Addressing the thermal performance gap: Possible performance control tools for the construction manager

Construction practice has failed to deliver buildings that consistently meet their expected thermal performance; however, examples of good practice do exist. Buildings can be designed and built within acceptable tolerances and meet nearly zero carbon standards. Unfortunately, due to the negative implications associated with the performance gap there have been attempts to divert attention from measurement, with some being critical of methods that were used to identify the variance in building performance. However, the tools have proven reliable and the practice of thermal measurement which was once limited to scientists is finding its place in industry. Measurement is becoming more accepted and different tools are being used to assess thermal performance. The tools can add value to inspections, building surveys and assist with quality control. Construction professionals, not least construction managers, are gaining valuable insights through research undertaken and observations gained. The tests reviewed provide new methods of capturing evidence on building performance, thus allowing valuable information on the quality of design, workmanship and process to be gained. Use of thermal measurement and analysis tools should result in further improvements to building performance. The data from major performance evaluation projects are reviewed and presente

Electro-chemical machining

This report introduces the reader to the process and to the requirements which must be considered for its installation on the shop floor. Although only electro-chemical shaping is dealt with, many of the parameters investigated are fundamental to other configurations. The machining characteristics of several high strength alloys and die steels have been investigated; also of aluminium and mild steel. Electrolyte heating effects and the physical attributes of the machined surface have been considered. Electrode and workpiece shapes have been simulated for static field examinations and these followed by investigations under dynamic machining conditions

An analysis of errors in the Energy Performance certificate database

Energy Performance Certificates (EPCs) are the adopted method by which the UK government tracks the progress of its domestic energy efficiency policies. Over 15 million EPCs have been lodged, representing a valuable resource for research into the UK building stock. However, the EPC record has a reputation of containing multiple errors. In this work, we identify many such errors and quantify how common they are. We find that 27% of EPCs in the open EPC record display at least one flag to suggests it is incorrect and estimate the true error rate of the EPC record to be between 36 and 62%. Many of these errors are caused by EPC assessors disagreeing on building parameters such as floor type, wall type and built form. Additionally, flats and maisonettes appear to cause more issues than other property types. This may be due to difficulties in assessing their location in the building and the nature of the surrounding space. We also suggest potential new methods of quality assurance which rely on machine learning and which could allow such errors to be avoided in the future

Lymph node homing cells biologically enriched for γδ T cells express multiple genes from the T19 repertoire

Sheep γδ T cells have been shown serologically to express T19, a membrane protein of 180-200 kDa which is a member of the scavenger receptor superfamily. Previous work from this laboratory resulted in the detection of a multigene family of T19-like genes in the sheep genome. In this study nucleotide sequences from several T19 genes were determined and are reported along with the corresponding segments of a number of expressed mRNA molecules. A segment of a single sheep T19-like gene was sequenced and these data, along with the corresponding sequences from cloned T19-like cDNA molecules from sheep and cow, were used to design an ollgonucleotide primer system suitable for amplification of corresponding segments of many T19 genes and their cDNAs. Between 30 and 40% of cloned T19 genes were amenable to amplification using the selected primers, and sequence analysis of cloned PCR products confirmed that different T19 genes encode unique amino acid sequences. The expression of multiple T19 genes was established using cDNA molecules obtained from a single sample of sheep lymphocyte mRNA. The possible role of the T19 family of genes is discusse

What are the effects of nature conservation on human well-being? A systematic map of empirical evidence from developing countries

This is the final version of the article. Available from BioMed Central via the DOI in this record.Background: Global policy initiatives and international conservation organizations have sought to emphasize and strengthen the link between the conservation of natural ecosystems and human development. While many indices have been developed to measure various social outcomes to conservation interventions, the quantity and strength of evidence to support the effects, both positive and negative, of conservation on different dimensions of human well-being, remain unclear, dispersed and inconsistent. Methods: We searched 11 academic citation databases, two search engines and 30 organisational websites for relevant articles using search terms tested with a library of 20 relevant articles. Key informants were contacted with requests for articles and possible sources of evidence. Articles were screened for relevance against predefined inclusion criteria at title, abstract and full text levels according to a published protocol. Included articles were coded using a questionnaire. A critical appraisal of eight systematic reviews was conducted to assess the reliability of methods and confidence in study findings. A visual matrix of the occurrence and extent of existing evidence was also produced. Results: A total of 1043 articles were included in the systematic map database. Included articles measured effects across eight nature conservation-related intervention and ten human well-being related outcome categories. Linkages between interventions and outcomes with high occurrence of evidence include resource management interventions, such as fisheries and forestry, and economic and material outcomes. Over 25 % of included articles examined linkages between protected areas and aspects of economic well-being. Fewer than 2 % of articles evaluated human health outcomes. Robust study designs were limited with less than 9 % of articles using quantitative approaches to evaluate causal effects of interventions. Over 700 articles occurred in forest biomes with less than 50 articles in deserts or mangroves, combined. Conclusions: The evidence base is growing on conservation-human well-being linkages, but biases in the extent and robustness of articles on key linkages persist. Priorities for systematic review, include linkages between marine resource management and economic/material well-being outcomes; and protected areas and governance outcomes. Greater and more robust evidence is needed for many established interventions to better understand synergies and trade-offs between interventions, in particular those that are emerging or contested.This study was made possible by a grant from the Gordon and Betty Moore Foundation to Conservation International (Grant No. 3519). This research was conducted by the Evidence-based Conservation Working Group and financially supported in part by SNAP: Science for Nature and People, a collaboration of The Nature Conservancy, the Wildlife Conservation Society and the National Center for Ecological Analysis and Synthesis (NCEAS)

The long-term safety and efficacy of bilateral transplantation of human fetal striatal tissue in patients with mild to moderate Huntington's disease.

