139 research outputs found

    The work of community gardens: reclaiming place for community in the city

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    The growth of community gardens has become the source of much academic debate regarding their role in community empowerment in the contemporary city. In this article, we focus upon the work being done in community gardens, using gardening in Glasgow as a case study. We argue that while community gardening cannot be divorced from more regressive underlying economic and social processes accompanying neoliberal austerity policies, it does provide space for important forms of work that address social needs and advance community empowerment. In developing this argument we use recent geographical scholarship concerning the generative role of place in bringing together individuals and communities in new collective forms of working. Community gardens are places that facilitate the recovery of individual agency, construction of new forms of knowledge and participation, and renewal of reflexive and proactive communities that provide broader lessons for building more progressive forms of work in cities

    Patent Law: Synergism Rejected

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    Patent Law: Synergism Rejected

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    Social centres, anarchism and the struggle for Glasgow's Commons

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    This thesis charts the work of a group of people in their efforts to set up a social centre in Glasgow. A social centre is like our once prolific community centre but with an explicit political character and agenda. They are social and cultural hubs where people can take part in a variety of communal events (e.g. dancing, cooking, eating, game play or simply hanging around). They are also places that encourage political debate, organization and action. Crucially, users are encouraged to participate in the day-to-day running of the centres. Social centres have a rich history in European radical politics. While proponents of various political philosophies use social centres, they are most commonly associated with anarchism. Anarchism is a tradition of political thought and practice that aims to build a society based on mutual aid and mass democratic participation characterised by a rejection of all forms of human domination over other humans. In this work I explore a variety of political and cultural initiatives employed by anarchist-influenced activists in Glasgow as they struggle against the neoliberalization of the city. It is the intention of this thesis to highlight the totalizing impositions of neoliberal urban governance and anarchist-inspired alternatives to these impositions, which I argue, constitute a different way of knowing and engaging with the city. These alternatives are prefigured in the doing of social centre work

    Identification and characterization of MUS81 point mutations that abolish interaction with the SLX4 scaffold protein

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    AbstractMUS81-EME1 is a conserved structure-selective endonuclease with a preference for branched DNA substrates in vitro that correspond to intermediates of DNA repair. Cells lacking MUS81 or EME1 show defects in the repair of DNA interstrand crosslinks (ICL) resulting in hypersensitivity to agents such as mitomycin C. In metazoans, a proportion of cellular MUS81-EME1 binds the SLX4 scaffold protein, which is itself instrumental for ICL repair. It was previously reported that mutations in SLX4 that abolished interaction with MUS81 affected ICL repair in human cells but not in murine cells. In this study we looked the other way around by pinpointing amino acid residues in MUS81 that when mutated abolish the interaction with SLX4. These mutations fully rescued the mitomycin C hypersensitivity of MUS81 knockout murine cells, but they were unable to rescue the sensitivity of two different human cell lines defective in MUS81. These data support an SLX4-dependent role for MUS81 in the repair, but not the induction of ICL-induced double-strand breaks. This study sheds light on the extent to which MUS81 function in ICL repair requires interaction with SLX4

    Military maladaptation : counterinsurgency and the politics of failure

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    Tactical learning is critical to battlefield success, especially in a counterinsurgency. This article tests the existing model of military adaption against a ‘most-likely’ case: the British Army’s counterinsurgency in the Southern Cameroons (1960–61). Despite meeting all preconditions thought to enable adaptation – decentralization, leadership turnover, supportive leadership, poor organizational memory, feedback loops, and a clear threat – the British still failed to adapt. Archival evidence suggests politicians subverted bottom-up adaptation, because winning came at too high a price in terms of Britain’s broader strategic imperatives. Our finding identifies an important gap in the extant adaptation literature: it ignores politics.PostprintPeer reviewe

    John Clare and place

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    This chapter tackles issues of place in the self-presentation and critical reception of John Clare, and pursues it across a number of axes. The argument centres on the placing of Clare both socio-economically and ‘naturally’, and limitations exerted upon perceptions of his work. Interrogating criticism this chapter finds a pervasive awkwardness especially in relation to issues of class and labour. It assesses the contemporary ‘placing’ of Clare, and seemingly unavoidable insensitivities to labour and poverty in the history industry, place-naming, and polemical ecocriticism. It assesses the ways Clare represents place – in poverty, in buildings, in nature – and, drawing on Michel de Certeau, considers the tactics Clare uses to negotiate his place. It pursues trajectories to ‘un-place’ Clare: the flight of fame in Clare’s response to Byron; and the flight of an early poem in songbooks and beyond, across the nineteenth century
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