\%.This behavior found an explanation in the non-divergent Berry curvature within the kagome plane, which is increased for constraining but significantly reduced for expansion strain values..

A cosmological dust model with extended f(chi) gravity

Introducing a fundamental constant of nature with dimensions of acceleration into the theory of gravity makes it possible to extend gravity in a very consistent manner. At the non-relativistic level a MOND-like theory with a modification in the force sector is obtained, which is the limit of a very general metric relativistic theory of gravity. Since the mass and length scales involved in the dynamics of the whole universe require small accelerations of the order of Milgrom's acceleration constant a_0, it turns out that the relativistic theory of gravity can be used to explain the expansion of the universe. In this work it is explained how to use that relativistic theory of gravity in such a way that the overall large-scale dynamics of the universe can be treated in a pure metric approach without the need to introduce dark matter and/or dark energy components.Comment: 7 pages, 1 figure. Accepted for publication in the European Physical Journal

A first--order irreversible thermodynamic approach to a simple energy converter

Several authors have shown that dissipative thermal cycle models based on Finite-Time Thermodynamics exhibit loop-shaped curves of power output versus efficiency, such as it occurs with actual dissipative thermal engines. Within the context of First-Order Irreversible Thermodynamics (FOIT), in this work we show that for an energy converter consisting of two coupled fluxes it is also possible to find loop-shaped curves of both power output and the so-called ecological function against efficiency. In a previous work Stucki [J.W. Stucki, Eur. J. Biochem. vol. 109, 269 (1980)] used a FOIT-approach to describe the modes of thermodynamic performance of oxidative phosphorylation involved in ATP-synthesis within mithochondrias. In that work the author did not use the mentioned loop-shaped curves and he proposed that oxidative phosphorylation operates in a steady state simultaneously at minimum entropy production and maximum efficiency, by means of a conductance matching condition between extreme states of zero and infinite conductances respectively. In the present work we show that all Stucki's results about the oxidative phosphorylation energetics can be obtained without the so-called conductance matching condition. On the other hand, we also show that the minimum entropy production state implies both null power output and efficiency and therefore this state is not fulfilled by the oxidative phosphorylation performance. Our results suggest that actual efficiency values of oxidative phosphorylation performance are better described by a mode of operation consisting in the simultaneous maximization of the so-called ecological function and the efficiency.Comment: 20 pages, 7 figures, submitted to Phys. Rev.

Theoretical study of incoherent phi photoproduction on a deuteron target

We study the photoproduction of phi mesons in deuteron, paying attention to the modification of the cross section from bound protons to the free ones with the aim of comparing with recent results at LEPS. For this purpose we take into account Fermi motion in single scattering and rescattering of the phi to account for phi absorption on a second nucleon as well as the rescattering of the proton. We find that the contribution of the double scattering is much smaller than the typical cross section of gamma p to phi p in free space, which implies a very small screening of the phi production in deuteron. The contribution from the proton rescattering, on the other hand, is found to be not negligible compared to the cross section of gamma p to phi p in free space, and leads to a moderate reduction of the phi photoproduction cross section on a deuteron at forward angles if LEPS set up is taken into account. The Fermi motion allows contribution of the single scattering in regions forbidden by phase space in the free case. In particular, we find that for momentum transferred squared close to the maximum value, the Fermi motion changes drastically the shape of d sigma / dt, to the point that the ratio of this cross section to the free one becomes very sensitive to the precise value of t chosen, or the size of the bin used in an experimental analysis. Hence, this particular region of t does not seem the most indicated to find effects of a possible phi absorption in the deuteron. This reaction is studied theoretically as a function of t and the effect of the experimental angular cuts at LEPS is also discussed, providing guidelines for future experimental analyses of the reaction.Comment: 17 pages, 16 figure

Degradation of seventeen contaminants of emerging concern in municipal wastewater effluents by sonochemical advanced oxidation processes