Huntington's disease (HD) is a fatal autosomal dominant neurodegenerative disease involving progressive motor, cognitive and behavioural decline, leading to death approximately 20 years after motor onset. The disease is characterised pathologically by an early and progressive striatal neuronal cell loss and atrophy, which has provided the rationale for first clinical trials of neural repair using fetal striatal cell transplantation. Between 2000 and 2003, the 'NEST-UK' consortium carried out bilateral striatal transplants of human fetal striatal tissue in five HD patients. This paper describes the long-term follow up over a 3-10-year postoperative period of the patients, grafted and non-grafted, recruited to this cohort using the 'Core assessment program for intracerebral transplantations-HD' assessment protocol. No significant differences were found over time between the patients, grafted and non-grafted, on any subscore of the Unified Huntington's Disease Rating Scale, nor on the Mini Mental State Examination. There was a trend towards a slowing of progression on some timed motor tasks in four of the five patients with transplants, but overall, the trial showed no significant benefit of striatal allografts in comparison with a reference cohort of patients without grafts. Importantly, no significant adverse or placebo effects were seen. Notably, the raclopride positron emission tomography (PET) signal in individuals with transplants, indicated that there was no obvious surviving striatal graft tissue. This study concludes that fetal striatal allografting in HD is safe. While no sustained functional benefit was seen, we conclude that this may relate to the small amount of tissue that was grafted in this safety study compared with other reports of more successful transplants in patients with HD

Barriers to domestic retrofit quality: Are failures in retrofit standards a failure of retrofit standards?

Thermal retrofits of homes are central to the UK's fuel poverty and net zero carbon policies but there are concerns about poor quality installation and so new standards are to be introduced (PAS2035). We have explored retrofit installers' perceptions of the barriers to installing internal wall insulation (IWI) and of current regulations and standards for retrofits. We conducted four focus groups with retrofit installers. Thematic analysis identified three themes. (1) IWI is viewed as impractical in situations other than new builds, extensions and conversions as it is too time-consuming and expensive. (2) Installing IWI is perceived as an unskilled job with no need for training or referring to standards during installation. (3) Because standards lack credibility, installers can be sceptical of potential problems caused by on-site installation adaptations, for example thermal bridging. Our results show that retrofit standards have not improved retrofit quality. Awareness and credibility of standards is low, and new standards (PAS2035) will introduce additional costs which may reduce the pool of installers willing to engage in the retrofit market. Policies need to address installer training, professional identity and social practices, and reduce barriers to change in order to increase success. </jats:p

Tracking the hydro-climatic signal from lake to sediment: a field study from central Turkey

Palaeo-hydrological interpretations of lake sediment proxies can benefit from a robust understanding of the modern lake environment. In this study, we use Nar Gölü, a non-outlet, monomictic maar lake in central Turkey, as a field site for a natural experiment using observations and measurements over a 17-year monitoring period (1997–2014). We compare lake water and sediment trap data to isotopic, chemical and biotic proxies preserved in its varved sediments. Nar Gölü underwent a 3 m lake-level fall between 2000 and 2010. δ18Olakewater is correlated with this lake-level fall, responding to the change in water balance. Endogenic carbonate is shown to precipitate in isotopic equilibrium with lake water and there is a strong relationship between δ18Olakewater and δ18Ocarbonate, which suggests the water balance signal is accurately recorded in the sediment isotope record. Over the same period, sedimentary diatom assemblages also responded, and conductivity inferred from diatoms showed a rise. Shifts in carbonate mineralogy and elemental chemistry in the sediment record through this decade were also recorded. Intra-annual changes in δ18Olakewater and lake water chemistry are used to demonstrate the seasonal variability of the system and the influence this may have on the interpretation of δ18Ocarbonate. We use these relationships to help interpret the sedimentary record of changing lake hydrology over the last 1725 years. Nar Gölü has provided an opportunity to test critically the chain of connection from present to past, and its sedimentary record offers an archive of decadal- to centennial-scale hydro-climatic chang

IWI Thermal Properties and the Risk of Condensation and Mould GrowthImposed upon Neighbors at a Party Wall Junction

Internal wall insulation (IWI) is one of the few retrofit approaches to reduce heat loss through solid brick walls. Discontinuities in the insulation layer can result in thermal bridges, leading to reduced surface temperatures and the potential for condensation to form. Party wall junctions retrofitted with IWI act as discontinuities when neighbouring homes do not have IWI, leading to reduced surface temperatures on the neighbouring side. The condensation risk imposed on the uninsulated neighbour by a range of notional IWI systems are simulated, the resulting temperature factors indicate whether each system imposes a risk upon the uninsulated neighbour. Thicker, higher performing IWI systems were found to result in greater risk in the neighbouring property