12 research outputs found
Siderophores as anchors in artificial metalloenzymes
Fundacao de Amparo a Pesquisa do Estado de Sao PauloConselho Nacional de Desenvolvimento Cientifico e TecnologicoCAPESInst Chem UNESP, Araraquara, SP, Brazil|Univ Fed Sao Paulo, EPM, Dept Pharmacol, Sao Paulo, SP, BrazilInst Chem USP, Sao Carlos, SP, BrazilUniv Fed Sao Paulo, EPM, Dept Pharmacol, Sao Paulo, SP, BrazilFAPESP: 2016/177115CNPqCAPESWeb of Scienc
Synthesis, characterization, and thermal behavior of palladium(II) coordination compounds containing isonicotinamide
Palladium(II) coordination compounds of general formula trans-[PdX(2)(isn)(2)], X = Cl(-) (1), N(3) (-) (2), SCN(-) (3), NCO(-) (4), isn = isonicotinamide; were synthesized and characterized in solid state by elemental analysis, infrared spectroscopy, and simultaneous TG-DTA. TG experiments reveal that the compounds 1-4 undergo thermal decomposition in three or four stages, yielding Pd(0) as final residue, according to calculus and identification by X-ray powder diffraction
Synthesis, characterization, and thermal behavior of palladium(II) coordination compounds containing isonicotinamide
Pedagogical training profile of basic health sciences faculty in biomedical and related fields at Brazilian public and private higher education institutions
Pyrazolyl Pd(II) complexes containing triphenylphosphine: Synthesis and antimycobacterial activity
Complexes of the type trans-[PdCl2(HL)(PPh3)], where HL = pyrazole (1); 3,5-dimethylpyrazole (2); 4-nitropyrazole (3); 4-iodopyrazole (4) and PPh3 = triphenylphosphine, were synthesized and characterized by elemental analyses, infrared and H-1 NMR spectroscopies. Single-crystal X-ray diffraction determination on 3.0.9 CHCl3 and 4 showed that the coordination geometry around Pd(II) is nearly square-planar, with the chloro ligands in a trans configuration. In vitro antimycobacterial evaluation demonstrated that compound 4 displayed a minimum inhibitory concentration (MIC) of 7.61 +/- 2.18 mu M, being superior to the values observed for some commonly used antituberculosis drugs and other metal-based complexes. (C) 2015 Elsevier Ltd. All rights reserved