The simultaneous degradation of seventeen emerging concern pollutants in effluent from the municipal wastewater treatment plant (MWTP) of Bogotá-Colombia was studied using high frequency ultrasound (375 kHz). The considered compounds in the effluent corresponded to pharmaceuticals (diclofenac, carbamazepine, venlafaxine, ciprofloxacin, norfloxacin, valsartan, losartan, irbesartan, sulfamethoxazole, clarithromycin, azithromycin, erythromycin, metronidazole, trimethoprim and the high potentiality of the sono-photo-Fenton/oxalic acid system for the pollutants elimination in real-world wastewater matrices. clindamycin); cocaine and its major metabolite benzoylecgonine. Due to limitation of the MWTP for the pollutants elimination, ultrasound was applied to remove these compounds. Interestingly, ultrasonic physical action led to releasing of ciprofloxacin, norfloxacin, diclofenac and sulfamethoxazole from suspended solids, whereas the chemical effects induced degradation of the rest of compounds. For the latter ones, an interesting correlation between the sonodegradation and arithmetic multiplication between hydrophobicity and concentration of pollutants was established. Afterwards, the sonochemical process was complemented with ferrous ions (sono-Fenton), ferrous ions plus light (sono-photo-Fenton) or ferrous ions plus light in presence of oxalic acid (sono-photo-Fenton/oxalic acid). Additionally, to clarify fundamental aspects of the different systems, individual treatments in distilled water of a model pollutant (valsartan) were performed. The complemented processes significantly enhanced all compounds degradation, following the order: sono-photo-Fenton/oxalic acid > sono-photo-Fenton ~ sono-Fenton > sonochemistry. The Fe2+ addition improved the pollutants elimination by generation of more hydroxyl radicals in the solution bulk. Meanwhile, oxalic acid avoided Fe3+ precipitation favoring the iron catalytic cycle. Thus, the work demonstrate

TLR9 ligation in pancreatic stellate cells promotes tumorigenesis

Modulation of Toll-like receptor (TLR) signaling can have protective or protumorigenic effects on oncogenesis depending on the cancer subtype and on specific inflammatory elements within the tumor milieu. We found that TLR9 is widely expressed early during the course of pancreatic transformation and that TLR9 ligands are ubiquitous within the tumor microenvironment. TLR9 ligation markedly accelerates oncogenesis, whereas TLR9 deletion is protective. We show that TLR9 activation has distinct effects on the epithelial, inflammatory, and fibrogenic cellular subsets in pancreatic carcinoma and plays a central role in cross talk between these compartments. Specifically, TLR9 activation can induce proinflammatory signaling in transformed epithelial cells, but does not elicit oncogene expression or cancer cell proliferation. Conversely, TLR9 ligation induces pancreatic stellate cells (PSCs) to become fibrogenic and secrete chemokines that promote epithelial cell proliferation. TLR9-activated PSCs mediate their protumorigenic effects on the epithelial compartment via CCL11. Additionally, TLR9 has immune-suppressive effects in the tumor microenvironment (TME) via induction of regulatory T cell recruitment and myeloid-derived suppressor cell proliferation. Collectively, our work shows that TLR9 has protumorigenic effects in pancreatic carcinoma which are distinct from its influence in extrapancreatic malignancies and from the mechanistic effects of other TLRs on pancreatic oncogenesis

Um Jogo Educativo na Web no Contexto do Ensino Fundamental

Este artigo tem como objetivo apresentar o Sim Investigador, um jogo que busca motivar o estudante através do lúdico com a construção e resolução de casos (histórias) envolvendo o conteúdo de uma disciplina, e desenvolvido para estudantes do ensino fundamental e médio. No Sim Investigador o estudante receberá o papel de um investigador no qual deverá solucionar casos utilizando seus conhecimentos aprendidos na escola ou colégio, como também poderá construir suas próprias histórias no contexto de um conteúdo programático proposto por um professor, se aprofundando no conteúdo estudado. Um estudo de caso foi realizado com 49 estudantes de três escolas. Os resultados obtidos no estudo de caso mostra que 69,38% dos estudantes informaram se sentir ainda mais motivados ao estudo com o uso do jogo Sim Investigador