378 research outputs found

    Screening of lupin varieties for organic mixed cropping in Switzerland

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    Screening of Lupin Varieties for Organic Mixed Cropping in Switzerland

    Relating the Time Complexity of Optimization Problems in Light of the Exponential-Time Hypothesis

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    Obtaining lower bounds for NP-hard problems has for a long time been an active area of research. Recent algebraic techniques introduced by Jonsson et al. (SODA 2013) show that the time complexity of the parameterized SAT(⋅\cdot) problem correlates to the lattice of strong partial clones. With this ordering they isolated a relation RR such that SAT(RR) can be solved at least as fast as any other NP-hard SAT(⋅\cdot) problem. In this paper we extend this method and show that such languages also exist for the max ones problem (MaxOnes(Γ\Gamma)) and the Boolean valued constraint satisfaction problem over finite-valued constraint languages (VCSP(Δ\Delta)). With the help of these languages we relate MaxOnes and VCSP to the exponential time hypothesis in several different ways.Comment: This is an extended version of Relating the Time Complexity of Optimization Problems in Light of the Exponential-Time Hypothesis, appearing in Proceedings of the 39th International Symposium on Mathematical Foundations of Computer Science MFCS 2014 Budapest, August 25-29, 201

    Dietary cholesterol promotes repair of demyelinated lesions in the adult brain

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    Multiple Sclerosis (MS) is an inflammatory demyelinating disorder in which remyelination failure contributes to persistent disability. Cholesterol is rate-limiting for myelin biogenesis in the developing CNS; however, whether cholesterol insufficiency contributes to remyelination failure in MS, is unclear. Here, we show the relationship between cholesterol, myelination and neurological parameters in mouse models of demyelination and remyelination. In the cuprizone model, acute disease reduces serum cholesterol levels that can be restored by dietary cholesterol. Concomitant with blood-brain barrier impairment, supplemented cholesterol directly supports oligodendrocyte precursor proliferation and differentiation, and restores the balance of growth factors, creating a permissive environment for repair. This leads to attenuated axon damage, enhanced remyelination and improved motor learning. Remarkably, in experimental autoimmune encephalomyelitis, cholesterol supplementation does not exacerbate disease expression. These findings emphasize the safety of dietary cholesterol in inflammatory diseases and point to a previously unrecognized role of cholesterol in promoting repair after demyelinating episodes

    Query Answering in Normal Logic Programs under Uncertainty

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    We present a simple, yet general top-down query answering procedure for normal logic programs over lattices and bilattices, where functions may appear in the rule bodies. Its interest relies on the fact that many approaches to paraconsistency and uncertainty in logic programs with or without non-monotonic negation are based on bilattices or lattices, respectively

    GRS 1915+105 : High-energy Insights with SPI/INTEGRAL

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    We report on results of two years of INTEGRAL/SPI monitoring of the Galactic microquasar GRS 1915+105. From September 2004 to May 2006, the source has been observed twenty times with long (approx 100 ks) exposures. We present an analysis of the SPI data and focus on the description of the high-energy (> 20 keV) output of the source. We found that the 20 - 500 keV spectral emission of GRS 1915+105 was bound between two states. It seems that these high-energy states are not correlated with the temporal behavior of the source, suggesting that there is no direct link between the macroscopic characteristics of the coronal plasma and the the variability of the accretion flow. All spectra are well fitted by a thermal comptonization component plus an extra high-energy powerlaw. This confirms the presence of thermal and non-thermal electrons around the black hole.Comment: 7 pages, 8 figures, 2 tables; accepted (09/11/2008) for publication in A&

    Image-based Search and Retrieval for Biface Artefacts using Features Capturing Archaeologically Significant Characteristics

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    Archaeologists are currently producing huge numbers of digitized photographs to record and preserve artefact finds. These images are used to identify and categorize artefacts and reason about connections between artefacts and perform outreach to the public. However, finding specific types of images within collections remains a major challenge. Often, the metadata associated with images is sparse or is inconsistent. This makes keyword-based exploratory search difficult, leaving researchers to rely on serendipity and slowing down the research process. We present an image-based retrieval system that addresses this problem for biface artefacts. In order to identify artefact characteristics that need to be captured by image features, we conducted a contextual inquiry study with experts in bifaces. We then devised several descriptors for matching images of bifaces with similar artefacts. We evaluated the performance of these descriptors using measures that specifically look at the differences between the sets of images returned by the search system using different descriptors. Through this nuanced approach, we have provided a comprehensive analysis of the strengths and weaknesses of the different descriptors and identified implications for design in the search systems for archaeology
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